Details of the Drug

General Information of Drug (ID: DMITX1G)

Drug Name
Citalopram derivative 1
Synonyms PMID29334795-Compound-59
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 324.4
Logarithm of the Partition Coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
ADMET Property
Clearance
The systemic clearance of drug is 330 mL/min []
Elimination
12-23% of an oral dose of citalopram is found unchanged in the urine, while 10% of the dose is found in the faeces []
Half-life
The concentration or amount of drug in body reduced by one-half in 35 hours []
Metabolism
The drug is metabolized via the liver [1]
Vd
The volume of distribution (Vd) of drug is 12 L/kg []
Chemical Identifiers
Formula
C20H21FN2O
IUPAC Name
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
Canonical SMILES
CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
InChI
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
InChIKey
WSEQXVZVJXJVFP-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
2771
ChEBI ID
CHEBI:77397
CAS Number
59729-33-8
TTD ID
D0R6LF
ACDINA ID
D00133

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histamine H1 receptor (H1R) TTTIBOJ HRH1_HUMAN Inhibitor [2]
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Histamine H1 receptor (H1R) DTT HRH1 6.74E-01 0.13 0.43
Serotonin transporter (SERT) DTT SLC6A4 8.76E-01 7.18E-05 6.19E-04
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Same Disease as Citalopram derivative 1
DDI Drug Name DDI Drug ID Severity Mechanism Disease REF
5-hydroxy-L-tryptophan DMDWZGJ Major Additive serotonergic effects by the combination of Citalopram derivative 1 and 5-hydroxy-L-tryptophan. Discovery agent [N.A.] [3]
Coadministration of a Drug Treating the Disease Different from Citalopram derivative 1 (Comorbidity)
DDI Drug Name DDI Drug ID Severity Mechanism Comorbidity REF
Methylene blue DMJAPE7 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Methylene blue. Acquired methaemoglobinaemia [3A93] [4]
Glimepiride DM5FSJA Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Glimepiride. Acute diabete complication [5A2Y] [5]
Repaglinide DM5SXUV Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Repaglinide. Acute diabete complication [5A2Y] [5]
Glibenclamide DM8JXPZ Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Glibenclamide. Acute diabete complication [5A2Y] [5]
Tolazamide DMIHRNA Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Tolazamide. Acute diabete complication [5A2Y] [5]
Nateglinide DMLK2QH Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Nateglinide. Acute diabete complication [5A2Y] [5]
Insulin-glulisine DMQI0FU Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Insulin-glulisine. Acute diabete complication [5A2Y] [5]
Acetohexamide DMR6N7H Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Acetohexamide. Acute diabete complication [5A2Y] [5]
Insulin-aspart DMX7V28 Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Insulin-aspart. Acute diabete complication [5A2Y] [6]
Glipizide DMZA5PQ Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Glipizide. Acute diabete complication [5A2Y] [5]
Ivosidenib DM8S6T7 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ivosidenib. Acute myeloid leukaemia [2A60] [7]
Midostaurin DMI6E0R Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Midostaurin. Acute myeloid leukaemia [2A60] [7]
Idarubicin DMM0XGL Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Idarubicin. Acute myeloid leukaemia [2A60] [7]
Daunorubicin DMQUSBT Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Daunorubicin. Acute myeloid leukaemia [2A60] [7]
Arn-509 DMT81LZ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Arn-509. Acute myeloid leukaemia [2A60] [7]
Gilteritinib DMTI0ZO Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Gilteritinib. Acute myeloid leukaemia [2A60] [7]
Oliceridine DM6MDCF Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Oliceridine. Acute pain [MG31] [8]
Terfenadine DM4KLPT Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Terfenadine. Allergic/hypersensitivity disorder [4A80-4A8Z] [7]
Tacrine DM51FY6 Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Tacrine. Alzheimer disease [8A20] [7]
Galantamine DMEO794 Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Galantamine. Alzheimer disease [8A20] [7]
Rivastigmine DMG629M Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Rivastigmine. Alzheimer disease [8A20] [7]
Metronidazole DMTIVEN Minor Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Metronidazole. Amoebiasis [1A36] [9]
Inotersen DMJ93CT Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Inotersen. Amyloidosis [5D00] [10]
Ranolazine DM0C9IL Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ranolazine. Angina pectoris [BA40] [7]
Bepridil DM0RKS4 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Bepridil. Angina pectoris [BA40] [7]
Dronedarone DMA8FS5 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Dronedarone. Angina pectoris [BA40] [7]
Nifedipine DMSVOZT Minor Decreased metabolism of Citalopram derivative 1 caused by Nifedipine mediated inhibition of CYP450 enzyme. Angina pectoris [BA40] [11]
Bedaquiline DM3906J Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Bedaquiline. Antimicrobial drug resistance [MG50-MG52] [7]
Buspirone DMBS632 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Buspirone. Anxiety disorder [6B00-6B0Z] [12]
Methylphenobarbital DMDSWAG Moderate Antagonize the effect of Citalopram derivative 1 when combined with Methylphenobarbital. Anxiety disorder [6B00-6B0Z] [13]
Hydroxyzine DMF8Y74 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Hydroxyzine. Anxiety disorder [6B00-6B0Z] [7]
Promazine DMZAL7W Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Promazine. Appearance/behaviour symptom [MB23] [7]
Cilostazol DMZMSCT Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Cilostazol. Arterial occlusive disease [BD40] [10]
Posaconazole DMUL5EW Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Posaconazole. Aspergillosis [1F20] [7]
Levalbuterol DM5YBO1 Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Levalbuterol. Asthma [CA23] [14]
Terbutaline DMD4381 Major Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Terbutaline. Asthma [CA23] [15]
Zafirlukast DMHNQOG Minor Decreased metabolism of Citalopram derivative 1 caused by Zafirlukast mediated inhibition of CYP450 enzyme. Asthma [CA23] [11]
Pirbuterol DMI5678 Moderate Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Pirbuterol. Asthma [CA23] [15]
Isoetharine DMITSEH Moderate Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Isoetharine. Asthma [CA23] [15]
Formoterol DMSOURV Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Formoterol. Asthma [CA23] [15]
