Details of the Drug Combination

General Information of Drug Combination (ID: DC68MZD)

• Drug Combination Name: Etoposide + Cytarabine
• Indication: Adult Acute Basophilic Leukemia; Status: Phase 1 [1]
• Component Drugs:
  Etoposide (DMNH3PG): Small molecular drug
  Cytarabine (DMZD5QR): Small molecular drug

Molecular Interaction Atlas of This Drug Combination

Indication(s) of Etoposide

Disease Entry	ICD 11	Status	REF
Acute myelogenous leukaemia	2A41	Approved	[2]
Adult acute monocytic leukemia	N.A.	Approved	[2]
Adult kidney Wilms tumor	N.A.	Approved	[2]
Beckwith-Wiedemann syndrome	N.A.	Approved	[2]
Childhood kidney Wilms tumor	N.A.	Approved	[2]
Hamartoma	N.A.	Approved	[2]
Kidney neoplasm	N.A.	Approved	[2]
Lung cancer	2C25.0	Approved	[2]
Non-small-cell lung cancer	2C25.Y	Approved	[2]
Plasma cell myeloma	2A83.1	Approved	[2]
Small-cell lung cancer	2C25.Y	Approved	[2]
Solid tumour/cancer	2A00-2F9Z	Approved	[3]
Testicular cancer	2C80	Approved	[4]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[5]
Neuroblastoma	2D11.2	Investigative	[2]

Etoposide Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
DNA topoisomerase II (TOP2)	TT0IHXV	TOP2A_HUMAN; TOP2B_HUMAN	Modulator	[29]

Etoposide Interacts with 8 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
Multidrug resistance-associated protein 1 (ABCC1)	DTSYQGK	MRP1_HUMAN	Substrate	[30]
Multidrug resistance-associated protein 2 (ABCC2)	DTFI42L	MRP2_HUMAN	Substrate	[31]
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[32]
Breast cancer resistance protein (ABCG2)	DTI7UX6	ABCG2_HUMAN	Substrate	[33]
Organic anion transporting polypeptide 1B1 (SLCO1B1)	DT3D8F0	SO1B1_HUMAN	Substrate	[34]
Multidrug resistance-associated protein 3 (ABCC3)	DTQ3ZHF	MRP3_HUMAN	Substrate	[35]
Organic anion transporting polypeptide 1B3 (SLCO1B3)	DT9C1TS	SO1B3_HUMAN	Substrate	[36]
Organic anion transporting polypeptide 2B1 (SLCO2B1)	DTPFTEQ	SO2B1_HUMAN	Substrate	[34]

Etoposide Interacts with 9 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[37]
Cytochrome P450 1A2 (CYP1A2)	DEJGDUW	CP1A2_HUMAN	Metabolism	[37]
UDP-glucuronosyltransferase 1A1 (UGT1A1)	DEYGVN4	UD11_HUMAN	Metabolism	[8]
Cytochrome P450 3A5 (CYP3A5)	DEIBDNY	CP3A5_HUMAN	Metabolism	[38]
Cytochrome P450 2E1 (CYP2E1)	DEVDYN7	CP2E1_HUMAN	Metabolism	[39]
Glutathione S-transferase pi (GSTP1)	DEK6079	GSTP1_HUMAN	Metabolism	[40]
Prostaglandin G/H synthase 1 (COX-1)	DE073H6	PGH1_HUMAN	Metabolism	[41]
Glutathione S-transferase theta-1 (GSTT1)	DE3PKUG	GSTT1_HUMAN	Metabolism	[40]
Prostaglandin G/H synthase 2 (COX-2)	DE492CE	PGH2_HUMAN	Metabolism	[41]

