Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBGHPE)

Drug Name
octanol Drug Info
Synonyms
1-octanol; Octan-1-ol; octanol; 111-87-5; N-octanol; Capryl alcohol; Octyl alcohol; caprylic alcohol; n-Octyl alcohol; Heptyl carbinol; 1-Hydroxyoctane; Primary octyl alcohol; Alcohol C-8; n-Octan-1-ol; Octilin; Sipol L8; Alfol 8; Lorol 20; Dytol M-83; n-Caprylic alcohol; 1-Octyl alcohol; n-Heptyl carbinol; EPAL 8; octyl-alcohol; Alcohols, C6-12; N-octyl-alcohol; Octyl alcohol, normal-primary; C8 alcohol; Fatty alcohol(C8); Octyl alcohol, primary; Caswell No. 611A; Octyl alcohol (natural); FEMA Number 2800; Lorol C 8-98; n-Capryl alcohol
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
957
ChEBI ID
CHEBI:16188
CAS Number
CAS 111-87-5
TTD Drug ID
DMBGHPE
INTEDE Drug ID
DR2004

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Investigative Drug(s)
Clinical Trial Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Gap junction alpha-8 protein (Cx50)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PQ-1 DMXLPO6 Solid tumour/cancer 2A00-2F9Z Investigative [13]
Drug(s) Targeting Gap junction alpha-1 protein (GJA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Granexin gel DMZS2R7 Diabetic foot ulcer BD54 Phase 3 [27]
Act1 DMXYRPO Wound healing EL8Y Phase 3 [28]
HCB1019 DMX8C6J Diabetic macular edema 9B71.02 Phase 2 [29]
ALMB-0168 DMB0LSF Osteosarcoma 2B51 Phase 1/2 [30]
ALMB-0166 DM3MH2H Spinal cord injury ND51.2 Phase 1 [31]
Drug(s) Metabolized By Alcohol dehydrogenase class-I gamma (ADH1C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [32]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [23]
Pyrene-1-aldehyde DMEF6IP N. A. N. A. Investigative [23]
Hydroxymethylpyrene DMPGAR2 N. A. N. A. Investigative [23]
BRN-2330710 DM87VP6 N. A. N. A. Investigative [23]
Pyrenemethanol DMGJ0RM N. A. N. A. Investigative [23]
Octanal DMTN0OK N. A. N. A. Investigative [23]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Metabolized By Alcohol dehydrogenase class-II (ADH4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [23]
ANDROSTERONE DMITJAK N. A. N. A. Phase 3 [33]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [23]
Pyrene-1-aldehyde DMEF6IP N. A. N. A. Investigative [23]
Hydroxymethylpyrene DMPGAR2 N. A. N. A. Investigative [23]
BRN-2330710 DM87VP6 N. A. N. A. Investigative [23]
Pyrenemethanol DMGJ0RM N. A. N. A. Investigative [23]
Octanal DMTN0OK N. A. N. A. Investigative [23]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [34]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [35]
Fructose DM43AN2 Vomiting MD90 Approved [36]
Ketoprofen DMRKXPT Bursitis Approved [36]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [38]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [39]
Gefitinib DM15F0X Colon adenocarcinoma Approved [40]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [41]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cystic fibrosis transmembrane conductance regulator (CFTR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivacaftor DMZC1HS Cystic fibrosis CA25 Approved [43]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [44]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [45]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
Miglustat DM5J64S Niemann-Pick disease type C Approved [47]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [48]
Milrinone DM8TUPF Congestive heart failure BD10 Approved [45]
Oxidized glutathione DM9EQC0 Breast cancer 2C60-2C65 Approved [49]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [49]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [50]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alcohol dehydrogenase class-3 (ADH5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [51]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [52]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [44]
Quercetin DM3NC4M Obesity 5B81 Approved [53]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [55]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [56]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [57]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [58]
Urethane DM7NSI0 N. A. N. A. Phase 4 [59]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Connexin-23 (Cx23) TTDQPXA CXE1_HUMAN Inhibitor [2]
Connexin-25 (Cx25) TTZ7POK CXB7_HUMAN Inhibitor [3]
Connexin-30 (Cx30) TTAU8SJ CXB6_HUMAN Inhibitor [4]
Connexin-32 (Cx32) TTHWA40 CXB1_HUMAN Inhibitor [5]
Connexin-45 (Cx45) TTEP7OC CXG1_HUMAN Inhibitor [6]
Connexin-59 (Cx59) TTYP9NL CXA9_HUMAN Inhibitor [7]
Connexin-62 (Cx62) TTQMI2N CXA10_HUMAN Inhibitor [8]
Gap junction alpha-1 protein (GJA1) TT4F7SL CXA1_HUMAN Inhibitor [9]
Gap junction alpha-3 protein (Cx46) TTFZRG0 CXA3_HUMAN Inhibitor [10]
Gap junction alpha-4 protein (Cx37) TTQO1VY CXA4_HUMAN Inhibitor [11]
Gap junction alpha-5 protein (Cx40) TTFQKZ7 CXA5_HUMAN Inhibitor [12]
Gap junction alpha-8 protein (Cx50) TTJ7ATH CXA8_HUMAN Inhibitor [13]
Gap junction beta-2 protein (Cx26) TTRGZX3 CXB2_HUMAN Inhibitor [14]
Gap junction beta-3 protein (Cx31) TTVRQ8L CXB3_HUMAN Inhibitor [15]
Gap junction beta-4 protein (Cx30.3) TTBRDFI CXB4_HUMAN Inhibitor [16]
Gap junction beta-5 protein (Cx31.1) TTL9MHP CXB5_HUMAN Inhibitor [17]
Gap junction delta-2 protein (Cx36) TTOZAFI CXD2_HUMAN Inhibitor [18]
Gap junction delta-3 protein (Cx31.9) TT7C18W CXD3_HUMAN Inhibitor [19]
Gap junction delta-4 protein (Cx40.1) TTL07NQ CXD4_HUMAN Inhibitor [20]
Gap junction gamma-2 protein (Cx47) TTPOCAL CXG2_HUMAN Inhibitor [21]
Gap junction gamma-3 protein (Cx30.2) TTUW608 CXG3_HUMAN Inhibitor [22]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Alcohol dehydrogenase class-II (ADH4) DEOCWU3 ADH4_HUMAN Substrate [23]
Alcohol dehydrogenase class-I gamma (ADH1C) DEM1HNL ADH1G_HUMAN Substrate [23]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alcohol dehydrogenase class-3 (ADH5) OTSO67MI ADHX_HUMAN Regulation of Drug Effects [24]
Cystic fibrosis transmembrane conductance regulator (CFTR) OT6B22QH CFTR_HUMAN Gene/Protein Processing [25]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Gene/Protein Processing [26]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4278).
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 714).
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 715).
4 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 717).
5 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 723).
6 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 729).
7 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 733).
8 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 734).
9 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 728).
10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 730).
11 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 725).
12 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 726).
13 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 732).
14 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 716).
15 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 720).
16 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 719).
17 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 721).
18 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 724).
19 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 722).
20 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 727).
21 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 731).
22 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 718).
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