Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT3ROYC)

• DTT Name: Serotonin transporter (SERT) DTT Info
• Gene Name: SLC6A4

Molecule-Related Drug & Molecule List

26 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[1]
Amfepramone	DM9YSNQ	Migraine	8A80	Approved	[2]
Amitriptyline	DMK7F9S	Depression	6A70-6A7Z	Approved	[3]
Bupropion	DM5PCS7	Depression	6A70-6A7Z	Approved	[4]
Chlorphentermine Hydrochloride	DMQRPOS	Appetite suppressant	MG43	Approved	[5]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[6]
Clomipramine	DMINRKW	Depression	6A70-6A7Z	Approved	[7]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[8]
Dasotraline	DMLDQFV	Attention deficit hyperactivity disorder	6A05.Z	Approved	[9]
Desvenlafaxine	DMHD4PE	Major depressive disorder	6A70.3	Approved	[10]
Dextromethorphan Polistirex	DMEHCY5	Dry cough	MD12	Approved	[6]
Duloxetine	DM9BI7M	Depression	6A70-6A7Z	Approved	[11]
Escitalopram	DMFK9HG	Major depressive disorder	6A70.3	Approved	[12]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[6]
Fluvoxamine	DMQTJSX	Depression	6A70-6A7Z	Approved	[13]
Levomilnacipran	DMV26S8	Fibromyalgia	MG30.01	Approved	[14]
Luvox	DMJKROX	Anxiety disorder	6B00-6B0Z	Approved	[15]
Nortriptyline	DM4KDYJ	Depression	6A70-6A7Z	Approved	[6]
Paroxetine	DM5PVQE	Anxiety disorder	6B00-6B0Z	Approved	[6]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[16]
Sibutramine	DMFJTDI	Obesity	5B81	Approved	[6]
Tianeptine	DMYN8MA	Major depressive disorder	6A70.3	Approved	[17]
Trazodone	DMK1GBJ	Depression	6A70-6A7Z	Approved	[6]
Venlafaxine	DMR6QH0	Anxiety disorder	6B00-6B0Z	Approved	[4]
Vilazodone	DM4LECQ	Major depressive disorder	6A70.3	Approved	[18]
Vortioxetine	DM6F1PU	Major depressive disorder	6A70.3	Approved	[19]

17 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Amitifadine	DMS1X67	Obesity	5B81	Phase 3	[20]
AVP-786	DMV1SOR	Alzheimer disease	8A20	Phase 3	[21]
Bicifadine	DM42GP9	Chronic low back pain	MG30.02	Phase 3	[22]
ITI-007	DMUQ1DO	Depression	6A70-6A7Z	Phase 3	[23]
LITOXETINE	DMKZRBP	Mood disorder	6A60-6E23	Phase 3	[24]
Brasofensine	DM3TRF7	Parkinson disease	8A00.0	Phase 2	[25]
CLR-3001	DM3Z6IQ	Major depressive disorder	6A70.3	Phase 2	[26]
DA-8031	DMP6MH9	Premature ejaculation	HA03.0Z	Phase 2	[27]
Lu-AA34893	DM2ZUXK	Anxiety disorder	6B00-6B0Z	Phase 2	[28]
MIN-117	DMSLIW6	Major depressive disorder	6A70.3	Phase 2	[29]
NS 2359	DMI5HFU	Cocaine addiction	6C45.2	Phase 2	[30]
TD-9855	DMQD5NA	Pain	MG30-MG3Z	Phase 2	[31]
AD-337	DM8VQ1S	Chemotherapy-induced nausea	MD90	Phase 1	[15]
BGC-20-1259	DMED4AJ	Parkinson disease	8A00.0	Phase 1	[32]
BL-1021	DMAYSFK	Pain	MG30-MG3Z	Phase 1	[33]
GSK-1360707	DMZC9XU	Major depressive disorder	6A70.3	Phase 1	[34]
SEP-228432	DMF89ZT	Depression	6A70-6A7Z	Phase 1	[35]

3 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Citalopram derivative 1	DMITX1G	N. A.	N. A.	Patented	[36]
Piperidine derivative 1	DMHN5KW	N. A.	N. A.	Patented	[36]
PMID29334795-Compound-61	DM9H3LI	N. A.	N. A.	Patented	[36]

15 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dexfenfluramine	DMJ7YDS	Obesity	5B81	Withdrawn from market	[37]
