Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGCF51)

Drug Name
Wogonin Drug Info
Synonyms
Wogonin; 632-85-9; 5,7-Dihydroxy-8-methoxyflavone; Vogonin; Norwogonin 8-methyl ether; UNII-POK93PO28W; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-methoxy-2-phenyl-; BRN 0287152; POK93PO28W; 5,7-dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one; CHEMBL16171; FLAVONE, 5,7-DIHYDROXY-8-METHOXY-; CHEBI:10043; XLTFNNCXVBYBSX-UHFFFAOYSA-N; 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one; 5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one; ST077088; Q-100730; 5,7-dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5281703
ChEBI ID
CHEBI:10043
CAS Number
CAS 632-85-9
TTD Drug ID
DMGCF51

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Xanthine dehydrogenase/oxidase (XDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Allopurinol DMLPAOB Gout FA25 Approved [8]
Febuxostat DMDEXQ0 Hyperuricaemia 5C55.Y Approved [9]
Fosdenopterin DMR0TYK Molybdenum cofactor deficiency 5B5K.A Approved [10]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [11]
Oxypurinol DMURH4X Heart failure BD10-BD13 Phase 2/3 [12]
BAICALEIN DM4C7E6 Influenza virus infection 1E30-1E32 Phase 2 [2]
Topiroxostat DMA04DE Gout FA25 Phase 2 [13]
TMX-049 DME8PFQ Diabetic nephropathy GB61.Z Phase 2 [14]
LC-350189 DMHT3CB Gout FA25 Phase 1 [15]
Azaindole derivative 5 DMD2BL3 N. A. N. A. Patented [16]
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Drug(s) Targeting Prostaglandin G/H synthase 2 (COX-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [17]
Naproxen DMZ5RGV Bursitis Approved [18]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [19]
Indomethacin DMSC4A7 Bursitis Approved [20]
Celecoxib DM6LOQU Dysmenorrhea GA34.3 Approved [21]
Nabumetone DMAT2XH Osteoarthritis FA00-FA05 Approved [22]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [23]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [24]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [25]
Aminosalicylic Acid DMENSL5 Crohn disease DD70 Approved [20]
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Drug(s) Affected By Arylamine N-acetyltransferase 1 (NAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Testosterone DM7HUNW Hot flushes GA30 Approved [29]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Folic Acid DMEMBJC Colorectal carcinoma Approved [26]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [32]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [33]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [34]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [35]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [36]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [38]
Ethacrynic acid DM60QMR Edema MG29 Approved [39]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [40]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [41]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [42]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [43]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [44]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [45]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [46]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [48]
Verapamil DMA7PEW Angina pectoris BA40 Approved [49]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [50]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [51]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [52]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [55]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [56]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [57]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [58]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [60]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [61]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [62]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [43]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [62]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [48]
Verapamil DMA7PEW Angina pectoris BA40 Approved [49]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [63]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [64]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [65]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Meloxicam DM2AR7L Arthritis FA20 Approved [67]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [68]
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Drug(s) Affected By Dihydropyrimidine dehydrogenase (DPYD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [69]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [70]
Tegafur DM31ZQM Solid tumour/cancer 2A00-2F9Z Approved [71]
Flucytosine DM13VTW Cryptococcal meningitis Approved [47]
Selenium DM25CGV N. A. N. A. Approved [72]
Quercetin DM3NC4M Obesity 5B81 Approved [73]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [74]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [75]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
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Drug(s) Affected By Insulin (INS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Epinephrine DM3KJBC Acute asthma CA23 Approved [78]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Fructose DM43AN2 Vomiting MD90 Approved [80]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [82]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [83]
Propranolol DM79NTF Angina pectoris BA40 Approved [84]
Testosterone DM7HUNW Hot flushes GA30 Approved [85]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [87]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [88]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [56]
Paclitaxel DMLB81S Breast carcinoma Approved [89]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [90]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [91]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [92]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [94]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [48]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [96]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [97]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [100]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [101]
Methotrexate DM2TEOL Anterior urethra cancer Approved [94]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [102]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [103]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [104]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [96]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [105]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [98]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [106]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [108]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [106]
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Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [109]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [110]
Selenium DM25CGV N. A. N. A. Approved [111]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [112]
Methotrexate DM2TEOL Anterior urethra cancer Approved [113]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [114]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [117]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
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Drug(s) Affected By Glial fibrillary acidic protein (GFAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillin V DMKVOYF Acute otitis media AB00 Approved [47]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [47]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [120]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [121]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Haloperidol DM96SE0 Delirium Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [124]
Ethanol DMDRQZU Chronic pain MG30 Approved [125]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [127]
Selenium DM25CGV N. A. N. A. Approved [72]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [128]
Etretinate DM2CZFA Keratosis ED56 Approved [129]
Methotrexate DM2TEOL Anterior urethra cancer Approved [130]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [131]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [132]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [134]
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Drug(s) Affected By Beta-galactosidase (GLB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [136]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [113]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [139]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [141]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [124]
Bendamustine hydrochloride DMFH15Z leukaemia 2A60-2B33 Approved [142]
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Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [143]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [144]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [145]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [146]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [147]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [148]
Methotrexate DM2TEOL Anterior urethra cancer Approved [149]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [150]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [151]
Quercetin DM3NC4M Obesity 5B81 Approved [73]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [152]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [153]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [52]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [154]