Etoposide Interacts with 475 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Prostaglandin G/H synthase 2 (PTGS2)	OT75U9M4	PGH2_HUMAN	Increases Expression	[42]
Cytochrome P450 3A4 (CYP3A4)	OTQGYY83	CP3A4_HUMAN	Increases Expression	[43]
Cytochrome P450 1A2 (CYP1A2)	OTLLBX48	CP1A2_HUMAN	Increases Expression	[43]
Cytochrome P450 3A5 (CYP3A5)	OTSXFBXB	CP3A5_HUMAN	Decreases Methylation	[44]
Glutathione S-transferase P (GSTP1)	OTLP0A0Y	GSTP1_HUMAN	Decreases Response To Substance	[45]
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Increases Expression	[46]
ATP-binding cassette sub-family C member 3 (ABCC3)	OTC3IJV4	MRP3_HUMAN	Decreases Response To Substance	[47]
Multidrug resistance-associated protein 1 (ABCC1)	OTGUN89S	MRP1_HUMAN	Decreases Response To Substance	[45]
ATP-binding cassette sub-family C member 2 (ABCC2)	OTJSIGV5	MRP2_HUMAN	Affects Transport	[48]
DNA topoisomerase 2-alpha (TOP2A)	OT6LPS08	TOP2A_HUMAN	Decreases Response To Substance	[49]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Increases Phosphorylation	[50]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Increases Activity	[51]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Increases ADR	[52]
Caspase-8 (CASP8)	OTA8TVI8	CASP8_HUMAN	Decreases Response To Substance	[53]
Tumor protein p73 (TP73)	OT0LUO47	P73_HUMAN	Increases Expression	[9]
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1)	OTTK98BH	CP27B_HUMAN	Increases Expression	[9]
Dihydropyrimidinase-related protein 4 (DPYSL4)	OT3SBS2S	DPYL4_HUMAN	Increases Expression	[10]
Copper chaperone for superoxide dismutase (CCS)	OTXHT3QO	CCS_HUMAN	Increases Expression	[10]
Urokinase-type plasminogen activator (PLAU)	OTX0QGKK	UROK_HUMAN	Increases Expression	[10]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[10]
Ubiquitin-like protein ISG15 (ISG15)	OT53QQ7N	ISG15_HUMAN	Increases Expression	[10]
Integrin alpha-IIb (ITGA2B)	OT4Y17PY	ITA2B_HUMAN	Increases Expression	[10]
Ras-related protein R-Ras (RRAS)	OTBBF28C	RRAS_HUMAN	Increases Expression	[10]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[10]
Stomatin (STOM)	OTC8R6EH	STOM_HUMAN	Increases Expression	[10]
Cellular retinoic acid-binding protein 2 (CRABP2)	OTY01V9G	RABP2_HUMAN	Increases Expression	[10]
Tyrosine-protein kinase receptor UFO (AXL)	OTKA2SUX	UFO_HUMAN	Increases Expression	[10]
14-3-3 protein sigma (SFN)	OTLJCZ1U	1433S_HUMAN	Increases Expression	[10]
Galectin-7 (LGALS7)	OTMSVI7R	LEG7_HUMAN	Increases Expression	[10]
Rho GDP-dissociation inhibitor 2 (ARHGDIB)	OT9PD6CS	GDIR2_HUMAN	Increases Expression	[10]
Epithelial membrane protein 1 (EMP1)	OTSZHUHQ	EMP1_HUMAN	Increases Expression	[10]
Epithelial membrane protein 3 (EMP3)	OTODMJ1D	EMP3_HUMAN	Increases Expression	[10]
Protein ripply3 (RIPPLY3)	OT1HK35I	DSCR6_HUMAN	Increases Expression	[10]
Kinesin-like protein KIF1A (KIF1A)	OT3JVEGV	KIF1A_HUMAN	Increases Expression	[10]
Filamin-C (FLNC)	OT3F8J6Y	FLNC_HUMAN	Increases Expression	[10]
Immediate early response gene 5 protein (IER5)	OTJPTXMD	IER5_HUMAN	Increases Expression	[10]
Keratin, type II cytoskeletal 80 (KRT80)	OTAU54U3	K2C80_HUMAN	Increases Expression	[10]
All-trans-retinol 13,14-reductase (RETSAT)	OTC3AOPX	RETST_HUMAN	Increases Expression	[10]
Mitochondria-eating protein (SPATA18)	OTOEHTHU	MIEAP_HUMAN	Increases Expression	[10]
Tumor necrosis factor receptor superfamily member 14 (TNFRSF14)	OTB82PFO	TNR14_HUMAN	Increases Expression	[10]
Major histocompatibility complex class I-related gene protein (MR1)	OTZU3XX7	HMR1_HUMAN	Increases Expression	[10]
Roundabout homolog 3 (ROBO3)	OTPVG40S	ROBO3_HUMAN	Increases Expression	[10]
Neuronal PAS domain-containing protein 1 (NPAS1)	OTZKO6ZN	NPAS1_HUMAN	Increases Expression	[10]
Ankyrin repeat domain-containing protein 10 (ANKRD10)	OTIZ2VK8	ANR10_HUMAN	Decreases Expression	[10]
Serine/threonine-protein kinase PLK2 (PLK2)	OTKMJXJ8	PLK2_HUMAN	Increases Expression	[10]
Solute carrier family 2, facilitated glucose transporter member 6 (SLC2A6)	OTVUZCLG	GTR6_HUMAN	Increases Expression	[10]
Glutaminase liver isoform, mitochondrial (GLS2)	OT08MSHL	GLSL_HUMAN	Increases Expression	[10]
Endothelial protein C receptor (PROCR)	OTRHED17	EPCR_HUMAN	Increases Expression	[10]
Fatty acid desaturase 3 (FADS3)	OT9RVXGE	FADS3_HUMAN	Increases Expression	[10]
Catalase (CAT)	OTHEBX9R	CATA_HUMAN	Increases Activity	[54]
NADH-ubiquinone oxidoreductase chain 4 (ND4)	OT4RQVAA	NU4M_HUMAN	Increases Expression	[42]
Nitric oxide synthase, inducible (NOS2)	OTKKIOJ1	NOS2_HUMAN	Increases Expression	[42]
Transcription factor A, mitochondrial (TFAM)	OTXXV5V7	TFAM_HUMAN	Increases Expression	[42]
TP53-binding protein 1 (TP53BP1)	OTL8879S	TP53B_HUMAN	Increases Expression	[42]
Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B)	OTN6FKCB	PRGC2_HUMAN	Increases Expression	[42]
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)	OTHCDQ22	PRGC1_HUMAN	Increases Expression	[42]
Calsequestrin-2 (CASQ2)	OT09MNQ8	CASQ2_HUMAN	Decreases Expression	[11]
Telethonin (TCAP)	OTQQMJ94	TELT_HUMAN	Decreases Expression	[11]
LIM domain-binding protein 3 (LDB3)	OTGQL1AM	LDB3_HUMAN	Decreases Expression	[11]
Creatine kinase M-type (CKM)	OTME0KO7	KCRM_HUMAN	Decreases Expression	[11]
Glutathione peroxidase 1 (GPX1)	OTE2O72Q	GPX1_HUMAN	Increases Expression	[11]
Myosin light chain 3 (MYL3)	OTKD3RSX	MYL3_HUMAN	Decreases Expression	[11]
Keratin, type I cytoskeletal 19 (KRT19)	OTDGDQ75	K1C19_HUMAN	Increases Expression	[11]
Calmodulin-1 (CALM2)	OTNYA92F	CALM1_HUMAN	Increases Expression	[11]
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MYL2)	OT78PC0C	MLRV_HUMAN	Decreases Expression	[11]
Glycogen phosphorylase, muscle form (PYGM)	OTWLVWTV	PYGM_HUMAN	Decreases Expression	[11]
Dystrophin (DMD)	OTD21T5J	DMD_HUMAN	Decreases Expression	[11]
Myosin-7 (MYH7)	OT4Z9T8N	MYH7_HUMAN	Decreases Expression	[11]
Leukemia inhibitory factor (LIF)	OTO46S5S	LIF_HUMAN	Increases Expression	[11]
NAD(P)H dehydrogenase 1 (NQO1)	OTZGGIVK	NQO1_HUMAN	Increases Expression	[11]
Ankyrin-1 (ANK1)	OTU79URK	ANK1_HUMAN	Increases Expression	[11]
Desmin (DES)	OTI09KBW	DESM_HUMAN	Decreases Expression	[11]
Tumor necrosis factor receptor superfamily member 6 (FAS)	OTP9XG86	TNR6_HUMAN	Increases Expression	[11]
CCN family member 2 (CCN2)	OTC39NSU	CCN2_HUMAN	Increases Expression	[11]
Sodium/calcium exchanger 1 (SLC8A1)	OT787VRN	NAC1_HUMAN	Decreases Expression	[11]
Thrombospondin-4 (THBS4)	OTA1T9KK	TSP4_HUMAN	Increases Expression	[11]
Gap junction alpha-5 protein (GJA5)	OTRMZVO6	CXA5_HUMAN	Decreases Expression	[11]
Vasopressin V1a receptor (AVPR1A)	OTKR8AFL	V1AR_HUMAN	Increases Expression	[11]
Sodium/potassium-transporting ATPase subunit alpha-2 (ATP1A2)	OTCF8OWW	AT1A2_HUMAN	Decreases Expression	[11]
cAMP-dependent protein kinase catalytic subunit PRKX (PRKX)	OTDAC6Z0	PRKX_HUMAN	Increases Expression	[11]
Stanniocalcin-1 (STC1)	OTGVVXYF	STC1_HUMAN	Increases Expression	[11]
Myomesin-2 (MYOM2)	OTD2UOXW	MYOM2_HUMAN	Decreases Expression	[11]
Actin, alpha skeletal muscle (ACTA1)	OTOVGLPG	ACTS_HUMAN	Decreases Expression	[11]
Iroquois-class homeodomain protein IRX-4 (IRX4)	OT0TV6WK	IRX4_HUMAN	Decreases Expression	[11]