ZIMELIDINE	DMNI3U2	Depression	6A70-6A7Z	Withdrawn from market	[38]
DOV-216303	DMTE14H	Mood disorder	6A60-6E23	Discontinued in Phase 2	[30]
NS-2389	DMVRJ8D	Major depressive disorder	6A70.3	Discontinued in Phase 2	[39]
OxycoDex	DMHFOIX	Pain	MG30-MG3Z	Discontinued in Phase 2	[21]
R-sibutramine metabolite	DMPAH74	Attention deficit hyperactivity disorder	6A05.Z	Discontinued in Phase 2	[40]
SPD-473	DMTJNRL	Mood disorder	6A60-6E23	Discontinued in Phase 2	[41]
YM-992	DM845NM	Depression	6A70-6A7Z	Discontinued in Phase 2	[42]
NSD-644	DMNL9DS	Neurological disorder	6B60	Discontinued in Phase 1	[43]
RG-7166	DMKLPMW	Major depressive disorder	6A70.3	Discontinued in Phase 1	[44]
6-nitroquipazine	DM5MVF9	N. A.	N. A.	Terminated	[45]
A-80426	DMBC3DG	N. A.	N. A.	Terminated	[46]
HydrocoDex	DM4HA9C	Pain	MG30-MG3Z	Terminated	[21]
Irindalone	DMJ3ZUN	Inflammation	1A00-CA43.1	Terminated	[47]
MOXIFETIN HYDROGEN MALEATE	DMO2S6T	Mood disorder	6A60-6E23	Terminated	[48]

232 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
((3R,4R)-4-(o-tolyloxy)chroman-3-yl)methanamine	DM2TIU3	Discovery agent	N.A.	Investigative	[49]
(+/-)-3-((naphthalen-2-yloxy)methyl)pyrrolidine	DML68KX	Discovery agent	N.A.	Investigative	[50]
(+/-)-nantenine	DM0L3GE	Discovery agent	N.A.	Investigative	[51]
(2R,3R)-iodoreboxetine	DMYRHFI	Discovery agent	N.A.	Investigative	[52]
(2R,3S)-2-[(2-Iodophenoxy)phenylmethyl]morpholine	DMY2FX8	Discovery agent	N.A.	Investigative	[53]
(2R,3S)-2-[(3-Iodophenoxy)phenylmethyl]morpholine	DM260TI	Discovery agent	N.A.	Investigative	[53]
(2R,3S)-2-[(4-Iodophenoxy)phenylmethyl]morpholine	DMKM8E2	Discovery agent	N.A.	Investigative	[53]
(2S,3S)-iodoreboxetine	DMBEOIQ	Discovery agent	N.A.	Investigative	[52]
(cis)-1,6-diphenyl-3-aza-bicyclo[3.1.0]hexane	DMMC139	Discovery agent	N.A.	Investigative	[54]
(R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol	DM74IWX	Discovery agent	N.A.	Investigative	[55]
(R)-3-(naphthalen-2-ylmethoxy)pyrrolidine	DM94B12	Discovery agent	N.A.	Investigative	[50]
(R)-6-(pyrrolidin-3-ylmethoxy)-2-naphthonitrile	DM134UV	Discovery agent	N.A.	Investigative	[50]
(R)-DULOXETINE	DMECK7H	Discovery agent	N.A.	Investigative	[56]
(R)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide	DMJFH97	Discovery agent	N.A.	Investigative	[57]
(R)-N-isopropyl-N-(pyrrolidin-3-yl)-2-naphthamide	DMQIUOB	Discovery agent	N.A.	Investigative	[57]
(R)-Norfluoxetine	DMS30KU	Discovery agent	N.A.	Investigative	[58]
(S)-3-(naphthalen-2-ylmethoxy)pyrrolidine	DM5ILK1	Discovery agent	N.A.	Investigative	[50]
(S)-6-(pyrrolidin-3-ylmethoxy)-2-naphthonitrile	DM32PJ5	Discovery agent	N.A.	Investigative	[50]
(S)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide	DMUAYZJ	Discovery agent	N.A.	Investigative	[57]
(S)-NORDULOXETINE	DMULFYA	Discovery agent	N.A.	Investigative	[59]
(S)-Norfluoxetine	DM8ZTPF	Discovery agent	N.A.	Investigative	[58]
1-(1,2-diphenylethyl)piperazine	DM0ARKB	Discovery agent	N.A.	Investigative	[60]
1-(1,3-diphenylpropyl)piperazine	DMTC98X	Discovery agent	N.A.	Investigative	[61]
