Details of the Drug-Related molecule(s) Interaction Atlas

Chloroben Drug Info

Chloroden; Cloroben; Benzene, 1,2-dichloro-; Benzene, dichloro-; Benzene, o-dichloro-; Dichlorobenzene, o-; Dichlorobenzene, ortho, liquid; 2-Dichlorobenzene; Dilantin DB; Dilatin DB; Dizene; Dowtherm E; Orthodichlorobenzene; Orthodichlorobenzol; Special termite fluid; Termitkil; o-Dichlor benzol; o-Dichlorbenzene; o-Dichlorbenzol; o-Dichlorobenzene; o-Dichlorobenzol; ortho-Dichlorobenzene; 1,2-DICHLOROBENZENE; 1,2-Dichlorbenzene; 95-50-1; CCRIS 1360; Caswell No. 301; NCI-C54944; NSC 60644; ODCB; UNII-6PJ93I88XL; o-DCB

Cross-matching ID

PubChem CID

7239

ChEBI ID

CHEBI:35290

CAS Number

CAS 95-50-1

TTD Drug ID

DMY40UB

INTEDE Drug ID

DR0005

General Information of Drug (ID: DMY40UB)

Molecule-Related Drug Atlas

Molecule Type:

DME

DOT

Drug Status:

Approved Drug(s)

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Drug(s) Metabolized By Cytochrome P450 2E1 (CYP2E1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[4]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[5]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[6]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[7]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[8]
Oxaliplatin	DMQNWRD	Adenocarcinoma	2D40	Approved	[9]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[10]
Estrone	DM5T6US	Acne vulgaris	ED80	Approved	[11]
Propofol	DMB4OLE	Anaesthesia	9A78.6	Approved	[12]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[13]
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Drug(s) Affected By Glutathione S-transferase P (GSTP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Busulfan	DMXYJ9C	Chronic myelogenous leukaemia	2A20.0	Approved	[14]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[15]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[16]
Chlorambucil	DMRKE63	Chronic lymphocytic leukaemia	2A82.0	Approved	[16]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[17]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[18]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[19]
Selenium	DM25CGV	N. A.	N. A.	Approved	[20]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[21]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[22]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Amodiaquine	DME4RA8	Malaria	1F40-1F45	Approved	[23]
Riluzole	DMECBWN	Amyotrophic lateral sclerosis	8B60.0	Approved	[24]
Flutamide	DMK0O7U	Prostate cancer	2C82.0	Approved	[25]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[26]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[27]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[28]
Ethacrynic acid	DM60QMR	Edema	MG29	Approved	[29]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[30]
Ethinyl Estradiol	DMODJ40	Acne vulgaris	ED80	Approved	[31]
Clofibrate	DMPC1J7	Dysbetalipoproteinemia	5C80.2	Approved	[32]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zolmitriptan	DM1IB4Q	Migraine	8A80	Approved	[33]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[33]
Etoricoxib	DM6A4NW	Rheumatoid arthritis	FA20	Approved	[33]
Capsaicin	DMGMF6V	Back pain	ME84.Z	Approved	[34]
Hesperetin	DMKER83	High blood cholesterol level	5C80.00	Approved	[35]
Stiripentol	DMMSDOY	Dravet syndrome	8A61.11	Approved	[36]
Nifedipine	DMSVOZT	Angina pectoris	BA40	Approved	[37]
Zileuton	DMVRIC2	Allergic asthma	CA23.0	Approved	[38]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[39]
Clonidine	DM6RZ9Q	Attention deficit hyperactivity disorder	6A05.Z	Approved	[40]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 2E1 (CYP2E1)^{Main DME}	DEVDYN7	CP2E1_HUMAN	Substrate	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Biotransformations	[2]
Cytochrome P450 1A2 (CYP1A2)	OTLLBX48	CP1A2_HUMAN	Biotransformations	[2]
Glutathione S-transferase P (GSTP1)	OTLP0A0Y	GSTP1_HUMAN	Gene/Protein Processing	[3]

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References

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