Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT1RS9F)

• DTT Name: Acetylcholinesterase (AChE) DTT Info
• Gene Name: ACHE

Molecule-Related Drug & Molecule List

15 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ambenonium	DMOP0BL	Myasthenia gravis	8C6Y	Approved	[1]
Demecarium bromide	DMAYEU1	Open-angle glaucoma	9C61	Approved	[2]
Donepezil	DMIYG7Z	Advanced cancer	2A00-2F9Z	Approved	[3]
Echothiophate Iodide	DMSNVGB	Chronic glaucoma	9C61.0Z	Approved	[4]
Edrophonium	DMCRQHB	Myasthenia gravis	8C6Y	Approved	[5]
Galantamine	DMEO794	Alzheimer disease	8A20	Approved	[6]
Huperzine A	DMMAWLU	Alzheimer disease	8A20	Approved	[7]
Isoflurophate	DMBSK7X	Glaucoma/ocular hypertension	9C61	Approved	[8]
Malathion	DMXZ84M	Pediculus capitis infestation	1G00.0	Approved	[9]
Neostigmine	DM6T2J3	Myasthenia gravis	8C6Y	Approved	[5]
Pralidoxime Chloride	DMGQ0ZI	Poisoning due to pesticides and chemicals	NE6Z	Approved	[4]
Pyridostigmine	DM8HO1L	Myasthenia gravis	8C6Y	Approved	[10]
Rivastigmine	DMG629M	Alzheimer disease	8A20	Approved	[3]
Tacrine	DM51FY6	Alzheimer disease	8A20	Approved	[11]
YM443	DMNZCI1	Functional dyspepsia	DD90.3	Approved	[12]

17 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(-)-Phenserine	DMNCY1I	Alzheimer disease	8A20	Phase 3	[13]
Amocarzine	DMB9587	Helminth infection	1F90.0	Phase 3	[14]
Eptastigmine	DMTV7ZM	Cognitive impairment	6D71	Phase 3	[15]
INM-176	DMLG96Z	Alzheimer disease	8A20	Phase 3	[16]
Suronacrine maleate	DMH2FN1	Cognitive impairment	6D71	Phase 3	[17]
AD-35	DMVDQO6	Alzheimer disease	8A20	Phase 2	[18]
Ladostigil	DMJSY3Q	Alzheimer disease	8A20	Phase 2	[19]
Methanesulfonyl fluoride	DMS7FRI	Alzheimer disease	8A20	Phase 2	[20]
R-phenserine	DM4L5VJ	Alzheimer disease	8A20	Phase 2	[21]
T-82	DM4JFMZ	Cognitive impairment	6D71	Phase 2	[22]
CPC-212	DM3J1T9	Alzheimer disease	8A20	Phase 1	[23]
CPC-250	DMDQG4Y	Alzheimer disease	8A20	Phase 1	[23]
Desoxypeganine	DMTR7EH	Alcohol dependence	6C40.2	Phase 1	[24]
GTP-004	DM20HS7	Myasthenia gravis	8C6Y	Phase 1	[23]
KW-5092	DMALK7F	Pain	MG30-MG3Z	Phase 1	[25]
PRX-105	DMWT8RI	Poison intoxication	NE6Z	Phase 1	[26]
ZT-1	DMO2WYX	Parkinson disease	8A00.0	Phase 1	[27]

54 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-PAM derivative 1	DMI4KBC	N. A.	N. A.	Patented	[28]
4-PAM derivative 1	DMN37BI	N. A.	N. A.	Patented	[28]
Amidine oxime derivative 1	DM8STUQ	N. A.	N. A.	Patented	[28]
Decyle nelycorine dibromo salt derivative 1	DMXKUMJ	N. A.	N. A.	Patented	[29]
Di-substituted piperidine derivative 2	DM23XQL	N. A.	N. A.	Patented	[29]
Egonol compound 1	DMQF1UM	N. A.	N. A.	Patented	[28]
Fluorinated donepezil derivative 1	DMQOGHN	N. A.	N. A.	Patented	[28]
Fluorinated donepezil derivative 2	DMV1SCA	N. A.	N. A.	Patented	[28]
Galantamine analog 1	DM5BVCS	N. A.	N. A.	Patented	[28]
Indoline derivative 1	DMJ41UI	N. A.	N. A.	Patented	[29]
Isochroman-4-ketone derivative 1	DMDBK6O	N. A.	N. A.	Patented	[29]
