Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU8JGH)

Drug Name

Hydralazine Drug Info

Synonyms

Apresolin; Apresoline; Apressin; Apressoline; Aprezolin; HLZ; Hidral; Hidralazin; Hidralazina; Hipoftalin; Hydralazin; Hydralazinum; Hydrallazin; Hydrallazine; Hydrazinophthalazine; Hypophthalin; Idralazina; Hidralazina [Spanish]; Idralazina [DCIT]; Idralazina [Italian]; BA 5968; C 5968; Ciba 5968; Praparat 5968; Apresoline (TN); Apressin (pharmaceutical); C-5068; C-5968; Hidral (TN); Hidralazina [INN-Spanish]; Hydralazine (INN); Hydralazine [INN:BAN]; Hydralazinum [INN-Latin]; Hydrazone 1(2H)-phthalazinone; Phthalazin-1-ylhydrazine; [2H-Phthalazin-(1Z)-Ylidene]-Hydrazine Hydrochloride; (1Z)-1(2H)-Phthalazinone hydrazone; (2H)-Phthalazinone hydrazone; 1(2H)-Phthalazinone hydrazone; 1(2H)-Phthalazinone, hydrazone; 1-Hydrazinophthalazine; 1-Phthalazinylhydrazine; 6-Hydralazine

Indication

Disease Entry	ICD 11	Status	REF
Chronic heart failure	BD1Z	Approved	[1]
Hypertension	BA00-BA04	Approved	[2]
Malignant essential hypertension	BA00	Approved	[1]

Therapeutic Class

Antihypertensive Agents

Cross-matching ID

PubChem CID: 3637
ChEBI ID: CHEBI:5775
CAS Number: CAS 86-54-4
TTD Drug ID: DMU8JGH
VARIDT Drug ID: DR00942
INTEDE Drug ID: DR0813
ACDINA Drug ID: D00311

Molecule-Related Drug Atlas

Molecule Type:

