Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHO29Y)

Drug Name
T83193 Drug Info
Synonyms
vanillin; 4-Hydroxy-3-methoxybenzaldehyde; 121-33-5; Vanillaldehyde; Vanillic aldehyde; Vanilla; p-Vanillin; 2-Methoxy-4-formylphenol; Vanilline; Lioxin; 4-Hydroxy-m-anisaldehyde; 3-Methoxy-4-hydroxybenzaldehyde; Zimco; Benzaldehyde, 4-hydroxy-3-methoxy-; 4-Hydroxy-3-methoxy-benzaldehyde; Vanilin; p-Hydroxy-m-methoxybenzaldehyde; 4-Formyl-2-methoxyphenol; Methylprotocatechuic aldehyde; Vanillin (natural); 4-Hydroxy-5-methoxybenzaldehyde; m-Anisaldehyde, 4-hydroxy-; Protocatechualdehyde, methyl-; Vanillin [USAN]; Vanillin (NF)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1183
ChEBI ID
CHEMBL13883
CAS Number
CAS 121-33-5
TTD Drug ID
DMHO29Y

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Succinate-semialdehyde dehydrogenase (ALDH5A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Chlormerodrin DMSF4PR Diagnostic imaging N.A. Approved [7]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [8]
1-(4-hydroxyphenyl)prop-2-en-1-one DM145QS Discovery agent N.A. Investigative [2]
Drug(s) Targeting GABA transaminase (ABAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Alanine DMZDN4W Dietary shortage 5B5K Approved [9]
Pyridoxal Phosphate DMO2K0J Malnutrition 5B50-5B71 Approved [9]
Pyruvic acid DM7Q41G Malnutrition 5B50-5B71 Approved [9]
Vigabatrin DMYT0OG Alcohol dependence 6C40.2 Approved [10]
Divalproex sodium DM4RK0G Seizure disorder 8A6Z Approved [9]
CPP-115 DMK9NQI Tourette syndrome 8A05.00 Phase 2 [11]
K-828-AB DMJLNZQ Dementia 6D80-6D86 Phase 2 [12]
CPP -15 DMQCHU3 Infantile spasm 8A62.0 Phase 1 [11]
4-hydroxybenzaldehyde DM471P5 Discovery agent N.A. Patented [13]
Acetate Ion DMD08RH Discovery agent N.A. Investigative [14]
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Drug(s) Targeting Monoamine oxidase type B (MAO-B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selegiline Hydrochloride DM3VR1L Parkinson disease 8A00.0 Approved [15]
Phenelzine DMHIDUE Depression 6A70-6A7Z Approved [16]
Tranylcypromine DMGB5RE Major depressive disorder 6A70.3 Approved [17]
Selegiline DM6034S Major depressive disorder 6A70.3 Approved [18]
Safinamide mesylate DM0J2ZT Parkinson disease 8A00.0 Approved [19]
Rasagiline DM3WKQ4 Parkinson disease 8A00.0 Approved [20]
Sulphadoxine DMZI2UF Malaria 1F40-1F45 Approved [21]
Pargyline DMM0HR1 Hypertension BA00-BA04 Approved [22]
Indeloxazine DMWO3N6 Dementia 6D80-6D86 Approved [23]
Budipine DMODHQI Migraine 8A80 Approved [24]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [25]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [26]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [27]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [28]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [29]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [30]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [31]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [32]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [33]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [31]
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Drug(s) Affected By Aldo-keto reductase family 1 member C2 (AKR1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [34]
Diazepam DM08E9O Alcohol withdrawal Approved [35]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [4]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [34]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [38]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [39]
Testosterone DM7HUNW Hot flushes GA30 Approved [40]
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Drug(s) Affected By Insulin-induced gene 1 protein (INSIG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [41]
Fluoxetine DM3PD2C Bipolar depression Approved [42]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [43]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [44]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [45]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [44]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [47]
Testosterone DM7HUNW Hot flushes GA30 Approved [48]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [49]
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Drug(s) Affected By Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [51]
Panobinostat DM58WKG Chronic graft versus host disease Approved [52]
Testosterone DM7HUNW Hot flushes GA30 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [56]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [57]
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Drug(s) Affected By Tripartite motif-containing protein 16 (TRIM16)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [58]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [60]
Testosterone enanthate DMB6871 N. A. N. A. Approved [61]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [56]
Ampicillin DMHWE7P Acute epiglottitis Approved [62]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [63]
Penicillin V DMKVOYF Acute otitis media AB00 Approved [62]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [64]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [65]
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Drug(s) Affected By Glycogen phosphorylase, liver form (PYGL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Testosterone DM7HUNW Hot flushes GA30 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [56]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [49]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [69]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [70]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [71]
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Drug(s) Affected By Transcription factor JunD (JUND)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [29]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [74]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [76]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [78]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [79]
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Drug(s) Affected By CCN family member 2 (CCN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [81]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [43]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [83]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [84]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [85]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [87]
