General Information of Drug (ID: DMI347A)

Drug Name
Lamivudine Drug Info
Synonyms
lamivudine; 134678-17-4; Epivir; Zeffix; Heptovir; Epivir-HBV; Hepitec; Heptodin; BCH-189; 3TC; Heptivir; CIS-LAMIVUDINE; (-)-2'-Deoxy-3'-thiacytidine; 4-amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one; GR-109714X; 3'-Thia-2',3'-dideoxycytidine; (-)-BCH-189; Lamivudine [USAN:BAN:INN]; GR109714X; beta-L-3'-Thia-2',3'-dideoxycytidine; beta-L-2',3'-Dideoxy-3'-thiacytidine; (-)NGPB-21; 136891-12-8; 2',3'-Dideoxy-3'-thiacytidine; (-)-BCH 189; UNII-2T8Q726O95; HSDB 7155; GR 109714X; DTHC; LMV; Lamivir; Zefix; BCH 189; BCH189; BCH-790; DRG-0126; Epivir (TN); Epivir(TM); GG-714; HHA & 3TC; HHA & Lamivudine; Heptovir (TN); Lamivudine & GNA; Zeffix (TN); Epivir-HBV (TN); Lamivudine [USAN:INN:BAN]; Lamivudine (JAN/USP/INN); Lamivudine, (2S-cis)-Isomer; Beta-L-2',3'-Dideoxy-3'-thiacytidine; Beta-L-3'-Thia-2',3'-dideoxycytidine; Beta-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To; (+/-)-(Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; (+/-)-3TC; (+/-)-BCH-189; (+/-)-SddC; (-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine; (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine; (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; (-)-NGPB-21; (-)-SddC; (-)-beta-L-2',3'-Dideoxy-3'-thiacytidine; (2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one; 2',3' Dideoxy 3' thiacytidine; 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-)-(Cis); 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)-(2R,5S); 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)-(2R,5S) & Galanthus Nivalis Agglutinin (GNA); 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)-(2R,5S) & Hippeastrum hybrid agglutinin(HHA); 3TC & GNA; 3TC & SST; 3TC (AIDS INITIATIVE) (AIDS INITIATIVE); 3TC and NV-01; 3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine; 4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone; 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one; 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one; Efavirenz/lamivudine/tenofovir fumarate
Indication
Disease Entry ICD 11 Status REF
Chronic HBV infection 1E51.0Z Approved [1]
Chronic hepatitis B virus infection Approved [2]
Human immunodeficiency virus infection 1C62 Approved [1]
Human immunodeficiency virus-1 infection 1C62 Approved [3]
Diarrhea ME05.1 Investigative [2]
Therapeutic Class
Anti-HIV Agents
Cross-matching ID
PubChem CID
60825
ChEBI ID
CHEBI:63577
CAS Number
CAS 134678-17-4
TTD Drug ID
DMI347A
VARIDT Drug ID
DR00116
INTEDE Drug ID
DR0912
ACDINA Drug ID
D00347