Atomoxetine DM5L6HI Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Atomoxetine. Attention deficit hyperactivity disorder [6A05] [7]
Lisdexamfetamine DM6W8V5 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Lisdexamfetamine. Attention deficit hyperactivity disorder [6A05] [8]
Methylphenidate DM7SJD6 Moderate Decreased metabolism of Citalopram derivative 1 caused by Methylphenidate. Attention deficit hyperactivity disorder [6A05] [16]
Desipramine DMT2FDC Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Desipramine. Attention deficit hyperactivity disorder [6A05] [8]
Ofloxacin DM0VQN3 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ofloxacin. Bacterial infection [1A00-1C4Z] [7]
Ciprofloxacin XR DM2NLS9 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ciprofloxacin XR. Bacterial infection [1A00-1C4Z] [7]
Dalfopristin DM4LTKV Minor Decreased metabolism of Citalopram derivative 1 caused by Dalfopristin mediated inhibition of CYP450 enzyme. Bacterial infection [1A00-1C4Z] [11]
Clarithromycin DM4M1SG Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Clarithromycin. Bacterial infection [1A00-1C4Z] [7]
Sulfamethoxazole DMB08GE Minor Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Sulfamethoxazole. Bacterial infection [1A00-1C4Z] [7]
Chloramphenicol DMFXEWT Minor Decreased metabolism of Citalopram derivative 1 caused by Chloramphenicol mediated inhibition of CYP450 enzyme. Bacterial infection [1A00-1C4Z] [11]
Linezolid DMGFPU2 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Linezolid. Bacterial infection [1A00-1C4Z] [17]
Gemifloxacin DMHT34O Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Gemifloxacin. Bacterial infection [1A00-1C4Z] [7]
Norfloxacin DMIZ6W2 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Norfloxacin. Bacterial infection [1A00-1C4Z] [7]
Levofloxacin DMS60RB Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Levofloxacin. Bacterial infection [1A00-1C4Z] [7]
Moxifloxacin DMU8V4S Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Moxifloxacin. Bacterial infection [1A00-1C4Z] [7]
Troleandomycin DMUZNIG Minor Decreased metabolism of Citalopram derivative 1 caused by Troleandomycin mediated inhibition of CYP450 enzyme. Bacterial infection [1A00-1C4Z] [11]
Lomefloxacin DMVRH9C Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Lomefloxacin. Bacterial infection [1A00-1C4Z] [7]
Telithromycin DMZ4P3A Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Telithromycin. Bacterial infection [1A00-1C4Z] [7]
Lamotrigine DM8SXYG Moderate Antagonize the effect of Citalopram derivative 1 when combined with Lamotrigine. Bipolar disorder [6A60] [13]
Pexidartinib DMS2J0Z Major Decreased metabolism of Citalopram derivative 1 caused by Pexidartinib mediated inhibition of CYP450 enzyme. Bone/articular cartilage neoplasm [2F7B] [18]
Loperamide DMOJZQ9 Moderate Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Loperamide. Bowel habit change [ME05] [19]
Eribulin DM1DX4Q Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Eribulin. Breast cancer [2C60-2C6Y] [7]
Lapatinib DM3BH1Y Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Lapatinib. Breast cancer [2C60-2C6Y] [7]
Tucatinib DMBESUA Minor Decreased metabolism of Citalopram derivative 1 caused by Tucatinib mediated inhibition of CYP450 enzyme. Breast cancer [2C60-2C6Y] [11]
Palbociclib DMD7L94 Minor Decreased metabolism of Citalopram derivative 1 caused by Palbociclib mediated inhibition of CYP450 enzyme. Breast cancer [2C60-2C6Y] [11]
Letrozole DMH07Y3 Major Decreased metabolism of Citalopram derivative 1 caused by Letrozole mediated inhibition of CYP450 enzyme. Breast cancer [2C60-2C6Y] [18]
Tamoxifen DMLB0EZ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Tamoxifen. Breast cancer [2C60-2C6Y] [7]
Toremifene DMQYUWG Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Toremifene. Breast cancer [2C60-2C6Y] [7]
Bosutinib DMTI8YE Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Bosutinib. Breast cancer [2C60-2C6Y] [7]
Trastuzumab Emtansine DMU1LXS Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Trastuzumab Emtansine. Breast cancer [2C60-2C6Y] [20]
Mannitol DMSCDY9 Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Mannitol. Bronchiectasis [CA24] [21]
Grepafloxacin DMGLX0T Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Grepafloxacin. Bronchitis [CA20] [7]
Sotalol DML60TN Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Sotalol. Cardiac arrhythmia [BC9Z] [7]
PF-04449913 DMSB068 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and PF-04449913. Chronic myelomonocytic leukaemia [2A40] [7]
Pregabalin DMDVP3B Moderate Antagonize the effect of Citalopram derivative 1 when combined with Pregabalin. Chronic obstructive pulmonary disease [CA22] [13]
Vilanterol DMF5EK1 Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Vilanterol. Chronic obstructive pulmonary disease [CA22] [14]
Salmeterol DMIEU69 Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Salmeterol. Chronic obstructive pulmonary disease [CA22] [15]
Arformoterol DMYM974 Moderate Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Arformoterol. Chronic obstructive pulmonary disease [CA22] [15]
Phenylbutazone DMAYL0T Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Phenylbutazone. Chronic pain [MG30] [10]
Dihydrocodeine DMB0FWL Moderate Additive serotonergic effects by the combination of Citalopram derivative 1 and Dihydrocodeine. Chronic pain [MG30] [22]
Ketoprofen DMRKXPT Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Ketoprofen. Chronic pain [MG30] [10]
Morphine DMRMS0L Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Morphine. Chronic pain [MG30] [22]
Levetiracetam DMTGDN8 Moderate Antagonize the effect of Citalopram derivative 1 when combined with Levetiracetam. Chronic pain [MG30] [13]
Levomilnacipran DMV26S8 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Levomilnacipran. Chronic pain [MG30] [12]
Anisindione DM2C48U Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Anisindione. Coagulation defect [3B10] [10]
Irinotecan DMP6SC2 Minor Decreased metabolism of Citalopram derivative 1 caused by Irinotecan mediated inhibition of CYP450 enzyme. Colorectal cancer [2B91] [23]
Oxaliplatin DMQNWRD Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Oxaliplatin. Colorectal cancer [2B91] [7]
Isoproterenol DMK7MEY Major Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Isoproterenol. Conduction disorder [BC63] [15]
Olopatadine DMKMWQG Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Olopatadine. Conjunctiva disorder [9A60] [24]
Halothane DM80OZ5 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Halothane. Corneal disease [9A76-9A78] [7]
Sevoflurane DMC9O43 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Sevoflurane. Corneal disease [9A76-9A78] [7]