Arginase-2, mitochondrial (ARG2)	OTCPI0E8	ARGI2_HUMAN	Decreases Expression	[11]
Cytochrome c oxidase subunit 6A2, mitochondrial (COX6A2)	OTQR5SXD	CX6A2_HUMAN	Decreases Expression	[11]
Pro-neuregulin-1, membrane-bound isoform (NRG1)	OTZO6F1X	NRG1_HUMAN	Increases Expression	[11]
Dual specificity protein phosphatase 4 (DUSP4)	OT6WAO12	DUS4_HUMAN	Increases Expression	[11]
Krueppel-like factor 5 (KLF5)	OT1ABI9N	KLF5_HUMAN	Increases Expression	[11]
Four and a half LIM domains protein 2 (FHL2)	OT0OAYWT	FHL2_HUMAN	Decreases Expression	[11]
Transmembrane glycoprotein NMB (GPNMB)	OTB7KQKV	GPNMB_HUMAN	Increases Expression	[11]
Periostin (POSTN)	OTWP62UA	POSTN_HUMAN	Increases Expression	[11]
kinase isozyme 1, mitochondrial (PDK1)	OTMABK9Z	PDK1_HUMAN	Decreases Expression	[11]
kinase isozyme 4, mitochondrial (PDK4)	OTCMHMBZ	PDK4_HUMAN	Increases Expression	[11]
PDZ and LIM domain protein 3 (PDLIM3)	OTVXQC81	PDLI3_HUMAN	Increases Expression	[11]
Nebulin-related-anchoring protein (NRAP)	OTO6H3YF	NRAP_HUMAN	Decreases Expression	[11]
Sodium channel subunit beta-4 (SCN4B)	OT3JSUWO	SCN4B_HUMAN	Increases Expression	[11]
Actin-binding Rho-activating protein (ABRA)	OTBQ2C1J	ABRA_HUMAN	Increases Expression	[11]
Transient receptor potential cation channel subfamily V member 1 (TRPV1)	OTHHDR03	TRPV1_HUMAN	Increases Expression	[11]
Ryanodine receptor 2 (RYR2)	OT0PF19E	RYR2_HUMAN	Decreases Expression	[11]
Small conductance calcium-activated potassium channel protein 2 (KCNN2)	OTQVTMK5	KCNN2_HUMAN	Decreases Expression	[11]
Regulator of cell cycle RGCC (RGCC)	OTYJMLWM	RGCC_HUMAN	Increases Expression	[11]
Myotilin (MYOT)	OTCEW5XW	MYOTI_HUMAN	Increases Expression	[11]
Protein ATP1B4 (ATP1B4)	OT2YC9GZ	AT1B4_HUMAN	Increases Expression	[11]
Junctional adhesion molecule A (F11R)	OTGHPAV6	JAM1_HUMAN	Increases Expression	[11]
Succinate dehydrogenase assembly factor 1, mitochondrial (SDHAF1)	OTDG5VW7	SDHF1_HUMAN	Decreases Expression	[13]
Agrin (AGRN)	OTWJENAZ	AGRIN_HUMAN	Increases Expression	[12]
E3 ubiquitin-protein ligase TRIM38 (TRIM38)	OT6SP1M9	TRI38_HUMAN	Decreases Expression	[13]
Torsin-1A (TOR1A)	OTYCLGJU	TOR1A_HUMAN	Decreases Expression	[13]
Etoposide-induced protein 2.4 homolog (EI24)	OTD4NOYS	EI24_HUMAN	Increases Expression	[12]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)	OTA1CPBV	TR10B_HUMAN	Increases Expression	[55]
Tax1-binding protein 3 (TAX1BP3)	OTQ6IB4T	TX1B3_HUMAN	Increases Expression	[12]
Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB)	OT9RDS3H	IKKB_HUMAN	Decreases Expression	[56]
Proepiregulin (EREG)	OTRM4NQY	EREG_HUMAN	Increases Expression	[57]
Transcription factor EC (TFEC)	OTUST8MR	TFEC_HUMAN	Decreases Expression	[13]
Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK)	OTLF4ZB1	IKKA_HUMAN	Decreases Expression	[56]
Protein phosphatase 1D (PPM1D)	OT8NLZ9D	PPM1D_HUMAN	Increases Expression	[58]
Baculoviral IAP repeat-containing protein 5 (BIRC5)	OTILXZYL	BIRC5_HUMAN	Increases Expression	[59]
CASP8 and FADD-like apoptosis regulator (CFLAR)	OTX14BAS	CFLAR_HUMAN	Increases Expression	[60]
E3 ubiquitin-protein ligase RNF113A (RNF113A)	OTR6N7HU	R113A_HUMAN	Decreases Expression	[13]
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2)	OT0KMIYQ	RIPK2_HUMAN	Increases Expression	[59]
Krueppel-like factor 4 (KLF4)	OT4O9RQW	KLF4_HUMAN	Increases Expression	[61]
Forkhead box protein O3 (FOXO3)	OTHXQG4P	FOXO3_HUMAN	Increases Phosphorylation	[62]
Cytoplasmic protein NCK2 (NCK2)	OTUYPF55	NCK2_HUMAN	Decreases Expression	[12]
Protein regulator of cytokinesis 1 (PRC1)	OTHD0XS0	PRC1_HUMAN	Decreases Expression	[12]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)	OT80DZMT	BUB1_HUMAN	Decreases Expression	[63]
HMG box-containing protein 1 (HBP1)	OTDPGGDV	HBP1_HUMAN	Decreases Expression	[13]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)	OT8KME51	BUB1B_HUMAN	Decreases Expression	[63]
Cell division control protein 45 homolog (CDC45)	OT6NNLOD	CDC45_HUMAN	Decreases Expression	[63]
Nuclear receptor subfamily 1 group I member 2 (NR1I2)	OTC5U0N5	NR1I2_HUMAN	Increases Activity	[64]
Kinesin-like protein KIF20A (KIF20A)	OTXOQHE0	KI20A_HUMAN	Decreases Expression	[13]
Myelin protein zero-like protein 1 (MPZL1)	OTJSUUHR	MPZL1_HUMAN	Decreases Expression	[13]
Serine/threonine-protein kinase Chk2 (CHEK2)	OT8ZPCNS	CHK2_HUMAN	Increases Phosphorylation	[65]
Aldehyde dehydrogenase 1A1 (ALDH1A1)	OTCUWZKB	AL1A1_HUMAN	Increases Expression	[61]
Epidermal growth factor receptor (EGFR)	OTAPLO1S	EGFR_HUMAN	Decreases Expression	[57]
Protein c-Fos (FOS)	OTJBUVWS	FOS_HUMAN	Increases Expression	[66]
Protransforming growth factor alpha (TGFA)	OTPD1LL9	TGFA_HUMAN	Increases Expression	[57]
HLA class I histocompatibility antigen, B alpha chain (HLA-B)	OTNXFWY2	HLAB_HUMAN	Affects Expression	[67]
Transferrin receptor protein 1 (TFRC)	OT8ZPBDL	TFR1_HUMAN	Decreases Expression	[61]
Ferritin light chain (FTL)	OTYQA8A6	FRIL_HUMAN	Increases Expression	[61]
Metallothionein-2 (MT2A)	OTHOACHD	MT2_HUMAN	Decreases Expression	[16]
Interstitial collagenase (MMP1)	OTI4I2V1	MMP1_HUMAN	Decreases Expression	[68]
Superoxide dismutase , mitochondrial (SOD2)	OTIWXGZ9	SODM_HUMAN	Increases Expression	[51]
HLA class I histocompatibility antigen, A alpha chain (HLA-A)	OTAH14LU	HLAA_HUMAN	Affects Expression	[67]
Receptor tyrosine-protein kinase erbB-2 (ERBB2)	OTOAUNCK	ERBB2_HUMAN	Decreases Expression	[57]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Increases Acetylation	[69]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Increases Expression	[43]
Retinoblastoma-associated protein (RB1)	OTQJUJMZ	RB_HUMAN	Decreases Phosphorylation	[70]
Transcription factor Sp1 (SP1)	OTISPT4X	SP1_HUMAN	Increases Phosphorylation	[71]
High mobility group protein B1 (HMGB1)	OT4B7CPF	HMGB1_HUMAN	Increases Secretion	[72]
Annexin A4 (ANXA4)	OTUCRYXL	ANXA4_HUMAN	Increases Expression	[12]
Poly polymerase 1 (PARP1)	OT310QSG	PARP1_HUMAN	Increases Cleavage	[73]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Increases Expression	[74]
C-C motif chemokine 3 (CCL3)	OTW2H3ND	CCL3_HUMAN	Increases Expression	[74]
Androgen receptor (AR)	OTUBKAZZ	ANDR_HUMAN	Increases Degradation	[75]
Cholesteryl ester transfer protein (CETP)	OTAGPPOE	CETP_HUMAN	Increases Expression	[76]
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)	OTPWI88U	CEAM1_HUMAN	Increases Expression	[12]
Translationally-controlled tumor protein (TPT1)	OTHMTRJU	TCTP_HUMAN	Increases Expression	[77]
Tissue factor (F3)	OT3MSU3B	TF_HUMAN	Increases Expression	[78]
HLA class I histocompatibility antigen, alpha chain E (HLA-E)	OTX1CTFB	HLAE_HUMAN	Affects Expression	[67]
G2/mitotic-specific cyclin-B1 (CCNB1)	OT19S7E5	CCNB1_HUMAN	Decreases Expression	[63]
Protein C-ets-1 (ETS1)	OT4LVGDN	ETS1_HUMAN	Increases Expression	[56]
Amphiregulin (AREG)	OTJFOR67	AREG_HUMAN	Increases Expression	[57]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Expression	[79]
Syndecan-1 (SDC1)	OTWKRVZC	SDC1_HUMAN	Increases Expression	[12]
Cyclin-A2 (CCNA2)	OTPHHYZJ	CCNA2_HUMAN	Decreases Expression	[63]
Receptor tyrosine-protein kinase erbB-3 (ERBB3)	OTRSST0A	ERBB3_HUMAN	Decreases Expression	[57]
