Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMNKG1Z)

Drug Name
Atenolol Drug Info
Synonyms
Aircrit; Alinor; Altol; Anselol; Antipressan; Atcardil; Atecard; Atehexal; Atenblock; Atendol; Atenet; Ateni; Atenil; Atenol; Atenolin; Atenololum; Atenomel; Atereal; Aterol; Betablok; Betacard; Betasyn; Blocotenol; Blokium; Cardaxen; Cardiopress; Corotenol; Cuxanorm; Duraatenolol; Duratenol; Evitocor; Farnormin; Hipres; Hypoten; Ibinolo; Internolol; Jenatenol; Juvental; Loten; Lotenal; Myocord; Neatenol; Normalol; Normiten; Noten; Oraday; Ormidol; Panapres; Plenacor; Premorine; Prenolol; Prenormine; Prinorm; Selobloc; Serten; Servitenol; Stermin; Tenidon; Tenobloc; Tenoblock; Tenolol; Tenoprin; Tenormin; Tenormine; Tensimin; Tensotin; Tredol; Unibloc; Uniloc; Vascoten; Vericordin; Wesipin; Xaten; Atenol AL; Atenol Atid; Atenol Cophar; Atenol Fecofar; Atenol GNR; Atenol Gador; Atenol Genericon; Atenol Heumann; Atenol MSD; Atenol NM Pharma; Atenol Nordic; Atenol PB; Atenol Quesada; Atenol Stada; Atenol Tika; Atenol Trom; Atenol acis; Atenol ct; Atenol von ct; Betatop Ge; Scheinpharm Atenol; Seles beta; Tenormine [French]; A 7655; Atenol 1A pharma; Apo-Atenolol; Atenol-Mepha; Atenol-Wolff; Atenol-ratiopharm; Atenololum [INN-Latin]; Felo-Bits; Lo-ten; Teno-basan; Tenormin (TN); Atenolol (JP15/USP/INN); Atenolol [USAN:INN:BAN:JAN]; Acetamide,2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl); (+-)-4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetamide; (+-)-Atenolol; (+/-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide; (1)-2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide; (inverted question mark)-Atenolol; 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol; 2-(4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl)acetamid; 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide; 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide; 2-[4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl]acetamide; 2-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide; 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide; 2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide; 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide; 4-[2'-Hydroxy-3'-(isopropylamino)propoxy]phenylacetamide; 4-[2-Hydroxy-3-(isopropylamino)-propoxy]phenylacetamide
Indication
Disease Entry ICD 11 Status REF
Angina pectoris BA40 Approved [1]
Hypertension BA00-BA04 Approved [2]
Malignant essential hypertension BA00 Approved [1]
Myocardial infarction BA41-BA43 Approved [1]
Therapeutic Class
Antihypertensive Agents
Cross-matching ID
PubChem CID
2249
ChEBI ID
CHEMBL24
CAS Number
CAS 29122-68-7
TTD Drug ID
DMNKG1Z
VARIDT Drug ID
DR00033
INTEDE Drug ID
DR0617
ACDINA Drug ID
D00048

