Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIW453)

Drug Name
Pelitinib Drug Info
Synonyms EKB-569; EKI-569; WAY-EKB-569
Indication
Disease Entry ICD 11 Status REF
Lymphoma 2A80-2A86 Phase 2 [1]
Cross-matching ID
PubChem CID
6445562
ChEBI ID
CHEMBL38927
CAS Number
CAS 257933-82-7
TTD Drug ID
DMIW453

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [4]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [5]
Gefitinib DM15F0X Colon adenocarcinoma Approved [6]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [7]
Vandetanib DMRICNP Solid tumour/cancer 2A00-2F9Z Approved [8]
Dacomitinib DMOH8VY Non-small-cell lung cancer 2C25.Y Approved [9]
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [10]
SKI-758 DMQ8E9R Ischemia 8B10-8B11 Approved [11]
Epidermal growth factor DMVONE6 Vulnerary ND56.Z Approved [9]
Merimepodib DM0HS92 Breast cancer 2C60-2C65 Approved [12]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [13]
Gefitinib DM15F0X Colon adenocarcinoma Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [15]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [16]
Etretinate DM2CZFA Keratosis ED56 Approved [17]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [18]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [19]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [20]
Quercetin DM3NC4M Obesity 5B81 Approved [21]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [22]
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Drug(s) Affected By B-cell lymphoma/leukemia 10 (BCL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [24]
Testosterone DM7HUNW Hot flushes GA30 Approved [25]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [25]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [26]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [27]
Menthol DMG2KW7 Back pain ME84.Z Approved [28]
Capsaicin DMGMF6V Back pain ME84.Z Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
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Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-1 (ATF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [33]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [35]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [30]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [36]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [37]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [35]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [38]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [39]
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Drug(s) Affected By B-cell lymphoma 3 protein (BCL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
Selenium DM25CGV N. A. N. A. Approved [41]
Methotrexate DM2TEOL Anterior urethra cancer Approved [42]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Leflunomide DMR8ONJ Arthritis FA20 Approved [44]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [45]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [45]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [46]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [45]
Menthol DMG2KW7 Back pain ME84.Z Approved [28]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [16]
Selenium DM25CGV N. A. N. A. Approved [41]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [51]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [53]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [54]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 1 (NAIP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Menthol DMG2KW7 Back pain ME84.Z Approved [28]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [57]
Bortezomib DMNO38U Leukemia Approved [58]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [60]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [61]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [62]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [63]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [64]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [52]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [66]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [68]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [69]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [70]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [71]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Epidermal growth factor receptor (EGFR) TTGKNB4 EGFR_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
B-cell lymphoma 3 protein (BCL3) OT1M5B95 BCL3_HUMAN Gene/Protein Processing [3]
B-cell lymphoma/leukemia 10 (BCL10) OT47MCLI BCL10_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 1 (NAIP) OTLA925F BIRC1_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [3]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [3]
Cyclic AMP-dependent transcription factor ATF-1 (ATF1) OT251CI0 ATF1_HUMAN Gene/Protein Processing [3]

References

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