rRNA 2'-O-methyltransferase fibrillarin (FBL)	OTRODIE5	FBRL_HUMAN	Affects Localization	[80]
NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)	OTPDCK1F	ADRO_HUMAN	Increases Expression	[12]
Brain-derived neurotrophic factor (BDNF)	OTLGH7EW	BDNF_HUMAN	Increases Expression	[81]
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2)	OTIN6G20	CPT2_HUMAN	Decreases Expression	[13]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Increases Expression	[63]
Cyclin-dependent kinase 2 (CDK2)	OTB5DYYZ	CDK2_HUMAN	Increases Expression	[14]
NF-kappa-B inhibitor alpha (NFKBIA)	OTFT924M	IKBA_HUMAN	Increases Degradation	[82]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Increases Phosphorylation	[50]
Tripeptidyl-peptidase 2 (TPP2)	OT91OVAU	TPP2_HUMAN	Affects Localization	[83]
M-phase inducer phosphatase 1 (CDC25A)	OTSLKKCO	MPIP1_HUMAN	Decreases Expression	[13]
M-phase inducer phosphatase 3 (CDC25C)	OTPQI71S	MPIP3_HUMAN	Decreases Expression	[63]
Dual specificity protein kinase TTK (TTK)	OTBY1Z5H	TTK_HUMAN	Decreases Expression	[63]
DNA replication licensing factor MCM7 (MCM7)	OT6FXC6K	MCM7_HUMAN	Decreases Expression	[63]
Replication factor C subunit 1 (RFC1)	OT3L5PK3	RFC1_HUMAN	Decreases Expression	[13]
Tumor necrosis factor receptor superfamily member 3 (LTBR)	OT2HVZGV	TNR3_HUMAN	Increases Expression	[59]
Breast cancer type 1 susceptibility protein (BRCA1)	OT5BN6VH	BRCA1_HUMAN	Decreases Expression	[84]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[63]
Transcription factor ETV6 (ETV6)	OTCZMG61	ETV6_HUMAN	Increases Mutagenesis	[85]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9)	OTV9L89D	TNFL9_HUMAN	Increases Expression	[12]
Serine/threonine-protein kinase mTOR (MTOR)	OTHH8KU7	MTOR_HUMAN	Increases Phosphorylation	[86]
Caspase-2 (CASP2)	OTUDYSPP	CASP2_HUMAN	Increases Expression	[87]
RNA-binding protein 34 (RBM34)	OTX3LUGI	RBM34_HUMAN	Decreases Expression	[13]
DNA repair protein RAD52 homolog (RAD52)	OT0OTDHI	RAD52_HUMAN	Increases Expression	[88]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Increases Expression	[62]
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3)	OTI2OREX	MP2K3_HUMAN	Increases Expression	[12]
Tumor necrosis factor ligand superfamily member 6 (FASLG)	OTZARCHH	TNFL6_HUMAN	Increases Activity	[89]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Decreases Expression	[90]
Iron-responsive element-binding protein 2 (IREB2)	OT747D24	IREB2_HUMAN	Decreases Expression	[61]
Nuclear receptor-interacting protein 1 (NRIP1)	OTIZOJQV	NRIP1_HUMAN	Decreases Expression	[76]
Fatty acid synthase (FASN)	OTFII9KG	FAS_HUMAN	Increases Expression	[91]
Centromere protein F (CENPF)	OT7AG0SW	CENPF_HUMAN	Decreases Expression	[63]
CCAAT/enhancer-binding protein alpha (CEBPA)	OTOM9OE4	CEBPA_HUMAN	Decreases Expression	[92]
DNA replication licensing factor MCM2 (MCM2)	OTGGORIQ	MCM2_HUMAN	Decreases Expression	[63]
LIM/homeobox protein Lhx2 (LHX2)	OTK61NP8	LHX2_HUMAN	Decreases Expression	[13]
Serine/threonine-protein kinase Nek2 (NEK2)	OT1H27HO	NEK2_HUMAN	Decreases Expression	[63]
DNA mismatch repair protein Msh6 (MSH6)	OT46FP09	MSH6_HUMAN	Decreases Expression	[13]
Death-associated protein kinase 1 (DAPK1)	OTNCNUCO	DAPK1_HUMAN	Increases Expression	[56]
Mitogen-activated protein kinase 12 (MAPK12)	OTTCKE27	MK12_HUMAN	Increases Activity	[93]
RecQ-like DNA helicase BLM (BLM)	OTEJOAJX	BLM_HUMAN	Decreases Expression	[13]
Ataxin-1 (ATXN1)	OTQF0HNR	ATX1_HUMAN	Decreases Expression	[13]
Oxysterols receptor LXR-beta (NR1H2)	OT4APA60	NR1H2_HUMAN	Affects Localization	[76]
Caspase-7 (CASP7)	OTAPJ040	CASP7_HUMAN	Increases Activity	[94]
Caspase-9 (CASP9)	OTD4RFFG	CASP9_HUMAN	Increases Activity	[94]
BH3-interacting domain death agonist (BID)	OTOSHSHU	BID_HUMAN	Increases Expression	[59]
Triosephosphate isomerase (TPI1)	OT14KP4B	TPIS_HUMAN	Increases Phosphorylation	[95]
Small ribosomal subunit protein eS6 (RPS6)	OTT4D1LN	RS6_HUMAN	Increases Phosphorylation	[96]
DNA-dependent protein kinase catalytic subunit (PRKDC)	OTJVS4EG	PRKDC_HUMAN	Increases Phosphorylation	[71]
Protein BTG2 (BTG2)	OTZF6K1H	BTG2_HUMAN	Increases Expression	[13]
Hepcidin (HAMP)	OT607RBL	HEPC_HUMAN	Decreases Expression	[97]
Cytochrome c (CYCS)	OTBFALJD	CYC_HUMAN	Affects Localization	[51]
E3 ubiquitin-protein ligase Mdm2 (MDM2)	OTOVXARF	MDM2_HUMAN	Increases Expression	[63]
Runt-related transcription factor 1 (RUNX1)	OTU7J84H	RUNX1_HUMAN	Increases Mutagenesis	[85]
Myelin transcription factor 1 (MYT1)	OTC3660I	MYT1_HUMAN	Decreases Expression	[63]
POU domain, class 5, transcription factor 1 (POU5F1)	OTDHHN7O	PO5F1_HUMAN	Increases Expression	[61]
DNA topoisomerase 2-beta (TOP2B)	OTDHKQZ8	TOP2B_HUMAN	Decreases Activity	[98]
Histone-lysine N-methyltransferase 2A (KMT2A)	OT9GLJI6	KMT2A_HUMAN	Increases Cleavage	[99]
Antigen peptide transporter 1 (TAP1)	OTJL27PW	TAP1_HUMAN	Increases Expression	[12]
CCAAT/enhancer-binding protein zeta (CEBPZ)	OT11BATG	CEBPZ_HUMAN	Decreases Expression	[12]
Apoptosis regulator BAX (BAX)	OTAW0V4V	BAX_HUMAN	Increases Expression	[63]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)	OT2YYI1A	MCL1_HUMAN	Decreases Expression	[62]
Forkhead box protein O1 (FOXO1)	OTPJRB6D	FOXO1_HUMAN	Increases Phosphorylation	[62]
Chromatin assembly factor 1 subunit A (CHAF1A)	OTXSSY4H	CAF1A_HUMAN	Decreases Expression	[13]
Oxysterols receptor LXR-alpha (NR1H3)	OT54YZ9I	NR1H3_HUMAN	Increases Expression	[76]
Serine-protein kinase ATM (ATM)	OTQVOHLT	ATM_HUMAN	Increases Phosphorylation	[100]
DNA topoisomerase 3-alpha (TOP3A)	OT3CKUI9	TOP3A_HUMAN	Decreases Expression	[13]
Baculoviral IAP repeat-containing protein 3 (BIRC3)	OT3E95KB	BIRC3_HUMAN	Decreases Expression	[63]
Baculoviral IAP repeat-containing protein 2 (BIRC2)	OTFXFREP	BIRC2_HUMAN	Increases Expression	[101]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)	OTXEE550	APR_HUMAN	Increases Expression	[53]
Protein BTG3 (BTG3)	OT9ANHVT	BTG3_HUMAN	Decreases Expression	[13]
Histone RNA hairpin-binding protein (SLBP)	OTVYYQRT	SLBP_HUMAN	Decreases Expression	[13]
Hypermethylated in cancer 1 protein (HIC1)	OTI9TWY4	HIC1_HUMAN	Increases Expression	[102]
DNA replication licensing factor MCM6 (MCM6)	OTKLIAWT	MCM6_HUMAN	Decreases Expression	[63]
Receptor tyrosine-protein kinase erbB-4 (ERBB4)	OT9L6C41	ERBB4_HUMAN	Decreases Expression	[57]
Neutral amino acid transporter B(0) (SLC1A5)	OTE2H26Q	AAAT_HUMAN	Decreases Expression	[13]
Mothers against decapentaplegic homolog 2 (SMAD2)	OTC6VB4K	SMAD2_HUMAN	Increases Phosphorylation	[90]
Cyclin-G2 (CCNG2)	OTII38K2	CCNG2_HUMAN	Increases Expression	[103]
Cyclin-dependent kinase inhibitor 3 (CDKN3)	OTBE3H07	CDKN3_HUMAN	Decreases Expression	[63]
Quinone oxidoreductase PIG3 (TP53I3)	OTSCM68G	QORX_HUMAN	Increases Expression	[12]
Ribosomal protein eS27-like (RPS27L)	OTZWHU0N	RS27L_HUMAN	Increases Expression	[104]
Protein MCM10 homolog (MCM10)	OTV0O3JN	MCM10_HUMAN	Decreases Expression	[13]
EPM2A-interacting protein 1 (EPM2AIP1)	OT21ALNF	EPMIP_HUMAN	Increases Expression	[12]
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B)	OTE8GBUR	RIR2B_HUMAN	Increases Expression	[105]