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Adrenergic receptor beta-1 (ADRB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propranolol DM79NTF Angina pectoris BA40 Approved [18]
Epinephrine DM3KJBC Acute asthma CA23 Approved [19]
Norepinephrine DMOUC09 Alopecia ED70 Approved [20]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [3]
Metoprolol DMOJ0V6 Acute coronary syndrome BA41 Approved [3]
Timolol DM3NXRU High blood pressure BA00 Approved [21]
Isoproterenol DMK7MEY Atrioventricular block Approved [22]
Betaxolol DM6EUL5 Hypertension BA00-BA04 Approved [23]
Sotalol DML60TN Sinus rhythm disorder BC9Y Approved [24]
Nadolol DMW6GVL Angina pectoris BA40 Approved [25]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [26]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [28]
Folic Acid DMEMBJC Colorectal carcinoma Approved [29]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [28]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [28]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [30]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [28]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [31]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [32]
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Drug(s) Transported By Organic cation transporter 1 (SLC22A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [33]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [34]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [35]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [36]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [37]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [38]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [39]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [40]
Propranolol DM79NTF Angina pectoris BA40 Approved [41]
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Drug(s) Transported By Organic anion transporting polypeptide 1A2 (SLCO1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [42]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [43]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [44]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [45]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [46]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [47]
Saquinavir DMG814N Human immunodeficiency virus infection 1C62 Approved [48]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [49]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [50]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [51]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [52]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [53]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [54]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [55]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [56]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [57]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [58]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [59]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [53]
Verapamil DMA7PEW Angina pectoris BA40 Approved [60]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [61]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [62]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [63]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [56]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [60]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [64]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [65]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [66]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [67]
Propranolol DM79NTF Angina pectoris BA40 Approved [68]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [69]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [11]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [11]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [70]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [69]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [11]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [71]
Gefitinib DM15F0X Colon adenocarcinoma Approved [69]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [72]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [69]
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Drug(s) Affected By Renin (REN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [73]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [74]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [75]
Reboxetine DM26PRD Depression 6A70-6A7Z Approved [76]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [77]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [78]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [79]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [80]
Epinephrine DM3KJBC Acute asthma CA23 Approved [81]
Chlorthalidone DM4DMBT Edema MG29 Approved [82]
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Drug(s) Affected By Natriuretic peptides A (NPPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [83]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [84]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [86]
Cilazapril DM4V6JA Congestive heart failure BD10 Approved [87]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [88]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [89]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [90]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [92]
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Drug(s) Affected By Beta-2 adrenergic receptor (ADRB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salmeterol DMIEU69 Allergic asthma CA23.0 Approved [93]
Bambuterol DMKLSHF Asthma CA23 Approved [94]
Terbutaline DMD4381 Asthma CA23 Approved [95]
Salbutamol DMN9CWF Acute asthma CA23 Approved [96]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [97]
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Epinephrine DM3KJBC Acute asthma CA23 Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [101]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [102]
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Drug(s) Affected By Natriuretic peptides B (NPPB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [84]
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [103]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [105]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [108]
Ethanol DMDRQZU Chronic pain MG30 Approved [109]
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Drug(s) Affected By Reduced folate transporter (SLC19A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [110]
Methotrexate DM2TEOL Anterior urethra cancer Approved [111]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [112]
Selenium DM25CGV N. A. N. A. Approved [113]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ethanol DMDRQZU Chronic pain MG30 Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [114]
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Drug(s) Affected By Sodium- and chloride-dependent creatine transporter 1 (SLC6A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [112]
Selenium DM25CGV N. A. N. A. Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [115]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [116]
Panobinostat DM58WKG Chronic graft versus host disease Approved [117]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [118]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [119]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ampicillin DMHWE7P Acute epiglottitis Approved [115]
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Drug(s) Affected By Small nuclear ribonucleoprotein-associated protein N (SNRPN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Testosterone enanthate DMB6871 N. A. N. A. Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [122]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [123]
Folic Acid DMEMBJC Colorectal carcinoma Approved [124]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [114]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [125]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [126]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [127]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
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Drug(s) Affected By Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [130]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [131]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [132]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [133]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [119]
Testosterone enanthate DMB6871 N. A. N. A. Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [134]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [135]
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Drug(s) Affected By Solute carrier organic anion transporter family member 4C1 (SLCO4C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [115]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Panobinostat DM58WKG Chronic graft versus host disease Approved [117]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [119]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [134]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [123]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [138]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [139]
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Drug(s) Affected By C-type lectin domain family 2 member B (CLEC2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [140]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [141]
Testosterone enanthate DMB6871 N. A. N. A. Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [127]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [142]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [143]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [144]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [145]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [127]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [146]
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Drug(s) Affected By Ryanodine receptor 2 (RYR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [147]
Isoproterenol DMK7MEY Atrioventricular block Approved [148]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [149]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [150]
Metoprolol DMOJ0V6 Acute coronary syndrome BA41 Approved [147]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [149]
Arsenic DMTL2Y1 N. A. N. A. Approved [151]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [149]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [127]
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Drug(s) Affected By Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [152]
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [153]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Retigabine DMGNYIH Behcet disease 4A62 Approved [155]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [156]
Arsenic DMTL2Y1 N. A. N. A. Approved [151]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [126]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [157]
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Drug(s) Affected By Sodium channel protein type 5 subunit alpha (SCN5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [15]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [158]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [159]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [160]
Meloxicam DM2AR7L Arthritis FA20 Approved [161]
Quercetin DM3NC4M Obesity 5B81 Approved [162]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [153]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [163]
Retigabine DMGNYIH Behcet disease 4A62 Approved [155]
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Drug(s) Affected By Alpha-2A adrenergic receptor (ADRA2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [164]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [15]
Rilmenidine DM13PQW Hypertension BA00-BA04 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Indapamide DMGN1PW Edema MG29 Approved [168]
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Drug(s) Affected By Potassium voltage-gated channel subfamily E member 1 (KCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [134]
Pentobarbital DMFNH7L Brain ischaemia 8B1Z Approved [169]
Verapamil DMA7PEW Angina pectoris BA40 Approved [15]
Propranolol DM79NTF Angina pectoris BA40 Approved [15]
Diltiazem DMAI7ZV Angina pectoris BA40 Approved [15]
Sotalol DML60TN Sinus rhythm disorder BC9Y Approved [15]
Quinidine DMLPICK N. A. N. A. Approved [15]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [15]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [15]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor beta-1 (ADRB1) TTR6W5O ADRB1_HUMAN Antagonist [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [4]
Organic anion transporting polypeptide 1A2 (SLCO1A2) DTE2B1D SO1A2_HUMAN Substrate [5]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [7]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [8]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-2A adrenergic receptor (ADRA2A) OTZFGOTP ADA2A_HUMAN Drug Response [9]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Gene/Protein Processing [10]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [11]
C-type lectin domain family 2 member B (CLEC2B) OT0W0M0L CLC2B_HUMAN Gene/Protein Processing [12]
Natriuretic peptides A (NPPA) OTMQNTNX ANF_HUMAN Gene/Protein Processing [13]
Natriuretic peptides B (NPPB) OTSN2IPY ANFB_HUMAN Gene/Protein Processing [14]
Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5) OT404F9K FKBP5_HUMAN Gene/Protein Processing [12]
Potassium voltage-gated channel subfamily E member 1 (KCNE1) OTZNQUW9 KCNE1_HUMAN Drug Response [15]
Reduced folate transporter (SLC19A1) OTWB0BTO S19A1_HUMAN Gene/Protein Processing [16]
Renin (REN) OT52GZR2 RENI_HUMAN Gene/Protein Processing [17]

References

1 Atenolol FDA Label
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