Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMD1B8Z)

Drug Name
Dobutamine Drug Info
Synonyms
Dobutamina; Dobutaminum; Dobutamine Hcl; Dobutamine [USAN]; Dobutamine hydrobromide; LY 81929; Lilly 81929; DL-dobutamine; Dobutamina [INN-Spanish]; Dobutamine Hcl in Dextrose 5%; Dobutamine(usp); Dobutaminum [INN-Latin]; Rac-dobutamine; Racemic-Dobutamine; Dobutamine (USP/INN); Dobutamine [USAN:BAN:INN]; Dobutamine Tartrate (1:1), (S-(R*,R*))-Isomer; (+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol; 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine; 4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzene-1,2-diol; 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol; 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
Indication
Disease Entry ICD 11 Status REF
Heart failure BD10-BD13 Approved [1]
Therapeutic Class
Cardiotonic Agents
Cross-matching ID
PubChem CID
36811
ChEBI ID
CHEBI:4670
CAS Number
CAS 34368-04-2
TTD Drug ID
DMD1B8Z
INTEDE Drug ID
DR1758

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Adrenergic receptor beta-1 (ADRB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propranolol DM79NTF Angina pectoris BA40 Approved [13]
Epinephrine DM3KJBC Acute asthma CA23 Approved [14]
Norepinephrine DMOUC09 Alopecia ED70 Approved [15]
Atenolol DMNKG1Z Angina pectoris BA40 Approved [16]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [16]
Metoprolol DMOJ0V6 Acute coronary syndrome BA41 Approved [16]
Timolol DM3NXRU High blood pressure BA00 Approved [17]
Isoproterenol DMK7MEY Atrioventricular block Approved [18]
Betaxolol DM6EUL5 Hypertension BA00-BA04 Approved [19]
Sotalol DML60TN Sinus rhythm disorder BC9Y Approved [20]
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Drug(s) Metabolized By Catechol O-methyltransferase (COMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [21]
Epinephrine DM3KJBC Acute asthma CA23 Approved [22]
METHYLENEDIOXYMETHAMPHETAMINE DMYVU47 Discovery agent N.A. Investigative [23]
Epinephrine DM3KJBC Acute asthma CA23 Approved [9]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [9]
Modafinil DMYILBE Malignant glioma 2A00.0 Approved [24]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [9]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [30]
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Drug(s) Affected By Beta-1 adrenergic receptor (ADRB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [31]
Methotrexate DM2TEOL Anterior urethra cancer Approved [32]
Vortioxetine DM6F1PU Major depressive disorder 6A70.3 Approved [33]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [34]
Labetalol DMK8U72 Hypertension BA00-BA04 Approved [35]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [36]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [37]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [38]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [39]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [40]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [41]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [41]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [42]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [40]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [41]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [7]
Gefitinib DM15F0X Colon adenocarcinoma Approved [40]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [43]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [40]
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Drug(s) Affected By Renin (REN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [44]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [45]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [46]
Reboxetine DM26PRD Depression 6A70-6A7Z Approved [47]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [48]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [49]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [50]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [51]
Epinephrine DM3KJBC Acute asthma CA23 Approved [52]
Chlorthalidone DM4DMBT Edema MG29 Approved [53]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Gefitinib DM15F0X Colon adenocarcinoma Approved [56]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [11]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [57]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [11]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [58]
Selenium DM25CGV N. A. N. A. Approved [59]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [60]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [61]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [62]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [63]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [64]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [65]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [66]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [67]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [58]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [68]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [69]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [70]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [71]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [65]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [72]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [11]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [57]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [73]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tissue factor (F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [76]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [77]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [78]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Fructose DM43AN2 Vomiting MD90 Approved [80]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [75]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [82]
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Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [83]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [84]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [85]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [87]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [88]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [89]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [25]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [11]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [90]
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Drug(s) Affected By Leptin (LEP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [66]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [67]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [91]