Lycorine dimer salt derivative 1	DMGKQXP	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-12	DMBNHI7	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-13	DMY5UB8	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-14	DMGI5Z8	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-15	DMEW46T	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-27	DMO0QME	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-28	DMVM31E	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-3	DM7JIF0	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-36	DM7CWZ4	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-39	DMQOAJP	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-42	DM68KPS	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-43	DM12X0P	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-47	DMEXATH	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-48	DM81A50	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-49	DMQTRFX	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-51	DMNH891	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-52	DMRH7ZY	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-7	DMAN71J	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-neostenine	DM7TLDW	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-neotuberostemonine	DM3CPJQ	N. A.	N. A.	Patented	[28]
PMID27967267-Compound-stenine	DM2K54D	N. A.	N. A.	Patented	[28]
PMID29757691-Compound-10	DMZBHR9	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-2a	DMEUC04	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-2a-i	DMBRQP1	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-4	DMFD9UZ	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-7	DM7TPBF	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-8a	DM5IFBV	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-8b	DMEOZKF	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-8c	DMHL7SW	N. A.	N. A.	Patented	[29]
PMID29757691-Compound-8d	DM6PDEH	N. A.	N. A.	Patented	[29]
Quinazoline alkaloid derivative 1	DMH86F2	N. A.	N. A.	Patented	[29]
Tacrine heterodimer derivative 1	DMFOKRW	N. A.	N. A.	Patented	[29]
Tacrine-caffeic acid hybrid derivative 1	DMJ04RQ	N. A.	N. A.	Patented	[28]
Tacrine-caffeic acid hybrid derivative 2	DMMVPSY	N. A.	N. A.	Patented	[28]
Tacrine-dihydropyridine hybrid derivative 1	DMK0S4I	N. A.	N. A.	Patented	[28]
Tacrine-indole hybrid derivative 1	DMQ3K5B	N. A.	N. A.	Patented	[28]
Tacrine-indole hybrid derivative 2	DMH9N2T	N. A.	N. A.	Patented	[28]
Tacrine-indole hybrid derivative 3	DMUTKNW	N. A.	N. A.	Patented	[28]
Tacrine-phenothiazine hybrid derivative 1	DMNGY8R	N. A.	N. A.	Patented	[28]
Tetra-hydro-isoquinoline derivative 1	DML86IO	N. A.	N. A.	Patented	[29]
Tetra-hydro-isoquinoline derivative 2	DM5CKVF	N. A.	N. A.	Patented	[29]
Tetra-hydro-isoquinoline derivative 3	DMCZA45	N. A.	N. A.	Patented	[29]
Tetra-hydro-isoquinoline derivative 4	DMDV0MP	N. A.	N. A.	Patented	[29]

20 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
VELNACRINE	DMUB0EC	Cognitive impairment	6D71	Discontinued in Phase 3	[30]
Zanapezil	DMTCP8H	Alzheimer disease	8A20	Discontinued in Phase 3	[31]
Caracemide	DMNOLHT	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[32]
HP-290	DMUMGCY	Parkinson disease	8A00.0	Discontinued in Phase 2	[33]
Icopezil maleate	DM5WUK9	Cognitive impairment	6D71	Discontinued in Phase 2	[34]
Physostigmine	DM2N0TO	Xerostomia	DA02.1	Discontinued in Phase 2	[35]