1-(1,4-diphenylbutan-2-yl)piperazine	DM8Z1QU	Discovery agent	N.A.	Investigative	[61]
1-(1-(2-FLUOROPHENYL)-2-(2-(TRIFLUOROMETHOXY)PHENYL)ETHYL)PIPERAZINE (ENANTIOMERIC MIX)	DMCSOAV	Discovery agent	N.A.	Investigative	[55]
1-(1-(4-FLUOROPHENYL)-2-(2-(TRIFLUOROMETHOXY)PHENYL)ETHYL)PIPERAZINE (ENANTIOMERIC MIX)	DMS9PZ7	Discovery agent	N.A.	Investigative	[55]
1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine	DM54ZKU	Discovery agent	N.A.	Investigative	[55]
1-(1-phenyl-2-(pyridin-2-yl)ethyl)piperazine	DMIZBP6	Discovery agent	N.A.	Investigative	[61]
1-(1-phenyl-2-(pyridin-4-yl)ethyl)piperazine	DMTVPZC	Discovery agent	N.A.	Investigative	[61]
1-(1-phenyl-2-o-tolylethyl)piperazine	DMZ6QX0	Discovery agent	N.A.	Investigative	[60]
1-(2-((3-fluorophenoxy)methyl)phenyl)piperazine	DMJXKOF	Discovery agent	N.A.	Investigative	[62]
1-(2-(2-(DIFLUOROMETHOXY)PHENYL)-1-PHENYLETHYL)PIPERAZINE (ENANTIOMERIC MIX)	DMUJ2WB	Discovery agent	N.A.	Investigative	[55]
1-(2-(2-bromophenyl)-1-phenylethyl)piperazine	DMPRALC	Discovery agent	N.A.	Investigative	[60]
1-(2-(2-chlorophenyl)-1-phenylethyl)piperazine	DMUM4YQ	Discovery agent	N.A.	Investigative	[60]
1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine	DMBRS3D	Discovery agent	N.A.	Investigative	[60]
1-(2-(2-ethylphenyl)-1-phenylethyl)piperazine	DMKWRCD	Discovery agent	N.A.	Investigative	[60]
1-(2-(2-fluorobenzyloxy)phenyl)piperazine	DM6XCPV	Discovery agent	N.A.	Investigative	[62]
1-(2-(2-methoxyphenyl)-1-phenylethyl)piperazine	DM2H38V	Discovery agent	N.A.	Investigative	[55]
1-(2-(3-chlorophenyl)-1-phenylethyl)piperazine	DM4WEGM	Discovery agent	N.A.	Investigative	[60]
1-(2-(3-fluorophenoxy)phenyl)piperazine	DMXV2KQ	Discovery agent	N.A.	Investigative	[62]
1-(2-(3-methoxyphenyl)-1-phenylethyl)piperazine	DM8V5IH	Discovery agent	N.A.	Investigative	[60]
1-(2-(4-fluorophenoxy)phenyl)piperazine	DMU082P	Discovery agent	N.A.	Investigative	[62]
1-(2-(6-fluoronaphthalen-2-yl)ethyl)piperazine	DMR4DJ1	Discovery agent	N.A.	Investigative	[50]
1-(2-(benzyloxy)phenyl)piperazine	DM0UZHL	Discovery agent	N.A.	Investigative	[62]
1-(2-(naphthalen-1-yl)-1-phenylethyl)piperazine	DMXL7Z5	Discovery agent	N.A.	Investigative	[61]
1-(2-(naphthalen-2-yl)-1-phenylethyl)piperazine	DMTEBP0	Discovery agent	N.A.	Investigative	[61]
1-(2-(naphthalen-2-yl)ethyl)piperazine	DMS7YF6	Discovery agent	N.A.	Investigative	[50]
1-(2-(phenoxymethyl)phenyl)piperazine	DM7Z19T	Discovery agent	N.A.	Investigative	[62]
1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one	DMBWCOZ	Discovery agent	N.A.	Investigative	[63]
1-(2-phenoxyphenyl)piperazine	DMWFCYN	Discovery agent	N.A.	Investigative	[62]
1-(3,4-Dichloro-phenyl)-3-diethylamino-indan-5-ol	DMN4JU0	Discovery agent	N.A.	Investigative	[64]
1-(3,4-Dichloro-phenyl)-3-methylamino-indan-5-ol	DMWIEDN	Discovery agent	N.A.	Investigative	[64]
1-(3-chlorophenyl)-2-(piperidin-1-yl)propan-1-one	DMPOVUY	Discovery agent	N.A.	Investigative	[65]
1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one	DMPEZ1V	Discovery agent	N.A.	Investigative	[63]
1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one	DMB9T6F	Discovery agent	N.A.	Investigative	[63]