Remifentanil DMZTXCH Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Remifentanil. Corneal disease [9A76-9A78] [12]
Probucol DMVZQ2M Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Probucol. Coronary atherosclerosis [BA80] [7]
Ardeparin DMYRX8B Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Ardeparin. Coronary thrombosis [BA43] [10]
Methadone DMTW6IU Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Methadone. Cough [MD12] [7]
Dextromethorphan DMUDJZM Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Dextromethorphan. Cough [MD12] [12]
Clofazimine DMEBOFW Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Clofazimine. Crohn disease [DD70] [7]
Mifepristone DMGZQEF Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Mifepristone. Cushing syndrome [5A70] [7]
Pasireotide DMHM7JS Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Pasireotide. Cushing syndrome [5A70] [7]
Osilodrostat DMIJC9X Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Osilodrostat. Cushing syndrome [5A70] [7]
Lumacaftor DMCLWDJ Moderate Increased metabolism of Citalopram derivative 1 caused by Lumacaftor mediated induction of CYP450 enzyme. Cystic fibrosis [CA25] [25]
Ivacaftor DMZC1HS Minor Decreased metabolism of Citalopram derivative 1 caused by Ivacaftor mediated inhibition of CYP450 enzyme. Cystic fibrosis [CA25] [11]
Ethanol DMDRQZU Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Ethanol. Cystitis [GC00] [24]
MK-8228 DMOB58Q Minor Decreased metabolism of Citalopram derivative 1 caused by MK-8228 mediated inhibition of CYP450 enzyme. Cytomegaloviral disease [1D82] [11]
Danaparoid DM6CLBN Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Danaparoid. Deep vein thrombosis [BD71] [10]
Rivaroxaban DMQMBZ1 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Rivaroxaban. Deep vein thrombosis [BD71] [10]
Aprepitant DM053KT Minor Decreased metabolism of Citalopram derivative 1 caused by Aprepitant mediated inhibition of CYP450 enzyme. Depression [6A70-6A7Z] [11]
Sertraline DM0FB1J Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Sertraline. Depression [6A70-6A7Z] [8]
Trimipramine DM1SC8M Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Trimipramine. Depression [6A70-6A7Z] [8]
Cyclobenzaprine DM1YBRM Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Cyclobenzaprine. Depression [6A70-6A7Z] [12]
Imipramine DM2NUH3 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Imipramine. Depression [6A70-6A7Z] [8]
Fluoxetine DM3PD2C Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Fluoxetine. Depression [6A70-6A7Z] [8]
Nortriptyline DM4KDYJ Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Nortriptyline. Depression [6A70-6A7Z] [8]
Vilazodone DM4LECQ Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Vilazodone. Depression [6A70-6A7Z] [12]
Nefazodone DM4ZS8M Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Nefazodone. Depression [6A70-6A7Z] [12]
Selegiline DM6034S Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Selegiline. Depression [6A70-6A7Z] [26]
Vortioxetine DM6F1PU Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Vortioxetine. Depression [6A70-6A7Z] [12]
Duloxetine DM9BI7M Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Duloxetine. Depression [6A70-6A7Z] [12]
Milnacipran DMBFE74 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Milnacipran. Depression [6A70-6A7Z] [12]
Escitalopram DMFK9HG Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Escitalopram. Depression [6A70-6A7Z] [27]
Tranylcypromine DMGB5RE Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Tranylcypromine. Depression [6A70-6A7Z] [26]
Desvenlafaxine DMHD4PE Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Desvenlafaxine. Depression [6A70-6A7Z] [12]
Phenelzine DMHIDUE Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Phenelzine. Depression [6A70-6A7Z] [26]
Clomipramine DMINRKW Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Clomipramine. Depression [6A70-6A7Z] [8]
Trazodone DMK1GBJ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Trazodone. Depression [6A70-6A7Z] [8]
Amitriptyline DMK7F9S Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Amitriptyline. Depression [6A70-6A7Z] [8]
Amoxapine DMKITQE Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Amoxapine. Depression [6A70-6A7Z] [8]
Mirtazapine DML53ZJ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Mirtazapine. Depression [6A70-6A7Z] [8]
Protriptyline DMNHTZI Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Protriptyline. Depression [6A70-6A7Z] [8]
Doxepin DMPI98T Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Doxepin. Depression [6A70-6A7Z] [8]
Maprotiline DMPWB7T Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Maprotiline. Depression [6A70-6A7Z] [7]
Venlafaxine DMR6QH0 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Venlafaxine. Depression [6A70-6A7Z] [8]
Tetrabenazine DMYWQ0O Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Tetrabenazine. Dissociative neurological symptom disorder [6B60] [7]
Ingrezza DMVPLNC Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ingrezza. Dystonic disorder [8A02] [7]
Fenfluramine DM0762O Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Fenfluramine. Epilepsy/seizure [8A61-8A6Z] [12]
Zonisamide DM0DTF7 Moderate Antagonize the effect of Citalopram derivative 1 when combined with Zonisamide. Epilepsy/seizure [8A61-8A6Z] [13]
Felbamate DM1V5ZS Major Decreased metabolism of Citalopram derivative 1 caused by Felbamate mediated inhibition of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [18]
Oxcarbazepine DM5PU6O Major Decreased metabolism of Citalopram derivative 1 caused by Oxcarbazepine mediated inhibition of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [18]
Mephenytoin DM5UGDK Moderate Antagonize the effect of Citalopram derivative 1 when combined with Mephenytoin. Epilepsy/seizure [8A61-8A6Z] [13]
Methsuximide DM6L5VO Moderate Antagonize the effect of Citalopram derivative 1 when combined with Methsuximide. Epilepsy/seizure [8A61-8A6Z] [13]
Valproate DMCFE9I Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Valproate. Epilepsy/seizure [8A61-8A6Z] [13]
Ethosuximide DMDZ9LT Moderate Antagonize the effect of Citalopram derivative 1 when combined with Ethosuximide. Epilepsy/seizure [8A61-8A6Z] [13]
Tiagabine DMKSQG0 Moderate Antagonize the effect of Citalopram derivative 1 when combined with Tiagabine. Epilepsy/seizure [8A61-8A6Z] [13]
Phenacemide DMOHS9P Moderate Antagonize the effect of Citalopram derivative 1 when combined with Phenacemide. Epilepsy/seizure [8A61-8A6Z] [13]
Paramethadione DMR5ZUP Moderate Antagonize the effect of Citalopram derivative 1 when combined with Paramethadione. Epilepsy/seizure [8A61-8A6Z] [13]
Brivaracetam DMSEPK8 Moderate Antagonize the effect of Citalopram derivative 1 when combined with Brivaracetam. Epilepsy/seizure [8A61-8A6Z] [13]
