DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Cytochrome P450 3A4 (CYP3A4)
|
OTQGYY83
|
CP3A4_HUMAN
|
Increases Expression
|
[10] |
Cytochrome P450 1A1 (CYP1A1)
|
OTE4EFH8
|
CP1A1_HUMAN
|
Increases Expression
|
[29] |
Cytochrome P450 1A2 (CYP1A2)
|
OTLLBX48
|
CP1A2_HUMAN
|
Increases Expression
|
[29] |
Cytochrome P450 2C9 (CYP2C9)
|
OTGLBN29
|
CP2C9_HUMAN
|
Decreases Hydroxylation
|
[30] |
Cytochrome P450 2C19 (CYP2C19)
|
OTFMJYYE
|
CP2CJ_HUMAN
|
Increases Hydroxylation
|
[31] |
Cholesterol 24-hydroxylase (CYP46A1)
|
OTJ27FOX
|
CP46A_HUMAN
|
Increases Hydroxylation
|
[25] |
NAD(P)H dehydrogenase 1 (NQO1)
|
OTZGGIVK
|
NQO1_HUMAN
|
Increases Activity
|
[32] |
Solute carrier family 22 member 1 (SLC22A1)
|
OT7817I4
|
S22A1_HUMAN
|
Decreases Activity
|
[33] |
Solute carrier family 22 member 6 (SLC22A6)
|
OTKRCBVM
|
S22A6_HUMAN
|
Decreases Activity
|
[33] |
Organic anion transporter 7 (SLC22A9)
|
OTO4BJCC
|
S22A9_HUMAN
|
Decreases Activity
|
[33] |
Solute carrier family 22 member 11 (SLC22A11)
|
OTAJLNJZ
|
S22AB_HUMAN
|
Decreases Activity
|
[33] |
Solute carrier family 22 member 7 (SLC22A7)
|
OTKTNH1W
|
S22A7_HUMAN
|
Decreases Activity
|
[33] |
Prostaglandin G/H synthase 1 (PTGS1)
|
OTHCRLEC
|
PGH1_HUMAN
|
Decreases Activity
|
[34] |
Heme oxygenase 1 (HMOX1)
|
OTC1W6UX
|
HMOX1_HUMAN
|
Increases Expression
|
[9] |
Nuclear receptor subfamily 1 group I member 2 (NR1I2)
|
OTC5U0N5
|
NR1I2_HUMAN
|
Increases Expression
|
[10] |
Myc proto-oncogene protein (MYC)
|
OTPV5LUK
|
MYC_HUMAN
|
Increases Expression
|
[10] |
Protransforming growth factor alpha (TGFA)
|
OTPD1LL9
|
TGFA_HUMAN
|
Increases Expression
|
[10] |
Tumor necrosis factor (TNF)
|
OT4IE164
|
TNFA_HUMAN
|
Increases Expression
|
[10] |
Albumin (ALB)
|
OTVMM513
|
ALBU_HUMAN
|
Increases Expression
|
[10] |
Superoxide dismutase , mitochondrial (SOD2)
|
OTIWXGZ9
|
SODM_HUMAN
|
Increases Expression
|
[10] |
Fatty acid-binding protein, liver (FABP1)
|
OTR34ETM
|
FABPL_HUMAN
|
Decreases Expression
|
[10] |
Transcription factor JunD (JUND)
|
OTNKACJD
|
JUND_HUMAN
|
Increases Expression
|
[10] |
CCAAT/enhancer-binding protein beta (CEBPB)
|
OTM9MQIA
|
CEBPB_HUMAN
|
Increases Expression
|
[10] |
Phosphatidylcholine translocator ABCB4 (ABCB4)
|
OTE6PY83
|
MDR3_HUMAN
|
Decreases Expression
|
[10] |
G1/S-specific cyclin-D1 (CCND1)
|
OT8HPTKJ
|
CCND1_HUMAN
|
Increases Expression
|
[10] |
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)
|
OTDRV63V
|
GA45A_HUMAN
|
Increases Expression
|
[10] |
Cyclin-dependent kinase inhibitor 1 (CDKN1A)
|
OTQWHCZE
|
CDN1A_HUMAN
|
Increases Expression
|
[10] |
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)
|
OTI862QH
|
CPT1A_HUMAN
|
Increases Expression
|
[10] |
Adenosine kinase (ADK)
|
OTXR6VDI
|
ADK_HUMAN
|
Increases Expression
|
[10] |
Nuclear receptor subfamily 1 group I member 3 (NR1I3)
|
OTS3SGH7
|
NR1I3_HUMAN
|
Affects Expression
|
[10] |
ATP-binding cassette sub-family C member 2 (ABCC2)
|
OTJSIGV5
|
MRP2_HUMAN
|
Increases Expression
|
[10] |
CCN family member 1 (CCN1)
|
OTKJBEMD
|
CCN1_HUMAN
|
Increases Expression
|
[11] |
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3)
|
OTPGHZB9
|
IFIT3_HUMAN
|
Decreases Expression
|
[11] |
Toll-like receptor 2 (TLR2)
|
OTGO5P4R
|
TLR2_HUMAN
|
Decreases Expression
|
[11] |
Antiviral innate immune response receptor RIG-I (RIGI)
|
OTFIIC43
|
RIGI_HUMAN
|
Decreases Expression
|
[11] |
2'-5'-oligoadenylate synthase 1 (OAS1)
|
OT8ZLOCY
|
OAS1_HUMAN
|
Decreases Expression
|
[11] |
Ubiquitin-like protein ISG15 (ISG15)
|
OT53QQ7N
|
ISG15_HUMAN
|
Decreases Expression
|
[11] |
Interleukin-6 (IL6)
|
OTUOSCCU
|
IL6_HUMAN
|
Decreases Expression
|
[11] |
Asparagine synthetase (ASNS)
|
OT8R922G
|
ASNS_HUMAN
|
Decreases Expression
|
[11] |
Hepatocyte growth factor receptor (MET)
|
OT7K55MU
|
MET_HUMAN
|
Decreases Expression
|
[11] |
Steryl-sulfatase (STS)
|
OTXTJQPC
|
STS_HUMAN
|
Increases Expression
|
[11] |
Interferon alpha-inducible protein 6 (IFI6)
|
OTWOOAM4
|
IFI6_HUMAN
|
Decreases Expression
|
[11] |
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1)
|
OTXOQDSG
|
IFIT1_HUMAN
|
Decreases Expression
|
[11] |
Interferon-induced GTP-binding protein Mx1 (MX1)
|
OT6X8G5T
|
MX1_HUMAN
|
Decreases Expression
|
[11] |
Atypical chemokine receptor 3 (ACKR3)
|
OTA6GA4F
|
ACKR3_HUMAN
|
Decreases Expression
|
[11] |
Guanylate-binding protein 1 (GBP1)
|
OTUM7RPJ
|
GBP1_HUMAN
|
Decreases Expression
|
[11] |
Prostaglandin G/H synthase 2 (PTGS2)
|
OT75U9M4
|
PGH2_HUMAN
|
Decreases Expression
|
[11] |
Macrophage metalloelastase (MMP12)
|
OT9Z7LHM
|
MMP12_HUMAN
|
Decreases Expression
|
[11] |
Interferon alpha-inducible protein 27, mitochondrial (IFI27)
|
OTI2XGIT
|
IFI27_HUMAN
|
Decreases Expression
|
[11] |
Signal transducer and activator of transcription 1-alpha/beta (STAT1)
|
OTLMBUZ6
|
STAT1_HUMAN
|
Decreases Expression
|
[11] |
Regulator of G-protein signaling 4 (RGS4)
|
OTG94HHL
|
RGS4_HUMAN
|
Decreases Expression
|
[11] |
C-X-C chemokine receptor type 4 (CXCR4)
|
OTUFSBX2
|
CXCR4_HUMAN
|
Decreases Expression
|
[11] |
Interferon-induced 35 kDa protein (IFI35)
|
OTV9RZ53
|
IN35_HUMAN
|
Decreases Expression
|
[11] |
Signal transducer and activator of transcription 4 (STAT4)
|
OTAK3VFR
|
STAT4_HUMAN
|
Decreases Expression
|
[11] |
Bcl-2-related protein A1 (BCL2A1)
|
OTWRYSNA
|
B2LA1_HUMAN
|
Decreases Expression
|
[11] |
Lymphocyte antigen 6E (LY6E)
|
OTMG16BZ
|
LY6E_HUMAN
|
Decreases Expression
|
[11] |
Interferon-induced protein 44-like (IFI44L)
|
OTXKORJP
|
IF44L_HUMAN
|
Decreases Expression
|
[11] |
Olfactomedin-like protein 2B (OLFML2B)
|
OTDNJFR4
|
OLM2B_HUMAN
|
Increases Expression
|