S-9977	DMEO6A5	Cognitive impairment	6D71	Discontinued in Phase 2	[36]
SM-10888	DMBUH7E	Cognitive impairment	6D71	Discontinued in Phase 2	[37]
TAK-802	DMHNZ31	Urinary dysfunction	GC2Z	Discontinued in Phase 2	[38]
ZIFROSILONE	DMC6H4Y	Cognitive impairment	6D71	Discontinued in Phase 2	[39]
NP-61	DMXI5YW	Alzheimer disease	8A20	Discontinued in Phase 1	[40]
7-methoxytacrine	DMX5K4C	N. A.	N. A.	Terminated	[42]
ABS-301	DMCW5DJ	Alzheimer disease	8A20	Terminated	[43]
CI-1002	DMJ2P1Q	Alzheimer disease	8A20	Terminated	[44]
F-3796	DMXB8SE	Alzheimer disease	8A20	Terminated	[45]
FR-152558	DMOEYX2	Alzheimer disease	8A20	Terminated	[46]
MF-8615	DM47WS2	Alzheimer disease	8A20	Terminated	[47]
MF268	DMHV5OD	Alzheimer disease	8A20	Terminated	[48]
NP-7557	DM4B1VF	Alzheimer disease	8A20	Terminated	[49]
Ro-46-5934	DMU9JAH	Alzheimer disease	8A20	Terminated	[50]

2 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PHENSERINE TARTRATE	DMIGH6W	Parkinson disease	8A00.0	Preclinical	[21]
SPH-1285	DMMA2ZW	Alzheimer disease	8A20	Preclinical	[41]

220 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(-)-huperzine B	DMBO9J3	Discovery agent	N.A.	Investigative	[51]
(-)-Tolserine	DMAT58Z	Discovery agent	N.A.	Investigative	[13]
(1R)-1,2,2-TRIMETHYLPROPYL (S)-METHYLPHOSPHINATE	DMCVKTB	Discovery agent	N.A.	Investigative	[48]
(2-Butyryloxy-ethyl)-trimethyl-ammonium iodide	DMLTMPC	Discovery agent	N.A.	Investigative	[52]
(2-Chloro-ethyl)-trimethyl-ammonium chloride	DM6DH15	Discovery agent	N.A.	Investigative	[52]
(2-Ethoxy-ethyl)-trimethyl-ammonium iodide	DMN7XT9	Discovery agent	N.A.	Investigative	[52]
(2-Mercapto-ethyl)-trimethyl-ammonium iodide	DMCJKOQ	Discovery agent	N.A.	Investigative	[52]
(24S)-ethylcholesta-7,9(11),22(E)-triene-3b-ol	DMPL80G	Discovery agent	N.A.	Investigative	[53]
(3-Bromo-propyl)-trimethyl-ammonium	DMUJ18K	Discovery agent	N.A.	Investigative	[52]
(3-Hydroxy-2-methyl-phenyl)-trimethyl-ammonium	DM08UQF	Discovery agent	N.A.	Investigative	[52]
(3R)-9-amino-3-methyl-1,2,3,4-tetrahydroacridine	DMEUBGY	Discovery agent	N.A.	Investigative	[54]
(4-Bromo-butyl)-trimethyl-ammonium	DMU1HFM	Discovery agent	N.A.	Investigative	[52]
(4-Iodo-butyl)-trimethyl-ammonium iodide	DMOWFE5	Discovery agent	N.A.	Investigative	[52]
(5-Bromo-pentyl)-trimethyl-ammonium	DM4EH2J	Discovery agent	N.A.	Investigative	[52]
(R)-tacrine(10)-hupyridone	DMSFA2D	Discovery agent	N.A.	Investigative	[48]
(RS)-tacrine(10)-hupyridone	DMCN6WR	Discovery agent	N.A.	Investigative	[51]
(S)-tacrine(10)-hupyridone	DMH7QZ2	Discovery agent	N.A.	Investigative	[48]
(S,S)-(-)-bis(10)-hupyridone	DMBR1JS	Discovery agent	N.A.	Investigative	[51]
(S,S)-(-)-bis(12)-hupyridone	DM6PQ8D	Discovery agent	N.A.	Investigative	[51]
1,10-bis(pyridinium)-decane dibromide	DM6VCI3	Discovery agent	N.A.	Investigative	[55]
1,11-bis(pyridinium)-undecane dibromide	DMVXYZL	Discovery agent	N.A.	Investigative	[55]
1,2-Di(berberine-9-O-yl)ethane dibromide	DM7S1D5	Discovery agent	N.A.	Investigative	[56]
1,2-NAPHTHOQUINONE	DMYXELH	Discovery agent	N.A.	Investigative	[57]
1,3-Bis-(3-imidazolidin-2-yl-phenyl)-urea	DM78UPQ	Discovery agent	N.A.	Investigative	[58]
1,3-Di(berberine-9-O-yl)ethane dibromide	DMZKUOX	Discovery agent	N.A.	Investigative	[56]