Lacosamide DMVM6QR Moderate Antagonize the effect of Citalopram derivative 1 when combined with Lacosamide. Epilepsy/seizure [8A61-8A6Z] [13]
Rufinamide DMWE60C Moderate Antagonize the effect of Citalopram derivative 1 when combined with Rufinamide. Epilepsy/seizure [8A61-8A6Z] [13]
Ethotoin DMXWOCP Moderate Antagonize the effect of Citalopram derivative 1 when combined with Ethotoin. Epilepsy/seizure [8A61-8A6Z] [13]
Vigabatrin DMYT0OG Moderate Antagonize the effect of Citalopram derivative 1 when combined with Vigabatrin. Epilepsy/seizure [8A61-8A6Z] [13]
Carbamazepine DMZOLBI Minor Increased metabolism of Citalopram derivative 1 caused by Carbamazepine mediated induction of CYP450 enzyme. Epilepsy/seizure [8A61-8A6Z] [28]
Eslicarbazepine DMZREFQ Moderate Antagonize the effect of Citalopram derivative 1 when combined with Eslicarbazepine. Epilepsy/seizure [8A61-8A6Z] [13]
Timolol DM3NXRU Moderate Decreased metabolism of Citalopram derivative 1 caused by Timolol mediated inhibition of CYP450 enzyme. Essential hypertension [BA00] [29]
Ethacrynic acid DM60QMR Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Ethacrynic acid. Essential hypertension [BA00] [21]
Bendroflumethiazide DM7EVLC Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Bendroflumethiazide. Essential hypertension [BA00] [21]
Benzthiazide DMQWZ0H Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Benzthiazide. Essential hypertension [BA00] [21]
Mefenamic acid DMK7HFI Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Mefenamic acid. Female pelvic pain [GA34] [10]
Tazemetostat DMWP1BH Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Tazemetostat. Follicular lymphoma [2A80] [10]
Solifenacin DMG592Q Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Solifenacin. Functional bladder disorder [GC50] [7]
Tolterodine DMSHPW8 Minor Decreased metabolism of Citalopram derivative 1 caused by Tolterodine mediated inhibition of CYP450 enzyme. Functional bladder disorder [GC50] [30]
Darifenacin DMWXLYZ Moderate Decreased metabolism of Citalopram derivative 1 caused by Darifenacin mediated inhibition of CYP450 enzyme. Functional bladder disorder [GC50] [31]
Itraconazole DMCR1MV Minor Decreased metabolism of Citalopram derivative 1 caused by Itraconazole mediated inhibition of CYP450 enzyme. Fungal infection [1F29-1F2F] [11]
Clotrimazole DMMFCIH Minor Decreased metabolism of Citalopram derivative 1 caused by Clotrimazole mediated inhibition of CYP450 enzyme. Fungal infection [1F29-1F2F] [11]
Miconazole DMPMYE8 Minor Decreased metabolism of Citalopram derivative 1 caused by Miconazole mediated inhibition of CYP450 enzyme. Fungal infection [1F29-1F2F] [11]
Ketoconazole DMPZI3Q Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ketoconazole. Fungal infection [1F29-1F2F] [7]
Omeprazole DM471KJ Major Decreased metabolism of Citalopram derivative 1 caused by Omeprazole mediated inhibition of CYP450 enzyme. Gastro-oesophageal reflux disease [DA22] [18]
Cimetidine DMH61ZB Major Decreased metabolism of Citalopram derivative 1 caused by Cimetidine mediated inhibition of CYP450 enzyme. Gastro-oesophageal reflux disease [DA22] [18]
Cisapride DMY7PED Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Cisapride. Gastro-oesophageal reflux disease [DA22] [7]
Sunitinib DMCBJSR Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Sunitinib. Gastrointestinal stromal tumour [2B5B] [7]
Avapritinib DMK2GZX Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Avapritinib. Gastrointestinal stromal tumour [2B5B] [10]
Acetazolamide DM1AF5U Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Acetazolamide. Glaucoma [9C61] [21]
Methazolamide DM7J2TA Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Methazolamide. Glaucoma [9C61] [21]
Dichlorphenamide DMH7IDQ Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Dichlorphenamide. Glaucoma [9C61] [21]
Sulfinpyrazone DMEV954 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Sulfinpyrazone. Gout [FA25] [10]
Ergotamine DMKR3C5 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Ergotamine. Headache [8A80-8A84] [12]
Spironolactone DM2AQ5N Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Spironolactone. Heart failure [BD10-BD1Z] [21]
Triamterene DM2HU9I Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Triamterene. Heart failure [BD10-BD1Z] [21]
Carvedilol DMHTEAO Moderate Decreased metabolism of Citalopram derivative 1 caused by Carvedilol mediated inhibition of CYP450 enzyme. Heart failure [BD10-BD1Z] [29]
Chlorothiazide DMLHESP Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Chlorothiazide. Heart failure [BD10-BD1Z] [21]
Furosemide DMMQ8ZG Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Furosemide. Heart failure [BD10-BD1Z] [21]
Amiloride DMRTSGP Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Amiloride. Heart failure [BD10-BD1Z] [21]
Bumetanide DMRV7H0 Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Bumetanide. Heart failure [BD10-BD1Z] [21]
Hydroflumethiazide DMVPUQI Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Hydroflumethiazide. Heart failure [BD10-BD1Z] [21]
Boceprevir DMBSHMF Minor Decreased metabolism of Citalopram derivative 1 caused by Boceprevir mediated inhibition of CYP450 enzyme. Hepatitis virus infection [1E50-1E51] [11]
Telaprevir DMMRV29 Minor Decreased metabolism of Citalopram derivative 1 caused by Telaprevir mediated inhibition of CYP450 enzyme. Hepatitis virus infection [1E50-1E51] [11]
Isoniazid DM5JVS3 Major Decreased metabolism of Citalopram derivative 1 caused by Isoniazid mediated inhibition of CYP450 enzyme. HIV-infected patients with tuberculosis [1B10-1B14] [18]
Rifampin DMA8J1G Moderate Increased metabolism of Citalopram derivative 1 caused by Rifampin mediated induction of CYP450 enzyme. HIV-infected patients with tuberculosis [1B10-1B14] [32]
Procarbazine DMIK367 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Procarbazine. Hodgkin lymphoma [2B30] [26]
Indinavir DM0T3YH Minor Decreased metabolism of Citalopram derivative 1 caused by Indinavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Delavirdine DM3NF5G Major Decreased metabolism of Citalopram derivative 1 caused by Delavirdine mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Fosamprenavir DM4W9B3 Minor Decreased metabolism of Citalopram derivative 1 caused by Fosamprenavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Fostemsavir DM50ILT Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Fostemsavir. Human immunodeficiency virus disease [1C60-1C62] [7]
Nevirapine DM6HX9B Moderate Increased metabolism of Citalopram derivative 1 caused by Nevirapine mediated induction of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [9]