Quercetin DM3NC4M Obesity 5B81 Approved [92]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [93]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [66]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [66]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [94]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [95]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [96]
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Drug(s) Affected By Tumor necrosis factor-inducible gene 6 protein (TNFAIP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Selenium DM25CGV N. A. N. A. Approved [59]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [11]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [100]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [11]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [11]
Trihexyphenidyl DMB19L8 Dystonia 8A02 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
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Drug(s) Affected By Potassium voltage-gated channel subfamily H member 2 (KCNH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [101]
Quinidine DMLPICK N. A. N. A. Approved [102]
Verapamil DMA7PEW Angina pectoris BA40 Approved [103]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [104]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [104]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [105]
Propranolol DM79NTF Angina pectoris BA40 Approved [106]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [107]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [108]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [104]
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Drug(s) Affected By Bile acid receptor (NR1H4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [110]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [113]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [114]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [110]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [111]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [115]
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Drug(s) Affected By Fibroblast growth factor 2 (FGF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [116]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Diazepam DM08E9O Alcohol withdrawal Approved [118]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [119]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [120]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Isradipine DMA5XGH Hypertension BA00-BA04 Approved [123]
Valdecoxib DMAY7H4 Osteoarthritis FA00-FA05 Approved [124]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [125]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [126]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [127]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [128]
Gefitinib DM15F0X Colon adenocarcinoma Approved [129]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [131]
Selenium DM25CGV N. A. N. A. Approved [132]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [133]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [134]
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Drug(s) Affected By Kallikrein-1 (KLK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [135]
Magnesium DMU4ORS Ischemic stroke 8B11.5Z Approved [136]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [137]
AMG 386 DMQJXL4 Breast cancer 2C60-2C65 Phase 3 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [138]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [139]
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Drug(s) Affected By Nitric oxide synthase, inducible (NOS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [38]
Indomethacin DMSC4A7 Bursitis Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [142]
Methotrexate DM2TEOL Anterior urethra cancer Approved [143]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [144]
Quercetin DM3NC4M Obesity 5B81 Approved [145]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [146]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [147]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [148]
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Drug(s) Affected By Neuroendocrine secretory protein 55 (GNAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Selenium DM25CGV N. A. N. A. Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Panobinostat DM58WKG Chronic graft versus host disease Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [150]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [151]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [30]
Clozapine DMFC71L Schizophrenia 6A20 Approved [152]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [153]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [154]
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Drug(s) Affected By Beta-2 adrenergic receptor (ADRB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salmeterol DMIEU69 Allergic asthma CA23.0 Approved [155]
Bambuterol DMKLSHF Asthma CA23 Approved [156]
Terbutaline DMD4381 Asthma CA23 Approved [157]
Salbutamol DMN9CWF Acute asthma CA23 Approved [158]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [159]
Methotrexate DM2TEOL Anterior urethra cancer Approved [32]
Epinephrine DM3KJBC Acute asthma CA23 Approved [160]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [161]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [162]
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Drug(s) Affected By Cardiac phospholamban (PLN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [163]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [164]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [38]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [165]
Manganese DMKT129 N. A. N. A. Investigative [166]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor beta-1 (ADRB1) TTR6W5O ADRB1_HUMAN Agonist [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Catechol O-methyltransferase (COMT) Main DME DEV3T4A COMT_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Beta-1 adrenergic receptor (ADRB1) OTQBWN4U ADRB1_HUMAN Drug Response [4]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Drug Response [5]
Bile acid receptor (NR1H4) OTWZLPTB NR1H4_HUMAN Gene/Protein Processing [6]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [7]
Cardiac phospholamban (PLN) OTT3RRJN PPLA_HUMAN Drug Response [8]
Catechol O-methyltransferase (COMT) OTPWKTQG COMT_HUMAN Biotransformations [9]
Fibroblast growth factor 2 (FGF2) OT7YUJ9F FGF2_HUMAN Drug Response [10]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Gene/Protein Processing [11]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Gene/Protein Processing [12]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [11]

References

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2 Beta-adrenoceptor alterations coupled with secretory response and experimental periodontitis in rat submandibular glands. Arch Oral Biol. 2008 Jun;53(6):509-16.