1,4-Di(berberine-9-O-yl)ethane dibromide	DM87MWN	Discovery agent	N.A.	Investigative	[56]
1,9-bis(pyridinium)-nonane dibromide	DMWC7QE	Discovery agent	N.A.	Investigative	[55]
1-(3-Bromomethyl-phenyl)-2,2,2-trifluoro-ethanone	DM58S47	Discovery agent	N.A.	Investigative	[59]
1-benzene sulfonyl-cis-2,6-dimethyl piperidine	DMQ1EVT	Discovery agent	N.A.	Investigative	[60]
1-Deoxy-1-Thio-Heptaethylene Glycol	DMAEWHB	Discovery agent	N.A.	Investigative	[48]
1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE	DMJBFN0	Discovery agent	N.A.	Investigative	[48]
10-Hydroxy-infractopicrin	DM5H73W	Discovery agent	N.A.	Investigative	[61]
2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-imine	DMYHFUO	Discovery agent	N.A.	Investigative	[62]
2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose	DMOUG6Y	Discovery agent	N.A.	Investigative	[63]
2-(N-Morpholino)-Ethanesulfonic Acid	DMZVHSB	Discovery agent	N.A.	Investigative	[63]
2-Hex-5-enyl-5-non-8-enyl-3,4-dihydro-2H-pyrrole	DMRXW3U	Discovery agent	N.A.	Investigative	[64]
2-Hex-5-enyl-5-non-8-enyl-pyrrolidine	DM7KDQV	Discovery agent	N.A.	Investigative	[64]
2-Hex-5-enyl-5-nonyl-pyrrolidine	DMIBRYM	Discovery agent	N.A.	Investigative	[64]
2-morpholino-N-phenethylpyrimidin-4-amine	DMIQYWM	Discovery agent	N.A.	Investigative	[65]
2-Propyl-beta-carboline-2-ium iodide	DMBW6GA	Discovery agent	N.A.	Investigative	[66]
24-ethyl-cholest-7-ene-3,5,6-triol	DMQSTYZ	Discovery agent	N.A.	Investigative	[53]
24-ethylcholest-6-ene-3,5-diol	DMZIQ56	Discovery agent	N.A.	Investigative	[53]
3,4,5,6-Tetrachloro-[1,2]benzoquinone	DMSV6K5	Discovery agent	N.A.	Investigative	[67]
3,6,9,12,15-Pentaoxaheptadecane	DMY8IOP	Discovery agent	N.A.	Investigative	[48]
3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM	DMBIRC6	Discovery agent	N.A.	Investigative	[48]
3-(2,5-Dioxo-pyrrolidin-1-yl)-benzoic acid	DM6JTNW	Discovery agent	N.A.	Investigative	[68]
3-(2-Diethylamino-acetamino)-rutaecarpine	DM08GRF	Discovery agent	N.A.	Investigative	[69]
3-(2-Diethylamino-propionamino)-rutaecarpine	DM1FOIZ	Discovery agent	N.A.	Investigative	[69]
3-(2-N-Piperidyl-acetamino)-rutaecarpine	DM3BQO0	Discovery agent	N.A.	Investigative	[69]
3-(2-N-Piperidyl-propionamino)-rutaecarpine	DMFEHDY	Discovery agent	N.A.	Investigative	[69]
3-(2-N-Pyrrolyl-acetamino)-rutaecarpine	DMQ0A8W	Discovery agent	N.A.	Investigative	[69]
3-(2-N-Pyrrolyl-propionamino)-rutaecarpine	DM9MRTW	Discovery agent	N.A.	Investigative	[69]
3-(3-Carboxy-propionylamino)-benzoic acid	DMSJGQE	Discovery agent	N.A.	Investigative	[68]
3-(4-Benzoylpiperazine-1-carbonyl)coumarin	DMAT7VN	Discovery agent	N.A.	Investigative	[70]
3-(4-o-Tolylpiperazine-1-carbonyl)coumarin	DMIBAM2	Discovery agent	N.A.	Investigative	[70]
3-(4-Phenylpiperazin-1-carbonyl)coumarin	DMH27E0	Discovery agent	N.A.	Investigative	[70]
3-(dimethylamino)phenyl phenylcarbamate	DMM05G2	Discovery agent	N.A.	Investigative	[13]
3-hydroxy-N,N,N-trimethylbenzenaminium iodide	DMXO98C	Discovery agent	N.A.	Investigative	[71]
3-[(1s)-1-(Dimethylamino)Ethyl]Phenol	DM2KXFS	Discovery agent	N.A.	Investigative	[48]