Cobicistat DM6L4H2 Minor Decreased metabolism of Citalopram derivative 1 caused by Cobicistat mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Efavirenz DMC0GSJ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Efavirenz. Human immunodeficiency virus disease [1C60-1C62] [7]
Saquinavir DMG814N Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Saquinavir. Human immunodeficiency virus disease [1C60-1C62] [7]
Etravirine DMGV8QU Major Decreased metabolism of Citalopram derivative 1 caused by Etravirine mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [33]
Lopinavir DMITQS0 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Lopinavir. Human immunodeficiency virus disease [1C60-1C62] [7]
Rilpivirine DMJ0QOW Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Rilpivirine. Human immunodeficiency virus disease [1C60-1C62] [7]
Amprenavir DMLMXE0 Minor Decreased metabolism of Citalopram derivative 1 caused by Amprenavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Darunavir DMN3GCH Minor Decreased metabolism of Citalopram derivative 1 caused by Darunavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Atazanavir DMSYRBX Minor Decreased metabolism of Citalopram derivative 1 caused by Atazanavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Ritonavir DMU764S Minor Decreased metabolism of Citalopram derivative 1 caused by Ritonavir mediated inhibition of CYP450 enzyme. Human immunodeficiency virus disease [1C60-1C62] [11]
Fenofibrate DMFKXDY Major Decreased metabolism of Citalopram derivative 1 caused by Fenofibrate mediated inhibition of CYP450 enzyme. Hyper-lipoproteinaemia [5C80] [9]
BMS-201038 DMQTAGO Minor Decreased metabolism of Citalopram derivative 1 caused by BMS-201038 mediated inhibition of CYP450 enzyme. Hyper-lipoproteinaemia [5C80] [11]
Nebivolol DM7F1PA Moderate Decreased metabolism of Citalopram derivative 1 caused by Nebivolol mediated inhibition of CYP450 enzyme. Hypertension [BA00-BA04] [29]
Verapamil DMA7PEW Minor Decreased metabolism of Citalopram derivative 1 caused by Verapamil mediated inhibition of CYP450 enzyme. Hypertension [BA00-BA04] [11]
Diltiazem DMAI7ZV Minor Decreased metabolism of Citalopram derivative 1 caused by Diltiazem mediated inhibition of CYP450 enzyme. Hypertension [BA00-BA04] [11]
Indapamide DMGN1PW Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Indapamide. Hypertension [BA00-BA04] [21]
Trichlormethiazide DMHAQCO Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Trichlormethiazide. Hypertension [BA00-BA04] [21]
Metoprolol DMOJ0V6 Moderate Decreased metabolism of Citalopram derivative 1 caused by Metoprolol mediated inhibition of CYP450 enzyme. Hypertension [BA00-BA04] [29]
Hydrochlorothiazide DMUSZHD Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Hydrochlorothiazide. Hypertension [BA00-BA04] [21]
Dipyridamole DMXY30O Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Dipyridamole. Hypertension [BA00-BA04] [10]
Conivaptan DM1V329 Minor Decreased metabolism of Citalopram derivative 1 caused by Conivaptan mediated inhibition of CYP450 enzyme. Hypo-osmolality/hyponatraemia [5C72] [11]
Berotralstat DMWA2DZ Moderate Decreased metabolism of Citalopram derivative 1 caused by Berotralstat mediated inhibition of CYP450 enzyme. Innate/adaptive immunodeficiency [4A00] [34]
Temazepam DM02A65 Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Temazepam. Insomnia [7A00-7A0Z] [9]
Polyethylene glycol DM4I1JP Moderate Increased risk of lowers seizure threshold by the combination of Citalopram derivative 1 and Polyethylene glycol. Irritable bowel syndrome [DD91] [7]
Phenolphthalein DM5SICT Moderate Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Phenolphthalein. Irritable bowel syndrome [DD91] [7]
Glycerol phenylbutyrate DMDGRQO Moderate Decreased metabolism of Citalopram derivative 1 caused by Glycerol phenylbutyrate mediated inhibition of CYP450 enzyme. Liver disease [DB90-DB9Z] [32]
Porfimer Sodium DM7ZWNY Moderate Increased risk of photosensitivity reactions by the combination of Citalopram derivative 1 and Porfimer Sodium. Lung cancer [2C25] [35]
Ceritinib DMB920Z Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ceritinib. Lung cancer [2C25] [7]
Osimertinib DMRJLAT Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Osimertinib. Lung cancer [2C25] [7]
Selpercatinib DMZR15V Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Selpercatinib. Lung cancer [2C25] [7]
Halofantrine DMOMK1V Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Halofantrine. Malaria [1F40-1F45] [7]
Chloroquine DMSI5CB Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Chloroquine. Malaria [1F40-1F45] [7]
Hydroxychloroquine DMSIVND Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Hydroxychloroquine. Malaria [1F40-1F45] [7]
Quinine DMSWYF5 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Quinine. Malaria [1F40-1F45] [7]
Primaquine DMWQ16I Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Primaquine. Malaria [1F40-1F45] [7]
Mefloquine DMWT905 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Mefloquine. Malaria [1F40-1F45] [7]
Inotuzumab ozogamicin DMAC130 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Inotuzumab ozogamicin. Malignant haematopoietic neoplasm [2B33] [7]
Idelalisib DM602WT Minor Decreased metabolism of Citalopram derivative 1 caused by Idelalisib mediated inhibition of CYP450 enzyme. Mature B-cell leukaemia [2A82] [11]
IPI-145 DMWA24P Minor Decreased metabolism of Citalopram derivative 1 caused by IPI-145 mediated inhibition of CYP450 enzyme. Mature B-cell leukaemia [2A82] [11]
Arsenic trioxide DM61TA4 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Arsenic trioxide. Mature B-cell lymphoma [2A85] [7]
Acalabrutinib DM7GCVW Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Acalabrutinib. Mature B-cell lymphoma [2A85] [10]
Ibrutinib DMHZCPO Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Ibrutinib. Mature B-cell lymphoma [2A85] [10]
Ponatinib DMYGJQO Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Ponatinib. Mature B-cell lymphoma [2A85] [10]
Vemurafenib DM62UG5 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Vemurafenib. Melanoma [2C30] [7]
LGX818 DMNQXV8 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and LGX818. Melanoma [2C30] [7]
Danazol DML8KTN Minor Decreased metabolism of Citalopram derivative 1 caused by Danazol mediated inhibition of CYP450 enzyme. Menstrual cycle bleeding disorder [GA20] [11]
Allopregnanolone DMNLHAC Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Allopregnanolone. Mental/behavioural/neurodevelopmental disorder [6E20-6E8Z] [36]
Zolmitriptan DM1IB4Q Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Zolmitriptan. Migraine [8A80] [12]