Partner and localizer of BRCA2 (PALB2)	OT6DNDBG	PALB2_HUMAN	Decreases Expression	[13]
Jouberin (AHI1)	OT8K2YWY	AHI1_HUMAN	Increases Expression	[106]
Leucine-rich repeat-containing protein 47 (LRRC47)	OTSE8NAO	LRC47_HUMAN	Decreases Expression	[13]
RelA-associated inhibitor (PPP1R13L)	OTNCPLWE	IASPP_HUMAN	Increases Expression	[107]
DNA repair and recombination protein RAD54-like (RAD54L)	OTEGMAKG	RAD54_HUMAN	Increases Expression	[14]
Cytochrome c oxidase assembly factor 7 (COA7)	OTRQJYL6	COA7_HUMAN	Decreases Expression	[13]
Mitochondrial potassium channel (CCDC51)	OTOJNHNA	MITOK_HUMAN	Decreases Expression	[13]
Integrator complex subunit 15 (INTS15)	OT3O4INM	INT15_HUMAN	Decreases Expression	[13]
Bcl-2-binding component 3, isoforms 3/4 (BBC3)	OTUAXDAY	BBC3B_HUMAN	Increases Expression	[53]
Proheparin-binding EGF-like growth factor (HBEGF)	OTLU00JS	HBEGF_HUMAN	Increases Expression	[57]
Krueppel-like factor 6 (KLF6)	OTQY9S7F	KLF6_HUMAN	Decreases Expression	[13]
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)	OTQR6ENW	M3K5_HUMAN	Decreases Expression	[12]
Cell division control protein 6 homolog (CDC6)	OTX93FE7	CDC6_HUMAN	Decreases Expression	[63]
Growth/differentiation factor 15 (GDF15)	OTWQN50N	GDF15_HUMAN	Increases Expression	[63]
SOSS complex subunit B1 (NABP2)	OTQU8081	SOSB1_HUMAN	Increases Acetylation	[108]
Protein pelota homolog (PELO)	OTF3WLIM	PELO_HUMAN	Decreases Expression	[13]
TIMELESS-interacting protein (TIPIN)	OT9PZHXV	TIPIN_HUMAN	Decreases Expression	[13]
Cell cycle regulator of non-homologous end joining (CYREN)	OT5ZL00R	CYREN_HUMAN	Affects Localization	[109]
Caspase recruitment domain-containing protein 10 (CARD10)	OT2RPM4I	CAR10_HUMAN	Increases Expression	[59]
Angiotensin-converting enzyme 2 (ACE2)	OTTRZGU7	ACE2_HUMAN	Decreases Expression	[110]
Sulfiredoxin-1 (SRXN1)	OTYDBO4L	SRXN1_HUMAN	Increases Expression	[111]
tRNA pseudouridine(38/39) synthase (PUS3)	OT6WG6M2	PUS3_HUMAN	Decreases Expression	[13]
Homeodomain-interacting protein kinase 2 (HIPK2)	OTDB7QC3	HIPK2_HUMAN	Increases Activity	[81]
Serine/threonine-protein kinase PLK3 (PLK3)	OT19CT2Z	PLK3_HUMAN	Increases Expression	[12]
Transmembrane protein 185B (TMEM185B)	OTGNYS0J	T185B_HUMAN	Decreases Expression	[13]
Interferon-stimulated 20 kDa exonuclease-like 2 (ISG20L2)	OT3Q11WQ	I20L2_HUMAN	Decreases Expression	[13]
GrpE protein homolog 1, mitochondrial (GRPEL1)	OT8O00YJ	GRPE1_HUMAN	Decreases Expression	[13]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)	OT5V52LN	TNR12_HUMAN	Increases Expression	[59]
Programmed cell death 1 ligand 1 (CD274)	OTJ0VFDL	PD1L1_HUMAN	Increases Expression	[112]
Forkhead box protein J2 (FOXJ2)	OTPT639J	FOXJ2_HUMAN	Decreases Expression	[13]
rRNA methyltransferase 2, mitochondrial (MRM2)	OTRYA1HU	MRM2_HUMAN	Decreases Expression	[13]
DNA helicase MCM8 (MCM8)	OTC93H3S	MCM8_HUMAN	Decreases Expression	[63]
Frizzled-1 (FZD1)	OTZATHVS	FZD1_HUMAN	Decreases Expression	[13]
Calcium-binding protein 39 (CAB39)	OT2CL9ST	CAB39_HUMAN	Decreases Expression	[12]
5'-AMP-activated protein kinase subunit beta-1 (PRKAB1)	OT1OG4QZ	AAKB1_HUMAN	Increases Expression	[13]
Sestrin-1 (SESN1)	OTSFDZWL	SESN1_HUMAN	Increases Expression	[13]
Nuclear factor erythroid 2-related factor 2 (NFE2L2)	OT0HENJ5	NF2L2_HUMAN	Decreases Response To Substance	[113]
Molybdenum cofactor sulfurase (MOCOS)	OT0TL3Q5	MOCOS_HUMAN	Affects Response To Substance	[18]
Tripartite motif-containing protein 2 (TRIM2)	OT0V1YVC	TRIM2_HUMAN	Affects Response To Substance	[18]
V-type proton ATPase 116 kDa subunit a 4 (ATP6V0A4)	OT149Z7Q	VPP4_HUMAN	Affects Response To Substance	[18]
Insulin-like growth factor-binding protein 7 (IGFBP7)	OT1D416P	IBP7_HUMAN	Affects Response To Substance	[18]
Acid ceramidase (ASAH1)	OT1DNGXL	ASAH1_HUMAN	Affects Response To Substance	[18]
D-3-phosphoglycerate dehydrogenase (PHGDH)	OT1LMRTG	SERA_HUMAN	Affects Response To Substance	[18]
Calcipressin-1 (RCAN1)	OT1MVXC7	RCAN1_HUMAN	Affects Response To Substance	[18]
Melanoma antigen recognized by T-cells 1 (MLANA)	OT1N2S2K	MAR1_HUMAN	Affects Response To Substance	[18]
Serine palmitoyltransferase small subunit A (SPTSSA)	OT2PNKOP	SPTSA_HUMAN	Affects Response To Substance	[18]
Large neutral amino acids transporter small subunit 1 (SLC7A5)	OT2WPVXD	LAT1_HUMAN	Affects Response To Substance	[18]
Chitinase-3-like protein 1 (CHI3L1)	OT2Z7VJH	CH3L1_HUMAN	Decreases Response To Substance	[114]
Syncytin-2 (ERVFRD-1)	OT3064D7	SYCY2_HUMAN	Affects Response To Substance	[18]
DNA-directed RNA polymerase I subunit RPA12 (POLR1H)	OT30S3SB	RPA12_HUMAN	Decreases Response To Substance	[115]
Protein FAM171A1 (FAM171A1)	OT33BHEP	F1711_HUMAN	Affects Response To Substance	[18]
Fatty acid CoA ligase Acsl3 (ACSL3)	OT3MWER1	ACSL3_HUMAN	Affects Response To Substance	[18]
Platelet-derived growth factor C (PDGFC)	OT3ZJ0XU	PDGFC_HUMAN	Affects Response To Substance	[18]
Insulin receptor substrate 2 (IRS2)	OT46MJBE	IRS2_HUMAN	Affects Response To Substance	[18]
Nuclear protein 1 (NUPR1)	OT4FU8C0	NUPR1_HUMAN	Affects Response To Substance	[18]
Proteinase-activated receptor 1 (F2R)	OT4WVWBO	PAR1_HUMAN	Affects Response To Substance	[18]
Roundabout homolog 1 (ROBO1)	OT52UFVS	ROBO1_HUMAN	Affects Response To Substance	[18]
DNA repair nuclease/redox regulator APEX1 (APEX1)	OT53OI14	APEX1_HUMAN	Decreases Response To Substance	[116]
Lymphokine-activated killer T-cell-originated protein kinase (PBK)	OT5Z27TW	TOPK_HUMAN	Affects Response To Substance	[18]
Protein E7 (E7)	OT6BIMFN	VE7_HPV16	Increases ADR	[52]
G-protein-signaling modulator 2 (GPSM2)	OT6RPMRM	GPSM2_HUMAN	Affects Response To Substance	[18]
CD40 ligand (CD40LG)	OT75Z6A6	CD40L_HUMAN	Decreases Response To Substance	[117]
Monocarboxylate transporter 7 (SLC16A6)	OT7BIIZX	MOT7_HUMAN	Affects Response To Substance	[18]
Homeobox protein engrailed-2 (EN2)	OT7EZCM2	HME2_HUMAN	Affects Response To Substance	[18]
Ras-related protein Rab-17 (RAB17)	OT7NBUGQ	RAB17_HUMAN	Affects Response To Substance	[18]
Fibroblast growth factor 2 (FGF2)	OT7YUJ9F	FGF2_HUMAN	Affects Response To Substance	[18]
Myelin proteolipid protein (PLP1)	OT8CM9CX	MYPR_HUMAN	Affects Response To Substance	[18]
RAC-alpha serine/threonine-protein kinase (AKT1)	OT8H2YY7	AKT1_HUMAN	Increases Response To Substance	[118]
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1B)	OT8JQ1F7	PI51B_HUMAN	Affects Response To Substance	[18]
Neuronal membrane glycoprotein M6-b (GPM6B)	OT8Q1582	GPM6B_HUMAN	Affects Response To Substance	[18]
Melanoma-associated antigen 12 (MAGEA12)	OT8ULELL	MAGAC_HUMAN	Affects Response To Substance	[18]
Solute carrier family 22 member 18 (SLC22A18)	OT9C3KR4	S22AI_HUMAN	Affects Response To Substance	[18]
Thymosin beta-4 (TMSB4X)	OT9HPLP3	TYB4_HUMAN	Decreases Response To Substance	[119]
Follicle-stimulating hormone receptor (FSHR)	OT9MVMLI	FSHR_HUMAN	Increases ADR	[120]
Oxidoreductase HTATIP2 (HTATIP2)	OT9MZ4QO	HTAI2_HUMAN	Affects Response To Substance	[18]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2)	OT9PBQVT	SIA7B_HUMAN	Affects Response To Substance	[18]