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Drug(s) Affected By Glucose-6-phosphatase catalytic subunit 1 (G6PC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Fluoxetine DM3PD2C Bipolar depression Approved [88]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [43]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [89]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [90]
Leflunomide DMR8ONJ Arthritis FA20 Approved [91]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [54]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [43]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [43]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [92]
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Drug(s) Affected By Dual specificity protein kinase CLK2 (CLK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [93]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [47]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [71]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [94]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [96]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [97]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [98]
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Drug(s) Affected By Frizzled-2 (FZD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Methotrexate DM2TEOL Anterior urethra cancer Approved [100]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Panobinostat DM58WKG Chronic graft versus host disease Approved [52]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [104]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [69]
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Drug(s) Affected By Dual specificity protein phosphatase 6 (DUSP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [107]
Leflunomide DMR8ONJ Arthritis FA20 Approved [108]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
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Drug(s) Affected By Nucleotide sugar transporter SLC35D2 (SLC35D2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [109]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [71]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [111]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [112]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [113]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [114]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [115]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [116]
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Drug(s) Affected By MAP/microtubule affinity-regulating kinase 4 (MARK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [117]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [58]
Leflunomide DMR8ONJ Arthritis FA20 Approved [108]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [119]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [111]
Urethane DM7NSI0 N. A. N. A. Phase 4 [120]
Rigosertib DMOSTXF Myelodysplastic syndrome 2A37 Phase 3 [121]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [122]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
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Drug(s) Affected By Serine/threonine-protein phosphatase 1 regulatory subunit 10 (PPP1R10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Selenium DM25CGV N. A. N. A. Approved [123]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [56]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [124]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [71]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [125]
Arsenic DMTL2Y1 N. A. N. A. Approved [126]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [111]
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Drug(s) Affected By DNA damage-inducible transcript 4 protein (DDIT4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [87]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [41]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [100]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [76]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [129]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [130]
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Drug(s) Affected By DNA (DNMT3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [132]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [133]
Testosterone DM7HUNW Hot flushes GA30 Approved [48]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [48]
Leflunomide DMR8ONJ Arthritis FA20 Approved [108]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ethanol DMDRQZU Chronic pain MG30 Approved [134]
Folic Acid DMEMBJC Colorectal carcinoma Approved [135]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA transaminase (ABAT) TTT2LD9 GABT_HUMAN Inhibitor [2]
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Inhibitor [3]
Succinate-semialdehyde dehydrogenase (ALDH5A1) TTJUWVB SSDH_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Gene/Protein Processing [4]
CCN family member 2 (CCN2) OTC39NSU CCN2_HUMAN Gene/Protein Processing [5]
DNA (DNMT3B) OTZ0JCNP DNM3B_HUMAN Gene/Protein Processing [5]
DNA damage-inducible transcript 4 protein (DDIT4) OTHY8SY4 DDIT4_HUMAN Gene/Protein Processing [5]
Dual specificity protein kinase CLK2 (CLK2) OT1CRSY2 CLK2_HUMAN Gene/Protein Processing [5]
Dual specificity protein phosphatase 6 (DUSP6) OT4H6RKW DUS6_HUMAN Gene/Protein Processing [5]
Frizzled-2 (FZD2) OT952ML1 FZD2_HUMAN Gene/Protein Processing [5]
Glucose-6-phosphatase catalytic subunit 1 (G6PC1) OTJ6FM9F G6PC1_HUMAN Protein Interaction/Cellular Processes [6]
Glycogen phosphorylase, liver form (PYGL) OTS1YFGR PYGL_HUMAN Protein Interaction/Cellular Processes [6]
Insulin-induced gene 1 protein (INSIG1) OTZF5X1D INSI1_HUMAN Gene/Protein Processing [5]

References

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6 Vanillin exerts therapeutic effects against hyperglycemia-altered glucose metabolism and purinergic activities in testicular tissues of diabetic rats. Reprod Toxicol. 2021 Jun;102:24-34. doi: 10.1016/j.reprotox.2021.03.007. Epub 2021 Apr 3.
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