Details of Disease

General Information of Disease (ID: DIS28ZSZ)

• Disease Name: Staphylococcal pneumonia
• Synonyms: Staphylococcus pneumonia; Staphylococcus caused pneumonia
• Definition: Pneumonia caused by infections with bacteria of the genus staphylococcus, usually with staphylococcus aureus.
• Disease Hierarchy:
  DIS8EF3M: Pneumonia
  DISY8WGS: Staphylococcus infection
  DISPW7PH: Bacterial pneumonia
  DIS28ZSZ: Staphylococcal pneumonia
• Disease Identifiers:
  MONDO ID: MONDO_0005970
  MESH ID: D011023
  UMLS CUI: C0032308
  MedGen ID: 18532
  SNOMED CT ID: 22754005

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 32 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Amikacin	DM5PDRB	Approved	Small molecular drug	[1]
Ampicillin	DMHWE7P	Approved	Small molecular drug	[2]
Cefamandole	DMNEXZF	Approved	Small molecular drug	[3]
Cefazolin	DMPDYFR	Approved	Small molecular drug	[4]
Cefmetazole	DM42W1B	Approved	Small molecular drug	[5]
Cefotaxime	DMEB837	Approved	NA	[6]
Cefotetan	DM07TX3	Approved	Small molecular drug	[7]
Cefoxitin	DMY8NC4	Approved	NA	[8]
Cefradine	DMUNSWV	Approved	Small molecular drug	[9]
Ceftazidime	DM41GRA	Approved	Small molecular drug	[10]
Ceftizoxime	DM3VOGS	Approved	Small molecular drug	[11]
Ceftriaxone	DMCEW64	Approved	Small molecular drug	[12]
Cefuroxime	DMSIMD8	Approved	Small molecular drug	[13]
Cephapirin	DMV2JNY	Approved	Small molecular drug	[14]
Clavulanate	DM2FGRT	Approved	Small molecular drug	[15]
Clindamycin	DM15HL8	Approved	Small molecular drug	[16]
Cloxacillin	DMUTL7O	Approved	Small molecular drug	[17]
Dicloxacillin	DM8EU0Z	Approved	Small molecular drug	[18]
Fusidic Acid	DMWVCF3	Approved	Small molecular drug	[19]
Gatifloxacin	DMSL679	Approved	Small molecular drug	[20]
Levofloxacin	DMS60RB	Approved	Small molecular drug	[21]
Linezolid	DMGFPU2	Approved	Small molecular drug	[22]
Meticillin	DMIKHN0	Approved	Small molecular drug	[23]
Moxifloxacin	DMU8V4S	Approved	Small molecular drug	[24]
Nafcillin	DMN9RPO	Approved	Small molecular drug	[25]
Norfloxacin	DMIZ6W2	Approved	Small molecular drug	[26]
Ofloxacin	DM0VQN3	Approved	Small molecular drug	[27]
Oxacillin	DMTAFY4	Approved	Small molecular drug	[28]
Ticarcillin	DM4ME02	Approved	Small molecular drug	[29]
Tobramycin	DMUI0CH	Approved	Small molecular drug	[30]
Trovafloxacin	DM6AN32	Approved	Small molecular drug	[31]
Vancomycin	DM3JFIH	Approved	NA	[32]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
FN1	TTPJ921	Strong	Biomarker	[33]

References

• [1] Amikacin FDA Label
• [2] Ampicillin FDA Label
• [3] Cefamandole FDA Label
• [4] Cefazolin FDA Label
• [5] Cefmetazole FDA Label
• [6] Cefotaxime FDA Label
• [7] Cefotetan FDA Label
• [8] Cefoxitin FDA Label
• [9] Cefazolin. Ann Intern Med. 1978 Nov;89(5 Pt 1):650-6.
• [10] Ceftazidime FDA Label
• [11] Ceftizoxime FDA Label
• [12] Ceftriaxone FDA Label
• [13] Cefuroxime FDA Label
• [14] Cephapirin FDA Label
• [15] Clavulanate FDA Label
• [16] Clindamycin FDA Label
• [17] Cloxacillin FDA Label
• [18] Dicloxacillin FDA Label
• [19] Fusidic acid in other infections. Int J Antimicrob Agents. 1999 Aug;12 Suppl 2:S11-5.
• [20] Gatifloxacin FDA Label
• [21] Levofloxacin FDA Label
• [22] Linezolid FDA Label
• [23] [Staphylococcal pneumonia]. Probl Tuberk Bolezn Legk. 2004;(6):11-7.
• [24] Moxifloxacin FDA Label
• [25] Nafcillin FDA Label
• [26] Norfloxacin FDA Label
• [27] Ofloxacin FDA Label
• [28] Oxacillin FDA Label
• [29] Ticarcillin FDA Label
• [30] Tobramycin FDA Label
• [31] Trovafloxacin FDA Label
• [32] Vancomycin FDA Label
• [33] Increased virulence of a fibronectin-binding protein mutant of Staphylococcus aureus in a rat model of pneumonia.Infect Immun. 2002 Jul;70(7):3865-73. doi: 10.1128/IAI.70.7.3865-3873.2002.