DTT

DME

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Membrane copper amine oxidase (AOC3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Clonidine	DM6RZ9Q	Attention deficit hyperactivity disorder	6A05.Z	Approved	[11]
ASP8232	DMYK1JU	Diabetic macular edema	9B71.02	Phase 2	[12]
BTT-1023	DMIEPJG	Psoriasis vulgaris	EA90	Phase 2	[13]
BI 1467335	DMTE3UV	Diabetic retinopathy	9B71.0	Discontinued in Phase 2	[14]
Vapaliximab	DM73EPK	Inflammation	1A00-CA43.1	Terminated	[15]
Vapill	DM30E56	Diabetic complication	5A2Y	Investigative	[16]
PSX-4206	DMVJDCM	Pulmonary disease	1B10-1F85	Investigative	[16]
RTU-1096	DMWVBD9	Atopic dermatitis	EA80	Investigative	[16]
FP-1102	DMGID4T	Vascular disease	BE2Z	Investigative	[16]
6-hydroxydopa quinone	DM7M58P	Discovery agent	N.A.	Investigative	[17]
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Drug(s) Metabolized By RNA cytidine acetyltransferase (hALP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[18]
Caffeine	DMKBJWP	Allergic rhinitis	CA08.0	Approved	[19]
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[20]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[21]
Sulfadiazine	DMTW3R8	Rheumatic fever	1B40-1B42	Approved	[22]
Tobramycin	DMUI0CH	Bacteremia	1A73	Approved	[23]
Mesalazine	DMOL5IU	Diverticulitis		Approved	[24]
Allopurinol	DMLPAOB	Gout	FA25	Approved	[25]
Netilmicin	DMRD1QK	Bacterial infection	1A00-1C4Z	Approved	[26]
Clonazepam	DMTO13J	Absence epilepsy		Approved	[27]
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Drug(s) Metabolized By N-acetyltransferase 1 (NAT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[28]
Amifampridine	DMK08L3	LambertEaton myasthenic syndrome	8C62	Approved	[29]
Asacolitin	DM3WVPJ	N. A.	N. A.	Investigative	[30]
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Drug(s) Metabolized By N-acetyltransferase 2 (NAT2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[31]
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[32]
Aminosalicylic Acid	DMENSL5	Crohn disease	DD70	Approved	[33]
Amifampridine	DMK08L3	LambertEaton myasthenic syndrome	8C62	Approved	[29]
Asacolitin	DM3WVPJ	N. A.	N. A.	Investigative	[30]
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Drug(s) Affected By Arylamine N-acetyltransferase 2 (NAT2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[34]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[35]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[36]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[37]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[38]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[39]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[40]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[41]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[42]
Sodium Acetate Anhydrous	DMH21E0	Hyponatraemia	5C72	Approved	[43]
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Drug(s) Affected By Estrogen receptor (ESR1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[44]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[45]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[46]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[47]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[48]
Liraglutide	DM3FXPS	Non-insulin dependent diabetes	5A11	Approved	[49]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[50]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[51]
Procaine	DM4LSNE	Anaesthesia	9A78.6	Approved	[47]
Estrone	DM5T6US	Acne vulgaris	ED80	Approved	[52]
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Drug(s) Affected By Glutathione S-transferase P (GSTP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Busulfan	DMXYJ9C	Chronic myelogenous leukaemia	2A20.0	Approved	[53]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[54]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[55]
Chlorambucil	DMRKE63	Chronic lymphocytic leukaemia	2A82.0	Approved	[55]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[56]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[57]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[58]
Selenium	DM25CGV	N. A.	N. A.	Approved	[59]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[60]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[61]
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Drug(s) Affected By Retinoic acid receptor beta (RARB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[62]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[63]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[64]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[65]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[66]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[67]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[68]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[69]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[70]
Vitamin A	DMJ2AH4	Night blindness	9D45	Approved	[62]
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Drug(s) Affected By Methylated-DNA--protein-cysteine methyltransferase (MGMT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DTI-015	DMXZRW0	Brain cancer	2A00	Approved	[71]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[72]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[73]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[41]
Disulfiram	DMCL2OK	Alcohol dependence	6C40.2	Approved	[74]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[75]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[76]
Phenytoin	DMNOKBV	Epilepsy	8A60-8A68	Approved	[77]
Dacarbazine	DMNPZL4	Adenocarcinoma	2D40	Approved	[78]
Topotecan	DMP6G8T	Central nervous system neoplasm		Approved	[79]
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Drug(s) Affected By Adenomatous polyposis coli protein (APC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[58]
Selenium	DM25CGV	N. A.	N. A.	Approved	[59]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[80]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[81]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[82]
Clorgyline	DMCEUJD	Parkinson disease	8A00.0	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[69]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[85]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[86]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[87]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[88]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[89]
Thioridazine	DM35M8J	Schizophrenia	6A20	Approved	[90]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[80]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[91]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[92]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[93]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[94]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[95]
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Drug(s) Affected By Bis(5'-adenosyl)-triphosphatase (FHIT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[97]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[98]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[99]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[100]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[54]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[101]
Methamphetamine	DMPM4SK	Anxiety		Approved	[102]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[103]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[104]
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Drug(s) Affected By Death-associated protein kinase 1 (DAPK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[58]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[97]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[39]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[105]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[106]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[107]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[85]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[108]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[109]
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Drug(s) Affected By Renin (REN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ranitidine	DM0GUSX	Gastric ulcer	DA60	Approved	[110]
Acebutolol	DM0TI4U	Hypertension	BA00-BA04	Approved	[111]
Nitrendipine	DM21C09	Hypertension	BA00-BA04	Approved	[112]
Reboxetine	DM26PRD	Depression	6A70-6A7Z	Approved	[113]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[114]
Ramipril	DM2R68E	Acute heart failure	BD10-BD13	Approved	[115]
Rhucin	DM3ADGP	Erectile dysfunction	HA01.1	Approved	[116]
Naloxone	DM3FXMA	Narcotic depression	6A7Z	Approved	[117]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[118]
Chlorthalidone	DM4DMBT	Edema	MG29	Approved	[119]
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Drug(s) Affected By Tumor necrosis factor (TNF)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Indomethacin	DMSC4A7	Bursitis		Approved	[120]
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[121]
Fructose	DM43AN2	Vomiting	MD90	Approved	[122]
Ketoprofen	DMRKXPT	Bursitis		Approved	[122]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[123]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[124]
Baclofen	DM0QV1J	Multiple sclerosis	8A40	Approved	[125]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[126]
Ganciclovir	DM1MBYQ	Cytomegalovirus infection	1D82	Approved	[127]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[128]
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Drug(s) Affected By Collagen alpha-1(I) chain (COL1A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[122]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[129]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[130]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[62]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[131]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[132]
Ceruletide	DM2WE5K	Caerulein stimulated gastric and pancreatic secretion	5A4Y	Approved	[133]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[134]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[135]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[136]
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Drug(s) Affected By Albumin (ALB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[137]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[122]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[138]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[139]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[140]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[141]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[142]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[143]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[144]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[145]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[146]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[147]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[92]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[148]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[149]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[150]
Floxuridine	DM04LR2	Colorectal cancer	2B91.Z	Approved	[151]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[152]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[153]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[154]
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Drug(s) Affected By Interleukin-6 (IL6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[155]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[156]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[157]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[158]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[159]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[160]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[128]
Imiquimod	DM1TMA3	Alopecia areata	ED70.2	Approved	[161]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[162]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[155]
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Drug(s) Affected By Interleukin-10 (IL10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[163]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[164]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[165]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[166]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[167]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[168]
Bisoprolol	DM3UZ95	Hypertension	BA00-BA04	Approved	[169]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[170]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[171]
Isoniazid	DM5JVS3	Latent tuberculosis infection		Approved	[172]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Membrane copper amine oxidase (AOC3)	TT7HC21	AOC3_HUMAN	Modulator	[3]