1-(4-Benzylsulfanyl-phenyl)-propylamine	DMXV9S7	Discovery agent	N.A.	Investigative	[66]
1-(4-bromophenyl)-2-(tert-butylamino)propan-1-one	DMW6YDK	Discovery agent	N.A.	Investigative	[67]
1-(4-bromophenyl)-2-pyrrolidin-1-yl-pentan-1-one	DMPLEC0	Discovery agent	N.A.	Investigative	[63]
1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one	DMBV8PT	Discovery agent	N.A.	Investigative	[63]
1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one	DME435S	Discovery agent	N.A.	Investigative	[63]
1-(benzofuran-2-yl)-3-aza-bicyclo[3.1.0]hexane	DMGNL2A	Discovery agent	N.A.	Investigative	[54]
1-(naphthalen-2-yl)-3-aza-bicyclo[3.1.0]hexane	DMUEQC8	Discovery agent	N.A.	Investigative	[54]
1-(thiophen-2-yl)-3-aza-bicyclo[3.1.0]hexane	DM6J1AK	Discovery agent	N.A.	Investigative	[54]
1-benzylpiperidine hydrochloride	DM7GDEK	Discovery agent	N.A.	Investigative	[68]
1-Biphenyl-4-yl-3-aza-bicyclo[3.1.0]hexane	DM6E7TA	Discovery agent	N.A.	Investigative	[54]
1-fluoro-5-phenyl-3-aza-bicyclo[3.1.0]hexane	DM0Q46C	Discovery agent	N.A.	Investigative	[54]
1-Methyl-2-(4-phenylsulfanyl-phenyl)-ethylamine	DMYU348	Discovery agent	N.A.	Investigative	[66]
1-Methyl-4-p-tolyl-piperidine-4-carbonitrile	DM6XFMT	Discovery agent	N.A.	Investigative	[69]
1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one	DMU04ZQ	Discovery agent	N.A.	Investigative	[63]
1-phenyl-3-aza-bicyclo[3.1.0]hexane	DMUA72F	Discovery agent	N.A.	Investigative	[54]
10R-hydroxylobel-7-ene	DM8XRCT	Discovery agent	N.A.	Investigative	[70]
10R-hydroxylobelane	DMN93QT	Discovery agent	N.A.	Investigative	[70]
10S-hydroxylobel-7-ene	DMN1YQ6	Discovery agent	N.A.	Investigative	[70]
10S-hydroxylobelane	DM54AKV	Discovery agent	N.A.	Investigative	[70]
1S,2R-milnacipran	DM7Y5AN	Discovery agent	N.A.	Investigative	[71]
2-(2'-Aminoethyl)-5-benzyltetrahydrofuran	DMVTD1F	Discovery agent	N.A.	Investigative	[72]
2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine	DM1ULEX	Discovery agent	N.A.	Investigative	[73]
2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine	DM1SN37	Discovery agent	N.A.	Investigative	[73]
2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine	DMYVDJQ	Discovery agent	N.A.	Investigative	[73]
2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile	DMO9SP1	Discovery agent	N.A.	Investigative	[60]
2-(3-Methyl-piperazin-1-yl)-6-nitro-quinoline	DM1J4MT	Discovery agent	N.A.	Investigative	[74]
2-(Aminomethyl)-5-(1'-naphthethyl)tetrahydrofuran	DMU4MIC	Discovery agent	N.A.	Investigative	[72]
2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran	DMCUTY9	Discovery agent	N.A.	Investigative	[72]
2-(Aminomethyl)-5-(2'-naphthyl)tetrahydrofuran	DM157SO	Discovery agent	N.A.	Investigative	[72]
2-(Aminomethyl)-5-phenethyltetrahydrofuran	DMEZ7O2	Discovery agent	N.A.	Investigative	[72]
2-(N-Cyclopentylamino)-3'-methoxypropiophenone	DMVN1UI	Discovery agent	N.A.	Investigative	[67]
2-(N-Cyclopropylamino)-3-chloropropiophenone	DMNMES3	Discovery agent	N.A.	Investigative	[65]
2-(N-tert-Butylamino)-3',4'-dichloropropiophenone	DMKIEVP	Discovery agent	N.A.	Investigative	[65]