[11] |
E3 ubiquitin-protein ligase RNF19B (RNF19B)
|
OTYCWKBP
|
RN19B_HUMAN
|
Decreases Expression
|
[11] |
Probable E3 ubiquitin-protein ligase HERC6 (HERC6)
|
OT7G9PQE
|
HERC6_HUMAN
|
Decreases Expression
|
[11] |
Interferon-induced protein 44 (IFI44)
|
OTOKSZVA
|
IFI44_HUMAN
|
Decreases Expression
|
[11] |
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (RSAD2)
|
OTCA9WCM
|
RSAD2_HUMAN
|
Decreases Expression
|
[11] |
Interferon regulatory factor 7 (IRF7)
|
OTC1A2PQ
|
IRF7_HUMAN
|
Decreases Expression
|
[11] |
Interferon-stimulated gene 20 kDa protein (ISG20)
|
OTCWRJJW
|
ISG20_HUMAN
|
Decreases Expression
|
[11] |
Latexin (LXN)
|
OTZQ2M6Y
|
LXN_HUMAN
|
Increases Expression
|
[11] |
Interferon-induced helicase C domain-containing protein 1 (IFIH1)
|
OTZA2AHA
|
IFIH1_HUMAN
|
Decreases Expression
|
[11] |
Interleukin-23 subunit alpha (IL23A)
|
OTYO99HC
|
IL23A_HUMAN
|
Decreases Expression
|
[11] |
Large neutral amino acids transporter small subunit 2 (SLC7A8)
|
OT8XXVO8
|
LAT2_HUMAN
|
Increases Expression
|
[11] |
E3 ISG15--protein ligase HERC5 (HERC5)
|
OTZ5PR39
|
HERC5_HUMAN
|
Decreases Expression
|
[11] |
Cystine/glutamate transporter (SLC7A11)
|
OTKJ6PXW
|
XCT_HUMAN
|
Decreases Expression
|
[11] |
Bile salt export pump (ABCB11)
|
OTRU7THO
|
ABCBB_HUMAN
|
Decreases Activity
|
[35] |
Prostaglandin reductase 1 (PTGR1)
|
OTMAR351
|
PTGR1_HUMAN
|
Decreases Activity
|
[36] |
Glutathione S-transferase A4 (GSTA4)
|
OTZ1USIA
|
GSTA4_HUMAN
|
Decreases Activity
|
[37] |
Glutathione S-transferase A1 (GSTA1)
|
OTA7K5XA
|
GSTA1_HUMAN
|
Decreases Activity
|
[37] |
Glutathione S-transferase P (GSTP1)
|
OTLP0A0Y
|
GSTP1_HUMAN
|
Affects Activity
|
[37] |
Glutathione S-transferase Mu 1 (GSTM1)
|
OTSBF2MO
|
GSTM1_HUMAN
|
Decreases Activity
|
[37] |
Glutathione S-transferase Mu 2 (GSTM2)
|
OTG4WT05
|
GSTM2_HUMAN
|
Decreases Activity
|
[37] |
Glutathione S-transferase Mu 4 (GSTM4)
|
OTOTF8DU
|
GSTM4_HUMAN
|
Affects Activity
|
[37] |
Glutathione S-transferase A3 (GSTA3)
|
OTJ3REE3
|
GSTA3_HUMAN
|
Decreases Activity
|
[37] |
Cytochrome P450 2E1 (CYP2E1)
|
OTHQ17JG
|
CP2E1_HUMAN
|
Decreases Activity
|
[38] |
Thymidine kinase 2, mitochondrial (TK2)
|
OTS1V4XB
|
KITM_HUMAN
|
Affects Expression
|
[13] |
DNA fragmentation factor subunit alpha (DFFA)
|
OTFPFMT8
|
DFFA_HUMAN
|
Affects Expression
|
[13] |
Cell division cycle 7-related protein kinase (CDC7)
|
OT5133XY
|
CDC7_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD)
|
OTOMP6TH
|
PK3CD_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PIK3C2A)
|
OTFBU4GD
|
P3C2A_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol 3-kinase regulatory subunit beta (PIK3R2)
|
OTZSUQK5
|
P85B_HUMAN
|
Affects Expression
|
[13] |
Suppressor of cytokine signaling 7 (SOCS7)
|
OT503VJG
|
SOCS7_HUMAN
|
Affects Expression
|
[13] |
Suppressor of cytokine signaling 6 (SOCS6)
|
OT2O5ZBK
|
SOCS6_HUMAN
|
Affects Expression
|
[13] |
Apoptotic protease-activating factor 1 (APAF1)
|
OTJWIVY0
|
APAF_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein kinase Chk1 (CHEK1)
|
OTTTI622
|
CHK1_HUMAN
|
Affects Expression
|
[13] |
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
|
OTA1CPBV
|
TR10B_HUMAN
|
Affects Expression
|
[13] |
Guanine nucleotide-binding protein subunit beta-5 (GNB5)
|
OT3ZSAXH
|
GNB5_HUMAN
|
Affects Expression
|
[13] |
DNA-directed RNA polymerase III subunit RPC1 (POLR3A)
|
OT5MSK10
|
RPC1_HUMAN
|
Affects Expression
|
[13] |
Ras-related protein M-Ras (MRAS)
|
OTNCVCQW
|
RASM_HUMAN
|
Affects Expression
|
[13] |
Transcription regulator protein BACH1 (BACH1)
|
OTY8004K
|
BACH1_HUMAN
|
Affects Expression
|
[13] |
Histone acetyltransferase type B catalytic subunit (HAT1)
|
OT307KEN
|
HAT1_HUMAN
|
Affects Expression
|
[13] |
Proepiregulin (EREG)
|
OTRM4NQY
|
EREG_HUMAN
|
Increases Expression
|
[39] |
Antizyme inhibitor 1 (AZIN1)
|
OTX5W77I
|
AZIN1_HUMAN
|
Affects Expression
|
[13] |
Mitogen-activated protein kinase 13 (MAPK13)
|
OT0W9GE7
|
MK13_HUMAN
|
Affects Expression
|
[13] |
Fanconi anemia group G protein (FANCG)
|
OT7MC8TZ
|
FANCG_HUMAN
|
Affects Expression
|
[13] |
Transmembrane protease serine 2 (TMPRSS2)
|
OTN44YQ5
|
TMPS2_HUMAN
|
Increases Expression
|
[40] |
ATP-binding cassette sub-family C member 4 (ABCC4)
|
OTO27PAL
|
MRP4_HUMAN
|
Affects Expression
|
[13] |
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2)
|
OTP45YKX
|
P4HA2_HUMAN
|
Increases Expression
|
[41] |
CASP8 and FADD-like apoptosis regulator (CFLAR)
|
OTX14BAS
|
CFLAR_HUMAN
|
Affects Expression
|
[13] |
3-phosphoinositide-dependent protein kinase 1 (PDPK1)
|
OTT09ZVP
|
PDPK1_HUMAN
|
Affects Expression
|
[13] |
Adenylate cyclase type 6 (ADCY6)
|
OTFOY4WW
|
ADCY6_HUMAN
|
Affects Expression
|
[13] |
Mitogen-activated protein kinase kinase kinase 7 (MAP3K7)
|
OTUXEASC
|
M3K7_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 4 gamma 3 (EIF4G3)
|
OTZCRXLJ
|
IF4G3_HUMAN
|
Affects Expression
|
[13] |
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1)
|
OTDTF5BU
|
SUV91_HUMAN
|
Affects Expression
|
[13] |
Bcl-2-like protein 11 (BCL2L11)
|
OTNQQWFJ
|
B2L11_HUMAN
|
Affects Expression
|
[13] |
Forkhead box protein O3 (FOXO3)
|
OTHXQG4P
|
FOXO3_HUMAN
|
Affects Expression
|
[13] |
Integral membrane protein 2A (ITM2A)
|
OT590V63
|
ITM2A_HUMAN
|
Increases Expression
|
[41] |
Mediator of RNA polymerase II transcription subunit 14 (MED14)
|
OTMD20XN
|
MED14_HUMAN
|
Affects Expression
|
[13] |
RNA helicase aquarius (AQR)
|
OTMNDXM1
|
AQR_HUMAN
|
Affects Expression
|
[13] |
Frizzled-6 (FZD6)
|
OTBCPII8
|
FZD6_HUMAN
|
Affects Expression
|
[13] |
Adenylate cyclase type 9 (ADCY9)
|
OT1IZT5K
|
ADCY9_HUMAN
|
