Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUXQG7)

Drug Name
Phosphate Drug Info
Synonyms
orthophosphate; Phosphate ion; 14265-44-2; O-Phosphate; UNII-NK08V8K8HR; NK08V8K8HR; Phosphates; Phosphate ions; PO4; a phosphate group; tetraoxophosphate(V); tetraoxophosphate(3-); Phosphoric acid trianion; tetraoxidophosphate(3-); phosphoric acid, ion(3-); AC1L1AN2; DTXSID7039672; CHEBI:18367; CTK0H5978; NBIIXXVUZAFLBC-UHFFFAOYSA-K; BDBM50155537; AKOS015903596; PO4(3-); CREATINE PHOSPHATE; N-PHOSPHOCREATINE; [PO4](3-); I14-18227
Indication
Disease Entry ICD 11 Status REF
Constipation DD91.1 Approved [1]
Cross-matching ID
PubChem CID
1061
ChEBI ID
CHEMBL18367
CAS Number
CAS 14265-44-2
TTD Drug ID
DMUXQG7
VARIDT Drug ID
DR00132
INTEDE Drug ID
DR2121

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Transported By Sodium-dependent phosphate transport protein 1 (SLC17A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [7]
Drug(s) Transported By Sodium-dependent phosphate transport protein 4 (SLC17A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
AMINOHIPPURIC ACID DMUN54G Discovery agent N.A. Investigative [12]
Drug(s) Transported By Probable small intestine urate exporter (SLC17A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [11]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [11]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [11]
Drug(s) Transported By Vesicular glutamate transporter 2 (SLC17A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [21]
Drug(s) Transported By Vesicular glutamate transporter 1 (SLC17A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [21]
Drug(s) Transported By Mitochondrial dicarboxylate carrier (SLC25A10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SULFATE DMW0ZBF Discovery agent N.A. Investigative [2]
Drug(s) Transported By Glycerol-3-phosphate permease (SLC37A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glucose-6-Phosphate DMKY1L4 N. A. N. A. Phase 1 [10]
Drug(s) Metabolized By GDP-D-glucose phosphorylase 1 (GDPGP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
GDP-alpha-D-glucose DMF6MUB N. A. N. A. Investigative [13]
Drug(s) Affected By Sodium-dependent phosphate transporter 2 (SLC20A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [22]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [23]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [24]
Testosterone DM7HUNW Hot flushes GA30 Approved [25]
Leflunomide DMR8ONJ Arthritis FA20 Approved [26]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [27]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [29]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [30]
Arsenic DMTL2Y1 N. A. N. A. Approved [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-dependent phosphate transporter 1 (SLC20A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [23]
Leflunomide DMR8ONJ Arthritis FA20 Approved [26]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [35]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [36]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [37]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphate-regulating neutral endopeptidase PHEX (PHEX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [38]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [39]
Glycerol-2-Phosphate DM0J5KF Discovery agent N.A. Investigative [40]
Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [41]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [42]
Gefitinib DM15F0X Colon adenocarcinoma Approved [43]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [45]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [46]
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [48]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dentin matrix acidic phosphoprotein 1 (DMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [51]
Drug(s) Affected By Growth arrest-specific protein 6 (GAS6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
Folic Acid DMEMBJC Colorectal carcinoma Approved [52]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [53]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [54]
Sodium phenylbutyrate DMXLBCQ Spinal muscular atrophy 8B61 Approved [55]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [56]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [57]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [16]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [58]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [60]
Sorbitol DMAN0DE Constipation DD91.1 Approved [59]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [61]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [29]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [62]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [62]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [63]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Matrix extracellular phosphoglycoprotein (MEPE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [65]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [66]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [67]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Mitochondrial dicarboxylate carrier (SLC25A10) DTJYKDQ DIC_HUMAN Substrate [2]
Phosphate carrier protein (SLC25A3) DTCRIWV MPCP_HUMAN Substrate [3]
Calcium-binding mitochondrial carrier protein SCaMC-3 (SLC25A23) DTLQ0EZ SCMC3_HUMAN Substrate [4]
Sodium-dependent phosphate transporter 2 (SLC20A2) DTFD4VB S20A2_HUMAN Substrate [5]
Sodium-dependent phosphate transporter 1 (SLC20A1) DTMULXV S20A1_HUMAN Substrate [5]
Vesicular glutamate transporter 1 (SLC17A7) DTNK0FR VGLU1_HUMAN Substrate [6]
Vesicular glutamate transporter 2 (SLC17A6) DT5LHCR VGLU2_HUMAN Substrate [7]
Calcium-binding mitochondrial carrier protein SCaMC-2 (SLC25A25) DTN7X5J SCMC2_HUMAN Substrate [8]
Calcium-binding mitochondrial carrier protein SCaMC-1 (SLC25A24) DTVAEDK SCMC1_HUMAN Substrate [9]
Glycerol-3-phosphate permease (SLC37A1) DTH9SQJ G6PT2_HUMAN Substrate [10]
Probable small intestine urate exporter (SLC17A4) DTHE530 S17A4_HUMAN Substrate [11]
Sodium-dependent phosphate transport protein 4 (SLC17A3) DTFOJL7 NPT4_HUMAN Substrate [12]
Sodium-dependent phosphate transport protein 1 (SLC17A1) DT8ARWJ NPT1_HUMAN Substrate [7]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
GDP-D-glucose phosphorylase 1 (GDPGP1) Main DME DE9P5K7 GDPP1_HUMAN Substrate [13]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Protein Interaction/Cellular Processes [14]
Dentin matrix acidic phosphoprotein 1 (DMP1) OTBWBWW7 DMP1_HUMAN Gene/Protein Processing [15]
Growth arrest-specific protein 6 (GAS6) OTPOPUUE GAS6_HUMAN Gene/Protein Processing [16]
MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1) OTGBRJDQ MKNK1_HUMAN Gene/Protein Processing [17]
Matrix extracellular phosphoglycoprotein (MEPE) OTXJRUW0 MEPE_HUMAN Regulation of Drug Effects [18]
Phosphate-regulating neutral endopeptidase PHEX (PHEX) OTG7N3J7 PHEX_HUMAN Gene/Protein Processing [19]
Sodium-dependent phosphate transporter 1 (SLC20A1) OTC3D894 S20A1_HUMAN Gene/Protein Processing [14]
Sodium-dependent phosphate transporter 2 (SLC20A2) OT6E2DAX S20A2_HUMAN Gene/Protein Processing [14]
Solute carrier family 53 member 1 OTG4FVQB S53A1_HUMAN Regulation of Drug Effects [20]

References

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