Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFXUT8)

Drug Name

Oxymetholone Drug Info

Synonyms

oxymetholone; Anasterone; 434-07-1; HMS3393H15

Indication

Disease Entry	ICD 11	Status	REF
Aplastic anemia	3A70	Approved	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Approved Drug(s)

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Drug(s) Metabolized By Steroid 5-alpha-reductase 1 (SRD5A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Testosterone cypionate	DMC1TEV	Testosterone deficiency	5A81.1	Approved	[3]
Testosterone enanthate	DMB6871	Testosterone deficiency	5A81.1	Approved	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Steroid 5-alpha-reductase 1 (SRD5A1)^{Main DME}	DEOG15F	S5A1_HUMAN	Substrate	[2]

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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Androgen physiology. Semin Reprod Med. 2006 Apr;24(2):71-7.
3	Molecular analysis of the SRD5A1 and SRD5A2 genes in patients with benign prostatic hyperplasia with regard to metabolic parameters and selected hormone levels. Int J Environ Res Public Health. 2017 Oct 30;14(11).