General Information of Drug (ID: DMVWUCF)

Drug Name
Sucrose Drug Info
Synonyms
sucrose; saccharose; 57-50-1; Cane sugar; sugar; Table sugar; White sugar; D-Sucrose; Saccharum; Rohrzucker; Amerfand; Sucrose, pure; Sucrose, dust; D(+)-Saccharose; sacarosa; D(+)-Sucrose; D-(+)-Saccharose; beta-D-Fructofuranosyl alpha-D-glucopyranoside; Microse; Amerfond; Granulated sugar; Rock candy; Beet sugar; Sucraloxum [INN-Latin]; beta-D-Fructofuranosyl-alpha-D-glucopyranoside; Confectioner's sugar; HSDB 500; Sacharose; CCRIS 2120; Sucrose [USAN:JAN]; alpha-D-Glucopyranosyl beta-D-fructofuranoside; CHEBI:17992; D-Saccharose
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5988
ChEBI ID
CHEBI:17992
CAS Number
CAS 57-50-1
TTD Drug ID
DMVWUCF
VARIDT Drug ID
DR00131
INTEDE Drug ID
DR2151

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tazobactam DM3XNUI Appendicitis DB10 Approved [14]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [15]
CAZ AVI DMPG4OM Serious infection 1H0Z Phase 3 [16]
Enmetazobactam DMZKTYJ Urinary tract infection GC08 Phase 3 [17]
Vaborbactam DMDCFXJ Urinary tract infection GC08 Phase 3 [18]
MK-7655 DMLMV0O Bacterial infection 1A00-1C4Z Phase 2 [19]
CXL DM3JFZ2 Methicillin-resistant staphylococci infection 1A00-1A09 Phase 2 [20]
RASV-Sp DM4VTX6 Streptococcus infection 1B53 Phase 1 [21]
ME-1071 DMEMQ5J Bacterial infection 1A00-1C4Z Phase 1 [22]
OP-0595 DMECVP9 Bacterial infection 1A00-1C4Z Phase 1 [23]
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Drug(s) Metabolized By Fructokinase (scrK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Maltose DMH0ROP N. A. N. A. Phase 1/2 [6]
Drug(s) Metabolized By Beta-fructofuranosidase (BFRU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Kestose DML93TN N. A. N. A. Preclinical [7]
Drug(s) Metabolized By Glucansucrase (gtf106B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
RESORCINOL DMM37C0 Discovery agent N.A. Investigative [24]
CATECHOL DML0YEK Discovery agent N.A. Investigative [25]
ETHYLGALLATE DMJ6PB8 Discovery agent N.A. Investigative [26]
PYROGALLOL DMG5KDY Discovery agent N.A. Investigative [27]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Kestose DML93TN N. A. N. A. Preclinical [7]
Drug(s) Metabolized By Sucrose phosphorylase (Spase)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Kestose DML93TN N. A. N. A. Preclinical [7]
Drug(s) Affected By Insulin (INS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Epinephrine DM3KJBC Acute asthma CA23 Approved [30]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [31]
Fructose DM43AN2 Vomiting MD90 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [34]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [35]
Propranolol DM79NTF Angina pectoris BA40 Approved [36]
Testosterone DM7HUNW Hot flushes GA30 Approved [37]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [38]
Quercetin DM3NC4M Obesity 5B81 Approved [39]
Fructose DM43AN2 Vomiting MD90 Approved [13]
Oxcarbazepine DM5PU6O Epilepsy 8A60-8A68 Approved [40]
Estrone DM5T6US Acne vulgaris ED80 Approved [41]
Testosterone DM7HUNW Hot flushes GA30 Approved [42]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Dienestrol DMBSXI0 Atrophic vaginitis GA30.2 Approved [41]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [41]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [41]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [44]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [45]
Diazepam DM08E9O Alcohol withdrawal Approved [46]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [47]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [10]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [50]
Isradipine DMA5XGH Hypertension BA00-BA04 Approved [51]
Valdecoxib DMAY7H4 Osteoarthritis FA00-FA05 Approved [52]
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Drug(s) Affected By Neurotensin/neuromedin N (NTS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [12]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [53]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [55]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [57]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [58]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [59]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [60]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [54]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [61]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [39]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [63]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [63]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [64]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [65]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [66]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Staphylococcus Beta-lactamase (Stap-coc blaZ) TTHI19T BLAC_STAAU Inhibitor [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Solute carrier family 45 member 4 (SLC45A4) DTKPHZ6 S45A4_HUMAN Substrate [3]
Solute carrier family 45 member 3 (SLC45A3) DTGEFXH S45A3_HUMAN Substrate [4]
Membrane-associated transporter protein (SLC45A2) DTNCJAT S45A2_HUMAN Substrate [5]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Fructokinase (scrK) DEBW1FU SCRK_FUSMR Substrate [6]
Sucrose phosphorylase (Spase) DEJ4FO2 A0A0M4N1J6_BIFLN Substrate [7]
Glucansucrase (gtf106B) DEWRN24 Q5SBN3_LACRE Substrate [8] , [9]
Beta-fructofuranosidase (BFRU) DECWNTP E1CPU3_BIFLN Substrate [7]
Sucrose-6-phosphate hydrolase scrB (ScrB) DEICTXP B0MAC0_ANACD Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Fibroblast growth factor 2 (FGF2) OT7YUJ9F FGF2_HUMAN Gene/Protein Processing [10]
Insulin (INS) OTZ85PDU INS_HUMAN Gene/Protein Processing [11]
Neurotensin/neuromedin N (NTS) OTPGDNQS NEUT_HUMAN Gene/Protein Processing [12]
Proheparin-binding EGF-like growth factor (HBEGF) OTLU00JS HBEGF_HUMAN Gene/Protein Processing [10]
Sex hormone-binding globulin (SHBG) OTPWU5IW SHBG_HUMAN Gene/Protein Processing [13]

References

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24 Increased infections with beta-blocker use in ischemic stroke, a beta2-receptor mediated process? Neurol Sci. 2017 Jun;38(6):967-974.
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41 Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and -fetoprotein. Toxicol Sci. 2015 Feb;143(2):333-48. doi: 10.1093/toxsci/kfu231. Epub 2014 Oct 27.
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43 Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro. Toxicol In Vitro. 2015 Apr;29(3):489-501.
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50 Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Toxicol Appl Pharmacol. 2012 Jun 1;261(2):204-16.
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52 The effect of valdecoxib on the production of growth factors evoked by hypoxia and bacterial lipopolysaccharide in HMEC-1 cells. Adv Clin Exp Med. 2013 Nov-Dec;22(6):795-800.
53 Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration. Arch Toxicol. 2016 Jan;90(1):159-80.
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61 Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1. Redox Biol. 2020 Jan;28:101321. doi: 10.1016/j.redox.2019.101321. Epub 2019 Sep 5.
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64 Endoplasmic reticulum stress contributes to arsenic trioxide-induced intrinsic apoptosis in human umbilical and bone marrow mesenchymal stem cells. Environ Toxicol. 2016 Mar;31(3):314-28.
65 Keratinocyte-derived IL-36gama plays a role in hydroquinone-induced chemical leukoderma through inhibition of melanogenesis in human epidermal melanocytes. Arch Toxicol. 2019 Aug;93(8):2307-2320.
66 THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders. Transl Psychiatry. 2018 Apr 25;8(1):89. doi: 10.1038/s41398-018-0137-3.
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