Affects Expression
|
[13] |
DNA polymerase zeta catalytic subunit (REV3L)
|
OT0OP8EJ
|
REV3L_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily A member 2 (DNAJA2)
|
OTKF1VBT
|
DNJA2_HUMAN
|
Affects Expression
|
[13] |
Auxilin (DNAJC6)
|
OT1P6ZIE
|
AUXI_HUMAN
|
Affects Expression
|
[13] |
Frizzled-7 (FZD7)
|
OTTK3F6E
|
FZD7_HUMAN
|
Affects Expression
|
[13] |
Rho-associated protein kinase 2 (ROCK2)
|
OTVYN14T
|
ROCK2_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily B member 6 (DNAJB6)
|
OTMHIIAN
|
DNJB6_HUMAN
|
Affects Expression
|
[13] |
Nucleoside diphosphate phosphatase ENTPD5 (ENTPD5)
|
OTFH05B9
|
ENTP5_HUMAN
|
Affects Expression
|
[13] |
DNA polymerase theta (POLQ)
|
OTBHK0E6
|
DPOLQ_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1)
|
OTY9R6FZ
|
ERN1_HUMAN
|
Affects Expression
|
[13] |
Mediator of RNA polymerase II transcription subunit 6 (MED6)
|
OT4GF4RM
|
MED6_HUMAN
|
Affects Expression
|
[13] |
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)
|
OTYG179K
|
PR15A_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 8 (DNAJC8)
|
OTBE4I4X
|
DNJC8_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein kinase D3 (PRKD3)
|
OT987HJI
|
KPCD3_HUMAN
|
Affects Expression
|
[13] |
Dickkopf-related protein 1 (DKK1)
|
OTRDLUSP
|
DKK1_HUMAN
|
Affects Expression
|
[13] |
Epsin-2 (EPN2)
|
OTH5BHUN
|
EPN2_HUMAN
|
Affects Expression
|
[13] |
Neuroendocrine secretory protein 55 (GNAS)
|
OTMH8BKJ
|
GNAS3_HUMAN
|
Affects Expression
|
[13] |
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)
|
OTBMJUOC
|
M4K4_HUMAN
|
Affects Expression
|
[13] |
Apoptosis-inducing factor 1, mitochondrial (AIFM1)
|
OTKPWB7Q
|
AIFM1_HUMAN
|
Affects Expression
|
[13] |
Formimidoyltransferase-cyclodeaminase (FTCD)
|
OTX9HZT5
|
FTCD_HUMAN
|
Affects Expression
|
[13] |
G1/S-specific cyclin-E2 (CCNE2)
|
OTBBUKQQ
|
CCNE2_HUMAN
|
Affects Expression
|
[13] |
Dihydrofolate reductase (DHFR)
|
OT3DVIGM
|
DYR_HUMAN
|
Affects Expression
|
[13] |
Superoxide dismutase (SOD1)
|
OT39TA1L
|
SODC_HUMAN
|
Increases Expression
|
[42] |
Protein c-Fos (FOS)
|
OTJBUVWS
|
FOS_HUMAN
|
Increases Expression
|
[43] |
GTPase NRas (NRAS)
|
OTVQ1DG3
|
RASN_HUMAN
|
Affects Expression
|
[13] |
GTPase HRas (HRAS)
|
OTWQN0DP
|
RASH_HUMAN
|
Affects Expression
|
[13] |
GTPase KRas (KRAS)
|
OT78QCN8
|
RASK_HUMAN
|
Affects Expression
|
[13] |
Interleukin-1 alpha (IL1A)
|
OTPSGILV
|
IL1A_HUMAN
|
Increases Expression
|
[39] |
Interleukin-1 beta (IL1B)
|
OT0DWXXB
|
IL1B_HUMAN
|
Increases Expression
|
[44] |
Erythropoietin (EPO)
|
OTZ90CN4
|
EPO_HUMAN
|
Affects Expression
|
[13] |
HLA class II histocompatibility antigen, DRB1 beta chain (HLA-DRB1)
|
OTRGGIFP
|
DRB1_HUMAN
|
Affects Expression
|
[45] |
Estrogen receptor (ESR1)
|
OTKLU61J
|
ESR1_HUMAN
|
Affects Activity
|
[46] |
Antileukoproteinase (SLPI)
|
OTUNFUU8
|
SLPI_HUMAN
|
Increases Expression
|
[39] |
Glucocorticoid receptor (NR3C1)
|
OTCI2YDI
|
GCR_HUMAN
|
Affects Expression
|
[13] |
Thymidine kinase, cytosolic (TK1)
|
OTY5JFM1
|
KITH_HUMAN
|
Affects Expression
|
[13] |
Argininosuccinate lyase (ASL)
|
OTI2NGQR
|
ARLY_HUMAN
|
Affects Expression
|
[13] |
Cellular tumor antigen p53 (TP53)
|
OTIE1VH3
|
P53_HUMAN
|
Increases Expression
|
[42] |
Protein S100-A8 (S100A8)
|
OTVMOB3F
|
S10A8_HUMAN
|
Increases Expression
|
[47] |
Plasminogen activator inhibitor 1 (SERPINE1)
|
OTT0MPQ3
|
PAI1_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1)
|
OTM0GDTP
|
IF2A_HUMAN
|
Affects Expression
|
[13] |
Intercellular adhesion molecule 1 (ICAM1)
|
OTTOIX77
|
ICAM1_HUMAN
|
Affects Expression
|
[13] |
Transcription factor Jun (JUN)
|
OTCYBO6X
|
JUN_HUMAN
|
Affects Expression
|
[13] |
DNA-directed RNA polymerase III subunit RPC4 (POLR3D)
|
OTXQTBS0
|
RPC4_HUMAN
|
Affects Expression
|
[13] |
Integrin beta-1 (ITGB1)
|
OT6G1IAR
|
ITB1_HUMAN
|
Affects Expression
|
[13] |
Insulin receptor (INSR)
|
OTTY341H
|
INSR_HUMAN
|
Affects Expression
|
[13] |
Retinoblastoma-associated protein (RB1)
|
OTQJUJMZ
|
RB_HUMAN
|
Affects Expression
|
[13] |
Protein S100-A9 (S100A9)
|
OTOARHCS
|
S10A9_HUMAN
|
Increases Expression
|
[47] |
Glutathione peroxidase 1 (GPX1)
|
OTE2O72Q
|
GPX1_HUMAN
|
Increases Expression
|
[42] |
Insulin-like growth factor 1 receptor (IGF1R)
|
OTXJIF13
|
IGF1R_HUMAN
|
Affects Expression
|
[13] |
Insulin-like growth factor-binding protein 1 (IGFBP1)
|
OT6UQV2K
|
IBP1_HUMAN
|
Affects Expression
|
[13] |
High mobility group protein B1 (HMGB1)
|
OT4B7CPF
|
HMGB1_HUMAN
|
Affects Expression
|
[13] |
Poly polymerase 1 (PARP1)
|
OT310QSG
|
PARP1_HUMAN
|
Affects Expression
|
[13] |
Calmodulin-1 (CALM2)
|
OTNYA92F
|
CALM1_HUMAN
|
Affects Expression
|
[13] |
Interleukin-8 (CXCL8)
|
OTS7T5VH
|
IL8_HUMAN
|
Increases Expression
|
[48] |
Androgen receptor (AR)
|
OTUBKAZZ
|
ANDR_HUMAN
|
Affects Activity
|
[46] |
Serine/threonine-protein kinase A-Raf (ARAF)
|
OTZJ0FNO
|
ARAF_HUMAN
|
Affects Expression
|
[13] |
Apoptosis regulator Bcl-2 (BCL2)
|
OT9DVHC0
|
BCL2_HUMAN
|
Increases Expression
|
[42] |
Nuclear receptor subfamily 2 group F member 6 (NR2F6)
|
OTNVO2B6
|
NR2F6_HUMAN
|
Affects Expression
|
[13] |
COUP transcription factor 1 (NR2F1)
|
OTGWZWYL
|
COT1_HUMAN
|
Affects Expression
|
[13] |
Endoplasmic reticulum chaperone BiP (HSPA5)
|
OTFUIRAO
|
BIP_HUMAN
|
Increases Expression
|
[49] |
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (DBT)
|
OT4KZ5R9
|
ODB2_HUMAN
|
Affects Expression
|
[13] |
Fibroblast growth factor receptor 1 (FGFR1)
|
OT4GLCXW
|
FGFR1_HUMAN
|
Affects Expression
|
[13] |
Proliferating cell nuclear antigen (PCNA)
|
OTHZ1RIA
|
PCNA_HUMAN
|
Affects Expression
|
[50] |
Bone morphogenetic protein 4 (BMP4)