Splicing factor 45 (RBM17)	OT9ROJCL	SPF45_HUMAN	Decreases Response To Substance	[121]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Affects Response To Substance	[122]
Retinoblastoma tumor suppressor (RB1)	OT9VMY7B	Q5J3Q9_FUNHE	Increases ADR	[52]
Tissue factor pathway inhibitor (TFPI)	OTA0FX16	TFPI1_HUMAN	Affects Response To Substance	[18]
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM)	OTA4P0FC	ACADM_HUMAN	Affects Response To Substance	[18]
POM121 and ZP3 fusion protein (POMZP3)	OTAH2JOK	POZP3_HUMAN	Affects Response To Substance	[18]
Transmembrane protein 47 (TMEM47)	OTAJ4CPX	TMM47_HUMAN	Affects Response To Substance	[18]
Glutathione S-transferase theta-2 (GSTT2)	OTANW3TJ	GST2_HUMAN	Affects Response To Substance	[18]
Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1)	OTAYZZE6	AL3A1_HUMAN	Affects Response To Substance	[123]
5-hydroxytryptamine receptor 4 (HTR4)	OTBIB44K	5HT4R_HUMAN	Affects Response To Substance	[18]
High mobility group protein HMGI-C (HMGA2)	OTBMBHHL	HMGA2_HUMAN	Affects Response To Substance	[18]
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1)	OTBML9D9	CGAT1_HUMAN	Affects Response To Substance	[18]
Microtubule-associated tumor suppressor 1 (MTUS1)	OTBPALMU	MTUS1_HUMAN	Affects Response To Substance	[18]
Cystathionine gamma-lyase (CTH)	OTC90LA0	CGL_HUMAN	Affects Response To Substance	[18]
Melanocyte protein PMEL (PMEL)	OTCDDHHM	PMEL_HUMAN	Affects Response To Substance	[18]
BMP and activin membrane-bound inhibitor homolog (BAMBI)	OTCEJ8W5	BAMBI_HUMAN	Affects Response To Substance	[18]
Alkaline phosphatase, germ cell type (ALPG)	OTCIM29R	PPBN_HUMAN	Affects Response To Substance	[18]
Creatine kinase U-type, mitochondrial (CKMT1A)	OTCINHH5	KCRU_HUMAN	Affects Response To Substance	[18]
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1)	OTCJ458Q	AT1A1_HUMAN	Affects Response To Substance	[18]
Ras-interacting protein 1 (RASIP1)	OTCRY2AN	RAIN_HUMAN	Affects Response To Substance	[18]
Collagen alpha-3(IX) chain (COL9A3)	OTCUJOEK	CO9A3_HUMAN	Affects Response To Substance	[18]
A-kinase anchor protein 12 (AKAP12)	OTCVRDDX	AKA12_HUMAN	Affects Response To Substance	[18]
Interferon-stimulated gene 20 kDa protein (ISG20)	OTCWRJJW	ISG20_HUMAN	Affects Response To Substance	[18]
Stathmin (STMN1)	OTDJ4RV0	STMN1_HUMAN	Affects Response To Substance	[124]
Bcl-2 homologous antagonist/killer (BAK1)	OTDP6ILW	BAK_HUMAN	Increases Response To Substance	[125]
Dickkopf-related protein 3 (DKK3)	OTDU94EY	DKK3_HUMAN	Affects Response To Substance	[18]
P protein (OCA2)	OTDWIGBF	P_HUMAN	Affects Response To Substance	[18]
Cystatin-SN (CST1)	OTE4I83Q	CYTN_HUMAN	Affects Response To Substance	[18]
Alternative prion protein (PRNP)	OTE85L1Q	APRIO_HUMAN	Decreases Response To Substance	[126]
Fructose-bisphosphate aldolase C (ALDOC)	OTEC13I5	ALDOC_HUMAN	Affects Response To Substance	[18]
Interferon-induced transmembrane protein 1 (IFITM1)	OTECO1G8	IFM1_HUMAN	Affects Response To Substance	[18]
Epidermal growth factor-like protein 8 (EGFL8)	OTECTJ7K	EGFL8_HUMAN	Affects Response To Substance	[18]
dTDP-D-glucose 4,6-dehydratase (TGDS)	OTEOFLOS	TGDS_HUMAN	Affects Response To Substance	[18]
Mitogen-activated protein kinase 8 (MAPK8)	OTEREYS5	MK08_HUMAN	Increases ADR	[52]
Ras association domain-containing protein 1 (RASSF1)	OTEZIPB7	RASF1_HUMAN	Increases Response To Substance	[127]
Transcription factor SOX-10 (SOX10)	OTF25ULQ	SOX10_HUMAN	Affects Response To Substance	[18]
Eukaryotic translation initiation factor 3 subunit A (EIF3A)	OTFABY9G	EIF3A_HUMAN	Increases Response To Substance	[128]
Sortilin (SORT1)	OTFCQ4B1	SORT_HUMAN	Affects Response To Substance	[18]
Kelch-like ECH-associated protein 1 (KEAP1)	OTFHOD0C	KEAP1_HUMAN	Increases Response To Substance	[113]
Myelin basic protein (MBP)	OTFZCEDB	MBP_HUMAN	Affects Response To Substance	[18]
Protein AF1q (MLLT11)	OTG5RVHC	AF1Q_HUMAN	Affects Response To Substance	[18]
Tudor domain-containing protein 3 (TDRD3)	OTG83E2C	TDRD3_HUMAN	Affects Response To Substance	[18]
Enhancer of filamentation 1 (NEDD9)	OTGCFN4M	CASL_HUMAN	Affects Response To Substance	[18]
Squalene synthase (FDFT1)	OTGDISIT	FDFT_HUMAN	Affects Response To Substance	[18]
Voltage-gated potassium channel subunit beta-2 (KCNAB2)	OTH115IE	KCAB2_HUMAN	Affects Response To Substance	[18]
Dual specificity protein phosphatase 2 (DUSP2)	OTH54FMR	DUS2_HUMAN	Affects Response To Substance	[18]
Sigma intracellular receptor 2 (TMEM97)	OTH76ZWK	SGMR2_HUMAN	Affects Response To Substance	[18]
Melanoma-associated antigen C1 (MAGEC1)	OTHMFHH8	MAGC1_HUMAN	Affects Response To Substance	[18]
Tribbles homolog 2 (TRIB2)	OTHSX3MX	TRIB2_HUMAN	Affects Response To Substance	[18]
DNA damage-inducible transcript 4 protein (DDIT4)	OTHY8SY4	DDIT4_HUMAN	Affects Response To Substance	[18]
BAG family molecular chaperone regulator 2 (BAG2)	OTI6LD27	BAG2_HUMAN	Affects Response To Substance	[18]
Nucleosome assembly protein 1-like 1 (NAP1L1)	OTI7WBZV	NP1L1_HUMAN	Affects Response To Substance	[18]
Melanoma-associated antigen 6 (MAGEA6)	OTI8S0O2	MAGA6_HUMAN	Affects Response To Substance	[18]
Prosaposin receptor GPR37 (GPR37)	OTIMDDI3	GPR37_HUMAN	Affects Response To Substance	[18]
Kynureninase (KYNU)	OTINL2RE	KYNU_HUMAN	Affects Response To Substance	[18]
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA)	OTIOLNHE	LICH_HUMAN	Affects Response To Substance	[18]
Baculoviral IAP repeat-containing protein 7 (BIRC7)	OTITCGHB	BIRC7_HUMAN	Decreases Response To Substance	[129]
Runt-related transcription factor 3 (RUNX3)	OTITK1XD	RUNX3_HUMAN	Increases Response To Substance	[130]
Protein S100-P (S100P)	OTJCXNJG	S100P_HUMAN	Increases Response To Substance	[131]
Osteopontin (SPP1)	OTJGC23Y	OSTP_HUMAN	Affects Response To Substance	[18]
cAMP-responsive element modulator (CREM)	OTJIJ5AL	CREM_HUMAN	Affects Response To Substance	[18]
Alpha-(1,6)-fucosyltransferase (FUT8)	OTJJCVG1	FUT8_HUMAN	Affects Response To Substance	[18]
Trefoil factor 3 (TFF3)	OTJJDRTU	TFF3_HUMAN	Affects Response To Substance	[18]
Transcription factor-like 5 protein (TCFL5)	OTJL4348	TCFL5_HUMAN	Affects Response To Substance	[18]
Uncharacterized protein C4orf19 (C4ORF19)	OTJMU7N6	CD019_HUMAN	Affects Response To Substance	[18]
Sorbin and SH3 domain-containing protein 2 (SORBS2)	OTJSX44Y	SRBS2_HUMAN	Affects Response To Substance	[18]
Myc box-dependent-interacting protein 1 (BIN1)	OTK8O0X8	BIN1_HUMAN	Increases Response To Substance	[132]
Transmembrane channel-like protein 6 (TMC6)	OTKH50J4	TMC6_HUMAN	Affects Response To Substance	[18]
Cystine/glutamate transporter (SLC7A11)	OTKJ6PXW	XCT_HUMAN	Affects Response To Substance	[133]
B-cell receptor-associated protein 31 (BCAP31)	OTKSACR4	BAP31_HUMAN	Increases ADR	[52]
Myelin P2 protein (PMP2)	OTKYV2NE	MYP2_HUMAN	Affects Response To Substance	[18]
Cytochrome P450 26A1 (CYP26A1)	OTL1DFWV	CP26A_HUMAN	Decreases Response To Substance	[134]
Histone-binding protein RBBP7 (RBBP7)	OTLB56HX	RBBP7_HUMAN	Increases ADR	[52]
Glycylpeptide N-tetradecanoyltransferase 2 (NMT2)	OTLNA39Z	NMT2_HUMAN	Affects Response To Substance	[18]
Tyrosine-protein kinase Fyn (FYN)	OTLSLVZS	FYN_HUMAN	Affects Response To Substance	[18]
