Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5H2W9)

Drug Name
dioscin Drug Info
Synonyms
Dioscin; 19057-60-4; Collettiside III; Dioscine; CHEBI:74023; CCRIS 4123; UNII-3B95U4OLWV; 3-O-(Rhaalpha1-4(Rhaalpha1-2)Glcbeta)-(25R)-spirost-5-en-3beta-ol; 3-O-[alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc]-diosgenin; 3-O-[alpha-L-Rhap-(1->4)-[alpha-L-Rhap-(1->2)]-beta-D-Glcp]-diosgenin; (25R)-spirost-5-en-3beta-yl alpha-L-rhamnopyranosyl-(1->2)-[alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside; 3B95U4OLWV; AC1L3OGN; Dioscin(Collettiside III); Dioscin (Collettiside III); GTPL840
Indication
Disease Entry ICD 11 Status REF
Hepatic fibrosis DB93.0 Preclinical [1]
Cross-matching ID
PubChem CID
119245
ChEBI ID
CHEMBL74023
CAS Number
CAS 19057-60-4
TTD Drug ID
DM5H2W9
VARIDT Drug ID
DR00897

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Discontinued Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting C-X-C chemokine receptor type 3 (CXCR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
T487 DMZTL7H Psoriatic disorder EA90 Discontinued in Phase 2 [8]
JT07 DMHBWOP Solid tumour/cancer 2A00-2F9Z Preclinical [9]
kallstroemin D DM7YAE0 Discovery agent N.A. Investigative [2]
NBI-74330 DMURC6X Discovery agent N.A. Investigative [8]
Sch-900875 DM346KA Inflammation 1A00-CA43.1 Investigative [10]
hypoglaucin A DMJKIUX Discovery agent N.A. Investigative [2]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [12]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [15]
Selenium DM25CGV N. A. N. A. Approved [16]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [17]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [19]
Gefitinib DM15F0X Colon adenocarcinoma Approved [20]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [21]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [22]
Etretinate DM2CZFA Keratosis ED56 Approved [23]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [25]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [26]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [28]
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Drug(s) Affected By Serine/threonine-protein kinase Chk2 (CHEK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [29]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
Testosterone DM7HUNW Hot flushes GA30 Approved [35]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Capsaicin DMGMF6V Back pain ME84.Z Approved [37]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [38]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [39]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [40]
Gefitinib DM15F0X Colon adenocarcinoma Approved [20]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [41]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Etretinate DM2CZFA Keratosis ED56 Approved [23]
Prednisone DM2HG4X Acute asthma CA23 Approved [43]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [44]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [11]
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Drug(s) Affected By Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [39]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [47]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [51]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [52]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [46]
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Drug(s) Affected By Mitogen-activated protein kinase 8 (MAPK8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [53]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [59]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [60]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [57]
Ethacrynic acid DM60QMR Edema MG29 Approved [61]
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Drug(s) Affected By Mitogen-activated protein kinase 9 (MAPK9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [57]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Sorbitol DMAN0DE Constipation DD91.1 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
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Drug(s) Affected By Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [72]
Leflunomide DMR8ONJ Arthritis FA20 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [74]
Menthol DMG2KW7 Back pain ME84.Z Approved [75]
Hesperidin DMI5DW1 Vascular purpura 3B60 Approved [76]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 25 (TNFRSF25)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [78]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [72]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Menthol DMG2KW7 Back pain ME84.Z Approved [75]
Capsaicin DMGMF6V Back pain ME84.Z Approved [37]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2-binding component 3, isoforms 3/4 (BBC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [22]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [24]
Methotrexate DM2TEOL Anterior urethra cancer Approved [79]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [80]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [81]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [82]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [83]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [84]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [85]
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Drug(s) Affected By Diablo IAP-binding mitochondrial protein (DIABLO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [22]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [91]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [92]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [93]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [74]
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Drug(s) Affected By 5'-AMP-activated protein kinase subunit beta-1 (PRKAB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [94]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [95]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [95]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [95]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [96]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [97]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [11]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [11]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [50]
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Drug(s) Affected By Apoptotic protease-activating factor 1 (APAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [99]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [100]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [101]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [102]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase Chk1 (CHEK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Methotrexate DM2TEOL Anterior urethra cancer Approved [103]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [104]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [107]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [108]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [109]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [110]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [111]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [112]
Cepharanthine DM9Y5JB N. A. N. A. Approved [113]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [114]
Clozapine DMFC71L Schizophrenia 6A20 Approved [115]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [116]
Trifluoperazine DMKBYWI Anxiety Approved [117]