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [14]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [15]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [16]
Tenofovir DM1IS6U Chronic hepatitis B virus infection Approved [14]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [17]
Delavirdine DM3NF5G Human immunodeficiency virus infection 1C62 Approved [4]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [4]
Rilpivirine DMJ0QOW Human immunodeficiency virus infection 1C62 Approved [18]
Etravirine DMGV8QU Human immunodeficiency virus-1 infection 1C62 Approved [19]
MK-1439 DM215WE Human immunodeficiency virus infection 1C62 Approved [20]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [24]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [25]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [26]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [27]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [26]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [28]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [29]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [32]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [33]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [34]
Propranolol DM79NTF Angina pectoris BA40 Approved [35]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [36]
Metformin DM89QE1 Colorectal carcinoma Approved [37]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [35]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [38]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [39]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [40]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [41]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [42]
Verapamil DMA7PEW Angina pectoris BA40 Approved [43]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [44]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [45]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [46]
Propranolol DM79NTF Angina pectoris BA40 Approved [35]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [47]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [48]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [48]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [38]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [38]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Trospium chloride DM32XZT Discovery agent N.A. Approved [50]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [51]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [52]
Indomethacin DMSC4A7 Bursitis Approved [49]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [51]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [47]
Trospium chloride DM32XZT Discovery agent N.A. Approved [50]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [53]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [54]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [55]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [56]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [49]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [57]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [58]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [12]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [63]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [64]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [65]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [66]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [68]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [69]
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
Quercetin DM3NC4M Obesity 5B81 Approved [71]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [72]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [13]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [73]
Testosterone DM7HUNW Hot flushes GA30 Approved [74]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [75]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [76]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [77]
Verapamil DMA7PEW Angina pectoris BA40 Approved [78]
Selenium DM25CGV N. A. N. A. Approved [79]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [78]
Quercetin DM3NC4M Obesity 5B81 Approved [80]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [82]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [84]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [85]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [76]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [87]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [88]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [89]
Prednisone DM2HG4X Acute asthma CA23 Approved [90]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [91]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [92]
Methotrexate DM2TEOL Anterior urethra cancer Approved [93]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [94]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [95]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [96]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [97]
Methotrexate DM2TEOL Anterior urethra cancer Approved [93]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [98]
Quercetin DM3NC4M Obesity 5B81 Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [101]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [102]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [104]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [105]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [106]
Quercetin DM3NC4M Obesity 5B81 Approved [107]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [109]
Testosterone DM7HUNW Hot flushes GA30 Approved [110]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [111]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [112]
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Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [113]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [76]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [114]
Diazepam DM08E9O Alcohol withdrawal Approved [115]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [116]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [117]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [122]
Etretinate DM2CZFA Keratosis ED56 Approved [123]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [124]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [127]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [130]
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Drug(s) Affected By Endothelin-1 (EDN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [132]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [135]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [82]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [12]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [136]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [137]
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Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [138]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [139]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [142]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [143]
Methotrexate DM2TEOL Anterior urethra cancer Approved [144]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [145]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [146]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
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Drug(s) Affected By Nitric oxide synthase 3 (NOS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [85]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [148]
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [149]
Quercetin DM3NC4M Obesity 5B81 Approved [150]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
Fructose DM43AN2 Vomiting MD90 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [153]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [154]
Selenium DM25CGV N. A. N. A. Approved [155]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [71]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [158]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [132]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [160]
Fluoxetine DM3PD2C Bipolar depression Approved [161]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [162]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [163]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
Aripiprazole DM3NUMH Bipolar I disorder Approved [165]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [163]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [167]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [168]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [169]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [170]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [171]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [172]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [173]
Methotrexate DM2TEOL Anterior urethra cancer Approved [144]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [13]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [175]
Gefitinib DM15F0X Colon adenocarcinoma Approved [176]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [177]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Etretinate DM2CZFA Keratosis ED56 Approved [178]
Prednisone DM2HG4X Acute asthma CA23 Approved [179]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [180]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [181]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [55]
Panobinostat DM58WKG Chronic graft versus host disease Approved [182]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [183]
Pirfenidone DM6VZFQ Idiopathic pulmonary fibrosis CB03.4 Approved [184]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [74]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [186]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [74]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Epinephrine DM3KJBC Acute asthma CA23 Approved [187]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [187]
Norepinephrine DMOUC09 Alopecia ED70 Approved [187]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [188]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [51]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [52]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [189]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [190]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human immunodeficiency virus Reverse transcriptase (HIV RT) TT84ETX POL_HV1B1 Modulator [4]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [5]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [6]
Organic cation transporter 2 (SLC22A2) DT9IDPW S22A2_HUMAN Substrate [7]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Phosphorylcholine transferase A (PCYT1A) DEQYXD4 PCY1A_HUMAN Substrate [8]
Phosphorylethanolamine transferase (PCYT2) DEIX1PO PCY2_HUMAN Substrate [8]
Deoxy-5'-nucleotidase 1 (NT5C) DE4E31Z NT5C_HUMAN Substrate [9]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [10]
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [11]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L) OTJKOMXE BNI3L_HUMAN Gene/Protein Processing [12]
Collagen alpha-1(III) chain (COL3A1) OTT1EMLM CO3A1_HUMAN Gene/Protein Processing [10]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Gene/Protein Processing [13]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [13]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [13]
Endothelin-1 (EDN1) OTZCACEG EDN1_HUMAN Protein Interaction/Cellular Processes [12]
G1/S-specific cyclin-D2 (CCND2) OTDULQF9 CCND2_HUMAN Gene/Protein Processing [13]
G1/S-specific cyclin-E2 (CCNE2) OTBBUKQQ CCNE2_HUMAN Gene/Protein Processing [13]

References

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2 Lamivudine FDA Label
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