3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-1H-indazole	DME1UNY	Discovery agent	N.A.	Investigative	[34]
3-[3-(benzylmethylamino)propoxy]xanthen-9-one	DMPVXTB	Discovery agent	N.A.	Investigative	[72]
3-[4-(benzylmethylamino)butoxy]xanthen-9-one	DMZPULH	Discovery agent	N.A.	Investigative	[72]
3-[5-(benzylmethylamino)pentyloxy]xanthen-9-one	DMQZ0A7	Discovery agent	N.A.	Investigative	[72]
3-[6-(benzylmethylamino)hexyloxy]xanthen-9-one	DM89RN3	Discovery agent	N.A.	Investigative	[72]
3-[7-(benzylmethylamino)-heptyloxy]xanthen-9-one	DMMD3G6	Discovery agent	N.A.	Investigative	[72]
3-[8-(benzylmethylamino)octyloxy]xanthen-9-one	DM31WYF	Discovery agent	N.A.	Investigative	[72]
4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one	DMM9X0G	Discovery agent	N.A.	Investigative	[73]
4-formylphenyl-O-beta-D-ribopyranoside	DM7DW0G	Discovery agent	N.A.	Investigative	[74]
4-formylphenyl-O-beta-Dglucopyranoside	DM1VNEF	Discovery agent	N.A.	Investigative	[74]
4-ISOPROPYLPHENSERINE	DMMDGR2	Discovery agent	N.A.	Investigative	[75]
4-[4-(benzhydryloxy)piperidino]butyl benzoate	DM5Z64L	Discovery agent	N.A.	Investigative	[76]
4ALPHA-(HYDROXYMETHYL)-4ALPHA-DEMETHYLTERRITREM B	DMGYK25	Discovery agent	N.A.	Investigative	[77]
5,6-dinitroacenaphthoquinone	DM07HYA	Discovery agent	N.A.	Investigative	[57]
5-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine	DMTJNY0	Discovery agent	N.A.	Investigative	[78]
5-Hex-5-enyl-2-nonyl-3,4-dihydro-2H-pyrrole	DMHGQRF	Discovery agent	N.A.	Investigative	[64]
6,8-Dichloro-1,2,3,4-tetrahydro-acridin-9-ylamine	DMUEFDM	Discovery agent	N.A.	Investigative	[79]
6-chlorotacrine hydrochloride	DMV0C69	Discovery agent	N.A.	Investigative	[80]
6-hydroxy-1,2,9-trimethyl-9H-beta-carbolin-2-ium	DMWLN2Y	Discovery agent	N.A.	Investigative	[81]
6-hydroxy-1,2-dimethyl-9H-beta-carbolin-2-ium	DM20DAG	Discovery agent	N.A.	Investigative	[81]
6-hydroxy-2,9-dimethyl-9H-beta-carbolin-2-ium	DMNA2M6	Discovery agent	N.A.	Investigative	[81]
6-hydroxy-2-methyl-9H-beta-carbolin-2-ium	DMAK35M	Discovery agent	N.A.	Investigative	[81]
6-methoxy-1,2-dimethyl-9H-beta-carbolin-2-ium	DMJUT70	Discovery agent	N.A.	Investigative	[81]
6-methoxy-1,9-dimethyl-9H-pyrido[3,4-b]indole	DMOHWPD	Discovery agent	N.A.	Investigative	[81]
6-methoxy-2,9-dimethyl-9H-beta-carbolin-2-ium	DMG3F7D	Discovery agent	N.A.	Investigative	[81]
6-methoxy-2-methyl-9H-beta-carbolin-2-ium	DMHITF8	Discovery agent	N.A.	Investigative	[81]
6-Methyl-4-(4-benzoylpiperazin-1-yl)coumarin	DMOVUP2	Discovery agent	N.A.	Investigative	[70]
6-Methyl-4-(4-o-tolylpiperazin-1-yl)coumarin	DMN0SYW	Discovery agent	N.A.	Investigative	[70]
6-Methyl-4-(4-phenylpiperazin-1-yl)coumarin	DMU7E3O	Discovery agent	N.A.	Investigative	[70]
7-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine	DM1SEXA	Discovery agent	N.A.	Investigative	[78]
7-Oxo-7H-dibenzo[de,g]quinoline	DMJZR0A	Discovery agent	N.A.	Investigative	[82]
8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine	DMS7DA3	Discovery agent	N.A.	Investigative	[78]
9-Amino-1,2,3,4-tetrahydro-acridine-1,7-diol	DMNHZFG	Discovery agent	N.A.	Investigative	[30]
9-amino-7H-dibenzo[de,h]quinolin-7-one	DMNMVCZ	Discovery agent	N.A.	Investigative	[82]
