General Information of Drug (ID: DM2G9AE)

Drug Name
Citalopram Drug Info
Synonyms
Akarin; Celapram; Celexa; Celius; Ciazil; Cilift; Cipram; Ciprapine; Citabax; Citadur; Citalec; Citalopramum; Citopam; Cytalopram; Dalsan; Humorup; Nitalapram; Oropram; Pramcit; Recital; Seropram; Talam; Talohexal; Temperax; Vodelax; Zentius; Zetalo; Citalopram [Celexa]; [3H]Citalopram; Akarin (TN); Celapram (TN); Celexa (TN); Celius (TN); Ciazil (TN); Cilift (TN); Cipram (TN); Cipramil (TN); Ciprapine (TN); Citabax (TN); Citadur (TN); Citalec (TN); Citalopram [INN:BAN]; Citalopramum [INN-Latin]; Citaxin (TN); Citol (TN); Citopam (TN); Citox (TN); Citrol (TN); Dalsan (TN); Lu 10-171; Recital (TN); Seropram (TN); Talam (TN); Zentius (TN); Zetalo (TN); AE-641/00603021; Citalopram (USP/INN); Lu-10-171; 1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile; 1,3-dihydro[3,4]benzofuran-5-carbonitrile; 1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
Indication
Disease Entry ICD 11 Status REF
Acute coronary syndrome BA41 Approved [1]
Anxiety Approved [1]
Depression 6A70-6A7Z Approved [2]
Insomnia 7A00-7A0Z Approved [1]
Lung cancer 2C25.0 Approved [1]
Major depressive disorder 6A70.3 Approved [1]
Colon cancer 2B90.Z Investigative [1]
Gastric cancer 2B72 Investigative [1]
Therapeutic Class
Antidepressants
Cross-matching ID
PubChem CID
2771
ChEBI ID
CHEMBL77397
CAS Number
CAS 59729-33-8
TTD Drug ID
DM2G9AE
VARIDT Drug ID
DR00319
INTEDE Drug ID
DR0334
ACDINA Drug ID
D00133