2-(tert-butylamino)-1-(3-chlorophenyl)butan-1-one	DMI457Y	Discovery agent	N.A.	Investigative	[67]
2-(tert-Butylamino)-3',4'-dichlorobutyrophenone	DMOJK8Y	Discovery agent	N.A.	Investigative	[65]
2-(tert-Butylamino)-3',4'-dichloropentanophenone	DMMUDQ7	Discovery agent	N.A.	Investigative	[65]
2-Amino-1-(4-ethylthiophenyl)butane	DM73FWA	Discovery agent	N.A.	Investigative	[66]
2-Amino-1-(4-ethylthiophenyl)propane	DMS5LKR	Discovery agent	N.A.	Investigative	[66]
2-Amino-1-(4-methylthiophenyl)butane	DMW7N3H	Discovery agent	N.A.	Investigative	[66]
2-Amino-1-(4-methylthiophenyl)propane	DMJ2Z9G	Discovery agent	N.A.	Investigative	[66]
2-Aminomethyl-5-(p-bromophenyl)tetrahydrofuran	DMCJUWK	Discovery agent	N.A.	Investigative	[72]
2-Aminomethyl-5-(p-chlorophenyl)tetrahydrofuran	DM3OTZY	Discovery agent	N.A.	Investigative	[72]
2-Aminomethyl-5-(p-methoxyphenyl)tetrahydrofuran	DMDG8FL	Discovery agent	N.A.	Investigative	[72]
2-Aminomethyl-5-(p-t-butylphenyl)tetrahydrofuran	DME4P7K	Discovery agent	N.A.	Investigative	[72]
2-Aminomethyl-5-(phenyl)tetrahydrofuran	DM413ZB	Discovery agent	N.A.	Investigative	[72]
2-N,N-Dimethylamino-1-(4-methylthiophenyl)propane	DMKSUVH	Discovery agent	N.A.	Investigative	[66]
2-N-(Isopropyl)amino-1-(4-methylthiophenyl)butane	DM0PT8R	Discovery agent	N.A.	Investigative	[66]
2-N-(n-Propyl)amino-1-(4-methylthiophenyl)butane	DMLJ30O	Discovery agent	N.A.	Investigative	[66]
2-N-Allylamino-1-(4-methylthiophenyl)propan	DM5S0BY	Discovery agent	N.A.	Investigative	[66]
2-N-Cyclopropylamino-1-(4-methylthiophenyl)butane	DMS0NW3	Discovery agent	N.A.	Investigative	[66]
2-N-Ethylamino-1-(4-ethylthiophenyl)butane	DMCYVS0	Discovery agent	N.A.	Investigative	[66]
2-N-Ethylamino-1-(4-ethylthiophenyl)propane	DM64093	Discovery agent	N.A.	Investigative	[66]
2-N-Ethylamino-1-(4-methylthiophenyl)butane	DMKA3V2	Discovery agent	N.A.	Investigative	[66]
2-N-Ethylamino-1-(4-methylthiophenyl)propane	DM6O1SY	Discovery agent	N.A.	Investigative	[66]
2-N-Hydroxyamino-1-(4-ethylthiophenyl)butane	DM2MH6J	Discovery agent	N.A.	Investigative	[66]
2-N-Hydroxyamino-1-(4-ethylthiophenyl)propane	DMIQGWK	Discovery agent	N.A.	Investigative	[66]
2-N-Hydroxyamino-1-(4-methylthiophenyl)butane	DME41NR	Discovery agent	N.A.	Investigative	[66]
2-N-Hydroxyamino-1-(4-methylthiophenyl)propane	DMZDYCW	Discovery agent	N.A.	Investigative	[66]
2-N-Methoxyamino-1-(4-methylthiophenyl)propane	DMHCVKJ	Discovery agent	N.A.	Investigative	[66]
2-N-Methylamino-1-(4-ethylthiophenyl)propane	DM1X5RY	Discovery agent	N.A.	Investigative	[66]
2-N-Methylamino-1-(4-methylthiophenyl)butane	DMCR49K	Discovery agent	N.A.	Investigative	[66]
2-N-Methylamino-1-(4-methylthiophenyl)propane	DMVLX1T	Discovery agent	N.A.	Investigative	[66]
2-N-Propargylamino-1-(4-methylthiophenyl)butane	DMLZCOU	Discovery agent	N.A.	Investigative	[66]
2-N-Propargylamino-1-(4-methylthiophenyl)propane	DM9HPG1	Discovery agent	N.A.	Investigative	[66]
2-Naphthalen-2-ylmethyl-4,5-dihydro-1H-imidazole	DMNMEPB	Discovery agent	N.A.	Investigative	[46]