Dihydroergotamine DM5IKUF Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Dihydroergotamine. Migraine [8A80] [12]
Propranolol DM79NTF Moderate Decreased metabolism of Citalopram derivative 1 caused by Propranolol mediated inhibition of CYP450 enzyme. Migraine [8A80] [29]
Frovatriptan DM7RE8P Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Frovatriptan. Migraine [8A80] [12]
Rizatriptan DMDJMA3 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Rizatriptan. Migraine [8A80] [12]
Naratriptan DMO50U2 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Naratriptan. Migraine [8A80] [12]
Sumatriptan DMVYXR8 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Sumatriptan. Migraine [8A80] [12]
Eletriptan DMW649X Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Eletriptan. Migraine [8A80] [12]
Flibanserin DM70DTN Moderate Decreased metabolism of Citalopram derivative 1 caused by Flibanserin mediated inhibition of CYP450 enzyme. Mood disorder [6A60-6E23] [37]
Panobinostat DM58WKG Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Panobinostat. Multiple myeloma [2A83] [7]
Thalidomide DM70BU5 Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Thalidomide. Multiple myeloma [2A83] [38]
Siponimod DM2R86O Major Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Siponimod. Multiple sclerosis [8A40] [9]
Fingolimod DM5JVAN Major Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Fingolimod. Multiple sclerosis [8A40] [7]
Ozanimod DMT6AM2 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Ozanimod. Multiple sclerosis [8A40] [39]
Romidepsin DMT5GNL Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Romidepsin. Mycosis fungoides [2B01] [7]
Fedratinib DM4ZBK6 Major Decreased metabolism of Citalopram derivative 1 caused by Fedratinib mediated inhibition of CYP450 enzyme. Myeloproliferative neoplasm [2A20] [18]
Nilotinib DM7HXWT Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Nilotinib. Myeloproliferative neoplasm [2A20] [7]
Imatinib DM7RJXL Minor Decreased metabolism of Citalopram derivative 1 caused by Imatinib mediated inhibition of CYP450 enzyme. Myeloproliferative neoplasm [2A20] [11]
Dasatinib DMJV2EK Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Dasatinib. Myeloproliferative neoplasm [2A20] [7]
Vorapaxar DMA16BR Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Vorapaxar. Myocardial infarction [BA41-BA43] [10]
Tirofiban DMQG17S Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Tirofiban. Myocardial infarction [BA41-BA43] [10]
Modafinil DMYILBE Major Decreased metabolism of Citalopram derivative 1 caused by Modafinil mediated inhibition of CYP450 enzyme. Narcolepsy [7A20] [18]
Droperidol DM0DXA8 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Droperidol. Nausea/vomiting [MD90] [7]
Prochlorperazine DM53SRA Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Prochlorperazine. Nausea/vomiting [MD90] [40]
Promethazine DM6I5GR Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Promethazine. Nausea/vomiting [MD90] [40]
Palonosetron DMBHMOX Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Palonosetron. Nausea/vomiting [MD90] [7]
Granisetron DMIUW25 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Granisetron. Nausea/vomiting [MD90] [7]
Dolasetron DMMG26Z Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Dolasetron. Nausea/vomiting [MD90] [7]
Ondansetron DMOTQ1I Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ondansetron. Nausea/vomiting [MD90] [7]
E-2007 DMJDYNQ Moderate Antagonize the effect of Citalopram derivative 1 when combined with E-2007. Neuropathy [8C0Z] [13]
Bupropion DM5PCS7 Major Increased risk of lowers seizure threshold by the combination of Citalopram derivative 1 and Bupropion. Nicotine use disorder [6C4A] [7]
Entrectinib DMMPTLH Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Entrectinib. Non-small cell lung cancer [2C25] [7]
Sibutramine DMFJTDI Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Sibutramine. Obesity [5B80-5B81] [8]
Lorcaserin DMG6OYJ Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Lorcaserin. Obesity [5B80-5B81] [41]
Dexfenfluramine DMJ7YDS Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Dexfenfluramine. Obesity [5B80-5B81] [12]
Chlorthalidone DM4DMBT Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Chlorthalidone. Oedema [MG29] [21]
Polythiazide DMCH80F Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Polythiazide. Oedema [MG29] [21]
Urea DMUK75B Moderate Increased risk of hyponatremia by the combination of Citalopram derivative 1 and Urea. Oesophagitis [DA24] [21]
Levomethadyl Acetate DM06HG5 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Levomethadyl Acetate. Opioid use disorder [6C43] [7]
Lofexidine DM1WXA6 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Lofexidine. Opioid use disorder [6C43] [7]
Diclofenac DMPIHLS Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Diclofenac. Osteoarthritis [FA00-FA05] [10]
Rucaparib DM9PVX8 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Rucaparib. Ovarian cancer [2C73] [7]
Pentazocine DM1XBHS Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Pentazocine. Pain [MG30-MG3Z] [12]
Dextropropoxyphene DM23HCX Major Additive CNS depression effects by the combination of Citalopram derivative 1 and Dextropropoxyphene. Pain [MG30-MG3Z] [42]
Butorphanol DM5KYPJ Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Butorphanol. Pain [MG30-MG3Z] [22]
Oxymorphone DM65AGJ Moderate Additive serotonergic effects by the combination of Citalopram derivative 1 and Oxymorphone. Pain [MG30-MG3Z] [22]
Aspirin DM672AH Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Aspirin. Pain [MG30-MG3Z] [20]
Etodolac DM6WJO9 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Etodolac. Pain [MG30-MG3Z] [10]
Diflunisal DM7EN8I Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Diflunisal. Pain [MG30-MG3Z] [10]
Ibuprofen DM8VCBE Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Ibuprofen. Pain [MG30-MG3Z] [10]
Nabumetone DMAT2XH Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Nabumetone. Pain [MG30-MG3Z] [10]
Levorphanol DMGS80V Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Levorphanol. Pain [MG30-MG3Z] [22]
Hydromorphone DMHP21E Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Hydromorphone. Pain [MG30-MG3Z] [22]
Dezocine DMJDB0Y Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Dezocine. Pain [MG30-MG3Z] [22]
Codeine DMJX6ZG Moderate Decreased metabolism of Citalopram derivative 1 caused by Codeine mediated inhibition of CYP450 enzyme. Pain [MG30-MG3Z] [43]
Nalbuphine DMOSQGU Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Nalbuphine. Pain [MG30-MG3Z] [22]
Buprenorphine DMPRI8G Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Buprenorphine. Pain [MG30-MG3Z] [7]
Hydrocodone DMQ2JO5 Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Hydrocodone. Pain [MG30-MG3Z] [22]