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
N-acetyltransferase 1 (NAT1)	DE7OAB3	ARY1_HUMAN	Substrate	[4]
RNA cytidine acetyltransferase (hALP)	DEZV4AP	NAT10_HUMAN	Substrate	[5]
N-acetyltransferase 2 (NAT2)	DER7TA0	ARY2_HUMAN	Substrate	[4]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Adenomatous polyposis coli protein (APC)	OTKV0TIK	APC_HUMAN	Post-Translational Modifications	[6]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Protein Interaction/Cellular Processes	[7]
Arylamine N-acetyltransferase 2 (NAT2)	OTBPDQOY	ARY2_HUMAN	Biotransformations	[8]
Bis(5'-adenosyl)-triphosphatase (FHIT)	OTGWBSLA	FHIT_HUMAN	Gene/Protein Processing	[6]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Gene/Protein Processing	[9]
Collagen alpha-1(I) chain (COL1A1)	OTI31178	CO1A1_HUMAN	Gene/Protein Processing	[10]
Cyclin-dependent kinase inhibitor 2A (CDKN2A)	OTN0ZWAE	CDN2A_HUMAN	Post-Translational Modifications	[6]
Death-associated protein kinase 1 (DAPK1)	OTNCNUCO	DAPK1_HUMAN	Gene/Protein Processing	[6]
Estrogen receptor (ESR1)	OTKLU61J	ESR1_HUMAN	Gene/Protein Processing	[6]
Glutathione S-transferase P (GSTP1)	OTLP0A0Y	GSTP1_HUMAN	Gene/Protein Processing	[6]

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References

1	Hydralazine FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7326).
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
4	N-acetyltransferase 2 genotype-dependent N-acetylation of hydralazine in human hepatocytes. Drug Metab Dispos. 2017 Dec;45(12):1276-1281.
5	Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension. Clin Pharmacol Ther. 1981 May;29(5):588-93.
6	A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes. BMC Cancer. 2005 Apr 29;5:44.
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