Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU83KP)

Drug Name
1-((S)-2-aminopropyl)-1H-indazol-6-ol Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
135453290
CAS Number
CAS 210580-75-9
TTD Drug ID
DMU83KP

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Adrenergic receptor alpha-2C (ADRA2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
MOXONIDINE DMGFB0E Alcohol dependence 6C40.2 Approved [2]
Dihydroergocristine DM5SQ1G Alcohol dependence 6C40.2 Approved [3]
Brimonidine DMQLT4N Ocular hypertension 9C61.01 Approved [4]
Amosulalol DML8QSZ Hypertension BA00-BA04 Approved [5]
Amezinium DM6I2WQ Hypotension BA20-BA21 Approved [6]
Propylhexedrine DMTBW2O Obesity 5B81 Approved [7]
Tetrahydrozoline DMT57WC Ocular disease 1F00.1Z Approved [8]
Rilmenidine DM13PQW Hypertension BA00-BA04 Approved [9]
Xylometazoline DMKV32D Allergic rhinitis CA08.0 Phase 4 [10]
TNX-102 DMO1234 Fibromyalgia MG30.01 Phase 3 [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 1D receptor (HTR1D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [12]
Eletriptan DMW649X Migraine 8A80 Approved [13]
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [13]
Frovatriptan DM7RE8P Migraine 8A80 Approved [13]
Sumatriptan DMVYXR8 Migraine 8A80 Approved [14]
Rizatriptan DMDJMA3 Migraine 8A80 Approved [15]
Almogran DM7I64Z Migraine 8A80 Approved [16]
Neu-P11 DMIQDFW Alzheimer disease 8A20 Phase 2 [17]
FKB01MD DM2O7NM N. A. N. A. Phase 2 [18]
NXN-188 DMMBAIH Migraine 8A80 Phase 2 [19]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Adrenergic receptor alpha-2A (ADRA2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lofexidine DM1WXA6 Heroin and opiate withdrawal 6C43 Approved [20]
MOXONIDINE DMGFB0E Alcohol dependence 6C40.2 Approved [2]
Connexyn DMF29Q5 Attention deficit hyperactivity disorder 6A05.Z Approved [21]
MEDETOMIDINE DMX9Y7V Pain MG30-MG3Z Phase 2 [22]
DSP-1200 DM4WSHG Depression 6A70-6A7Z Phase 1 [18]
MAZAPERTINE DMRHYAU N. A. N. A. Discontinued in Phase 2 [23]
NMI-870 DMU596F Sexual dysfunction HA00-HA01 Discontinued in Phase 2 [24]
SNAP-5089 DMROJEN Heart arrhythmia BC65 Terminated [25]
A-80426 DMBC3DG N. A. N. A. Terminated [26]
WB-4101 DMQU8B1 N. A. N. A. Terminated [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 2B receptor (HTR2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [28]
Triflupromazine DMKFQJP Psychotic disorder 6A20-6A25 Approved [29]
Minaprine DM0EP7M Depression 6A70-6A7Z Approved [30]
SPN-812 DMTV7XH Attention deficit hyperactivity disorder 6A05.Z Phase 4 [31]
Vabicaserin DM9GZW6 Psychotic disorder 6A20-6A25 Phase 2 [32]
PRX-08066 DMR7H2V Pulmonary arterial hypertension BB01.0 Phase 2 [33]
Pyrimidine derivative 29 DMVOYJ8 N. A. N. A. Patented [34]
Pyrimidine derivative 26 DM90WKN N. A. N. A. Patented [34]
Pyrimidine derivative 23 DM5MLQU N. A. N. A. Patented [34]
Pyrimidine derivative 25 DM51MFS N. A. N. A. Patented [34]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 2A receptor (HTR2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [28]
Zotepine DMF3VXA Anxiety disorder 6B00-6B0Z Approved [35]
