Details of the Drug Combinations

General Information of This Drug (ID: DMJAPE7)

Drug Name

Methylene blue DMJAPE7

Synonyms

methylene blue; 61-73-4; Methylthioninium chloride; Swiss Blue; Chromosmon; Methylene Blue N; Methylenium ceruleum; Urolene blue; Methylene Blue chloride; Solvent blue 8; Bleu de methylene; Methylene Blue G; Methylene Blue A; External Blue 1; Methylene Blue D; Methylene Blue B; Methylene Blue anhydrous; CI Basic Blue 9; Methylene Blue ZF; Methylene Blue SP; Methylene Blue NZ; Methylene Blue BX; Methylene Blue BD; Methylene Blue SG; Tetramethylene Blue; Methylene Blue ZX; Methylene Blue FZ; Methylene Blue BP; Calcozine; 3,7-Bis-dimethylamino-phenothiazin-5-ylium

Indication

Disease Entry	ICD 11	Status	REF
Acquired methemoglobinemia	3A93	Approved	[1]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[2]
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Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

210 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Abacavir + Methylene blue	DC4ZMZZ	Abacavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Acamprosate + Methylene blue	DCTCYNA	Acamprosate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Acarbose + Methylene blue	DCL92IM	Acarbose	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Acetohexamide + Methylene blue	DC4K9KW	Acetohexamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Aliskiren + Methylene blue	DCWEF2M	Aliskiren	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Alvespimycin hydrochloride + Methylene blue	DCBDZN4	Alvespimycin hydrochloride	DD2 (Cell Line: DD2)	[3]
Amiloride + Methylene blue	DCPEQC0	Amiloride	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Aminosalicylic acid + Methylene blue	DCDKAAJ	Aminosalicylic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Armodafinil + Methylene blue	DCTS6S7	Armodafinil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
AS-1949490 + Methylene blue	DCZOTOM	AS-1949490	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Asenapine + Methylene blue	DC6Z2MH	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Atenolol + Methylene blue	DC7GG9B	Atenolol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Atovaquone + Methylene blue	DC1W2W5	Atovaquone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Atovaquone + Methylene blue	DC75D6M	Atovaquone	Hepatoblastoma (Cell Line: HB3)	[3]
Azelnidipine + Methylene blue	DC3QYM7	Azelnidipine	DD2 (Cell Line: DD2)	[3]
Azelnidipine + Methylene blue	DCV10FT	Azelnidipine	Hepatoblastoma (Cell Line: HB3)	[3]
Benserazide + Methylene blue	DC89OWB	Benserazide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
BHV-0223 + Methylene blue	DC8WRQE	BHV-0223	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Bortezomib + Methylene blue	DCV64VI	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Bosentan + Methylene blue	DCOJYBD	Bosentan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Buspirone + Methylene blue	DC6A5RN	Buspirone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Busulfan + Methylene blue	DCHHJT6	Busulfan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Carglumic acid + Methylene blue	DCJ1M9V	Carglumic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Chlormezanone + Methylene blue	DCUTCH4	Chlormezanone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Chloroquine + Methylene blue	DCPCA17	Chloroquine	DD2 (Cell Line: DD2)	[3]
Chlorphenesin + Methylene blue	DCRHM31	Chlorphenesin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Chlorzoxazone + Methylene blue	DCE5B66	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cilastatin + Methylene blue	DCB8BQ5	Cilastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cilostazol + Methylene blue	DCCRBRR	Cilostazol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cinacalcet + Methylene blue	DCXC8HJ	Cinacalcet	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cisatracurium + Methylene blue	DC3XNAY	Cisatracurium	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Citalopram + Methylene blue	DC6H7RL	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Clascoterone + Methylene blue	DCAGOL1	Clascoterone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Clindamycin + Methylene blue	DC2Z2PX	Clindamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Clindamycin + Methylene blue	DCAWF6D	Clindamycin	DD2 (Cell Line: DD2)	[3]
Clopidogrel + Methylene blue	DCGEG0F	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cycloguanil + Methylene blue	DCKYO08	Cycloguanil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cycloheximide + Methylene blue	DC0ZQCJ	Cycloheximide	DD2 (Cell Line: DD2)	[3]
Cytarabine + Methylene blue	DCCFONG	Cytarabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Darunavir + Methylene blue	DC2JVSO	Darunavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diazoxide + Methylene blue	DCHIMH4	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dichlorphenamide + Methylene blue	DCP23NX	Dichlorphenamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diethylcarbamazine + Methylene blue	DCU3UVB	Diethylcarbamazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dihydroergotamine + Methylene blue	DCNZCS9	Dihydroergotamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diphenidol + Methylene blue	DCRGEGV	Diphenidol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Docetaxel + Methylene blue	DCO37O7	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Methylene blue	DCN9G8M	Dopamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dronedarone + Methylene blue	DC2CUCT	Dronedarone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Efavirenz + Methylene blue	DCQJ0I5	Efavirenz	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Emetine + Methylene blue	DCU2TVP	Emetine	DD2 (Cell Line: DD2)	[3]