3 Catechol-O-methyltransferase: substrate-specificity and stereoselectivity for beta-adrenoceptor agents. Xenobiotica. 1986 Jan;16(1):47-52.
4 The Arg389Gly 1-adrenoceptor gene polymorphism influences the acute effects of -adrenoceptor blockade on contractility in the human heart. Clin Res Cardiol. 2011 Aug;100(8):641-7. doi: 10.1007/s00392-011-0288-1. Epub 2011 Feb 11.
5 A bivariate functional mapping model for identifying haplotypes that control drug response for systolic and diastolic blood pressures. Pac Symp Biocomput. 2006:572-83.
6 Investigation of imatinib and other approved drugs as starting points for antidiabetic drug discovery with FXR modulating activity. Biochem Pharmacol. 2012 Jun 15;83(12):1674-81. doi: 10.1016/j.bcp.2012.02.027. Epub 2012 Mar 7.
7 Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. Chem Res Toxicol. 2017 May 15;30(5):1219-1229. doi: 10.1021/acs.chemrestox.7b00048. Epub 2017 May 4.
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10 Gene therapy in cardiac surgery: intramyocardial injection of naked plasmid DNA for chronic myocardial ischemia. Eur J Cardiothorac Surg. 2003 Nov;24(5):785-93. doi: 10.1016/s1010-7940(03)00455-x.
11 An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury. Arch Toxicol. 2021 Jan;95(1):149-168. doi: 10.1007/s00204-020-02882-4. Epub 2020 Aug 20.
12 Myocardial ischemia induces interleukin-6 and tissue factor production in patients with coronary artery disease: a dobutamine stress echocardiography study. Circulation. 2005 Nov 22;112(21):3272-9. doi: 10.1161/CIRCULATIONAHA.104.532259. Epub 2005 Nov 14.
13 Beta-blockers in the treatment of hypertension: are there clinically relevant differences Postgrad Med. 2009 May;121(3):90-8.
14 Adrenergic activation of electrogenic K+ secretion in guinea pig distal colonic epithelium: involvement of beta1- and beta2-adrenergic receptors. Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G269-77.
15 Impact of exogenous beta-adrenergic receptor stimulation on hepatosplanchnic oxygen kinetics and metabolic activity in septic shock. Crit Care Med. 1999 Feb;27(2):325-31.
16 Prediction and experimental validation of acute toxicity of beta-blockers in Ceriodaphnia dubia. Environ Toxicol Chem. 2005 Oct;24(10):2470-6.
17 Topical dorzolamide 2%/timolol 0.5% ophthalmic solution: a review of its use in the treatment of glaucoma and ocular hypertension. Drugs Aging. 2006;23(12):977-95.
18 Current therapeutic uses and potential of beta-adrenoceptor agonists and antagonists. Eur J Clin Pharmacol. 1998 Feb;53(6):389-404.
19 beta-adrenergic enhancement of brain kynurenic acid production mediated via cAMP-related protein kinase A signaling. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30;33(3):519-29.
20 beta(2)-adrenoceptors are critical for antidepressant treatment of neuropathic pain. Ann Neurol. 2009 Feb;65(2):218-25.
21 Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations. Am J Med Genet B Neuropsychiatr Genet. 2011 Sep;156B(6):651-60.
22 Different metabolism of norepinephrine and epinephrine by catechol-O-methyltransferase and monoamine oxidase in rats. J Pharmacol Exp Ther. 1994 Mar;268(3):1242-51.
23 Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition. Ther Drug Monit. 2004 Apr;26(2):137-44.
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