Olanzapine DMPFN6Y Bipolar depression Approved [115]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [118]
Gefitinib DM15F0X Colon adenocarcinoma Approved [119]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [22]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [121]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [44]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [121]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [122]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [123]
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [52]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [126]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [128]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [129]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [130]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [131]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [132]
Epinephrine DM3KJBC Acute asthma CA23 Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [134]
Fructose DM43AN2 Vomiting MD90 Approved [135]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [131]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [136]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [137]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [139]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [140]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [141]
Testosterone DM7HUNW Hot flushes GA30 Approved [142]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [143]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Prednisone DM2HG4X Acute asthma CA23 Approved [43]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [144]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [145]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [146]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [147]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [148]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [149]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [150]
Gefitinib DM15F0X Colon adenocarcinoma Approved [151]
Prednisone DM2HG4X Acute asthma CA23 Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [152]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [153]
Quercetin DM3NC4M Obesity 5B81 Approved [154]
Fluoxetine DM3PD2C Bipolar depression Approved [155]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Gefitinib DM15F0X Colon adenocarcinoma Approved [158]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [159]
Epinephrine DM3KJBC Acute asthma CA23 Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [160]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [161]
Fructose DM43AN2 Vomiting MD90 Approved [135]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [162]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [163]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [164]
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Drug(s) Affected By BH3-interacting domain death agonist (BID)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [22]
Selenium DM25CGV N. A. N. A. Approved [16]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [167]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [91]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
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Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [169]
Gefitinib DM15F0X Colon adenocarcinoma Approved [119]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [171]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [172]
Methotrexate DM2TEOL Anterior urethra cancer Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [174]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [175]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [176]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [22]
Selenium DM25CGV N. A. N. A. Approved [178]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [179]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [180]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [181]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [161]
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Drug(s) Affected By TNF receptor-associated factor 1 (TRAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [182]
Methotrexate DM2TEOL Anterior urethra cancer Approved [183]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [129]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [184]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [185]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [96]
Folic Acid DMEMBJC Colorectal carcinoma Approved [186]
Menthol DMG2KW7 Back pain ME84.Z Approved [75]
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Drug(s) Affected By FAS-associated death domain protein (FADD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [118]
Selenium DM25CGV N. A. N. A. Approved [187]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [188]
Quercetin DM3NC4M Obesity 5B81 Approved [189]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [165]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [128]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [72]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [92]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2 homologous antagonist/killer (BAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [62]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [192]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [193]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Levamisole DM5EN79 Parasitic infection 1D0Y-1G2Z Approved [194]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [195]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [196]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [197]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl2-associated agonist of cell death (BAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [198]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [199]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [200]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [201]
Quercetin DM3NC4M Obesity 5B81 Approved [202]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [203]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [204]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-X-C chemokine receptor type 3 (CXCR3) TT1UCIJ CXCR3_HUMAN Antagonist [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5'-AMP-activated protein kinase subunit beta-1 (PRKAB1) OT1OG4QZ AAKB1_HUMAN Gene/Protein Processing [3]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Gene/Protein Processing [4]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [5]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [3]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Gene/Protein Processing [6]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Gene/Protein Processing [3]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [6]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Gene/Protein Processing [4]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Gene/Protein Processing [6]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [7]

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118 Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma. Sci Rep. 2020 Nov 26;10(1):20622. doi: 10.1038/s41598-020-77674-y.
119 Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells. Chem Biol Interact. 2013 Apr 25;203(2):412-22. doi: 10.1016/j.cbi.2013.03.011. Epub 2013 Mar 22.
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