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [18]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [19]
Fluoxetine DM3PD2C Bipolar depression Approved [3]
Vortioxetine DM6F1PU Major depressive disorder 6A70.3 Approved [20]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [21]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [22]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [23]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [3]
Trazodone DMK1GBJ Depression 6A70-6A7Z Approved [3]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [3]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [24]
Methotrexate DM2TEOL Anterior urethra cancer Approved [25]
Folic Acid DMEMBJC Colorectal carcinoma Approved [26]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [28]
Verapamil DMA7PEW Angina pectoris BA40 Approved [29]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [30]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [31]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [32]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [33]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [29]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Folic Acid DMEMBJC Colorectal carcinoma Approved [36]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [35]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [35]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [37]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [35]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [38]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [39]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [40]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [41]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [42]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [43]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [29]
Verapamil DMA7PEW Angina pectoris BA40 Approved [44]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [45]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [46]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [4]
Propranolol DM79NTF Angina pectoris BA40 Approved [47]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [48]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [49]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [50]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [51]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [52]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [53]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [54]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [55]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [49]
Verapamil DMA7PEW Angina pectoris BA40 Approved [56]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [57]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [58]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [59]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [52]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [56]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [60]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [61]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [62]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [63]
Propranolol DM79NTF Angina pectoris BA40 Approved [64]
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Drug(s) Metabolized By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [65]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [66]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [67]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [68]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [69]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [70]
Verapamil DMA7PEW Angina pectoris BA40 Approved [71]
Estrone DM5T6US Acne vulgaris ED80 Approved [72]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [73]
Ethanol DMDRQZU Chronic pain MG30 Approved [74]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [75]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [76]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [77]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [78]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [71]
Verapamil DMA7PEW Angina pectoris BA40 Approved [79]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [80]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [81]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [82]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [83]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [84]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [85]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [86]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [87]
Capsaicin DMGMF6V Back pain ME84.Z Approved [88]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [89]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [90]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [89]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [85]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [91]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [92]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [93]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [94]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [95]
Cepharanthine DM9Y5JB N. A. N. A. Approved [96]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [97]
Clozapine DMFC71L Schizophrenia 6A20 Approved [98]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [99]
Trifluoperazine DMKBYWI Anxiety Approved [100]
Olanzapine DMPFN6Y Bipolar depression Approved [98]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [101]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [102]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [103]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [102]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Fluoxetine DM3PD2C Bipolar depression Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [103]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [103]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [102]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [106]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [102]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [102]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [107]
Fluoxetine DM3PD2C Bipolar depression Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [108]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [102]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [109]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [110]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [111]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [102]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [102]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Fluoxetine DM3PD2C Bipolar depression Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [113]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
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Drug(s) Affected By Inhibin beta E chain (INHBE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [102]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [102]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Fluoxetine DM3PD2C Bipolar depression Approved [102]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [115]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [103]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [102]
Panobinostat DM58WKG Chronic graft versus host disease Approved [116]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [103]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [102]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [102]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [103]
Fluoxetine DM3PD2C Bipolar depression Approved [103]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [102]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [117]
Testosterone DM7HUNW Hot flushes GA30 Approved [118]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [118]
Haloperidol DM96SE0 Delirium Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [119]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [12]
Fluoxetine DM3PD2C Bipolar depression Approved [12]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [120]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [122]
Testosterone DM7HUNW Hot flushes GA30 Approved [118]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [123]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Clomipramine DMINRKW Depression 6A70-6A7Z Approved [12]
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Drug(s) Affected By Stearoyl-CoA desaturase (SCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [126]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [107]
Fluoxetine DM3PD2C Bipolar depression Approved [17]
Fructose DM43AN2 Vomiting MD90 Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [17]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [130]
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Drug(s) Affected By Pro-opiomelanocortin (POMC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prednisone DM2HG4X Acute asthma CA23 Approved [131]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [132]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [133]
Fentanyl DM8WAHT Analgesia MB40.8 Approved [134]
Cyproheptadine DM92AH3 Allergic rhinitis CA08.0 Approved [135]
Triamcinolone DM98IXF Acute adrenal insufficiency Approved [136]
Buspirone DMBS632 Anxiety disorder 6B00-6B0Z Approved [137]
Ethanol DMDRQZU Chronic pain MG30 Approved [138]
Metyrapone DMI7FVQ Cushing disease 5A70 Approved [139]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [140]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [101]
Gefitinib DM15F0X Colon adenocarcinoma Approved [141]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [142]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [143]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [144]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [145]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [146]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [147]
Methotrexate DM2TEOL Anterior urethra cancer Approved [148]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [149]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [17]
Quercetin DM3NC4M Obesity 5B81 Approved [153]
Fluoxetine DM3PD2C Bipolar depression Approved [17]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [154]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [115]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [155]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [156]
Amphetamine DMSZQAK Attention deficit hyperactivity disorder 6A05.Z Approved [157]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [158]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [159]
Testosterone DM7HUNW Hot flushes GA30 Approved [118]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [118]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [160]
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder 6A05.Z Approved [161]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [162]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [163]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [164]
Fluoxetine DM3PD2C Bipolar depression Approved [165]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [166]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [167]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [168]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Aripiprazole DM3NUMH Bipolar I disorder Approved [169]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [162]
Interferon gamma-1b DMWUMRL Chronic granulomatous disease 4A00.0Y Approved [91]
Chlorothiazide DMLHESP Chronic heart failure BD1Z Approved [170]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [171]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [172]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [173]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [91]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [120]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [174]
Haloperidol DM96SE0 Delirium Approved [174]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [160]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [175]
Olanzapine DMPFN6Y Bipolar depression Approved [176]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [177]
Arsenic DMTL2Y1 N. A. N. A. Approved [178]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [179]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Modulator [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [4]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [5]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [7]
Cytochrome P450 2E1 (CYP2E1) DEVDYN7 CP2E1_HUMAN Substrate [8]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [9]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [10]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5-hydroxytryptamine receptor 2A (HTR2A) OTWXJX0M 5HT2A_HUMAN Drug Response [11]
5-hydroxytryptamine receptor 2C (HTR2C) OT6H8DE0 5HT2C_HUMAN Protein Interaction/Cellular Processes [12]
Alpha-1-antichymotrypsin (SERPINA3) OT9BP2S0 AACT_HUMAN Gene/Protein Processing [13]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Drug Response [14]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Biotransformations [15]
Glutamate receptor ionotropic, NMDA 3A (GRIN3A) OTQS9GYY NMD3A_HUMAN Drug Response [16]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) OTCO26FV HMCS1_HUMAN Gene/Protein Processing [17]
Inhibin beta E chain (INHBE) OTOI2NYG INHBE_HUMAN Gene/Protein Processing [13]
Lysophospholipase D GDPD3 (GDPD3) OTOHM9QM GDPD3_HUMAN Gene/Protein Processing [13]
Nuclear protein 1 (NUPR1) OT4FU8C0 NUPR1_HUMAN Gene/Protein Processing [13]

References

1 Citalopram FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7547).
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
4 Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences. Drug Metab Pharmacokinet. 2008;23(4):243-53.
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