2-phenoxy-3-(piperidin-4-yl)pyridine	DM6JNT5	Discovery agent	N.A.	Investigative	[73]
2-[1,4]Diazepan-1-yl-6-nitro-quinoline	DMEA2SR	Discovery agent	N.A.	Investigative	[74]
3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-amine	DMLV80B	Discovery agent	N.A.	Investigative	[75]
3-(1H-indol-3-yl)-N,N-dimethylpropan-1-amine	DM6Y2XK	Discovery agent	N.A.	Investigative	[76]
3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzamide	DM0YEGM	Discovery agent	N.A.	Investigative	[60]
3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile	DM6YJOU	Discovery agent	N.A.	Investigative	[60]
3-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol	DM6QZTB	Discovery agent	N.A.	Investigative	[60]
3-(3,4-dichlorophenyl)-2-nortropene	DMT3AW8	Discovery agent	N.A.	Investigative	[77]
3-(3-aminocyclopentyl)-1H-indole-5-carbonitrile	DMB6SP8	Discovery agent	N.A.	Investigative	[78]
3-(4-Chlorophenyl)-2-nortropene	DM71EUO	Discovery agent	N.A.	Investigative	[77]
3-(4-Fluorophenyl)-2-nortropene	DM8CK9M	Discovery agent	N.A.	Investigative	[77]
3-(4-Trifluoromethylphenyl)-2-nortropene	DMZB804	Discovery agent	N.A.	Investigative	[77]
3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine	DM2ETXB	Discovery agent	N.A.	Investigative	[73]
3-alpha-Phenylmethoxy-3-beta-phenyl-nortropane	DMO5IJA	Discovery agent	N.A.	Investigative	[77]
3-Bromo-6-nitro-2-piperazin-1-yl-quinoline	DMXZB5C	Discovery agent	N.A.	Investigative	[74]
3-p-Tolyl-8-aza-bicyclo[3.2.1]octane	DM0872E	Discovery agent	N.A.	Investigative	[79]
3-Phenyl-2-nortropene	DMAJMU6	Discovery agent	N.A.	Investigative	[77]
3alpha-(bis-chloro-phenylmethoxy)tropane	DMBUZWQ	Discovery agent	N.A.	Investigative	[80]
4-((naphthalen-2-yloxy)methyl)piperidine	DMIQHYZ	Discovery agent	N.A.	Investigative	[50]
4-(1H-indol-3-yl)-N,N-dimethylcyclohex-3-enamine	DM7Y1ZD	Discovery agent	N.A.	Investigative	[81]
4-(2-((3-fluorophenoxy)methyl)phenyl)piperidine	DMJ9CNA	Discovery agent	N.A.	Investigative	[62]
4-(2-((dimethylamino)methyl)phenoxy)benzonitrile	DM0MWVU	Discovery agent	N.A.	Investigative	[82]
4-(2-(2-fluoro-5-methylphenoxy)phenyl)piperidine	DM9UA0N	Discovery agent	N.A.	Investigative	[62]
4-(2-(2-fluorobenzyloxy)phenyl)piperidine	DMCR3VM	Discovery agent	N.A.	Investigative	[62]
4-(2-(3-chlorophenoxy)phenyl)piperidine	DM0IT5E	Discovery agent	N.A.	Investigative	[62]
4-(2-(3-fluorophenoxy)-4-methylphenyl)piperidine	DMEPB9L	Discovery agent	N.A.	Investigative	[62]
4-(2-(3-fluorophenoxy)phenyl)piperidine	DMZMEOG	Discovery agent	N.A.	Investigative	[62]
4-(2-(4-fluorobenzyloxy)phenyl)piperidine	DM29QLG	Discovery agent	N.A.	Investigative	[62]
4-(2-(4-fluorophenoxy)-4-methylphenyl)piperidine	DMJNB8C	Discovery agent	N.A.	Investigative	[62]
4-(2-(4-fluorophenoxy)phenyl)piperidine	DMFQT9O	Discovery agent	N.A.	Investigative	[62]
4-(2-(benzyloxy)-3-fluorophenyl)piperidine	DMM2NHZ	Discovery agent	N.A.	Investigative	[62]
4-(2-(benzyloxy)-6-fluorophenyl)piperidine	DMF3S50	Discovery agent	N.A.	Investigative	[62]
4-(2-(benzyloxy)phenyl)piperidine	DMOC7PY	Discovery agent	N.A.	Investigative	[62]
4-(2-(phenoxymethyl)phenyl)piperidine	DM0OFRQ	Discovery agent	N.A.	Investigative	[62]