Enoxacin + Methylene blue	DCMQRPC	Enoxacin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Entacapone + Methylene blue	DCS7RD0	Entacapone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Eptifibatide + Methylene blue	DC5RAPR	Eptifibatide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ethambutol + Methylene blue	DCTMT54	Ethambutol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ethinyl estradiol + Methylene blue	DC12E4K	Ethinyl estradiol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
ETHISTERONE + Methylene blue	DCVC7OC	ETHISTERONE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Etomidate + Methylene blue	DCR8DVW	Etomidate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fenoprofen + Methylene blue	DCUYPI8	Fenoprofen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fibrates + Methylene blue	DCI92UR	Fibrates	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Flavonoid derivative 1 + Methylene blue	DCA61NW	Flavonoid derivative 1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Furazolidone + Methylene blue	DCI0HY9	Furazolidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Galantamine + Methylene blue	DCQ2BSS	Galantamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
GS4071 + Methylene blue	DCZMMHN	GS4071	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
GSK2126458 + Methylene blue	DC7L795	GSK2126458	Hepatoblastoma (Cell Line: HB3)	[4]
GSK2194069 + Methylene blue	DCXRWZ2	GSK2194069	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Hydralazine + Methylene blue	DCON1MF	Hydralazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Hyodeoxycholic acid + Methylene blue	DC3VDYC	Hyodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ibutilide + Methylene blue	DCHMBVJ	Ibutilide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Iloprost + Methylene blue	DCA0UUF	Iloprost	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Isosorbide dinitrate + Methylene blue	DCQXT65	Isosorbide dinitrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
K-134 + Methylene blue	DCUK7MS	K-134	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Methylene blue	DCKHAMG	Kanamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
KN-62 + Methylene blue	DCJR6WL	KN-62	DD2 (Cell Line: DD2)	[3]
KN-62 + Methylene blue	DC6N1D6	KN-62	Hepatoblastoma (Cell Line: HB3)	[4]
Lefaxin + Methylene blue	DCY0ICH	Lefaxin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Levamisole + Methylene blue	DCLRVOM	Levamisole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
LIAROZOLE + Methylene blue	DC9VGLV	LIAROZOLE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lithium Citrate + Methylene blue	DCLGYCA	Lithium Citrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Loperamide + Methylene blue	DCL0VIZ	Loperamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lubiprostone + Methylene blue	DC6XEGW	Lubiprostone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lumefantrine + Methylene blue	DCKT6R1	Lumefantrine	DD2 (Cell Line: DD2)	[3]
Lumefantrine + Methylene blue	DC7ONP8	Lumefantrine	Hepatoblastoma (Cell Line: HB3)	[3]
LY03004 + Methylene blue	DCVD70S	LY03004	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Maprotiline + Methylene blue	DCLUNCT	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Maraviroc + Methylene blue	DCIPVU5	Maraviroc	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mebendazole + Methylene blue	DCBFD28	Mebendazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mecamylamine + Methylene blue	DC2U3FN	Mecamylamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mefloquine + Methylene blue	DC8251O	Mefloquine	DD2 (Cell Line: DD2)	[3]
Mefloquine + Methylene blue	DC3CKTO	Mefloquine	Hepatoblastoma (Cell Line: HB3)	[3]
Mesalazine + Methylene blue	DCGHXFP	Mesalazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Metaxalone + Methylene blue	DCR48SH	Metaxalone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Metformin + Methylene blue	DCHVV7T	Metformin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methotrexate + Methylene blue	DC20ZB7	Methotrexate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Meclofenamic acid	DCDSM75	Meclofenamic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Sertraline	DCTZ4QW	Sertraline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Mebutamate	DC57H37	Mebutamate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Picoplatin	DCSEKPB	Picoplatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Primidone	DC9RL0L	Primidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Dantrolene	DCEUFA5	Dantrolene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Diethylcarbamazine	DCA2LWY	Diethylcarbamazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Lumefantrine	DCWA7VW	Lumefantrine	DD2 (Cell Line: DD2)	[3]
