General Information of Drug Inactive Ingredient (DIG) (ID: E00369)

DIG Name
Sodium citrate dihydrate
Synonyms
Trisodium citrate dihydrate; Sodium citrate dihydrate; 6132-04-3; Sodium citrate tribasic dihydrate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate; Citric acid trisodium salt dihydrate; MFCD00150031; Sodium citrate hydrate; trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate; UNII-B22547B95K; B22547B95K; trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate; Trisodium citrate dihydrate;Citric acid trisodium salt dihydrate; tri-sodium citrate dihydrate; Citric acid, trisodium salt dihydrate, ACS reagent; sodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate; Sodiumcitrate; Citric acid, trisodium salt dihydrate, 99%, for biochemistry; Natrum citricum; Tricitrasol (TN); ACMC-20ajao; Sodium citrate (TN); C6H9Na3O9; Sodium citrate [USP:JAN]; DTXSID1049437; Sodium citrate hydrate (JP17); CHEBI:32142; Trisodium citrate dihydrate, ACS; AKOS025293920; Citric acid, trisodium salt, dihydrate; Citronensaeure,Trinatrium-Salz-Dihydrat; Sodium citrate dihydrate, >=99%, FG; BP-31019; R385; Citrate, 0.5M buffer solution, pH 3.0; Citrate, 0.5M buffer solution, pH 4.0; Citrate, 0.5M buffer solution, pH 4.5; Citrate, 0.5M buffer solution, pH 5.0; Citrate, 0.5M buffer solution, pH 5.5; Citrate, 0.5M buffer solution, pH 6.0; Sodium citrate tribasic dihydrate, >=98%; Sodium citrate dihydrate, ACS reagent grade; C13249; D01781; Sodium citrate tribasic dihydrate, AR, >=99%; Sodium citrate tribasic dihydrate, LR, >=99%; Citric acid trisodium salt dihydrate ACS reagent; 124799-EP2287158A1; 124799-EP2295426A1; 124799-EP2295427A1; A835986; Citric acid, trisodium salt dihydrate, 99%, pure; Q22075862; Sodium citrate dihydrate Biochemical grade, Fine Granular; Sodium citrate tribasic dihydrate, USP, 99.0-100.5%; Sodium citrate tribasic dihydrate, ACS reagent, >=99.0%; trisodium 2-oxidanylpropane-1,2,3-tricarboxylate dihydrate; UNII-1Q73Q2JULR component NLJMYIDDQXHKNR-UHFFFAOYSA-K; Sodium citrate tribasic dihydrate, BioUltra, >=99.0% (NT); Sodium citrate tribasic dihydrate, insect cell culture tested; Sodium citrate tribasic dihydrate, JIS special grade, >=99.0%; Sodium citrate tribasic dihydrate, p.a., ACS reagent, 99.0%; Sodium citrate tribasic dihydrate, purum p.a., >=99.0% (NT); Sodium citrate tribasic dihydrate, SAJ first grade, >=99.0%; Sodium citrate tribasic dihydrate, tested according to Ph.Eur.; trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2); Trisodium citrate dihydrate, meets USP testing specifications; 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate; Sodium citrate tribasic dihydrate, BioXtra, >=99.0% (titration); Sodium citrate tribasic dihydrate, for molecular biology, >=99%; Sodium citrate tribasic dihydrate, Vetec(TM) reagent grade, 98%; Sodium citrate, United States Pharmacopeia (USP) Reference Standard; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, dihydrate; Sodium citrate tribasic dihydrate, p.a., ACS reagent, reag. ISO, 99-101%; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2); Sodium citrate tribasic dihydrate, BioUltra, for molecular biology, >=99.5% (NT); Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, >=99.0% (NT); Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=99.0%; Sodium Citrate, Pharmaceutical Secondary Standard; Certified Reference Material; Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5%; Sodium citrate tribasic dihydrate, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E331, 99-100.5% (calc. to the dried substance); Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=98% (titration), powder
DIG Function
Alkalizing agent; Buffering agent; Complexing agent; Emulsifying agent
Formula
C6H9Na3O9
Canonical SMILES
C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.O.O.[Na+].[Na+].[Na+]
InChI
1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
InChIKey
NLJMYIDDQXHKNR-UHFFFAOYSA-K
Physicochemical Properties Molecular Weight 294.1 Topological Polar Surface Area 143
XlogP N.A. Complexity 211
Heavy Atom Count 18 Rotatable Bond Count 2
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 9

Full List of Drug(s) Co-administrated with This DIG

22 Approved Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
Allopregnanolone DMNLHAC Depression [6A70-6A7Z] Brexanolone 100 mg/20 ml Injection F23092
Amikacin DM5PDRB Bacteremia [1A73] Amikacin eq 250mg injectable F23623
Amisulpride DMSJVAM Schizophrenia [6A20] Amisulpride 5mg/2ml solution F24176
Aripiprazole DM3NUMH Bipolar I disorder [] Aripiprazole Lauroxil 675mg/2.4ml extended release suspension F23376
Buprenorphine DMPRI8G Opioid dependence [6C43.2Z] Buprenorphine 2 mg tablet F02767
Carbachol DMX9K8F Glaucoma/ocular hypertension [9C61] Carbachol 0.01% solution F23101
Didanosine DMI2QPE Human immunodeficiency virus infection [1C62] Didanosine 200 mg capsule F05860
Dopamine DMPGUCF Acromegaly [5A60.0] Dopamine Hydrochloride 40mg/ml injectable F23434
Fluconazole DMOWZ6B Cryptococcal meningitis [] Fluconazole 100 mg tablet F08322
Isoproterenol DMK7MEY Atrioventricular block [] Isoproterenol 1mg/5ml solution F23794
Larotrectinib DM26CQR Solid tumour/cancer [2A00-2F9Z] Larotrectinib 20 mg/ml solution F24272
Lefamulin DME6G97 Community-acquired pneumonia [CA40.Z] Lefamulin 150 mg Injection F23803
Levetiracetam DMTGDN8 Epilepsy [8A60-8A68] Levetiracetam 750 mg tablet F11588
Meloxicam DM2AR7L Arthritis [FA20] Meloxicam 15 mg tablet F12871
Metformin DM89QE1 Colorectal carcinoma [] Metformin 1000 mg tablet F13120
Nafcillin DMN9RPO Arthritis [FA20] Nafcillin 2g/100ml solution F23830
Oxacillin DMTAFY4 Bacterial infection [1A00-1C4Z] Oxacillin 1g/50ml solution F23852
Oxymetazoline DM8ZXT6 Arrhythmia [BC9Z] Oxymetazoline 1% cream F23856
Phenylephrine DMZHUO5 Allergic rhinitis [CA08.0] Phenylephrine 10 mg tablet F17177
Quetiapine DM1N62C Anorexia nervosa cachexia [6B80] Quetiapine 50 mg tablet F18543
Raltegravir DMYURI6 Human immunodeficiency virus infection [1C62] Raltegravir 100 mg tablet F18691
Zithromax DMN4H2O Syphilis infection [1A6Z] Azithromycin 500 mg tablet F02191
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⏷ Show the Full List of 22 Approved Drug(s)
1 Clinical Trial Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
PHN-131 DM1SV8I Pain [MG30-MG3Z] Nalbuphine Hydrochloride 10mg/ml injectable F23236
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