Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSNVGB)

• Drug Name: Echothiophate Iodide Drug Info
• Synonyms: Echodide; Phospholine; Diethoxyphosphinylthiocholine iodide; ECOTHIOPATE IODIDE; Ecostigmini jodidum; Ecothiopati iodidum; Ecothiophate iodide; Ioduro de ecotiopato; Phospholine iodide; Diethoxyphosphoryl-thiocholine iodide; Echothiophate iodide (USP); Ecothiopati iodidum [INN-Latin]; Iodide, Echothiophate; Iodide, Ecothiopate; Iodide, Ecothiophate; Iodide, Phospholine; Iodure d'ecothiopate; Ioduro de ecotiopato [INN-Spanish]; Phospholine (the pharmaceutical); Phospholine Iodide (TN); Phospholine iodide (TN); Ecothiopate iodide (JP15/INN); Iodure d'ecothiopate [INN-French]; N-(2-(Diethoxyphosphinylthio)ethyl)trimethylammonium iodide; O,O-Diethyl S-2-trimethylammonium ethylphosphonothiolate iodide; S-Ester of (2-mercaptoethyl)trimethylammonium iodide with O,O-diethyl phosphorothioate; S-beta-dimethylaminoethyl-O,O-diethylthionophosphate methiodide; S-(2-Dimethylaminoethyl)-O.O-diethylphosphorothioate methiodide; S-(2-dimethylaminoethyl)-O,O-diethylphosphorothioate methiodide; Ammonium, (2-(O,O-diethylphosphorothio)ethyl)trimethyl-, iodide; Ammonium, (2-mercaptoethyl)trimethyl-, iodide, S-ester with O,O-diethylphosphorothioate; S-(2-(N,N,N-Trimethylammonio)ethyl) O,O-diethylphosphorothiolate iodide; Ethanaminium, 2-((diethoxyphosphinyl)thio)-N,N,N-trimethyl-, iodide; (2-Mercaptoethyl)trimethylammonium iodide S-ester with O,O-diethyl phosphorothioate; (2-mercaptoethyl)trimethylammonium iodidie O,O-diethyl phosphorothioate; 2-((Diethoxyphosphinyl)thio)-N,N,N,-trimethylethanaminium iodide; 2-Diaethoxyphosphinyl-thioaethyl-trimethyl-ammonium-jodid; 2-Diaethoxyphosphinyl-thioaethyl-trimethyl-ammonium-jodid [German]; 2-Diethoxy-phosphinylthioethyl-trimethylammonium iodide; 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethylethanaminium iodide; 2-[(diethoxyphosphoryl)sulfanyl]-N,N,N-trimethylethanaminium iodide; 2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium iodide; 2-{[bis(ethyloxy)phosphoryl]thio}-N,N,N-trimethylethanaminium iodide; 217 MI; 217-mi

Indication

Disease Entry	ICD 11	Status	REF
Chronic glaucoma	9C61.0Z	Approved	[1]

• Therapeutic Class: Parasympathomimetics
• Cross-matching ID:
  PubChem CID: 10547
  ChEBI ID: CHEBI:59849
  CAS Number: CAS 513-10-0
  TTD Drug ID: DMSNVGB
  ACDINA Drug ID: D01027

Molecule-Related Drug Atlas

Drug(s) Targeting Acetylcholinesterase (AChE)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tacrine	DM51FY6	Alzheimer disease	8A20	Approved	[5]
Donepezil	DMIYG7Z	Advanced cancer	2A00-2F9Z	Approved	[6]
Malathion	DMXZ84M	Pediculus capitis infestation	1G00.0	Approved	[7]
Galantamine	DMEO794	Alzheimer disease	8A20	Approved	[8]
Huperzine A	DMMAWLU	Alzheimer disease	8A20	Approved	[9]
Neostigmine	DM6T2J3	Myasthenia gravis	8C6Y	Approved	[10]
YM443	DMNZCI1	Functional dyspepsia	DD90.3	Approved	[11]
Ambenonium	DMOP0BL	Myasthenia gravis	8C6Y	Approved	[12]
Demecarium bromide	DMAYEU1	Open-angle glaucoma	9C61	Approved	[13]
Isoflurophate	DMBSK7X	Glaucoma/ocular hypertension	9C61	Approved	[14]

Drug(s) Affected By Cholinesterase (BCHE)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[15]
Tacrine	DM51FY6	Alzheimer disease	8A20	Approved	[16]
Galantamine	DMEO794	Alzheimer disease	8A20	Approved	[17]
Rivastigmine	DMG629M	Alzheimer disease	8A20	Approved	[18]
Donepezil	DMIYG7Z	Advanced cancer	2A00-2F9Z	Approved	[19]
Succinylcholine	DM2ET1M	Plasma cell myeloma	2A83.1	Approved	[20]
Ethopropazine	DM0N3L7	Parkinson disease	8A00.0	Approved	[16]
Dimenhydrinate	DM264B3	Meniere disease	AB31.0	Approved	[21]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[22]
Chlorpheniramine	DM5URA2	Allergic rhinitis	CA08.0	Approved	[21]

Drug(s) Affected By Albumin (ALB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[23]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[19]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[24]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[25]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[26]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[27]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[28]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[29]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[30]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[31]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Modulator	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Protein Interaction/Cellular Processes	[3]
Cholinesterase (BCHE)	OTOH3WQ9	CHLE_HUMAN	Gene/Protein Processing	[4]

References

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