Piroxicam DMTK234 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Piroxicam. Pain [MG30-MG3Z] [10]
Meperidine DMX4GND Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Meperidine. Pain [MG30-MG3Z] [12]
Oxycodone DMXLKHV Moderate Additive serotonergic effects by the combination of Citalopram derivative 1 and Oxycodone. Pain [MG30-MG3Z] [22]
Trimethadione DM0Q8MZ Moderate Antagonize the effect of Citalopram derivative 1 when combined with Trimethadione. Pancreatic cancer [2C10] [13]
Triclabendazole DMPWGBR Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Triclabendazole. Parasitic worm infestation [1F90] [7]
Safinamide DM0YWJC Moderate Additive serotonergic effects by the combination of Citalopram derivative 1 and Safinamide. Parkinsonism [8A00] [39]
Rasagiline DM3WKQ4 Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Rasagiline. Parkinsonism [8A00] [26]
Pimavanserin DMR7IVC Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Pimavanserin. Parkinsonism [8A00] [7]
Apomorphine DMX38HQ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Apomorphine. Parkinsonism [8A00] [7]
Abametapir DM2RX0I Moderate Decreased metabolism of Citalopram derivative 1 caused by Abametapir mediated inhibition of CYP450 enzyme. Pediculosis [1G00] [44]
Lindane DMB8CNL Moderate Increased risk of lowers seizure threshold by the combination of Citalopram derivative 1 and Lindane. Pediculosis [1G00] [45]
Esomeprazole DM7BN0X Major Decreased metabolism of Citalopram derivative 1 caused by Esomeprazole mediated inhibition of CYP450 enzyme. Peptic ulcer [DA61] [18]
Famotidine DMRL3AB Moderate Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Famotidine. Peptic ulcer [DA61] [9]
Macimorelin DMQYJIR Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Macimorelin. Pituitary gland disorder [5A60-5A61] [46]
Lefamulin DME6G97 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Lefamulin. Pneumonia [CA40] [7]
Choline salicylate DM8P137 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Choline salicylate. Postoperative inflammation [1A00-CA43] [10]
Ketorolac DMI4EL5 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Ketorolac. Postoperative inflammation [1A00-CA43] [10]
Bromfenac DMKB79O Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Bromfenac. Postoperative inflammation [1A00-CA43] [10]
Lonafarnib DMGM2Z6 Major Decreased metabolism of Citalopram derivative 1 caused by Lonafarnib mediated inhibition of CYP450 enzyme. Premature ageing appearance [LD2B] [18]
Ritodrine DM4V6RL Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ritodrine. Preterm labour/delivery [JB00] [15]
Degarelix DM3O8QY Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Degarelix. Prostate cancer [2C82] [7]
ABIRATERONE DM8V75C Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and ABIRATERONE. Prostate cancer [2C82] [7]
Nilutamide DMFN07X Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Nilutamide. Prostate cancer [2C82] [7]
Enzalutamide DMGL19D Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Enzalutamide. Prostate cancer [2C82] [7]
Relugolix DMK7IWL Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Relugolix. Prostate cancer [2C82] [7]
Bicalutamide DMZMSPF Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Bicalutamide. Prostate cancer [2C82] [7]
Levomepromazine DMIKFEL Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Levomepromazine. Psychotic disorder [6A20-6A25] [7]
Fluphenazine DMIT8LX Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Fluphenazine. Psychotic disorder [6A20-6A25] [7]
Triflupromazine DMKFQJP Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Triflupromazine. Psychotic disorder [6A20-6A25] [7]
Treprostinil DMTIQF3 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Treprostinil. Pulmonary hypertension [BB01] [10]
Epoprostenol DMUTYR2 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Epoprostenol. Pulmonary hypertension [BB01] [10]
Iloprost DMVPZBE Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Iloprost. Pulmonary hypertension [BB01] [10]
Temsirolimus DMS104F Moderate Increased plasma concentrations of Citalopram derivative 1 and Temsirolimus due to competitive inhibition of the same metabolic pathway. Renal cell carcinoma [2C90] [47]
Sorafenib DMS8IFC Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Sorafenib. Renal cell carcinoma [2C90] [7]
Gatifloxacin DMSL679 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Gatifloxacin. Respiratory infection [CA07-CA4Z] [7]
Meloxicam DM2AR7L Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Meloxicam. Rheumatoid arthritis [FA20] [10]
Sulindac DM2QHZU Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Sulindac. Rheumatoid arthritis [FA20] [10]
Celecoxib DM6LOQU Moderate Decreased metabolism of Citalopram derivative 1 caused by Celecoxib mediated inhibition of CYP450 enzyme. Rheumatoid arthritis [FA20] [48]
Oxaprozin DM9UB0P Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Oxaprozin. Rheumatoid arthritis [FA20] [10]
Flurbiprofen DMGN4BY Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Flurbiprofen. Rheumatoid arthritis [FA20] [10]
Fenoprofen DML5VQ0 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Fenoprofen. Rheumatoid arthritis [FA20] [10]
Indomethacin DMSC4A7 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Indomethacin. Rheumatoid arthritis [FA20] [10]
Tolmetin DMWUIJE Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Tolmetin. Rheumatoid arthritis [FA20] [10]
Quetiapine DM1N62C Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Quetiapine. Schizophrenia [6A20] [7]
Mesoridazine DM2ZGAN Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Mesoridazine. Schizophrenia [6A20] [7]
Thioridazine DM35M8J Major Decreased metabolism of Citalopram derivative 1 caused by Thioridazine mediated inhibition of CYP450 enzyme. Schizophrenia [6A20] [49]
Aripiprazole DM3NUMH Moderate Decreased metabolism of Citalopram derivative 1 caused by Aripiprazole mediated inhibition of CYP450 enzyme. Schizophrenia [6A20] [9]
Iloperidone DM6AUFY Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Iloperidone. Schizophrenia [6A20] [7]
Paliperidone DM7NPJS Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Paliperidone. Schizophrenia [6A20] [7]
Haloperidol DM96SE0 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Haloperidol. Schizophrenia [6A20] [7]
Perphenazine DMA4MRX Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Perphenazine. Schizophrenia [6A20] [7]
Chlorpromazine DMBGZI3 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Chlorpromazine. Schizophrenia [6A20] [7]
Clozapine DMFC71L Major Decreased metabolism of Citalopram derivative 1 caused by Clozapine mediated inhibition of CYP450 enzyme. Schizophrenia [6A20] [50]