4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine	DMQUAP2	Discovery agent	N.A.	Investigative	[73]
4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine	DMUBHRF	Discovery agent	N.A.	Investigative	[62]
4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine	DMJ2GW0	Discovery agent	N.A.	Investigative	[62]
4-(2-fluoro-6-phenoxyphenyl)piperidine	DMXIGWC	Discovery agent	N.A.	Investigative	[62]
4-(2-phenoxyphenyl)piperidine	DMB5IFA	Discovery agent	N.A.	Investigative	[62]
4-(3-fluoro-2-phenoxyphenyl)piperidine	DM1C3NZ	Discovery agent	N.A.	Investigative	[62]
4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one	DMM9X0G	Discovery agent	N.A.	Investigative	[83]
4-Allyl-6-nitro-2-piperazin-1-yl-quinoline	DM9WT8M	Discovery agent	N.A.	Investigative	[84]
4-Benzyl-6-nitro-2-piperazin-1-yl-quinoline	DMOBC0F	Discovery agent	N.A.	Investigative	[84]
4-Bromo-6-nitro-2-piperazin-1-yl-quinoline	DMH6OPI	Discovery agent	N.A.	Investigative	[84]
4-Chloro-6-nitro-2-piperazin-1-yl-quinoline	DM04OFE	Discovery agent	N.A.	Investigative	[84]
4-Furan-2-yl-6-nitro-2-piperazin-1-yl-quinoline	DMKT915	Discovery agent	N.A.	Investigative	[84]
4-Iodo-6-nitro-2-piperazin-1-yl-quinoline	DMC8D4R	Discovery agent	N.A.	Investigative	[84]
6,6-dimethyl-1-phenyl-3-aza-bicyclo[3.1.0]hexane	DMMZTE3	Discovery agent	N.A.	Investigative	[54]
6,8-Dinitro-2-piperazin-1-yl-quinoline	DME4193	Discovery agent	N.A.	Investigative	[74]
6-(3-aza-bicyclo[3.1.0]hexan-1-yl)quinoline	DMKFDQ7	Discovery agent	N.A.	Investigative	[54]
6-(piperidin-4-ylmethoxy)-2-naphthonitrile	DMBQKGY	Discovery agent	N.A.	Investigative	[50]
6-Bromo-2-piperazin-1-yl-quinoline	DMLT01H	Discovery agent	N.A.	Investigative	[74]
6-Chloro-2-piperazin-1-yl-quinoline	DMM41AQ	Discovery agent	N.A.	Investigative	[74]
6-Iodo-2-piperazin-1-yl-quinoline	DM31VLA	Discovery agent	N.A.	Investigative	[74]
6-Nitro-2-piperazin-1-yl-4-vinyl-quinoline	DMAOUQI	Discovery agent	N.A.	Investigative	[84]
6-Nitro-4-phenyl-2-piperazin-1-yl-quinoline	DMCEG6V	Discovery agent	N.A.	Investigative	[84]
7-(piperidin-4-ylmethoxy)-2-naphthonitrile	DM6I5K1	Discovery agent	N.A.	Investigative	[50]
8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane	DMOM4VS	Discovery agent	N.A.	Investigative	[79]
8R-hydroxylobel-9-ene	DML9HDA	Discovery agent	N.A.	Investigative	[85]
8R-hydroxylobelane	DMJ82TO	Discovery agent	N.A.	Investigative	[70]
8S-hydroxylobel-9-ene	DMRL3BK	Discovery agent	N.A.	Investigative	[70]
8S-hydroxylobelane	DMLONTS	Discovery agent	N.A.	Investigative	[70]
Beta-methoxyamphetamine	DMA9CSG	Discovery agent	N.A.	Investigative	[86]
Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine	DM4D7V6	Discovery agent	N.A.	Investigative	[87]
COCAINE.HCL	DMJRSIF	Discovery agent	N.A.	Investigative	[68]
CX-1001	DM7293Q	Solid tumour/cancer	2A00-2F9Z	Investigative	[20]
Cyclohexyl-(3,4-dichloro-phenyl)-acetonitrile	DMJEN45	Discovery agent	N.A.	Investigative	[88]
Cyclopentyl-(3,4-dichloro-phenyl)-acetonitrile	DMAKT65	Discovery agent	N.A.	Investigative	[88]
D-166A	DMQJD4P	Discovery agent	N.A.	Investigative	[89]
