Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMO9HWU)

Drug Name
D-7193 Drug Info
Synonyms D-7042
Indication
Disease Entry ICD 11 Status REF
Immune System disease 4A01-4B41 Discontinued in Phase 2 [1]
Cross-matching ID
PubChem CID
6995101
TTD Drug ID
DMO9HWU

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Prostaglandin G/H synthase (COX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [4]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [5]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [6]
Dexibuprofen DMFYBD0 Ankylosing spondylitis FA92.0 Approved [7]
Ketorolac DMI4EL5 Postoperative inflammation 1A00-CA43.1 Approved [8]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [9]
Oxaprozin DM9UB0P Osteoarthritis FA00-FA05 Approved [10]
Aceclofenac DMZDF0B Inflammation 1A00-CA43.1 Approved [11]
Lornoxicam DMYZFXN Migraine 8A80 Approved [12]
Morniflumate DM9UTDE Otitis media AA80-AB0Z Approved [13]
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Drug(s) Affected By Interleukin-2 receptor subunit alpha (IL2RA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [14]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [15]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [16]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [17]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [18]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [19]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [20]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
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Drug(s) Affected By Receptor-type tyrosine-protein phosphatase C (PTPRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [25]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [26]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [27]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [28]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [29]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [32]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [33]
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Drug(s) Affected By Integrin alpha-M (ITGAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [34]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [35]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [36]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [37]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [38]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [39]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [40]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [41]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [42]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [43]
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Drug(s) Affected By L-selectin (SELL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [44]
Meloxicam DM2AR7L Arthritis FA20 Approved [44]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [35]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [45]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [44]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [46]
Nabumetone DMAT2XH Osteoarthritis FA00-FA05 Approved [44]
Phenylbutazone DMAYL0T Chronic pain MG30 Approved [44]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin G/H synthase (COX) TTK0943 PGH1_HUMAN; PGH2_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Integrin alpha-M (ITGAM) OTAG6HWU ITAM_HUMAN Gene/Protein Processing [3]
Interleukin-2 receptor subunit alpha (IL2RA) OT0MWCHG IL2RA_HUMAN Gene/Protein Processing [3]
L-selectin (SELL) OT6RAJZR LYAM1_HUMAN Gene/Protein Processing [3]
Receptor-type tyrosine-protein phosphatase C (PTPRC) OT6KOR77 PTPRC_HUMAN Gene/Protein Processing [3]

References

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