Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5VWOB)

Drug Name
Methylscopolamine Drug Info
Synonyms
Methscopolamine; methscopolamine; N-Methylscopolamine; N-methyl scopolamine; UNII-VDR09VTQ8U; VDR09VTQ8U; 13265-10-6; CHEMBL376897; (1r,2r,4s,5s)-7-{[(2s)-3-hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[33102,4]nonane; Metylskopolamin; 56552-70-6; 3-Oxa-9-azoniatricyclo[33102,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, (1a,2b,4b,5a,7b); HSDB 5420; [3H]N-methylscopolamine; [3H]N-methyl scopolamine; [3H]NMS; Methyl scopolamine; 3C0
Indication
Disease Entry ICD 11 Status REF
Peptic ulcer DA61 Approved [1]
Therapeutic Class
Anticholinergic Agents
Cross-matching ID
PubChem CID
71183
ChEBI ID
CHEBI:135361
CAS Number
CAS 13265-10-6
TTD Drug ID
DM5VWOB

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Muscarinic acetylcholine receptor (CHRM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetylcholine DMDF79Z Cataract 9B10 Approved [7]
Tiotropium DMFDC0Q Chronic obstructive pulmonary disease CA22 Approved [8]
Darifenacin DMWXLYZ Overactive bladder GC50.0 Approved [9]
Clidinium DMUMQZ0 Abdominal stomach pain DD91.4 Approved [10]
Oxybutynin hydrochloride DMF2KLU Urinary incontinence MF50.2 Approved [11]
Incruse Ellipta DM32GSJ Chronic obstructive pulmonary disease CA22 Approved [12]
Revefenacin DMMP5SI Chronic obstructive pulmonary disease CA22 Approved [13]
Scopolamine DMOM8AL Addictive disorder 6C50-6C5Z Approved [14]
Isopropamide iodide DMQYV60 Allergic rhinitis CA08.0 Approved [15]
SUN-101 DMXNZQK Chronic obstructive pulmonary disease CA22 Phase 3 [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Muscarinic acetylcholine receptor M2 (CHRM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ACECLIDINE DMOLNCZ Glaucoma/ocular hypertension 9C61 Approved [17]
Methacholine Chloride DMGS4QH Asthma CA23 Approved [18]
SMT-D002 DM1I93C Seborrhea ED91.2 Approved [19]
Gallamine Triethiodide DMPO0MS Stabilize muscle contraction FB3Z Approved [20]
FP-1097 DMC1F2T Urinary incontinence MF50.2 Phase 2 [21]
PSD-506 DMT0KB1 Overactive bladder GC50.0 Discontinued in Phase 2 [22]
Otenzepad DMRXHAC Heart failure BD10-BD13 Discontinued in Phase 2 [23]
SCH-211803 DM92E0W Parkinson disease 8A00.0 Discontinued in Phase 1 [24]
Alvameline DMLN0Y5 Alzheimer disease 8A20 Terminated [25]
HIMBACINE DMGAKD8 N. A. N. A. Terminated [26]
Gallamine Triethiodide DMPO0MS Stabilize muscle contraction FB3Z Approved [6]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Acetylcholine DMDF79Z Cataract 9B10 Approved [44]
Omadacycline DMR2J95 Acute bacterial skin infection 1C41 Approved [45]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [46]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [5]
Bardoxolone methyl DMODA2X Mixed connective tissue disease 4A43.3 Phase 3 [47]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [48]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [49]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Targeting Muscarinic acetylcholine receptor M3 (CHRM3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolterodine DMSHPW8 Overactive bladder GC50.0 Approved [27]
ACECLIDINE DMOLNCZ Glaucoma/ocular hypertension 9C61 Approved [17]
Tiotropium DMFDC0Q Chronic obstructive pulmonary disease CA22 Approved [28]
Ipratropium DMFQ320 Obstructive lung disease CA22.Z Approved [29]
Darifenacin DMWXLYZ Overactive bladder GC50.0 Approved [30]
Methacholine Chloride DMGS4QH Asthma CA23 Approved [31]
SMT-D002 DM1I93C Seborrhea ED91.2 Approved [19]
Solifenacin DMG592Q Overactive bladder GC50.0 Approved [32]
Cevimeline DMWSMND Sjogren syndrome 4A43.20 Approved [33]
Methscopolamine Bromide DMHP8FI Nausea and vomiting MD90 Approved [34]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [38]
Testosterone DM7HUNW Hot flushes GA30 Approved [39]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Acetylcholine DMDF79Z Cataract 9B10 Approved [41]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [41]
Arsenic DMTL2Y1 N. A. N. A. Approved [42]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Affected By Muscarinic acetylcholine receptor M4 (CHRM4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ALCURONIUM DM2U4XQ Anaesthesia 9A78.6 Approved [50]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Acetylcholine DMDF79Z Cataract 9B10 Approved [44]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [50]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [52]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [53]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [48]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [49]
brucine DM50RUD Discovery agent N.A. Investigative [50]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Muscarinic acetylcholine receptor M1 (CHRM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pirenzepine DMP6M1N Peptic ulcer DA61 Approved [54]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [55]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [56]
Acetylcholine DMDF79Z Cataract 9B10 Approved [57]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [41]
Clozapine DMFC71L Schizophrenia 6A20 Approved [58]
Olanzapine DMPFN6Y Bipolar depression Approved [59]
Gallamine Triethiodide DMPO0MS Stabilize muscle contraction FB3Z Approved [60]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [57]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [61]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Muscarinic acetylcholine receptor M5 (CHRM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Acetylcholine DMDF79Z Cataract 9B10 Approved [63]
Gallamine Triethiodide DMPO0MS Stabilize muscle contraction FB3Z Approved [6]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [48]
[3H]QNB DMC1WHR Discovery agent N.A. Investigative [64]
[3H]dimethyl-W84 DMBWAIE Discovery agent N.A. Investigative [6]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Muscarinic acetylcholine receptor (CHRM) TTOXS3C NOUNIPROTAC Antagonist [2]
Muscarinic acetylcholine receptor M2 (CHRM2) TTYEG6Q ACM2_HUMAN Antagonist [3]
Muscarinic acetylcholine receptor M3 (CHRM3) TTQ13Z5 ACM3_HUMAN Antagonist [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Muscarinic acetylcholine receptor M1 (CHRM1) OTKW3E6B ACM1_HUMAN Drug Response [5]
Muscarinic acetylcholine receptor M2 (CHRM2) OTUMZ2WR ACM2_HUMAN Drug Response [6]
Muscarinic acetylcholine receptor M3 (CHRM3) OTKSD095 ACM3_HUMAN Drug Response [5]
Muscarinic acetylcholine receptor M4 (CHRM4) OTF0F0FF ACM4_HUMAN Drug Response [5]
Muscarinic acetylcholine receptor M5 (CHRM5) OTNQRQGG ACM5_HUMAN Drug Response [6]

References

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