Methylene blue + Imipramine	DCWVVWC	Imipramine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Crotamiton	DCA487R	Crotamiton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Terazosin	DCIEAHI	Terazosin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + GYKI-52466	DCUTA76	GYKI-52466	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Artemether	DC60NAY	Artemether	DD2 (Cell Line: DD2)	[3]
Methylene blue + Tacrine	DCE3A1F	Tacrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Panobinostat	DCG7G05	Panobinostat	Diffuse intrinsic pontine glioma (Cell Line: DIPG25)	[3]
Methylene blue + Miglustat	DC1O9J1	Miglustat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Ramelteon	DCJBNK2	Ramelteon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Dexmedetomidine	DCWCPMT	Dexmedetomidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + 10-hydroxycamptothecin	DCEJSE8	10-hydroxycamptothecin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Pamidronate	DCDRJ27	Pamidronate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Guanfacine	DC4W5MZ	Guanfacine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + SCH 727965	DC6MVM9	SCH 727965	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Itraconazole	DC9R94I	Itraconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Emetine	DCWYM82	Emetine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Sulfinpyrazone	DC6VIE1	Sulfinpyrazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Daidzin	DCEB4SS	Daidzin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Phensuximide	DC6LLAN	Phensuximide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + VR-776	DCNDME4	VR-776	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Nizatidine	DCU2E1G	Nizatidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Zaleplon	DCXBO2L	Zaleplon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + PHA-739358	DC0BMQK	PHA-739358	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Clopidogrel	DCEOM7U	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Tolazoline	DCPEHOX	Tolazoline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Fenoprofen	DC0P9RS	Fenoprofen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Idarubicin	DCLLTLN	Idarubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Methocarbamol	DCBA277	Methocarbamol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + BRL-15572	DCUM79L	BRL-15572	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Linagliptin	DC1B8ST	Linagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Ethinyl estradiol	DC6P447	Ethinyl estradiol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Artemisinin	DCDVDV3	Artemisinin	DD2 (Cell Line: DD2)	[3]
Methylene blue + Topotecan	DCDN30W	Topotecan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Olanzapine	DCN0TC6	Olanzapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Cefmenoxime	DCZ2TLH	Cefmenoxime	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Maprotiline	DCA85ME	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Novobiocin	DCVX3X0	Novobiocin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Chlorambucil	DCQ6SLO	Chlorambucil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Brincidofovir	DCYJTHC	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Quinine	DC78TMV	Quinine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Piperaquine	DCHCP3A	Piperaquine	DD2 (Cell Line: DD2)	[3]
Methylene blue + Fosfomycin	DCFBXQO	Fosfomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Lacosamide	DCOD7ZM	Lacosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Olmesartan medoxomil	DC65NJ9	Olmesartan medoxomil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Auranofin	DC72V6L	Auranofin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + FORMESTANE	DCJAET8	FORMESTANE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Vorinostat	DC1F912	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Cevimeline	DCPGJSJ	Cevimeline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Hydroxychloroquine	DCXRDE4	Hydroxychloroquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + ML323	DC0FM0V	ML323	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Aciclovir	DCUSYR3	Aciclovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylene blue + Lumefantrine	DCCWZC8	Lumefantrine	Hepatoblastoma (Cell Line: HB3)	[4]
Methylene blue + Artemether	DCC948Y	Artemether	Hepatoblastoma (Cell Line: HB3)	[4]
Methylene blue + Piperaquine	DCSVNK3	Piperaquine	Hepatoblastoma (Cell Line: HB3)	[4]
Metyrosine + Methylene blue	DCKNQM4	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Miconazole + Methylene blue	DCRXY69	Miconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Midostaurin + Methylene blue	DCTLN8G	Midostaurin	DD2 (Cell Line: DD2)	[3]
Midostaurin + Methylene blue	DC5LGQO	Midostaurin	Hepatoblastoma (Cell Line: HB3)	[4]
Moricizine + Methylene blue	DCGJN95	Moricizine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mycophenolic acid + Methylene blue	DC16VR6	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Nabilone + Methylene blue	DCAEXZK	Nabilone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Naltrexone + Methylene blue	DC8DIDH	Naltrexone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Naltrexone + Methylene blue	DC52CYB	Naltrexone	DD2 (Cell Line: DD2)	[3]
Naltrexone + Methylene blue	DCSU77S	Naltrexone	Hepatoblastoma (Cell Line: HB3)	[3]
Naringenin + Methylene blue	DCNVB85	Naringenin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Nitisinone + Methylene blue	DCAE52V	Nitisinone	DD2 (Cell Line: DD2)	[3]