|
OTPZMDFH
|
BMP4_HUMAN
|
Affects Expression
|
[13] |
Cadherin-1 (CDH1)
|
OTFJMXPM
|
CADH1_HUMAN
|
Increases Expression
|
[12] |
Proto-oncogene tyrosine-protein kinase Src (SRC)
|
OTETYX40
|
SRC_HUMAN
|
Affects Expression
|
[13] |
C-C motif chemokine 2 (CCL2)
|
OTAD2HEL
|
CCL2_HUMAN
|
Increases Expression
|
[48] |
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2)
|
OT1LQSGX
|
MTDC_HUMAN
|
Affects Expression
|
[13] |
L-selectin (SELL)
|
OT6RAJZR
|
LYAM1_HUMAN
|
Decreases Expression
|
[51] |
Interleukin-1 receptor type 1 (IL1R1)
|
OTTU8959
|
IL1R1_HUMAN
|
Affects Expression
|
[13] |
POU domain, class 2, transcription factor 1 (POU2F1)
|
OTK7ELJ0
|
PO2F1_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein kinase B-raf (BRAF)
|
OT7S81XQ
|
BRAF_HUMAN
|
Affects Expression
|
[13] |
Cyclic AMP-dependent transcription factor ATF-2 (ATF2)
|
OTNIZPEA
|
ATF2_HUMAN
|
Affects Expression
|
[13] |
15-hydroxyprostaglandin dehydrogenase (HPGD)
|
OTYZI6JB
|
PGDH_HUMAN
|
Increases Expression
|
[52] |
Transcription factor E2-alpha (TCF3)
|
OTW6FR32
|
TFE2_HUMAN
|
Affects Expression
|
[13] |
Replication protein A 32 kDa subunit (RPA2)
|
OTZ54WAF
|
RFA2_HUMAN
|
Affects Expression
|
[13] |
Histone H2AX (H2AX)
|
OT18UX57
|
H2AX_HUMAN
|
Increases Expression
|
[53] |
Carbonyl reductase 1 (CBR1)
|
OTQ3A541
|
CBR1_HUMAN
|
Affects Expression
|
[13] |
Tyrosine-protein kinase Fer (FER)
|
OT9JR7AE
|
FER_HUMAN
|
Affects Expression
|
[13] |
Stathmin (STMN1)
|
OTDJ4RV0
|
STMN1_HUMAN
|
Affects Expression
|
[13] |
Rho-related GTP-binding protein RhoQ (RHOQ)
|
OTUBTU57
|
RHOQ_HUMAN
|
Affects Expression
|
[13] |
Aspartate aminotransferase, cytoplasmic (GOT1)
|
OTZLM5UB
|
AATC_HUMAN
|
Increases Secretion
|
[54] |
Protein kinase C alpha type (PRKCA)
|
OT5UWNRD
|
KPCA_HUMAN
|
Affects Expression
|
[13] |
Integrin alpha-2 (ITGA2)
|
OTPFL017
|
ITA2_HUMAN
|
Affects Expression
|
[13] |
CTP synthase 1 (CTPS1)
|
OTZ9J6ZG
|
PYRG1_HUMAN
|
Affects Expression
|
[13] |
Probable ATP-dependent RNA helicase DDX5 (DDX5)
|
OTLS124U
|
DDX5_HUMAN
|
Affects Expression
|
[13] |
Insulin-like growth factor-binding protein 3 (IGFBP3)
|
OTIX63TX
|
IBP3_HUMAN
|
Affects Expression
|
[13] |
Early growth response protein 1 (EGR1)
|
OTCP6XGZ
|
EGR1_HUMAN
|
Increases Expression
|
[55] |
Glutathione peroxidase 2 (GPX2)
|
OTXI2NTI
|
GPX2_HUMAN
|
Affects Expression
|
[13] |
Interleukin-1 receptor antagonist protein (IL1RN)
|
OT308CBE
|
IL1RA_HUMAN
|
Increases Expression
|
[56] |
Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
|
OTRFV19J
|
ATF4_HUMAN
|
Increases Expression
|
[13] |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1)
|
OTSBQR6D
|
PLCG1_HUMAN
|
Affects Expression
|
[13] |
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)
|
OT2D9DOV
|
TNR1A_HUMAN
|
Affects Expression
|
[13] |
Casein kinase II subunit alpha' (CSNK2A2)
|
OT7MA2LV
|
CSK22_HUMAN
|
Affects Expression
|
[13] |
Nuclear factor NF-kappa-B p105 subunit (NFKB1)
|
OTNRRD8I
|
NFKB1_HUMAN
|
Decreases Expression
|
[42] |
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2)
|
OTXF0B09
|
IF2B_HUMAN
|
Affects Expression
|
[13] |
Hepatocyte nuclear factor 1-alpha (HNF1A)
|
OT9DOUKL
|
HNF1A_HUMAN
|
Affects Expression
|
[13] |
Ras GTPase-activating protein 1 (RASA1)
|
OTZJ3LP4
|
RASA1_HUMAN
|
Affects Expression
|
[13] |
Amine oxidase A (MAOA)
|
OT8NIWMQ
|
AOFA_HUMAN
|
Affects Expression
|
[13] |
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)
|
OTVLI4DD
|
TNAP3_HUMAN
|
Decreases Expression
|
[57] |
Diamine acetyltransferase 1 (SAT1)
|
OT52AU22
|
SAT1_HUMAN
|
Affects Expression
|
[13] |
Bone morphogenetic protein 6 (BMP6)
|
OT9WN536
|
BMP6_HUMAN
|
Increases Expression
|
[39] |
Trifunctional purine biosynthetic protein adenosine-3 (GART)
|
OT01JWJB
|
PUR2_HUMAN
|
Affects Expression
|
[13] |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1)
|
OT3MPPYX
|
ENPP1_HUMAN
|
Affects Expression
|
[13] |
5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS2)
|
OTJXOUCL
|
HEM0_HUMAN
|
Affects Expression
|
[13] |
E3 ubiquitin-protein ligase CBL (CBL)
|
OTTKELCU
|
CBL_HUMAN
|
Affects Expression
|
[13] |
cAMP-dependent protein kinase catalytic subunit beta (PRKACB)
|
OT6RMDCE
|
KAPCB_HUMAN
|
Affects Expression
|
[13] |
Glycine dehydrogenase (GLDC)
|
OTVVDNW0
|
GCSP_HUMAN
|
Affects Expression
|
[13] |
Thymidylate kinase (DTYMK)
|
OTJXYQYK
|
KTHY_HUMAN
|
Affects Expression
|
[13] |
Alanine aminotransferase 1 (GPT)
|
OTOXOA0Q
|
ALAT1_HUMAN
|
Increases Secretion
|
[54] |
COUP transcription factor 2 (NR2F2)
|
OTJFS67N
|
COT2_HUMAN
|
Affects Expression
|
[13] |
G1/S-specific cyclin-E1 (CCNE1)
|
OTLD7UID
|
CCNE1_HUMAN
|
Affects Expression
|
[13] |
Cyclin-dependent kinase 2 (CDK2)
|
OTB5DYYZ
|
CDK2_HUMAN
|
Affects Expression
|
[13] |
Tumor necrosis factor receptor superfamily member 6 (FAS)
|
OTP9XG86
|
TNR6_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily B member 1 (DNAJB1)
|
OTCOSEVH
|
DNJB1_HUMAN
|
Affects Expression
|
[13] |
Amine oxidase B (MAOB)
|
OTTDFM1O
|
AOFB_HUMAN
|
Affects Expression
|
[13] |
Mitogen-activated protein kinase 3 (MAPK3)
|
OTCYKGKO
|
MK03_HUMAN
|
Increases Phosphorylation
|
[48] |
Aryl hydrocarbon receptor nuclear translocator (ARNT)
|
OTMSIEZY
|
ARNT_HUMAN
|
Affects Expression
|
[13] |
Replication protein A 70 kDa DNA-binding subunit (RPA1)
|
OT76POLP
|
RFA1_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1)
|
OT5BZ1J9
|
P85A_HUMAN
|
Affects Expression
|
[13] |
Mitogen-activated protein kinase 1 (MAPK1)
|
OTH85PI5
|
MK01_HUMAN
|
Increases Phosphorylation
|
[48] |
Dual specificity protein phosphatase 1 (DUSP1)
|
OTN6BR75
|
DUS1_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B)