Homeobox protein Hox-A5 (HOXA5)	OTLWGPQD	HXA5_HUMAN	Affects Response To Substance	[18]
DNA cytosine-5)-methyltransferase 1 (DNMT1)	OTM2DGTK	DNMT1_HUMAN	Decreases Response To Substance	[135]
Lymphocyte antigen 6E (LY6E)	OTMG16BZ	LY6E_HUMAN	Affects Response To Substance	[18]
Bridging integrator 3 (BIN3)	OTMIWWDW	BIN3_HUMAN	Affects Response To Substance	[18]
Bcl-2-like protein 2 (BCL2L2)	OTMKVO0J	B2CL2_HUMAN	Decreases Response To Substance	[136]
Histone-lysine N-methyltransferase 2B (KMT2B)	OTMMAZQX	KMT2B_HUMAN	Increases ADR	[52]
Copper-transporting ATPase 1 (ATP7A)	OTMR3GXP	ATP7A_HUMAN	Decreases Response To Substance	[137]
Transcription factor AP-2-alpha (TFAP2A)	OTMYT3NK	AP2A_HUMAN	Increases Response To Substance	[138]
Protein kinase C zeta type (PRKCZ)	OTN2FE42	KPCZ_HUMAN	Increases Response To Substance	[139]
Four and a half LIM domains protein 1 (FHL1)	OTN535SU	FHL1_HUMAN	Affects Response To Substance	[18]
Epithelial splicing regulatory protein 1 (ESRP1)	OTNCS4SL	ESRP1_HUMAN	Affects Response To Substance	[18]
Beta-secretase 2 (BACE2)	OTO5YQVK	BACE2_HUMAN	Affects Response To Substance	[18]
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B)	OTOA8WU2	PDE4B_HUMAN	Affects Response To Substance	[18]
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1)	OTOEEEXG	HPRT_HUMAN	Increases ADR	[52]
Myeloperoxidase (MPO)	OTOOXLIN	PERM_HUMAN	Increases Metabolism	[140]
Glutathione S-transferase Mu 4 (GSTM4)	OTOTF8DU	GSTM4_HUMAN	Affects Response To Substance	[18]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)	OTOWDUNT	PTEN_HUMAN	Increases Response To Substance	[62]
Interleukin-4 (IL4)	OTOXBWAU	IL4_HUMAN	Decreases Response To Substance	[27]
Ras-related protein Rab-20 (RAB20)	OTP9OOVS	RAB20_HUMAN	Affects Response To Substance	[18]
DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C)	OTPL0AI1	ABC3C_HUMAN	Affects Response To Substance	[18]
Epithelial membrane protein 2 (EMP2)	OTPS2H0L	EMP2_HUMAN	Affects Response To Substance	[18]
Ropporin-1A (ROPN1)	OTPXKZTX	ROP1A_HUMAN	Affects Response To Substance	[18]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP)	OTPYQX3K	C1QBP_HUMAN	Decreases Response To Substance	[141]
Cyclic GMP-AMP phosphodiesterase SMPDL3A (SMPDL3A)	OTQDYH8E	ASM3A_HUMAN	Affects Response To Substance	[18]
Histone deacetylase 4 (HDAC4)	OTQNGD32	HDAC4_HUMAN	Affects Response To Substance	[18]
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (ANKRD28)	OTRBREQ9	ANR28_HUMAN	Affects Response To Substance	[18]
Bcl-2-like protein 1 (BCL2L1)	OTRC5K9O	B2CL1_HUMAN	Decreases Response To Substance	[142]
Disabled homolog 2 (DAB2)	OTRMQTMZ	DAB2_HUMAN	Affects Response To Substance	[18]
Large ribosomal subunit protein eL6 (RPL6)	OTRU71O4	RL6_HUMAN	Decreases Response To Substance	[143]
Band 4.1-like protein 3 (EPB41L3)	OTS6CHG2	E41L3_HUMAN	Affects Response To Substance	[18]
Glutathione S-transferase Mu 1 (GSTM1)	OTSBF2MO	GSTM1_HUMAN	Affects Response To Substance	[28]
Heat shock-related 70 kDa protein 2 (HSPA2)	OTSDET7B	HSP72_HUMAN	Affects Response To Substance	[18]
MyoD family inhibitor domain-containing protein (MDFIC)	OTSRYBWZ	MDFIC_HUMAN	Affects Response To Substance	[18]
Terminal nucleotidyltransferase 5A (TENT5A)	OTSYF511	TET5A_HUMAN	Affects Response To Substance	[18]
Collagen alpha-1(XV) chain (COL15A1)	OTTFKK18	COFA1_HUMAN	Affects Response To Substance	[18]
Bcl-2-interacting killer (BIK)	OTTH1T3D	BIK_HUMAN	Increases Response To Substance	[144]
Serine/threonine-protein kinase Chk1 (CHEK1)	OTTTI622	CHK1_HUMAN	Affects Response To Substance	[145]
Max-interacting protein 1 (MXI1)	OTUQ9E0D	MXI1_HUMAN	Affects Response To Substance	[18]
Calcium-dependent secretion activator 2 (CADPS2)	OTV1FW0M	CAPS2_HUMAN	Affects Response To Substance	[18]
Forkhead box protein F2 (FOXF2)	OTV20NGX	FOXF2_HUMAN	Affects Response To Substance	[18]
Metastasis-associated in colon cancer protein 1 (MACC1)	OTV3DLX0	MACC1_HUMAN	Increases ADR	[120]
Glutathione S-transferase LANCL1 (LANCL1)	OTVCMZXB	LANC1_HUMAN	Affects Response To Substance	[18]
Matrilin-2 (MATN2)	OTVDR68G	MATN2_HUMAN	Affects Response To Substance	[18]
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1)	OTVIHD77	MACF1_HUMAN	Affects Response To Substance	[18]
Poly polymerase tankyrase-1 (TNKS)	OTVOUTPX	TNKS1_HUMAN	Affects Response To Substance	[18]
Ensconsin (MAP7)	OTVSSJ33	MAP7_HUMAN	Affects Response To Substance	[18]
Integrin beta-3 (ITGB3)	OTWCK1K6	ITB3_HUMAN	Increases Response To Substance	[146]
N-myc proto-oncogene protein (MYCN)	OTWD33K1	MYCN_HUMAN	Decreases Response To Substance	[147]
Sorbin and SH3 domain-containing protein 1 (SORBS1)	OTWH8762	SRBS1_HUMAN	Affects Response To Substance	[18]
Anamorsin (CIAPIN1)	OTWS90F9	CPIN1_HUMAN	Decreases Response To Substance	[148]
Inositol 1,4,5-trisphosphate receptor type 1 (ITPR1)	OTX7MWW1	ITPR1_HUMAN	Affects Response To Substance	[18]
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1)	OTX8L3M5	SAHH2_HUMAN	Affects Response To Substance	[18]
Long-chain fatty acid transport protein 3 (SLC27A3)	OTXB60L7	S27A3_HUMAN	Affects Response To Substance	[18]
Insulin-like growth factor 1 receptor (IGF1R)	OTXJIF13	IGF1R_HUMAN	Affects Response To Substance	[149]
Estrogen receptor beta (ESR2)	OTXNR2WQ	ESR2_HUMAN	Increases Response To Substance	[150]
Coiled-coil domain-containing protein 6 (CCDC6)	OTXRQDYG	CCDC6_HUMAN	Decreases Response To Substance	[151]
Arginine vasopressin-induced protein 1 (AVPI1)	OTXSBR60	AVPI1_HUMAN	Affects Response To Substance	[18]
Carbamoyl-phosphate synthase , mitochondrial (CPS1)	OTXV8NSR	CPSM_HUMAN	Affects Response To Substance	[18]
Peripheral myelin protein 22 (PMP22)	OTXWYWCZ	PMP22_HUMAN	Affects Response To Substance	[18]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (HMG20B)	OTY94WRA	HM20B_HUMAN	Affects Response To Substance	[18]
Protein Niban 1 (NIBAN1)	OTYOLI12	NIBA1_HUMAN	Affects Response To Substance	[18]
LIM and calponin homology domains-containing protein 1 (LIMCH1)	OTYPC4XA	LIMC1_HUMAN	Affects Response To Substance	[18]
Galectin-3 (LGALS3)	OTYQT0ZI	LEG3_HUMAN	Affects Response To Substance	[18]
L-dopachrome tautomerase (DCT)	OTYVNTBG	TYRP2_HUMAN	Affects Response To Substance	[18]
PRA1 family protein 3 (ARL6IP5)	OTYZ6BEQ	PRAF3_HUMAN	Increases Response To Substance	[152]
DNA (DNMT3B)	OTZ0JCNP	DNM3B_HUMAN	Decreases Response To Substance	[135]
Calcitonin (CALCA)	OTZ11LHB	CALC_HUMAN	Decreases Response To Substance	[153]
Hephaestin (HEPH)	OTZ2F15Z	HEPH_HUMAN	Affects Response To Substance	[18]
Complement decay-accelerating factor (CD55)	OTZ3HWTO	DAF_HUMAN	Affects Response To Substance	[18]
Tissue factor pathway inhibitor 2 (TFPI2)	OTZCRWOR	TFPI2_HUMAN	Affects Response To Substance	[18]
Insulin-induced gene 1 protein (INSIG1)	OTZF5X1D	INSI1_HUMAN	Affects Response To Substance	[18]
Suppressor of tumorigenicity 7 protein (ST7)	OTZG8RC6	ST7_HUMAN	Affects Response To Substance	[18]
UPF0489 protein C5orf22 (C5ORF22)	OTZN0DCX	CE022_HUMAN	Affects Response To Substance	[18]
Alkaline phosphatase, placental type (ALPP)	OTZU4G9W	PPB1_HUMAN	Affects Response To Substance	[18]
Drebrin (DBN1)	OTZVKG8A	DREB_HUMAN	Affects Response To Substance	[18]