9-Ethyl-2-methyl-beta-carboline-2-ium iodide	DM70MPJ	Discovery agent	N.A.	Investigative	[66]
9-Ethyl-beta-carboline	DMHKUO9	Discovery agent	N.A.	Investigative	[66]
9-hydrazino-1,2,3,4-tetrahydroacridine	DMOX21P	Discovery agent	N.A.	Investigative	[83]
9-O-[2-(Phenylol-1-yloxy)ethyl]berberine bromide	DMYXEJ8	Discovery agent	N.A.	Investigative	[84]
9-O-[2-(Phenylol-1-yloxy)hexyl]berberine bromide	DM081G2	Discovery agent	N.A.	Investigative	[84]
9-O-[3-(2-Pyridinoxyl)butyl]-berberine bromide	DMHRV2A	Discovery agent	N.A.	Investigative	[56]
9-O-[3-(4-Bromo-phenoxyl)butyl]-berberine bromide	DM4JG9S	Discovery agent	N.A.	Investigative	[56]
9-O-[3-(4-Nitro-phenoxyl)butyl]-berberine bromide	DMWVSPH	Discovery agent	N.A.	Investigative	[56]
9-O-[3-(Phenylamino)propyl]-berberine bromide	DMKPUWX	Discovery agent	N.A.	Investigative	[56]
9-O-[3-(Phenylol-1-yloxy)propyl]berberine bromide	DM0FNUX	Discovery agent	N.A.	Investigative	[84]
9-O-[4-(Phenylol-1-yloxy)butyl]berberine bromide	DM58XF6	Discovery agent	N.A.	Investigative	[84]
9-O-[5-(Phenylol-1-yloxy)pentyl]berberine bromide	DMPZTG9	Discovery agent	N.A.	Investigative	[84]
Allyl-trimethyl-ammonium	DM1VHCL	Discovery agent	N.A.	Investigative	[52]
AP-2238	DMQWIEL	Discovery agent	N.A.	Investigative	[85]
AP-2243	DMRYL9X	Discovery agent	N.A.	Investigative	[86]
BENZOQUINONE	DMNBA0G	Discovery agent	N.A.	Investigative	[67]
Beta-L-fucose	DM3BOQA	Discovery agent	N.A.	Investigative	[87]
BIS(12)-HUPERZINE B	DMWAS4Q	Discovery agent	N.A.	Investigative	[88]
Bis(14)-Huperzine B	DM58YDV	Discovery agent	N.A.	Investigative	[88]
BIS(16)-HUPERZINE B	DMYQM3B	Discovery agent	N.A.	Investigative	[88]
BIS(18)-HUPERZINE B	DM3W1T4	Discovery agent	N.A.	Investigative	[88]
BIS(20)-HUPERZINE B	DMHQKCJ	Discovery agent	N.A.	Investigative	[88]
BIS(8)-HUPERZINE B	DMER5GT	Discovery agent	N.A.	Investigative	[88]
BIS(9)-HUPERZINE B	DM5WFQM	Discovery agent	N.A.	Investigative	[88]
Bis-7-tacrine	DMVNC1R	Discovery agent	N.A.	Investigative	[65]
But-3-enyl-trimethyl-ammonium bromide	DMMHGIN	Discovery agent	N.A.	Investigative	[52]
BW284C51	DMQ3AC0	Discovery agent	N.A.	Investigative	[89]
BZYX	DMA0GSY	Neurodegenerative disorder	8A20-8A23	Investigative	[3]
CAPROCTAMINE	DMDZE8N	Discovery agent	N.A.	Investigative	[90]
Carinatumins B (2)	DMUSGYQ	Discovery agent	N.A.	Investigative	[91]
CHF-2819	DMLJGVX	Discovery agent	N.A.	Investigative	[92]
CHLORANIL	DMCHGF1	Discovery agent	N.A.	Investigative	[67]
Chlorphrifos oxon	DMGBT68	Discovery agent	N.A.	Investigative	[93]
CHLORPYRIFOS	DMKPUI6	Discovery agent	N.A.	Investigative	[94]
CHOLINE IODIDE	DMW6U7K	Discovery agent	N.A.	Investigative	[52]
Cis-2,6-dimethyl-1-methyl sulfonyl piperidine	DMJ3HG9	Discovery agent	N.A.	Investigative	[60]
CLEBOPRIDE	DMTLOU6	Discovery agent	N.A.	Investigative	[58]
CORONARIDINE	DMZBUE7	Discovery agent	N.A.	Investigative	[95]
CP-126998	DM3ZIDT	Discovery agent	N.A.	Investigative	[96]
CRYPTADINE B	DM92IK8	Discovery agent	N.A.	Investigative	[97]
DECIDIUM	DM4SWYX	Discovery agent	N.A.	Investigative	[51]
Dimethyl-pent-4-enyl-ammonium bromide	DMO0UI8	Discovery agent	N.A.	Investigative	[52]
Ethyl octylfluorophosphonate	DMXMRK7	Discovery agent	N.A.	Investigative	[93]