Iloperidone DM6AUFY Schizophrenia 6A20 Approved [36]
Flibanserin DM70DTN Mood disorder 6A60-6E23 Approved [37]
Lurasidone hydrochloride DMCVPXO Schizophrenia 6A20 Approved [38]
Aniracetam DMOIFW0 Cerebrovascular ischaemia 8B1Z Approved [39]
lumateperone tosylate DMQ8HOJ Schizophrenia 6A20 Approved [40]
Sarpogrelate DMGLP6S Diabetic complication 5A2Y Approved [41]
Pimavanserin DMR7IVC Parkinson disease 8A00.0 Approved [42]
Zicronapine DMP8ESD Schizophrenia 6A20 Phase 3 [43]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 4 receptor (HTR4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisapride DMY7PED Gastroesophageal reflux disease DA22.Z Approved [44]
Tegaserod DM3XYD1 Irritable bowel syndrome DD91.0 Approved [45]
R0-93877 DMM4U9G Constipation DD91.1 Approved [14]
HTF 919 DM78G6F Constipation DD91.1 Approved [46]
Mosapride DM2VOQ3 N. A. N. A. Phase 4 [47]
Renzapride DM7HQNX Irritable bowel syndrome DD91.0 Phase 3 [48]
Lintopride DMSHGWN Nausea MD90 Phase 2 [49]
TD-8954 DM3C9NV Gastrointestinal disease DE2Z Phase 2 [50]
SB-207266A DM27KFY Irritable bowel syndrome DD91.0 Phase 2 [14]
YKP-GI DM740LV Constipation DD91.1 Phase 2 [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 1A receptor (HTR1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Trazodone DMK1GBJ Depression 6A70-6A7Z Approved [13]
Buspirone DMBS632 Anxiety disorder 6B00-6B0Z Approved [52]
OPC-34712 DMHG57U Major depressive disorder 6A70.3 Approved [53]
Vilazodone DM4LECQ Major depressive disorder 6A70.3 Approved [54]
Flibanserin DM70DTN Mood disorder 6A60-6E23 Approved [37]
Tertatolol DM2L3D5 Hypertension BA00-BA04 Approved [55]
Urapidil DMD59GI Hypertension BA00-BA04 Approved [56]
Treximet DMU54QB Migraine 8A80 Approved [57]
CM-2395 DMASPWR Schizophrenia 6A20 Phase 3 [58]
Eltoprazine DMW6C81 Attention deficit hyperactivity disorder 6A05.Z Phase 3 [59]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 2C receptor (HTR2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [28]
Lorcaserin DMG6OYJ Obesity 5B81 Approved [60]
Tramadol DMRQD04 Pain MG30-MG3Z Approved [61]
Mirtazapine DML53ZJ Depression 6A70-6A7Z Approved [62]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [63]
Methysergide DM1EF73 Migraine 8A80 Approved [64]
Eltoprazine DMW6C81 Attention deficit hyperactivity disorder 6A05.Z Phase 3 [59]
M100907 DM7ZFBA Sleep-wake disorder 7A00-7B2Z Phase 3 [65]
SR46349B DM1ODMR Primary insomnia 7A00 Phase 3 [66]
Vabicaserin DM9GZW6 Psychotic disorder 6A20-6A25 Phase 2 [32]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 1A receptor (HTR1A) TTSQIFT 5HT1A_HUMAN Inhibitor [1]
5-HT 1D receptor (HTR1D) TT6MSOK 5HT1D_HUMAN Inhibitor [1]
5-HT 2A receptor (HTR2A) TTJQOD7 5HT2A_HUMAN Inhibitor [1]
5-HT 2B receptor (HTR2B) TT0K1SC 5HT2B_HUMAN Inhibitor [1]
5-HT 2C receptor (HTR2C) TTWJBZ5 5HT2C_HUMAN Inhibitor [1]
5-HT 4 receptor (HTR4) TT07C3Y 5HT4R_HUMAN Inhibitor [1]
Adrenergic receptor alpha-2A (ADRA2A) TTWG9A4 ADA2A_HUMAN Inhibitor [1]
Adrenergic receptor alpha-2C (ADRA2C) TT2NUT5 ADA2C_HUMAN Inhibitor [1]

References

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