Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3JB6S)

Drug Name
5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole Drug Info
Synonyms
53-85-0; 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole; NSC 401575; Dichlororibofuranosylbenzimidazole; DRB; C12H12Cl2N2O4; 5,6-Dichlorobenzimidazole riboside; BRN 0039123; CHEMBL375530; UNII-8153319T3Q; 5,6-Dichloro-1-Beta-D-Ribofuranosyl-1h-Benzimidazole; 8153319T3Q; (2R,3R,4S,5R)-2-(5,6-Dichloro-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Benzimidazole, 5,6-dichloro-1-beta-D-ribofuranosyl-; 5,6-Dichloro-1-.beta.-D-ribofuranosylbenzimidazole
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5894
CAS Number
CAS 53-85-0
TTD Drug ID
DM3JB6S

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Casein kinase II alpha (CSNK2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CX-4945 DMWE7B9 Coronavirus infection 1D92 Phase 2 [8]
BALANOL DMDLN9E N. A. N. A. Terminated [9]
EMODIN DMAEDQG Coronavirus Disease 2019 (COVID-19) 1D6Y Terminated [2]
4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol DMSKJ1X Discovery agent N.A. Investigative [10]
4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole DMN9YOB Discovery agent N.A. Investigative [2]
ELLAGIC ACID DMX8BS5 Discovery agent N.A. Investigative [2]
APIGENIN DMI3491 Discovery agent N.A. Investigative [2]
PMID24900749C1a DMZPUSO Discovery agent N.A. Investigative [11]
AdoC(Dpr)2AlaArg6 DM2TWSZ Discovery agent N.A. Investigative [12]
PMID22115617C2c DMX5UKA Discovery agent N.A. Investigative [13]
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Drug(s) Affected By Tyrosine-protein kinase ABL1 (ABL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [14]
Anagrelide DMSQ8MD Thrombocythemia 3B63 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [15]
Quercetin DM3NC4M Obesity 5B81 Approved [16]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [17]
Testosterone DM7HUNW Hot flushes GA30 Approved [18]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [19]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [18]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [20]
Capsaicin DMGMF6V Back pain ME84.Z Approved [21]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [23]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [24]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [25]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [26]
Paclitaxel DMLB81S Breast carcinoma Approved [27]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [28]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [29]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [30]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [31]
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Drug(s) Affected By rRNA 2'-O-methyltransferase fibrillarin (FBL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [33]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [35]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [36]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [6]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [37]
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Drug(s) Affected By DNA-directed RNA polymerase II subunit RPB1 (POLR2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [38]
Methotrexate DM2TEOL Anterior urethra cancer Approved [39]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Panobinostat DM58WKG Chronic graft versus host disease Approved [42]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [17]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [43]
Deferasirox DM6ETS0 Beta thalassemia 3A50.2 Approved [44]
Leflunomide DMR8ONJ Arthritis FA20 Approved [45]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [36]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [47]
Selenium DM25CGV N. A. N. A. Approved [38]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [48]
Methotrexate DM2TEOL Anterior urethra cancer Approved [49]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [50]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [51]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [53]
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Drug(s) Affected By Sodium-coupled neutral amino acid symporter 2 (SLC38A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [43]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Fluoxetine DM3PD2C Bipolar depression Approved [55]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [56]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [57]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [58]
Leflunomide DMR8ONJ Arthritis FA20 Approved [45]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [35]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [36]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Casein kinase II alpha (CSNK2A1) TTER6YH CSK21_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [3]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Post-Translational Modifications [4]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A) OTHJQ1DZ RPB1_HUMAN Post-Translational Modifications [5]
rRNA 2'-O-methyltransferase fibrillarin (FBL) OTRODIE5 FBRL_HUMAN Protein Interaction/Cellular Processes [6]
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) OTALABSK S38A2_HUMAN Gene/Protein Processing [7]
Tyrosine-protein kinase ABL1 (ABL1) OT09YVXH ABL1_HUMAN Gene/Protein Processing [5]

References

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