Trifluoperazine DMKBYWI Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Trifluoperazine. Schizophrenia [6A20] [7]
Ziprasidone DMM58JY Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ziprasidone. Schizophrenia [6A20] [7]
Risperidone DMN6DXL Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Risperidone. Schizophrenia [6A20] [7]
Amisulpride DMSJVAM Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Amisulpride. Schizophrenia [6A20] [7]
Asenapine DMSQZE2 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Asenapine. Schizophrenia [6A20] [7]
Pimozide DMW83TP Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Pimozide. Schizophrenia [6A20] [7]
Salicyclic acid DM2F8XZ Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Salicyclic acid. Seborrhoeic dermatitis [EA81] [20]
Fentanyl DM8WAHT Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Fentanyl. Sensation disturbance [MB40] [12]
Sufentanil DMU7YEL Major Additive serotonergic effects by the combination of Citalopram derivative 1 and Sufentanil. Sensation disturbance [MB40] [12]
Vardenafil DMTBGW8 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Vardenafil. Sexual dysfunction [HA00-HA01] [7]
Voxelotor DMCS6M5 Minor Decreased metabolism of Citalopram derivative 1 caused by Voxelotor mediated inhibition of CYP450 enzyme. Sickle-cell disorder [3A51] [11]
Telotristat ethyl DMDIYFZ Moderate Increased metabolism of Citalopram derivative 1 caused by Telotristat ethyl mediated induction of CYP450 enzyme. Small intestine developmental anomaly [DA90] [32]
Larotrectinib DM26CQR Minor Decreased metabolism of Citalopram derivative 1 caused by Larotrectinib mediated inhibition of CYP450 enzyme. Solid tumour/cancer [2A00-2F9Z] [11]
Armodafinil DMGB035 Major Decreased metabolism of Citalopram derivative 1 caused by Armodafinil mediated inhibition of CYP450 enzyme. Solid tumour/cancer [2A00-2F9Z] [18]
Epirubicin DMPDW6T Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Epirubicin. Solid tumour/cancer [2A00-2F9Z] [7]
Vandetanib DMRICNP Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Vandetanib. Solid tumour/cancer [2A00-2F9Z] [7]
Triptorelin DMTK4LS Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Triptorelin. Solid tumour/cancer [2A00-2F9Z] [7]
Doxorubicin DMVP5YE Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Doxorubicin. Solid tumour/cancer [2A00-2F9Z] [7]
Pitolisant DM8RFNJ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Pitolisant. Somnolence [MG42] [7]
Telavancin DM58VQX Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Telavancin. Staphylococcal/streptococcal disease [1B5Y] [7]
Topiramate DM82Z30 Moderate Antagonize the effect of Citalopram derivative 1 when combined with Topiramate. Substance abuse [6C40] [13]
Warfarin DMJYCVW Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Warfarin. Supraventricular tachyarrhythmia [BC81] [10]
Ibutilide DMKXY2R Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Ibutilide. Supraventricular tachyarrhythmia [BC81] [7]
Adenosine DMM2NSK Major Increased risk of ventricular arrhythmias by the combination of Citalopram derivative 1 and Adenosine. Supraventricular tachyarrhythmia [BC81] [51]
Plicamycin DM7C8YV Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Plicamycin. Testicular cancer [2C80] [10]
Fostamatinib DM6AUHV Moderate Decreased clearance of Citalopram derivative 1 due to the transporter inhibition by Fostamatinib. Thrombocytopenia [3B64] [52]
Caplacizumab DMPUKA7 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Caplacizumab. Thrombocytopenia [3B64] [10]
Anagrelide DMSQ8MD Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Anagrelide. Thrombocytosis [3B63] [7]
Apixaban DM89JLN Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Apixaban. Thrombosis [DB61-GB90] [10]
Cangrelor DM8JRH0 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Cangrelor. Thrombosis [DB61-GB90] [10]
Brilinta DMBR01X Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Brilinta. Thrombosis [DB61-GB90] [10]
Argatroban DMFI46A Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Argatroban. Thrombosis [DB61-GB90] [10]
Dicumarol DMFQCB1 Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Dicumarol. Thrombosis [DB61-GB90] [20]
Clopidogrel DMOL54H Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Clopidogrel. Thrombosis [DB61-GB90] [10]
Lenvatinib DMB1IU4 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Lenvatinib. Thyroid cancer [2D10] [7]
Cabozantinib DMIYDT4 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Cabozantinib. Thyroid cancer [2D10] [7]
Papaverine DMCA9QP Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Papaverine. Tonus and reflex abnormality [MB47] [53]
Tizanidine DMR2IQ4 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Tizanidine. Tonus and reflex abnormality [MB47] [7]
Sirolimus DMGW1ID Moderate Increased plasma concentrations of Citalopram derivative 1 and Sirolimus due to competitive inhibition of the same metabolic pathway. Transplant rejection [NE84] [47]
Tacrolimus DMZ7XNQ Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Tacrolimus. Transplant rejection [NE84] [7]
Tolbutamide DM02AWV Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Tolbutamide. Type 2 diabetes mellitus [5A11] [5]
Chlorpropamide DMPHZQE Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Chlorpropamide. Type 2 diabetes mellitus [5A11] [5]
Insulin-detemir DMOA4VW Moderate Increased risk of hypoglycemia by the combination of Citalopram derivative 1 and Insulin-detemir. Type-1/2 diabete [5A10-5A11] [5]
Astemizole DM2HN6Q Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Astemizole. Vasomotor/allergic rhinitis [CA08] [7]
Trimeprazine DMEMV9D Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Trimeprazine. Vasomotor/allergic rhinitis [CA08] [7]
Cetirizine DMOMP9U Moderate Additive CNS depression effects by the combination of Citalopram derivative 1 and Cetirizine. Vasomotor/allergic rhinitis [CA08] [54]
Betrixaban DM2C4RF Moderate Increased risk of bleeding by the combination of Citalopram derivative 1 and Betrixaban. Venous thromboembolism [BD72] [10]
Disopyramide DM5SYZP Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Disopyramide. Ventricular tachyarrhythmia [BC71] [7]
Procainamide DMNMXR8 Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Procainamide. Ventricular tachyarrhythmia [BC71] [7]
Propafenone DMPIBJK Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Propafenone. Ventricular tachyarrhythmia [BC71] [7]
Flecainide DMSQDLE Major Increased risk of prolong QT interval by the combination of Citalopram derivative 1 and Flecainide. Ventricular tachyarrhythmia [BC71] [7]
⏷ Show the Full List of 402 DDI Information of This Drug

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