General Information of Drug (ID: DM6WPIS)

Drug Name
L-serine Drug Info
Synonyms
L-serine; serine; 56-45-1; (S)-2-Amino-3-hydroxypropanoic acid; H-Ser-OH; (S)-Serine; beta-Hydroxyalanine; L-ser; L-(-)-Serine; Polyserine; Serine, L-; (2S)-2-amino-3-hydroxypropanoic acid; L-3-Hydroxy-alanine; Poly-L-serine; 2-Amino-3-hydroxypropionic acid; beta-Hydroxy-L-alanine; Serinum [Latin]; Serina [Spanish]; L-2-Amino-3-hydroxypropionic acid; Serine (VAN); L-3-Hydroxy-2-aminopropionic acid; Serine [USAN:INN]; SER (IUPAC abbrev); 3-Hydroxyalanine; L-Serin; (S)-(-)-Serine; (-)-Serine; alpha-Amino-beta-hydroxypropionic acid
Indication
Disease Entry ICD 11 Status REF
Pulmonary tuberculosis 1B10.Z Approved [1]
Discovery agent N.A. Investigative [2]
Cross-matching ID
PubChem CID
5951
ChEBI ID
CHEMBL11298
CAS Number
CAS 56-45-1
TTD Drug ID
DM6WPIS
VARIDT Drug ID
DR01005

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Approved Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-citrulline DMT4K0Z Acute lung injury NB32.3 Phase 3 [3]
L-ornithine DMHKGCM Discovery agent N.A. Investigative [3]
L-lysine DMOD5CK Discovery agent N.A. Investigative [3]
calindol DMY9P6E Discovery agent N.A. Investigative [5]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [6]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [7]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [8]
Methotrexate DM2TEOL Anterior urethra cancer Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [13]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [14]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [16]
Etretinate DM2CZFA Keratosis ED56 Approved [17]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [16]
Quercetin DM3NC4M Obesity 5B81 Approved [18]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [19]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [21]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [16]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [22]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [7]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [23]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [24]
Selenium DM25CGV N. A. N. A. Approved [25]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [26]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [27]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [28]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [29]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [30]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [31]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [16]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [27]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [34]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [29]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [16]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [35]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [36]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [37]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [38]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [42]
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Drug(s) Affected By Calnexin (CANX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [21]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [22]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [44]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [45]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [49]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [52]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [53]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [49]
Isoproterenol DMK7MEY Atrioventricular block Approved [55]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [56]
Teriflunomide DMQ2FKJ Hyperlipidaemia 5C80 Approved [57]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [49]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [58]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [59]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [60]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [61]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [62]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [63]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Panobinostat DM58WKG Chronic graft versus host disease Approved [64]
Sorbitol DMAN0DE Constipation DD91.1 Approved [65]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [66]
Ethanol DMDRQZU Chronic pain MG30 Approved [67]
Dicumarol DMFQCB1 Bleeding disorder GA20-GA21 Approved [65]
Menthol DMG2KW7 Back pain ME84.Z Approved [68]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [69]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [70]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [65]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ataxin-3 (ATXN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [56]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [42]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [73]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [58]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine protease HTRA4 (HTRA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [75]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [76]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [77]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [79]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [79]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [80]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [81]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [79]
Ethacrynic acid DM60QMR Edema MG29 Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [82]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [21]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [83]
Testosterone DM7HUNW Hot flushes GA30 Approved [84]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [85]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [87]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [6]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [7]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [10]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [29]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [14]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [89]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Racecadotril DMFOTZ7 Diarrhea ME05.1 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [91]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [91]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [92]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [56]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [93]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [94]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [76]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [49]
Benzatropine DMF7EXL Parkinsonian disorder Approved [95]
Clozapine DMFC71L Schizophrenia 6A20 Approved [95]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [96]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [97]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [59]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [98]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [62]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [99]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [100]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [101]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Folic Acid DMEMBJC Colorectal carcinoma Approved [102]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [103]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [104]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [98]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [76]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [49]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [94]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [64]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [105]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [106]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [107]
Milchsaure DM462BT Pruritus EC90 Investigative [108]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [23]
Quercetin DM3NC4M Obesity 5B81 Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [109]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [111]
Cerulenin DM6N4PR Weight loss MG43.5 Approved [112]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [113]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [101]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Derlin-2 (DERL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [56]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [105]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [63]
⏷ Show the Full List of 7 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Testosterone enanthate DMB6871 N. A. N. A. Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Bortezomib DMNO38U Leukemia Approved [115]
Indomethacin DMSC4A7 Bursitis Approved [116]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [76]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [106]
Okadaic acid DM47CO1 Discovery agent N.A. Investigative [117]
⏷ Show the Full List of 8 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [29]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [14]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [38]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [119]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [38]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
G-protein coupled receptor GPCR33 (GPRC6A) TTI1PRE GPC6A_HUMAN Agonist [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Ataxin-3 (ATXN3) OTJVVGKT ATX3_HUMAN Gene/Protein Processing [4]
Calnexin (CANX) OTYP1F6J CALX_HUMAN Gene/Protein Processing [4]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Gene/Protein Processing [4]
Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) OTAFHAVI ATF6A_HUMAN Gene/Protein Processing [4]
Cyclic AMP-dependent transcription factor ATF-6 beta (ATF6B) OTT2ZGSR ATF6B_HUMAN Gene/Protein Processing [4]
Derlin-2 (DERL2) OTI3TUUZ DERL2_HUMAN Gene/Protein Processing [4]
DnaJ homolog subfamily B member 2 (DNAJB2) OTZHPV5M DNJB2_HUMAN Gene/Protein Processing [4]
DnaJ homolog subfamily B member 9 (DNAJB9) OT38EQT6 DNJB9_HUMAN Gene/Protein Processing [4]
DnaJ homolog subfamily C member 3 (DNAJC3) OT7ROIJF DNJC3_HUMAN Gene/Protein Processing [4]
DnaJ homolog subfamily C member 4 (DNAJC4) OT4BUBQU DNJC4_HUMAN Gene/Protein Processing [4]

