Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMV0RNS)

Drug Name
Deflazacort Drug Info
Synonyms C25H33NO6; Deflazacort (Calcort); Deflazacortum [INN-Latin]; EINECS 238-483-7; Deflan (TN); D09WYX; AC1L1BQ2; Deflazacort [USAN:BAN:INN]; CTK8F9001; MolPort-035-394-927
Indication
Disease Entry ICD 11 Status REF
Duchenne dystrophy 8C70 Approved [1]
Cross-matching ID
PubChem CID
189821
ChEBI ID
CHEBI:135720
CAS Number
CAS 14484-47-0
TTD Drug ID
DMV0RNS
VARIDT Drug ID
DR00146
INTEDE Drug ID
DR0430
ACDINA Drug ID
D00174

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [6]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [2]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [7]
Fluticasone DMGCSVF Allergic rhinitis CA08.0 Approved [8]
Betamethasone Valerate DMMIAXO Dermatological disease DA24.Y Approved [2]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [2]
Prednisone DM2HG4X Acute asthma CA23 Approved [9]
Budesonide DMJIBAW Allergic rhinitis CA08.0 Approved [10]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [11]
Fluocinolone Acetonide DMG2KI4 Choroiditis Approved [2]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [28]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Selenium DM25CGV N. A. N. A. Approved [31]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
Quercetin DM3NC4M Obesity 5B81 Approved [34]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [13]
Methotrexate DM2TEOL Anterior urethra cancer Approved [14]
Folic Acid DMEMBJC Colorectal carcinoma Approved [15]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [14]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [16]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [14]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [18]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [20]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [21]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [22]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [24]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [25]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [26]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [20]
Verapamil DMA7PEW Angina pectoris BA40 Approved [27]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucocorticoid receptor (NR3C1) TTYRL6O GCR_HUMAN Modulator [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Gene/Protein Processing [5]

References

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