ETHYLPHENSERINE	DMT51QD	Discovery agent	N.A.	Investigative	[98]
Fucose	DMAHMSV	N. A.	N. A.	Investigative	[63]
Galanthamine derivative	DMAFE24	Discovery agent	N.A.	Investigative	[51]
GANSTIGMINE	DMFT4GU	Discovery agent	N.A.	Investigative	[51]
GENESERINE	DMAUFLQ	Discovery agent	N.A.	Investigative	[92]
HALOXYSTEROL A	DM4AEGQ	Discovery agent	N.A.	Investigative	[53]
HALOXYSTEROL B	DMD8O7S	Discovery agent	N.A.	Investigative	[53]
Haloxysterol C	DMU1DHM	Discovery agent	N.A.	Investigative	[53]
Haloxysterol D	DMWCZLT	Discovery agent	N.A.	Investigative	[53]
Hexyl-trimethyl-ammonium	DM9EW7V	Discovery agent	N.A.	Investigative	[52]
Huprine X	DMTPXB6	Discovery agent	N.A.	Investigative	[51]
Huprine Y	DMYH0XQ	N. A.	N. A.	Investigative	[99]
Huprine-Tacrine Heterodimer	DMJ4ME7	Discovery agent	N.A.	Investigative	[100]
Infractopicrin	DMV6UJ5	Discovery agent	N.A.	Investigative	[61]
Iso-OMPA	DMFX16H	Discovery agent	N.A.	Investigative	[101]
Isopropyl dodecylfluorophosphonate	DML54EA	Discovery agent	N.A.	Investigative	[93]
Isosorbide-2-(methylcarbamate)-5-benzoate	DMC7MLN	Discovery agent	N.A.	Investigative	[101]
Isosorbide-2-(methylcarbamate)-5-mononitrate	DMEKMOF	Discovery agent	N.A.	Investigative	[101]
Isosorbide-2-benzylcarbamate-5-cyclopentanoate	DMWDQ90	Discovery agent	N.A.	Investigative	[101]
Isosorbide-2-benzylcarbamate-5-cyclopropanoate	DM8E2L6	Discovery agent	N.A.	Investigative	[101]
Isosorbide-2-benzylcarbamate-5-tosylate	DMCHSWQ	Discovery agent	N.A.	Investigative	[101]
Isosorbide-di-(4-nitrophenyl carbamate)	DMPA2ON	Discovery agent	N.A.	Investigative	[102]
Isosorbide-di-(benzylcarbamate)	DMFVN71	Discovery agent	N.A.	Investigative	[102]
Isosorbide-di-(ethylcarbamate)	DMTHWXO	Discovery agent	N.A.	Investigative	[102]
Isosorbide-di-phenylcarbamate	DMT1ZGM	Discovery agent	N.A.	Investigative	[102]
LAWSARITOL	DM5GNFO	Discovery agent	N.A.	Investigative	[53]
LIPOCRINE	DMUIVCX	Discovery agent	N.A.	Investigative	[103]
LYSICAMINE	DMIZQW6	Discovery agent	N.A.	Investigative	[104]
MEMOQUIN	DM9S30P	Discovery agent	N.A.	Investigative	[103]
MESUAGENIN A	DMZ12GE	Discovery agent	N.A.	Investigative	[105]
MESUAGENIN B	DMKXG3V	Discovery agent	N.A.	Investigative	[105]
Mesuagenin D	DMLZGO7	Discovery agent	N.A.	Investigative	[105]
Methyl Phosphinic Acid	DM096SI	Discovery agent	N.A.	Investigative	[63]
MMB-4	DMUL4PE	Poison intoxication	NE6Z	Investigative	[3]
Monoisopropylphosphorylserine	DM0OFT6	Discovery agent	N.A.	Investigative	[63]
N,N'-(1',10'-decylene)-bis-(-)-nor-MEP	DMIX0CT	Discovery agent	N.A.	Investigative	[106]
N,N'-(1',11'-undecydene)-bis-(-)-nor-MEP	DM5NVIO	Discovery agent	N.A.	Investigative	[106]
N,N'-(1',12'-dodecydene)-bis-(-)-nor-MEP	DMWI06H	Discovery agent	N.A.	Investigative	[106]
N,N'-(1',5'-pentylene)-bis-(-)-nor-MEP	DMBPC0K	Discovery agent	N.A.	Investigative	[106]
N,N'-(1',6-hexylene)-bis-(-)-nor-MEP	DMU4BIW	Discovery agent	N.A.	Investigative	[106]
N,N'-(1',7'-heptylene)-bis-(-)-nor-MEP	DMSORHA	Discovery agent	N.A.	Investigative	[106]
N,N'-(1',8'-octylene)-bis-(-)-nor-MEP	DMHFYK2	Discovery agent	N.A.	Investigative	[106]
N,N'-(1',9'-nonylene)-bis-(-)-nor-MEP	DMIWF7U	Discovery agent	N.A.	Investigative	[106]