References

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2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 726).
3 Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids. Mol Pharmacol. 2005 Mar;67(3):589-97.
4 Mechanisms of L-Serine Neuroprotection in vitro Include ER Proteostasis Regulation. Neurotox Res. 2018 Jan;33(1):123-132. doi: 10.1007/s12640-017-9829-3. Epub 2017 Nov 2.
5 Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor. Cell Calcium. 2009 Nov-Dec;46(5-6):323-32.
6 Inhibiting Heat Shock Proteins Can Potentiate the Cytotoxic Effect of Cannabidiol in Human Glioma Cells. Anticancer Res. 2015 Nov;35(11):5827-37.
7 Sertraline induces endoplasmic reticulum stress in hepatic cells. Toxicology. 2014 Aug 1;322:78-88. doi: 10.1016/j.tox.2014.05.007. Epub 2014 May 24.
8 Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions. BMC Genomics. 2008 Aug 7;9:376.
9 Methotrexate modulates folate phenotype and inflammatory profile in EA.hy 926 cells. Eur J Pharmacol. 2014 Jun 5;732:60-7.
10 Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells. Mutagenesis. 2011 Sep;26(5):593-604.
11 Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells. World J Gastroenterol. 2009 Jan 21;15(3):310-20.
12 Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Toxicol Appl Pharmacol. 2012 Jun 1;261(2):204-16.
13 Keratinocyte-derived IL-36gama plays a role in hydroquinone-induced chemical leukoderma through inhibition of melanogenesis in human epidermal melanocytes. Arch Toxicol. 2019 Aug;93(8):2307-2320.
14 Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells. Lipids Health Dis. 2010 Jun 2;9:56. doi: 10.1186/1476-511X-9-56.
15 Single-cell Transcriptome Mapping Identifies Common and Cell-type Specific Genes Affected by Acute Delta9-tetrahydrocannabinol in Humans. Sci Rep. 2020 Feb 26;10(1):3450. doi: 10.1038/s41598-020-59827-1.
16 Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell Biol Toxicol. 2021 Apr;37(2):151-175. doi: 10.1007/s10565-020-09537-1. Epub 2020 Jun 14.
17 Consequences of the natural retinoid/retinoid X receptor ligands action in human breast cancer MDA-MB-231 cell line: Focus on functional proteomics. Toxicol Lett. 2017 Nov 5;281:26-34. doi: 10.1016/j.toxlet.2017.09.001. Epub 2017 Sep 5.
18 Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells. Proteomics. 2004 Jul;4(7):2160-74.
19 Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicol In Vitro. 2017 Mar;39:93-103.
20 Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.
21 Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines. Cancer Res. 2005 Dec 15;65(24):11676-88.
22 Essential role of cell cycle regulatory genes p21 and p27 expression in inhibition of breast cancer cells by arsenic trioxide. Med Oncol. 2011 Dec;28(4):1225-54.
23 Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation. Neuro Oncol. 2011 Mar;13(3):267-79. doi: 10.1093/neuonc/noq195. Epub 2011 Feb 3.
24 Microarray analysis of H2O2-, HNE-, or tBH-treated ARPE-19 cells. Free Radic Biol Med. 2002 Nov 15;33(10):1419-32.
25 Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst. 2009 Mar 4;101(5):306-20.
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