Gefitinib DM15F0X Colon adenocarcinoma Approved [155]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [65]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Selenium DM25CGV N. A. N. A. Approved [72]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [157]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [158]
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Drug(s) Affected By Cyclin-dependent kinase 2 (CDK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [144]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [159]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [160]
Selenium DM25CGV N. A. N. A. Approved [111]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [68]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [161]
Methotrexate DM2TEOL Anterior urethra cancer Approved [162]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [114]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [164]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [165]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [51]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [166]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [167]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [168]
Gefitinib DM15F0X Colon adenocarcinoma Approved [169]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [171]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [172]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [164]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [173]
Paclitaxel DMLB81S Breast carcinoma Approved [174]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [175]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [176]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [51]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [166]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [177]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [178]
Quercetin DM3NC4M Obesity 5B81 Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [180]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [182]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [183]
Testosterone DM7HUNW Hot flushes GA30 Approved [184]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [185]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [186]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [188]
Gefitinib DM15F0X Colon adenocarcinoma Approved [189]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [65]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [146]
Etretinate DM2CZFA Keratosis ED56 Approved [190]
Prednisone DM2HG4X Acute asthma CA23 Approved [191]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [68]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [192]
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Drug(s) Affected By Signal transducer and activator of transcription 3 (STAT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [176]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [193]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [194]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [195]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [196]
Methotrexate DM2TEOL Anterior urethra cancer Approved [197]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [198]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [199]
Quercetin DM3NC4M Obesity 5B81 Approved [200]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [201]
Prednisone DM2HG4X Acute asthma CA23 Approved [191]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [202]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [203]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [87]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [204]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [205]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
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Drug(s) Affected By Proliferation marker protein Ki-67 (MKI67)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [207]
Methotrexate DM2TEOL Anterior urethra cancer Approved [149]
Quercetin DM3NC4M Obesity 5B81 Approved [208]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [117]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [209]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [210]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [212]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [213]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [214]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [215]
Gefitinib DM15F0X Colon adenocarcinoma Approved [155]
Prednisone DM2HG4X Acute asthma CA23 Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [216]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [217]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [218]
Quercetin DM3NC4M Obesity 5B81 Approved [219]
Fluoxetine DM3PD2C Bipolar depression Approved [220]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [221]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [222]
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Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [223]
Gefitinib DM15F0X Colon adenocarcinoma Approved [224]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [225]
Selenium DM25CGV N. A. N. A. Approved [72]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [226]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [227]
Quercetin DM3NC4M Obesity 5B81 Approved [202]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [229]
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Drug(s) Affected By Cyclin-dependent kinase 7 (CDK7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [230]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [211]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [231]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [124]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [232]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [233]
Paclitaxel DMLB81S Breast carcinoma Approved [234]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [235]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [236]
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Drug(s) Affected By Cyclin-dependent kinase 9 (CDK9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [73]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [237]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [124]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [238]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [239]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [240]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [241]
Urethane DM7NSI0 N. A. N. A. Phase 4 [242]
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Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [176]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [52]
Selenium DM25CGV N. A. N. A. Approved [72]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [243]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [244]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [245]
Quercetin DM3NC4M Obesity 5B81 Approved [73]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [246]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [247]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [248]
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Drug(s) Affected By Solute carrier family 22 member 6 (SLC22A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [249]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [250]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [250]
Quercetin DM3NC4M Obesity 5B81 Approved [251]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [250]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [250]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [252]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [250]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [253]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Organic anion transporter 3 (SLC22A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [254]
Methotrexate DM2TEOL Anterior urethra cancer Approved [249]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [255]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [256]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [257]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [257]
Cefdinir DMJ7A0H Bacterial infection 1A00-1C4Z Approved [258]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [258]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [259]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [260]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin G/H synthase 2 (COX-2) TTVKILB PGH2_HUMAN Inhibitor [1]
Xanthine dehydrogenase/oxidase (XDH) TT7RJY8 XDH_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [3]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [3]
Arylamine N-acetyltransferase 1 (NAT1) OTCCNQ3H ARY1_HUMAN Gene/Protein Processing [4]
Beta-galactosidase (GLB1) OTB0TKAG BGAL_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [3]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [6]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [7]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Gene/Protein Processing [7]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Gene/Protein Processing [6]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Gene/Protein Processing [6]

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