Nitisinone + Methylene blue	DC7BQ21	Nitisinone	Hepatoblastoma (Cell Line: HB3)	[3]
Otilonium bromide + Methylene blue	DCYRB0F	Otilonium bromide	DD2 (Cell Line: DD2)	[3]
Panobinostat + Methylene blue	DC4O7I6	Panobinostat	DD2 (Cell Line: DD2)	[3]
Pargyline + Methylene blue	DCNFJGR	Pargyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Paromomycin + Methylene blue	DC0GR64	Paromomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pazopanib + Methylene blue	DCTQTN0	Pazopanib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pazopanib HCl + Methylene blue	DCMP6U2	Pazopanib HCl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pentamidine + Methylene blue	DCKK9NY	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pentostatin + Methylene blue	DC2ITJ2	Pentostatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pepstatin + Methylene blue	DCDOGGV	Pepstatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PFK-158 + Methylene blue	DCPTBI5	PFK-158	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pinacidil + Methylene blue	DC2M63R	Pinacidil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Piperaquine + Methylene blue	DCBA2E5	Piperaquine	DD2 (Cell Line: DD2)	[3]
Pizotyline + Methylene blue	DC2KMKW	Pizotyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PMID28870136-Compound-43 + Methylene blue	DCHNLWD	PMID28870136-Compound-43	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pomalidomide + Methylene blue	DCZHSOV	Pomalidomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Probenecid + Methylene blue	DCSQ59J	Probenecid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pyrazinamide + Methylene blue	DCJ5XI1	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Quinine + Methylene blue	DCAQRHN	Quinine	DD2 (Cell Line: DD2)	[3]
Quinine + Methylene blue	DCT7HPY	Quinine	Hepatoblastoma (Cell Line: HB3)	[3]
Raltegravir + Methylene blue	DCZU8SN	Raltegravir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Rifampin + Methylene blue	DCSCHBF	Rifampin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Rufinamide + Methylene blue	DCOQV94	Rufinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sitagliptin + Methylene blue	DCHPW6T	Sitagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sitosterol + Methylene blue	DCGN3E9	Sitosterol	DD2 (Cell Line: DD2)	[3]
Sivelestat + Methylene blue	DCUTD3K	Sivelestat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sulfapyridine + Methylene blue	DCS1TTF	Sulfapyridine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sumatriptan + Methylene blue	DC8G8BG	Sumatriptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tamoxifen + Methylene blue	DC4091F	Tamoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Terameprocol + Methylene blue	DCYDA8N	Terameprocol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Teriflunomide + Methylene blue	DCP43UX	Teriflunomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tetracycline + Methylene blue	DC19ZUE	Tetracycline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tiagabine + Methylene blue	DCYF7U7	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tindamax + Methylene blue	DCXOZ0F	Tindamax	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tranexamic acid + Methylene blue	DC9BE2D	Tranexamic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trazodone + Methylene blue	DC9XPC8	Trazodone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Triapine + Methylene blue	DCYJNF1	Triapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[4]
Trifluoperazine + Methylene blue	DCD45QD	Trifluoperazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Triflupromazine + Methylene blue	DCBFYQS	Triflupromazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trihexyphenidyl + Methylene blue	DCAWKLZ	Trihexyphenidyl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Triiodothyronine + Methylene blue	DCAIL5G	Triiodothyronine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trioxsalen + Methylene blue	DCLCQN1	Trioxsalen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Valproic Acid + Methylene blue	DCIXW02	Valproic Acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
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⏷ Show the Full List of 210 DrugCom(s)

4 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Indocyanine green + Methylene blue	DCOVE4I	Indocyanine green	Lymphedema	[5]
Indocyanine green + Methylene blue	DCXPURP	Indocyanine green	Sentinel Lymph Node	[6]
Methylene blue + Vitamin C	DCQ1JJP	Vitamin C	Coronavirus Disease 2019 (COVID-19)	[2]
Phenazopyridine + Methylene blue	DC1FWCT	Phenazopyridine	Mild Cognitive Impairment	[7]
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References

1	Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue. FEBS Lett. 1998 Feb 6;422(3):311-4.
2	ClinicalTrials.gov (NCT04370288) Clinical Application of Methylene Blue for Treatment of Covid-19 Patients. U.S. National Institutes of Health.
3	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4	Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
5	ClinicalTrials.gov (NCT01276054) Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.
6	ClinicalTrials.gov (NCT02084784) Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research
7	ClinicalTrials.gov (NCT02380573) Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease