Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2Y3P4)

Drug Name
Chlorogenic acid Drug Info
Synonyms
CHLOROGENIC ACID; 327-97-9; 3-Caffeoylquinic acid; 3-O-Caffeoylquinic acid; 3-(3,4-Dihydroxycinnamoyl)quinic acid; Chlorogenate; Heriguard; Hlorogenic acid; Caffeoyl quinic acid; NSC-407296; 3-Caffeoylquinate; UNII-318ADP12RI; 5-O-(3,4-Dihydroxycinnamoyl)-L-quinic acid; CCRIS 1400; Chlorogenic acid (8CI); EINECS 206-325-6; NSC 70861; NSC 407296; 3-trans-Caffeoylquinic acid; CHEMBL284616; 318ADP12RI; CHEBI:16112; 1,3,4,5-tetrahydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate); 3-(3,4-Dihydroxycinnamoyl)quinate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1794427
ChEBI ID
CHEMBL284616
CAS Number
CAS 202650-88-2
TTD Drug ID
DM2Y3P4
VARIDT Drug ID
DR00938

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Investigative Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Glucose-6-phosphate translocase (SLC37A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
S 0957 DM9HA8G Discovery agent N.A. Investigative [5]
S 1743 DMA5GOX Discovery agent N.A. Investigative [5]
S-4048 DME5HIR Discovery agent N.A. Investigative [6]
Kodaistatin A DMAJKRX Discovery agent N.A. Investigative [7]
Kodaistatin C DM72WQ3 Discovery agent N.A. Investigative [7]
S 3025 DMZN0RW Discovery agent N.A. Investigative [8]
Mumbaistatin DM6SYMH Discovery agent N.A. Investigative [9]
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Drug(s) Affected By Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [12]
Arsenic DMTL2Y1 N. A. N. A. Approved [13]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [14]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [2]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [2]
GUAIACOL DMN4E7T N. A. N. A. Phase 3 [2]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [2]
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Drug(s) Affected By Cytochrome c oxidase subunit 1 (COX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [16]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [17]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [18]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [19]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [21]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [12]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [22]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [23]
Nicotinamide DMUPE07 Acne vulgaris ED80 Approved [18]
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Drug(s) Affected By Collagen alpha-1(I) chain (COL1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [24]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Diazepam DM08E9O Alcohol withdrawal Approved [26]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [27]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Ceruletide DM2WE5K Caerulein stimulated gastric and pancreatic secretion 5A4Y Approved [30]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [31]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [33]
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Drug(s) Affected By Heat shock protein beta-1 (HSPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [35]
Selenium DM25CGV N. A. N. A. Approved [36]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [40]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [19]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
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Drug(s) Affected By Fibroblast growth factor 1 (FGF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [45]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [46]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [48]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [45]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [49]
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Drug(s) Affected By Extracellular superoxide dismutase (SOD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [53]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [55]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [56]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [57]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [58]
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Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [27]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [60]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [61]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [63]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [66]
Panobinostat DM58WKG Chronic graft versus host disease Approved [67]
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Drug(s) Affected By Keratin, type II cytoskeletal 5 (KRT5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [45]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [45]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [69]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [12]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [45]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [71]
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Drug(s) Affected By CD44 antigen (CD44)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [72]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [73]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Selenium DM25CGV N. A. N. A. Approved [75]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [76]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [77]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [78]
Panobinostat DM58WKG Chronic graft versus host disease Approved [67]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [79]
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Drug(s) Affected By Fibrillin-1 (FBN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [80]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Panobinostat DM58WKG Chronic graft versus host disease Approved [67]
Leflunomide DMR8ONJ Arthritis FA20 Approved [82]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [83]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [84]
Paclitaxel DMLB81S Breast carcinoma Approved [85]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
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Drug(s) Affected By Fibrillin-2 (FBN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [83]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [87]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [88]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [89]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [90]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [91]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [92]
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Drug(s) Affected By UV excision repair protein RAD23 homolog A (RAD23A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [36]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [93]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [10]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [12]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [95]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [96]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [97]
Arsenic DMTL2Y1 N. A. N. A. Approved [98]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [42]
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Drug(s) Affected By Melanocyte-stimulating hormone receptor (MC1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [99]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [18]
Clozapine DMFC71L Schizophrenia 6A20 Approved [100]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [95]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [74]
Urethane DM7NSI0 N. A. N. A. Phase 4 [101]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [2]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [2]
GUAIACOL DMN4E7T N. A. N. A. Phase 3 [2]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [2]
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Drug(s) Affected By Cytoglobin (CYGB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [103]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [49]
Arsenic DMTL2Y1 N. A. N. A. Approved [104]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [105]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [92]
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Drug(s) Affected By Hyaluronan synthase 1 (HAS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [106]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [92]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [2]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [2]
GUAIACOL DMN4E7T N. A. N. A. Phase 3 [2]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [2]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [107]
Puerarin DMJIMXH Alcohol dependence 6C40.2 Phase 2 [2]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [108]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [109]
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Drug(s) Affected By Prothrombin (F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [110]
Methotrexate DM2TEOL Anterior urethra cancer Approved [111]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [113]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [114]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [115]
Phytonadione DM8HDOL Bleeding disorder GA20-GA21 Approved [116]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [10]
Testosterone enanthate DMB6871 N. A. N. A. Approved [117]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [118]
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Drug(s) Affected By Biotin--protein ligase (HLCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [4]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [120]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [119]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [121]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [12]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [96]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [122]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [74]
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Drug(s) Affected By Bile acid receptor (NR1H4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [124]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [126]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [127]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [124]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [125]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [128]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [10]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucose-6-phosphate translocase (SLC37A4) TT1KPBZ G6PT1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5,6-dihydroxyindole-2-carboxylic acid oxidase OTRK49R4 TYRP1_HUMAN Gene/Protein Processing [2]
Bile acid receptor (NR1H4) OTWZLPTB NR1H4_HUMAN Gene/Protein Processing [3]
Biotin--protein ligase (HLCS) OTPDUX30 BPL1_HUMAN Gene/Protein Processing [4]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Gene/Protein Processing [2]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Gene/Protein Processing [2]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Gene/Protein Processing [2]
Cytochrome c oxidase subunit 1 (COX1) OTG3O9BN COX1_HUMAN Gene/Protein Processing [2]
Cytoglobin (CYGB) OTX153DQ CYGB_HUMAN Gene/Protein Processing [2]
Extracellular superoxide dismutase (SOD3) OTIOZQAB SODE_HUMAN Gene/Protein Processing [2]
Fibrillin-1 (FBN1) OTYCJT63 FBN1_HUMAN Gene/Protein Processing [2]

References

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12 Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. J Cell Physiol. 2021 Apr;236(4):2959-2975. doi: 10.1002/jcp.30055. Epub 2020 Sep 22.
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