|
OTFIHQGD
|
2AAB_HUMAN
|
Affects Expression
|
[13] |
G1/S-specific cyclin-D3 (CCND3)
|
OTNKPQ22
|
CCND3_HUMAN
|
Affects Expression
|
[13] |
Glutathione S-transferase theta-1 (GSTT1)
|
OTRFMWBK
|
GSTT1_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily A member 1 (DNAJA1)
|
OT38BZQQ
|
DNJA1_HUMAN
|
Affects Expression
|
[13] |
RAC-alpha serine/threonine-protein kinase (AKT1)
|
OT8H2YY7
|
AKT1_HUMAN
|
Affects Expression
|
[13] |
RAC-beta serine/threonine-protein kinase (AKT2)
|
OTBB632K
|
AKT2_HUMAN
|
Affects Expression
|
[13] |
14-3-3 protein sigma (SFN)
|
OTLJCZ1U
|
1433S_HUMAN
|
Increases Expression
|
[41] |
Cystathionine gamma-lyase (CTH)
|
OTC90LA0
|
CGL_HUMAN
|
Affects Expression
|
[13] |
Cleavage stimulation factor subunit 2 (CSTF2)
|
OTR6G4II
|
CSTF2_HUMAN
|
Affects Expression
|
[13] |
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT)
|
OT0THBVA
|
DUT_HUMAN
|
Affects Expression
|
[13] |
DNA replication licensing factor MCM7 (MCM7)
|
OT6FXC6K
|
MCM7_HUMAN
|
Affects Expression
|
[13] |
Serine hydroxymethyltransferase, cytosolic (SHMT1)
|
OTIINA3J
|
GLYC_HUMAN
|
Affects Expression
|
[13] |
Catenin beta-1 (CTNNB1)
|
OTZ932A3
|
CTNB1_HUMAN
|
Affects Expression
|
[13] |
Nitric oxide synthase, inducible (NOS2)
|
OTKKIOJ1
|
NOS2_HUMAN
|
Decreases Expression
|
[42] |
Cystathionine beta-synthase (CBS)
|
OT46FSKD
|
CBS_HUMAN
|
Affects Expression
|
[13] |
Phosphoenolpyruvate carboxykinase, cytosolic (PCK1)
|
OTNWEJ5Y
|
PCKGC_HUMAN
|
Affects Expression
|
[13] |
Insulin receptor substrate 1 (IRS1)
|
OTNO82CU
|
IRS1_HUMAN
|
Affects Expression
|
[13] |
DNA damage-inducible transcript 3 protein (DDIT3)
|
OTI8YKKE
|
DDIT3_HUMAN
|
Increases Expression
|
[13] |
Choline kinase alpha (CHKA)
|
OT7FVO3Z
|
CHKA_HUMAN
|
Affects Expression
|
[13] |
Activin receptor type-1B (ACVR1B)
|
OT778HIQ
|
ACV1B_HUMAN
|
Affects Expression
|
[13] |
Peroxisome proliferator-activated receptor gamma (PPARG)
|
OTHMARHO
|
PPARG_HUMAN
|
Increases Activity
|
[58] |
Signal transducer and activator of transcription 3 (STAT3)
|
OTAAGKYZ
|
STAT3_HUMAN
|
Increases Expression
|
[50] |
Cyclin-F (CCNF)
|
OTJFVU43
|
CCNF_HUMAN
|
Affects Expression
|
[13] |
Glycine--tRNA ligase (GARS1)
|
OT5B6R9Y
|
GARS_HUMAN
|
Affects Expression
|
[13] |
Reduced folate transporter (SLC19A1)
|
OTWB0BTO
|
S19A1_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 1 (EIF1)
|
OTB4GZ0V
|
EIF1_HUMAN
|
Affects Expression
|
[13] |
Protein kinase C iota type (PRKCI)
|
OTKBAVT3
|
KPCI_HUMAN
|
Affects Expression
|
[13] |
Signal transducer and activator of transcription 6 (STAT6)
|
OTCKMP49
|
STAT6_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA)
|
OTTOMI8J
|
PK3CA_HUMAN
|
Affects Expression
|
[13] |
Caspase-3 (CASP3)
|
OTIJRBE7
|
CASP3_HUMAN
|
Increases Activity
|
[59] |
Caspase-2 (CASP2)
|
OTUDYSPP
|
CASP2_HUMAN
|
Affects Expression
|
[13] |
Tyrosine-protein kinase ABL2 (ABL2)
|
OTS8F4GD
|
ABL2_HUMAN
|
Affects Expression
|
[13] |
Transcription factor GATA-4 (GATA4)
|
OTQHWAZG
|
GATA4_HUMAN
|
Affects Expression
|
[13] |
Mitogen-activated protein kinase 8 (MAPK8)
|
OTEREYS5
|
MK08_HUMAN
|
Affects Expression
|
[13] |
Cyclin-dependent kinase inhibitor 1B (CDKN1B)
|
OTNY5LLZ
|
CDN1B_HUMAN
|
Affects Expression
|
[13] |
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3)
|
OTI2OREX
|
MP2K3_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX)
|
OTWG2LAB
|
IF1AX_HUMAN
|
Affects Expression
|
[13] |
Glutamate--cysteine ligase catalytic subunit (GCLC)
|
OTESDI4D
|
GSH1_HUMAN
|
Affects Expression
|
[13] |
Glutamate--cysteine ligase regulatory subunit (GCLM)
|
OT6CP234
|
GSH0_HUMAN
|
Affects Expression
|
[13] |
Serine--tRNA ligase, cytoplasmic (SARS1)
|
OTFKXQ1O
|
SYSC_HUMAN
|
Affects Expression
|
[13] |
Glycogen synthase kinase-3 beta (GSK3B)
|
OTL3L14B
|
GSK3B_HUMAN
|
Affects Expression
|
[13] |
Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ)
|
OTOODWTU
|
GNAQ_HUMAN
|
Affects Expression
|
[13] |
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 (GNG4)
|
OTOXNDI9
|
GBG4_HUMAN
|
Affects Expression
|
[13] |
Cyclin-dependent kinase 7 (CDK7)
|
OTAO19PQ
|
CDK7_HUMAN
|
Affects Expression
|
[13] |
Signal transducer and activator of transcription 5B (STAT5B)
|
OTZVPEBT
|
STA5B_HUMAN
|
Affects Expression
|
[13] |
Cyclin-H (CCNH)
|
OTKDU3SR
|
CCNH_HUMAN
|
Affects Expression
|
[13] |
Dual specificity mitogen-activated protein kinase kinase 6 (MAP2K6)
|
OTK13JKC
|
MP2K6_HUMAN
|
Affects Expression
|
[13] |
DNA polymerase subunit gamma-1 (POLG)
|
OTDUCT04
|
DPOG1_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 5 (EIF5)
|
OT79PQUN
|
IF5_HUMAN
|
Affects Expression
|
[13] |
Caspase-9 (CASP9)
|
OTD4RFFG
|
CASP9_HUMAN
|
Increases Expression
|
[42] |
Caspase-6 (CASP6)
|
OTXLD3EC
|
CASP6_HUMAN
|
Affects Expression
|
[13] |
Hepatocyte nuclear factor 3-alpha (FOXA1)
|
OTEBY0TD
|
FOXA1_HUMAN
|
Affects Expression
|
[13] |
Tumor protein D52 (TPD52)
|
OTPKSK43
|
TPD52_HUMAN
|
Increases Expression
|
[57] |
Eukaryotic translation initiation factor 3 subunit B (EIF3B)
|
OTF67VPH
|
EIF3B_HUMAN
|
Affects Expression
|
[13] |
BH3-interacting domain death agonist (BID)
|
OTOSHSHU
|
BID_HUMAN
|
Increases Activity
|
[60] |
C-terminal-binding protein 2 (CTBP2)
|
OTGZGT87
|
CTBP2_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)
|
OTOWDUNT
|
PTEN_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic initiation factor 4A-I (EIF4A1)
|
OTMTBX6N
|
IF4A1_HUMAN
|
Affects Expression
|
[13] |
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (POLR2F)
|
OTF9T8I2
|
RPAB2_HUMAN
|
Affects Expression
|
[13] |
Transforming growth factor beta-2 proprotein (TGFB2)
|
OTC0TXEP
|