N-(14-methylallyl)norgalanthamine	DMW460V	Discovery agent	N.A.	Investigative	[107]
N-ALLYLNORGALANTHAMINE	DMRXA8N	Discovery agent	N.A.	Investigative	[107]
N-allylnorlitebamine	DM5W2VK	Discovery agent	N.A.	Investigative	[108]
N-benzyl-2-(pyrrolidin-1-yl)pyrimidin-4-amine	DM0ZXBQ	Discovery agent	N.A.	Investigative	[65]
N-benzyl-2-morpholinopyrimidin-4-amine	DMQCGFL	Discovery agent	N.A.	Investigative	[65]
N-benzyl-2-thiomorpholinopyrimidin-4-amine	DMRJMGK	Discovery agent	N.A.	Investigative	[65]
N-benzylnorlitebamine	DMVEZH1	Discovery agent	N.A.	Investigative	[108]
N-butylnorlitebamine	DMNFTO6	Discovery agent	N.A.	Investigative	[108]
N-isobutylnorlitebamine	DM9Z6VP	Discovery agent	N.A.	Investigative	[108]
N-isopropylnorlitebamine	DMG8NB0	Discovery agent	N.A.	Investigative	[108]
N-isopropylnorlitebamineN-methoiodide	DMDVO9T	Discovery agent	N.A.	Investigative	[108]
N-Methyl-1'H-phenothiazine-1'-carboxamide	DMK8VZM	Discovery agent	N.A.	Investigative	[109]
N-n-dodecyl-7-methoxytacrine hydrochloride	DM8FOSR	Discovery agent	N.A.	Investigative	[42]
N-n-heptyl-7-methoxytacrine hydrochloride	DMA8R47	Discovery agent	N.A.	Investigative	[42]
N-n-hexyl-7-methoxytacrine hydrochloride	DM4ZMG6	Discovery agent	N.A.	Investigative	[42]
N-n-nonyl-7-methoxytacrine hydrochloride	DMLH23M	Discovery agent	N.A.	Investigative	[42]
N-n-octyl-7-methoxytacrine hydrochloride	DMLC257	Discovery agent	N.A.	Investigative	[42]
N-n-pentyl-7-methoxytacrine hydrochloride	DMWAK5V	Discovery agent	N.A.	Investigative	[42]
N-n-propyl-7-methoxytacrine hydrochloride	DMCN78A	Discovery agent	N.A.	Investigative	[42]
N-phenethyl-2-(pyrrolidin-1-yl)pyrimidin-4-amine	DMJQZMH	Discovery agent	N.A.	Investigative	[65]
N-propylnorlitebamine	DM3JQYD	Discovery agent	N.A.	Investigative	[108]
NPRx-30	DMYB2EZ	Neurodegenerative disorder	8A20-8A23	Investigative	[3]
NSC-23180	DMJ91Y7	Discovery agent	N.A.	Investigative	[57]
OBIDOXIME	DMM98BC	Discovery agent	N.A.	Investigative	[94]
PARAOXON	DMN4ZKC	Discovery agent	N.A.	Investigative	[93]
Petrosamine	DMYIEOJ	Discovery agent	N.A.	Investigative	[110]
Propidium	DMZ1FRS	Discovery agent	N.A.	Investigative	[63]
Pseudocolumbamine trifluoroacetate	DM0E5G9	Discovery agent	N.A.	Investigative	[104]
Pseudopalmatine trifluoroacetate	DM4HE1V	Discovery agent	N.A.	Investigative	[104]
TACRINE(8)-4-AMINOQUINOLINE	DMOWHER	Discovery agent	N.A.	Investigative	[48]
TASPINE	DM9S5DV	Discovery agent	N.A.	Investigative	[111]
TERRITREM B	DMPX7QS	Discovery agent	N.A.	Investigative	[112]
Tetraethylene Glycol	DMH4AGL	Discovery agent	N.A.	Investigative	[63]
THIOCTIC ACID	DMNFCXW	Discovery agent	N.A.	Investigative	[113]
TOLSERINE	DMPTM6V	Discovery agent	N.A.	Investigative	[98]
TRIMEDOXIME	DMPXHTY	Discovery agent	N.A.	Investigative	[94]
Trimethyl-(3-nitro-phenyl)-ammonium iodide	DMQXPMB	Discovery agent	N.A.	Investigative	[52]
Trimethyl-(4-oxo-pentyl)-ammonium iodide	DMJ4I98	Discovery agent	N.A.	Investigative	[52]
TURBINATINE	DMLDYVB	Discovery agent	N.A.	Investigative	[114]
Voacangine	DMA106W	Discovery agent	N.A.	Investigative	[95]
XANTHOSTIGMINE	DM38TLN	Discovery agent	N.A.	Investigative	[115]

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