D-211A	DMIBOAK	Discovery agent	N.A.	Investigative	[89]
D-211B	DM54CKZ	Discovery agent	N.A.	Investigative	[89]
D-254C	DM6KFCO	Discovery agent	N.A.	Investigative	[89]
D-257A	DMN7E6Y	Discovery agent	N.A.	Investigative	[89]
D-257C	DM5GLJ2	Discovery agent	N.A.	Investigative	[89]
Difluorobenztropine	DM8ABD6	Discovery agent	N.A.	Investigative	[80]
Erythro-3,4-dichloromethylphenidate hydrochloride	DM8UVI3	Discovery agent	N.A.	Investigative	[68]
Isobutyl-(4-methyl-benzyl)-piperidin-4-yl-amine	DM293XH	Discovery agent	N.A.	Investigative	[90]
JNJ-28583867	DM5LEOR	Discovery agent	N.A.	Investigative	[91]
KF-A5	DMFBMYG	Discovery agent	N.A.	Investigative	[92]
KF-A6	DMQJ3T5	Discovery agent	N.A.	Investigative	[92]
MDL-28618	DMF76M8	Discovery agent	N.A.	Investigative	[49]
METHYLENEDIOXYAMPHETAMINE	DMP204G	Discovery agent	N.A.	Investigative	[66]
METHYLENEDIOXYMETHAMPHETAMINE	DMYVU47	Discovery agent	N.A.	Investigative	[93]
MMDA	DMUWVGP	Discovery agent	N.A.	Investigative	[94]
N*1*-(6-Nitro-quinolin-2-yl)-ethane-1,2-diamine	DME8KXT	Discovery agent	N.A.	Investigative	[74]
N,N-dimethyl(2-phenoxyphenyl)methanamine	DMWK91T	Discovery agent	N.A.	Investigative	[95]
N-(2-oxazolemethyl)milnacipran	DMVGP02	Discovery agent	N.A.	Investigative	[96]
N-(piperidin-4-yl)-N-propyl-2-naphthamide	DM9QIH4	Discovery agent	N.A.	Investigative	[57]
N-benzyl-N-isobutylpiperidin-4-amine	DM6QK7E	Discovery agent	N.A.	Investigative	[90]
N-cyclobutyl-N-(piperidin-4-yl)-2-naphthamide	DM1GTVW	Discovery agent	N.A.	Investigative	[57]
NISOXETINE	DMZBNH0	Discovery agent	N.A.	Investigative	[56]
norzotepine	DMS3N4X	Discovery agent	N.A.	Investigative	[97]
O-DESMETHYL TRAMADOL	DM8ZG2I	Discovery agent	N.A.	Investigative	[98]
Para-chloroamphetamine	DMOH75D	Discovery agent	N.A.	Investigative	[66]
PF-18298	DMJMU09	Discovery agent	N.A.	Investigative	[55]
PF-3409409	DMEZA0T	Attention deficit hyperactivity disorder	6A05.Z	Investigative	[99]
PF-526014	DMD8QOZ	Discovery agent	N.A.	Investigative	[55]
PYROVALERONE	DMV48S2	Discovery agent	N.A.	Investigative	[63]
QUIPAZINE	DMPY6IG	Discovery agent	N.A.	Investigative	[74]
R-226161	DM4BP7S	Discovery agent	N.A.	Investigative	[100]
R-NORDULOXETINE	DMGV4DS	Discovery agent	N.A.	Investigative	[59]
RTI-219	DM2QYXN	Discovery agent	N.A.	Investigative	[101]
S-34324	DMZLQ5W	Discovery agent	N.A.	Investigative	[102]
S33005	DM3Z6TI	Depression	6A70-6A7Z	Investigative	[42]
TEFLUDAZINE	DMRPFCS	Discovery agent	N.A.	Investigative	[103]
Threo-1-aza-5-phenyl[4.4.0]decane hydrochloride	DM4W1E8	Discovery agent	N.A.	Investigative	[68]
Threo-3,4-dichlororitalinol hydrochloride	DMA7GTH	N. A.	N. A.	Investigative	[68]
Trans-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine	DMEDC5I	Discovery agent	N.A.	Investigative	[104]
WIN-35065	DM6IH4F	Discovery agent	N.A.	Investigative	[101]
WIN-35066-2	DMOX1S0	N. A.	N. A.	Investigative	[105]
[3-(3,4-Dichloro-phenyl)-indan-1-yl]-methyl-amine	DM4BYEQ	Discovery agent	N.A.	Investigative	[64]
[3H]WIN35428	DMI8RU0	Discovery agent	N.A.	Investigative	[106]

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