TGFB2_HUMAN
|
Decreases Expression
|
[41] |
Ras-related protein R-Ras2 (RRAS2)
|
OT83NCEB
|
RRAS2_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB)
|
OTYFTYFR
|
PP1B_HUMAN
|
Affects Expression
|
[13] |
Rho-related GTP-binding protein RhoB (RHOB)
|
OTHQFQF7
|
RHOB_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A)
|
OT9297OG
|
2ABA_HUMAN
|
Affects Expression
|
[13] |
Small ribosomal subunit protein RACK1 (RACK1)
|
OTZBCQ1U
|
RACK1_HUMAN
|
Affects Expression
|
[13] |
Actin, alpha skeletal muscle (ACTA1)
|
OTOVGLPG
|
ACTS_HUMAN
|
Affects Expression
|
[13] |
Casein kinase II subunit alpha (CSNK2A1)
|
OT9T8WQM
|
CSK21_HUMAN
|
Affects Expression
|
[13] |
ETS-related transcription factor Elf-3 (ELF3)
|
OTUTLEQO
|
ELF3_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol-glycan-specific phospholipase D (GPLD1)
|
OTUUQOVY
|
PHLD_HUMAN
|
Affects Expression
|
[13] |
Cytochrome c (CYCS)
|
OTBFALJD
|
CYC_HUMAN
|
Affects Expression
|
[13] |
Cyclin-dependent kinase 6 (CDK6)
|
OTR95N0X
|
CDK6_HUMAN
|
Affects Expression
|
[13] |
Cyclin-dependent kinase 5 (CDK5)
|
OT1YAK9F
|
CDK5_HUMAN
|
Affects Expression
|
[13] |
Fanconi anemia group C protein (FANCC)
|
OTTIDM3P
|
FANCC_HUMAN
|
Affects Expression
|
[13] |
Heat shock factor protein 1 (HSF1)
|
OTYNJ4KP
|
HSF1_HUMAN
|
Increases Activity
|
[61] |
Transcription factor E2F1 (E2F1)
|
OTLKYBBC
|
E2F1_HUMAN
|
Affects Expression
|
[13] |
Myocyte-specific enhancer factor 2A (MEF2A)
|
OTV2SF6E
|
MEF2A_HUMAN
|
Affects Expression
|
[13] |
Cytochrome P450 4A11 (CYP4A11)
|
OTPU5J0S
|
CP4AB_HUMAN
|
Affects Activity
|
[62] |
Transcription factor p65 (RELA)
|
OTUJP9CN
|
TF65_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1)
|
OT2CF1E6
|
IF4G1_HUMAN
|
Affects Expression
|
[13] |
Activin receptor type-1 (ACVR1)
|
OT4JATFE
|
ACVR1_HUMAN
|
Affects Expression
|
[13] |
Max dimerization protein 1 (MXD1)
|
OTS5CTHX
|
MAD1_HUMAN
|
Affects Expression
|
[13] |
Focal adhesion kinase 1 (PTK2)
|
OT3Q1JDY
|
FAK1_HUMAN
|
Affects Expression
|
[13] |
DNA repair protein RAD51 homolog 1 (RAD51)
|
OTNVWGC1
|
RAD51_HUMAN
|
Affects Expression
|
[13] |
Tight junction protein ZO-1 (TJP1)
|
OTBDCUPK
|
ZO1_HUMAN
|
Affects Expression
|
[13] |
Apoptosis regulator BAX (BAX)
|
OTAW0V4V
|
BAX_HUMAN
|
Increases Expression
|
[42] |
Bcl-2-like protein 1 (BCL2L1)
|
OTRC5K9O
|
B2CL1_HUMAN
|
Increases Expression
|
[63] |
Son of sevenless homolog 1 (SOS1)
|
OTTCWXC3
|
SOS1_HUMAN
|
Affects Expression
|
[13] |
Son of sevenless homolog 2 (SOS2)
|
OTV3XRE5
|
SOS2_HUMAN
|
Affects Expression
|
[13] |
Epithelial discoidin domain-containing receptor 1 (DDR1)
|
OTYW1SH8
|
DDR1_HUMAN
|
Affects Expression
|
[13] |
Forkhead box protein O1 (FOXO1)
|
OTPJRB6D
|
FOXO1_HUMAN
|
Affects Expression
|
[13] |
Cleavage stimulation factor subunit 3 (CSTF3)
|
OT1Y7B5U
|
CSTF3_HUMAN
|
Affects Expression
|
[13] |
Interleukin-24 (IL24)
|
OT4VUWH1
|
IL24_HUMAN
|
Increases Expression
|
[39] |
Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5)
|
OT6T408U
|
MP2K5_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein kinase PAK 2 (PAK2)
|
OTLUNCIH
|
PAK2_HUMAN
|
Affects Expression
|
[13] |
Growth factor receptor-bound protein 10 (GRB10)
|
OTCKXGRC
|
GRB10_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PPP2R5C)
|
OTF7CGO2
|
2A5G_HUMAN
|
Affects Expression
|
[13] |
Rho-associated protein kinase 1 (ROCK1)
|
OTSXYVW1
|
ROCK1_HUMAN
|
Affects Expression
|
[13] |
Frizzled-5 (FZD5)
|
OTXFFY56
|
FZD5_HUMAN
|
Affects Expression
|
[13] |
GRB2-associated-binding protein 1 (GAB1)
|
OTQKE6V4
|
GAB1_HUMAN
|
Affects Expression
|
[13] |
Mothers against decapentaplegic homolog 4 (SMAD4)
|
OTWQWCKG
|
SMAD4_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)
|
OTHBQVD5
|
4EBP1_HUMAN
|
Affects Expression
|
[13] |
Cullin-3 (CUL3)
|
OTDNOAPM
|
CUL3_HUMAN
|
Affects Expression
|
[13] |
Activin receptor type-2B (ACVR2B)
|
OT209XLA
|
AVR2B_HUMAN
|
Affects Expression
|
[13] |
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD)
|
OT5UO1FA
|
HNRPD_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 3 subunit A (EIF3A)
|
OTFABY9G
|
EIF3A_HUMAN
|
Affects Expression
|
[13] |
Rho guanine nucleotide exchange factor 7 (ARHGEF7)
|
OT9BPJCL
|
ARHG7_HUMAN
|
Affects Expression
|
[13] |
ARF GTPase-activating protein GIT2 (GIT2)
|
OTQ2EQJ1
|
GIT2_HUMAN
|
Affects Expression
|
[13] |
Transcription factor Dp-1 (TFDP1)
|
OT6RZ7VT
|
TFDP1_HUMAN
|
Affects Expression
|
[13] |
Transcription factor E2F2 (E2F2)
|
OTO75RM7
|
E2F2_HUMAN
|
Affects Expression
|
[13] |
Translation initiation factor eIF2B subunit alpha (EIF2B1)
|
OT4NCVY1
|
EI2BA_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic initiation factor 4A-II (EIF4A2)
|
OT08H03R
|
IF4A2_HUMAN
|
Affects Expression
|
[13] |
Endonuclease G, mitochondrial (ENDOG)
|
OT5IM7B3
|
NUCG_HUMAN
|
Affects Expression
|
[13] |
Guanine nucleotide-binding protein subunit alpha-13 (GNA13)
|
OTVDL515
|
GNA13_HUMAN
|
Affects Expression
|
[13] |
Sodium channel protein type 5 subunit alpha (SCN5A)
|
OTGYZWR6
|
SCN5A_HUMAN
|
Decreases Activity
|
[64] |
Caspase-8 (CASP8)
|
OTA8TVI8
|
CASP8_HUMAN
|
Increases Activity
|
[49] |
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1)
|
OT9EROL6
|
HERP1_HUMAN
|
Affects Expression
|
[13] |
Advanced glycosylation end product-specific receptor (AGER)
|
OTPY0IH7
|
RAGE_HUMAN
|
Increases Expression
|
[47] |
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PPP2R5A)
|
OTZBCRGI
|
2A5A_HUMAN
|
Affects Expression
|
[13] |
Pregnancy-specific beta-1-glycoprotein 5 (PSG5)
|
OTHTU98X
|
PSG5_HUMAN
|
Increases Expression
|
[41] |
Transcription factor E2F5 (E2F5)
|
OT1XWING
|
E2F5_HUMAN
|
Affects Expression
|
[13] |
Nuclear receptor subfamily 6 group A member 1 (NR6A1)
|
OTFZOOQ9
|
NR6A1_HUMAN
|
Affects Expression
|
[13] |
Ribosomal protein S6 kinase alpha-1 (RPS6KA1)
|
OTDOTWU4
|
KS6A1_HUMAN
|
Affects Expression
|
[13] |
Protein phosphatase 1 regulatory subunit 7 (PPP1R7)
|
OTY5IE69
|
PP1R7_HUMAN
|
Affects Expression
|
[13] |
Nuclear receptor subfamily 0 group B member 2 (NR0B2)
|
OT7UVICX
|
NR0B2_HUMAN
|
Affects Expression
|
[13] |
ETS-related transcription factor Elf-2 (ELF2)
|
OTEI347F
|
ELF2_HUMAN
|
Affects Expression
|
[13] |
Nuclear factor erythroid 2-related factor 2 (NFE2L2)
|
OT0HENJ5
|
NF2L2_HUMAN
|
Increases Stability
|
[13] |
Mitogen-activated protein kinase 14 (MAPK14)
|
OT5TCO3O
|
MK14_HUMAN
|
Affects Expression
|
[13] |
Dihydropyrimidinase-related protein 2 (DPYSL2)
|
OTWNQ74H
|
DPYL2_HUMAN
|
Affects Expression
|
[13] |
Bcl-2 homologous antagonist/killer (BAK1)
|
OTDP6ILW
|
BAK_HUMAN
|
Increases Activity
|
[60] |
Occludin (OCLN)
|
OTSUTVWL
|
OCLN_HUMAN
|
Decreases Expression
|
[42] |
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6)
|
OTM6QYNQ
|
CPSF6_HUMAN
|
Affects Expression
|
[13] |
Hypoxia-inducible factor 1-alpha (HIF1A)
|
OTADSC03
|
HIF1A_HUMAN
|
Decreases Expression
|
[65] |
Programmed cell death protein 4 (PDCD4)
|
OTZ6NXUX
|
PDCD4_HUMAN
|
Decreases Expression
|
[57] |
UMP-CMP kinase 2, mitochondrial (CMPK2)
|
OTOG90R0
|
CMPK2_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 21 (DNAJC21)
|
OT8C14QA
|
DJC21_HUMAN
|
Affects Expression
|
[13] |
Transcription initiation factor TFIID subunit 3 (TAF3)
|
OTVMULE9
|
TAF3_HUMAN
|
Affects Expression
|
[13] |
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (NAPEPLD)
|
OTJI1XF3
|
NAPEP_HUMAN
|
Affects Expression
|
[13] |
General transcription factor IIH subunit 5 (GTF2H5)
|
OTRL219S
|
TF2H5_HUMAN
|
Affects Expression
|
[13] |
Mediator of RNA polymerase II transcription subunit 13-like (MED13L)
|
OTSP1W0F
|
MD13L_HUMAN
|
Affects Expression
|
[13] |
PTB-containing, cubilin and LRP1-interacting protein (PID1)
|
OT5YJ7FI
|
PCLI1_HUMAN
|
Increases Expression
|
[39] |
Glycerate kinase (GLYCTK)
|
OTVTBNSM
|
GLCTK_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 10 (DNAJC10)
|
OTD2EG0R
|
DJC10_HUMAN
|
Affects Expression
|
[13] |
Mitochondrial Rho GTPase 2 (RHOT2)
|
OTV8WT2L
|
MIRO2_HUMAN
|
Affects Expression
|
[13] |
Fanconi anemia group M protein (FANCM)
|
OTNJG99Z
|
FANCM_HUMAN
|
Affects Expression
|
[13] |
Angiogenic factor with G patch and FHA domains 1 (AGGF1)
|
OTA7U2T8
|
AGGF1_HUMAN
|
Affects Expression
|
[13] |
Fanconi anemia group B protein (FANCB)
|
OTMZTXB5
|
FANCB_HUMAN
|
Affects Expression
|
[13] |
Choline dehydrogenase, mitochondrial (CHDH)
|
OTO2DPGL
|
CHDH_HUMAN
|
Affects Expression
|
[13] |
Tudor domain-containing protein 7 (TDRD7)
|
OTK639ET
|
TDRD7_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily B member 14 (DNAJB14)
|
OTAC2K95
|
DJB14_HUMAN
|
Affects Expression
|
[13] |
Cyclic AMP-responsive element-binding protein 3-like protein 4 (CREB3L4)
|
OTSGQGT2
|
CR3L4_HUMAN
|
Affects Expression
|
[13] |
Fibroblast growth factor receptor substrate 2 (FRS2)
|
OTDMD800
|
FRS2_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 9 (DNAJC9)
|
OTDBQBNZ
|
DNJC9_HUMAN
|
Affects Expression
|
[13] |
Histone acetyltransferase KAT6B (KAT6B)
|
OTMUDTAH
|
KAT6B_HUMAN
|
Affects Expression
|
[13] |
Proteasome inhibitor PI31 subunit (PSMF1)
|
OTX84WLQ
|
PSMF1_HUMAN
|
Affects Expression
|
[13] |
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3)
|
OTXGJ8N1
|
P55G_HUMAN
|
Affects Expression
|
[13] |
Hamartin (TSC1)
|
OTFF4YZ7
|
TSC1_HUMAN
|
Affects Expression
|
[13] |
General transcription factor IIH subunit 4 (GTF2H4)
|
OTPD1DIU
|
TF2H4_HUMAN
|
Affects Expression
|
[13] |
TRAF family member-associated NF-kappa-B activator (TANK)
|
OTZSGFIK
|
TANK_HUMAN
|
Affects Expression
|
[13] |
Caspase-10 (CASP10)
|
OTE6J88E
|
CASPA_HUMAN
|
Affects Expression
|
[13] |
DNA repair protein RAD50 (RAD50)
|
OTYMU9G1
|
RAD50_HUMAN
|
Affects Expression
|
[13] |
Rho guanine nucleotide exchange factor 2 (ARHGEF2)
|
OTBQTFRT
|
ARHG2_HUMAN
|
Affects Expression
|
[13] |
Major histocompatibility complex class I-related gene protein (MR1)
|
OTZU3XX7
|
HMR1_HUMAN
|
Affects Expression
|
[45] |
Protein phosphatase 1 regulatory subunit 14B (PPP1R14B)
|
OT9PTWAX
|
PP14B_HUMAN
|
Affects Expression
|
[13] |
Hepatitis A virus cellular receptor 1 (HAVCR1)
|
OT184CRZ
|
HAVR1_HUMAN
|
Increases Expression
|
[50] |
DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3)
|
OT61924T
|
DNJA3_HUMAN
|
Affects Expression
|
[13] |
Thialysine N-epsilon-acetyltransferase (SAT2)
|
OT28QL7H
|
SAT2_HUMAN
|
Affects Expression
|
[13] |
Mediator of RNA polymerase II transcription subunit 30 (MED30)
|
OTM3INJN
|
MED30_HUMAN
|
Affects Expression
|
[13] |
NACHT, LRR and PYD domains-containing protein 3 (NLRP3)
|
OTZM6MHU
|
NLRP3_HUMAN
|
Increases Expression
|
[47] |
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (MAGI1)
|
OTMV4ASV
|
MAGI1_HUMAN
|
Affects Expression
|
[13] |
Formin-binding protein 1 (FNBP1)
|
OTSJ5KKA
|
FNBP1_HUMAN
|
Affects Expression
|
[13] |
Paired amphipathic helix protein Sin3a (SIN3A)
|
OTM8OZWV
|
SIN3A_HUMAN
|
Affects Expression
|
[13] |
Proheparin-binding EGF-like growth factor (HBEGF)
|
OTLU00JS
|
HBEGF_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 3 subunit C (EIF3C)
|
OTR8RF9X
|
EIF3C_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 7 (DNAJC7)
|
OTQ5AL3F
|
DNJC7_HUMAN
|
Affects Expression
|
[13] |
BRCA1-associated RING domain protein 1 (BARD1)
|
OTTC0Z9Y
|
BARD1_HUMAN
|
Affects Expression
|
[13] |
Cell division control protein 6 homolog (CDC6)
|
OTX93FE7
|
CDC6_HUMAN
|
Affects Expression
|
[13] |
Endothelial PAS domain-containing protein 1 (EPAS1)
|
OTRE3O8U
|
EPAS1_HUMAN
|
Decreases Expression
|
[65] |
Growth/differentiation factor 15 (GDF15)
|
OTWQN50N
|
GDF15_HUMAN
|
Increases Expression
|
[66] |
Eukaryotic translation initiation factor 2-alpha kinase 1 (EIF2AK1)
|
OTN0NXX2
|
E2AK1_HUMAN
|
Affects Expression
|
[13] |
Mediator of RNA polymerase II transcription subunit 10 (MED10)
|
OTCQ3ZRR
|
MED10_HUMAN
|
Affects Expression
|
[13] |
Fanconi anemia group J protein (BRIP1)
|
OT38QBD4
|
FANCJ_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 2A (EIF2A)
|
OTWXELQP
|
EIF2A_HUMAN
|
Affects Expression
|
[13] |
Angiotensin-converting enzyme 2 (ACE2)
|
OTTRZGU7
|
ACE2_HUMAN
|
Decreases Expression
|
[40] |
Sulfiredoxin-1 (SRXN1)
|
OTYDBO4L
|
SRXN1_HUMAN
|
Increases Expression
|
[13] |
Group XIIA secretory phospholipase A2 (PLA2G12A)
|
OTHHCQ17
|
PG12A_HUMAN
|
Affects Expression
|
[13] |
Epsin-3 (EPN3)
|
OTNNYDT6
|
EPN3_HUMAN
|
Affects Expression
|
[13] |
DNA replication factor Cdt1 (CDT1)
|
OTVY53VG
|
CDT1_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 5 (DNAJC5)
|
OTCZDXAL
|
DNJC5_HUMAN
|
Affects Expression
|
[13] |
dCTP pyrophosphatase 1 (DCTPP1)
|
OTP1GZYF
|
DCTP1_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 18 (DNAJC18)
|
OTCQNEO7
|
DJC18_HUMAN
|
Affects Expression
|
[13] |
Protein argonaute-3 (AGO3)
|
OTNQGROH
|
AGO3_HUMAN
|
Affects Expression
|
[13] |
MAP kinase-interacting serine/threonine-protein kinase 2 (MKNK2)
|
OTNA9G8V
|
MKNK2_HUMAN
|
Affects Expression
|
[13] |
Transcription initiation factor TFIID subunit 9B (TAF9B)
|
OTORBI4I
|
TAF9B_HUMAN
|
Affects Expression
|
[13] |
Calpain-10 (CAPN10)
|
OTS9LJW4
|
CAN10_HUMAN
|
Affects Expression
|
[13] |
Protein argonaute-4 (AGO4)
|
OTKXQD70
|
AGO4_HUMAN
|
Affects Expression
|
[13] |
Frizzled-3 (FZD3)
|
OTIWDN78
|
FZD3_HUMAN
|
Affects Expression
|
[13] |
Fanconi anemia group F protein (FANCF)
|
OT3WA9N1
|
FANCF_HUMAN
|
Affects Expression
|
[13] |
Transcription factor 7-like 2 (TCF7L2)
|
OTVWPZ8B
|
TF7L2_HUMAN
|
Affects Expression
|
[13] |
Ectonucleoside triphosphate diphosphohydrolase 7 (ENTPD7)
|
OT3QER33
|
ENTP7_HUMAN
|
Affects Expression
|
[13] |
DNA polymerase epsilon subunit 4 (POLE4)
|
OTCMWUT6
|
DPOE4_HUMAN
|
Affects Expression
|
[13] |
Rho guanine nucleotide exchange factor 3 (ARHGEF3)
|
OTHGNC0A
|
ARHG3_HUMAN
|
Affects Expression
|
[13] |
CTP synthase 2 (CTPS2)
|
OT2X9YO1
|
PYRG2_HUMAN
|
Affects Expression
|
[13] |
DNA polymerase epsilon subunit 3 (POLE3)
|
OTOELRF6
|
DPOE3_HUMAN
|
Affects Expression
|
[13] |
Mediator of RNA polymerase II transcription subunit 17 (MED17)
|
OTEZR5GC
|
MED17_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 11 (DNAJC11)
|
OTYLMZWW
|
DJC11_HUMAN
|
Affects Expression
|
[13] |
E3 ubiquitin-protein ligase FANCL (FANCL)
|
OTJC7QPQ
|
FANCL_HUMAN
|
Affects Expression
|
[13] |
Very long chain fatty acid elongase 2 (ELOVL2)
|
OTDAF6U3
|
ELOV2_HUMAN
|
Affects Expression
|
[13] |
Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3)
|
OT0DZGY4
|
E2AK3_HUMAN
|
Increases Activity
|
[13] |
eIF-2-alpha kinase GCN2 (EIF2AK4)
|
OTLE1JY8
|
E2AK4_HUMAN
|
Affects Expression
|
[13] |
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)
|
OTHCDQ22
|
PRGC1_HUMAN
|
Affects Expression
|
[13] |
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L)
|
OT3HG324
|
ASH2L_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily B member 9 (DNAJB9)
|
OT38EQT6
|
DNJB9_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily B member 4 (DNAJB4)
|
OTUD01BK
|
DNJB4_HUMAN
|
Affects Expression
|
[13] |
Mediator of RNA polymerase II transcription subunit 13 (MED13)
|
OTP5LEJE
|
MED13_HUMAN
|
Affects Expression
|
[13] |
Protein TASOR (TASOR)
|
OTEAMOON
|
TASOR_HUMAN
|
Affects Expression
|
[13] |
Apoptotic chromatin condensation inducer in the nucleus (ACIN1)
|
OTK81F92
|
ACINU_HUMAN
|
Affects Expression
|
[13] |
Protein argonaute-2 (AGO2)
|
OT4JY32Q
|
AGO2_HUMAN
|
Affects Expression
|
[13] |
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (ASAP1)
|
OT4DLRYY
|
ASAP1_HUMAN
|
Affects Expression
|
[13] |
Frizzled-4 (FZD4)
|
OTGLZIE0
|
FZD4_HUMAN
|
Affects Expression
|
[13] |
Rho GTPase-activating protein 26 (ARHGAP26)
|
OTNGQU7A
|
RHG26_HUMAN
|
Affects Expression
|
[13] |
GRB2-associated-binding protein 2 (GAB2)
|
OTBFN705
|
GAB2_HUMAN
|
Affects Expression
|
[13] |
Ectonucleoside triphosphate diphosphohydrolase 4 (ENTPD4)
|
OTJ2O8BW
|
ENTP4_HUMAN
|
Affects Expression
|
[13] |
DNA polymerase eta (POLH)
|
OTN07WXU
|
POLH_HUMAN
|
Affects Expression
|
[13] |
Choline/ethanolamine kinase (CHKB)
|
OTNX5LPF
|
CHKB_HUMAN
|
Affects Expression
|
[13] |
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform (PPP2R2C)
|
OTXK0SDM
|
2ABG_HUMAN
|
Affects Expression
|
[13] |
Endophilin-B1 (SH3GLB1)
|
OTAZ5OP8
|
SHLB1_HUMAN
|
Affects Expression
|
[13] |
Mediator of RNA polymerase II transcription subunit 31 (MED31)
|
OTFVKXJE
|
MED31_HUMAN
|
Affects Expression
|
[13] |
DnaJ homolog subfamily C member 15 (DNAJC15)
|
OTNDUKAA
|
DJC15_HUMAN
|
Affects Expression
|
[13] |
Phosphoserine aminotransferase (PSAT1)
|
OTVV1YV9
|
SERC_HUMAN
|
Affects Expression
|
[13] |
NF-kappa-B essential modulator (IKBKG)
|
OTNWJWSD
|
NEMO_HUMAN
|
Affects Expression
|
[13] |
Nuclear receptor coactivator 3 (NCOA3)
|
OTBX300Z
|
NCOA3_HUMAN
|
Affects Expression
|
[13] |
Interleukin-10 (IL10)
|
OTIRFRXC
|
IL10_HUMAN
|
Increases Response To Substance
|
[67] |
Interleukin-4 (IL4)
|
OTOXBWAU
|
IL4_HUMAN
|
Increases Response To Substance
|
[67] |
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