Indication(s) of Cytarabine

Disease Entry	ICD 11	Status	REF
Acute lymphoblastic leukaemia	2A85	Approved	[6]
Acute myelogenous leukaemia	2A41	Approved	[7]
Adult acute monocytic leukemia	N.A.	Approved	[7]
Childhood acute megakaryoblastic leukemia	N.A.	Approved	[7]
Plasma cell myeloma	2A83.1	Approved	[7]
Neoplastic meningitis	N.A.	Investigative	[7]

Cytarabine Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Herpes simplex virus DNA polymerase UL30 (HSV UL30)	TTIU7X1	DPOL_HHV11	Inhibitor	[158]

Cytarabine Interacts with 6 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[159]
Organic cation transporter 1 (SLC22A1)	DTT79CX	S22A1_HUMAN	Substrate	[160]
Organic cation/carnitine transporter 1 (SLC22A4)	DT2EG60	S22A4_HUMAN	Substrate	[161]
Concentrative nucleoside transporter 1 (SLC28A1)	DT0EQPW	S28A1_HUMAN	Substrate	[162]
Equilibrative nucleoside transporter 1 (SLC29A1)	DTXD1TQ	S29A1_HUMAN	Substrate	[162]
Equilibrative nucleoside transporter 2 (SLC29A2)	DTW78DQ	S29A2_HUMAN	Substrate	[162]

Cytarabine Interacts with 5 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[163]
Cytidine aminohydrolase (CDA)	DEKEDRC	CDD_HUMAN	Metabolism	[164]
Ecto-5'-nucleotidase (NT5E)	DE3Z9HM	5NTD_HUMAN	Metabolism	[164]
Deoxycytidylate deaminase (DCTD)	DEXL3P2	DCTD_HUMAN	Metabolism	[164]
Cytidine deaminase (cdd)	DEYILK4	E0TLJ6_MYCHH	Metabolism	[165]

Cytarabine Interacts with 549 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Increases Expression	[166]
Equilibrative nucleoside transporter 1 (SLC29A1)	OTLOOZZS	S29A1_HUMAN	Decreases Response To Substance	[167]
GTP-binding protein 1 (GTPBP1)	OTA9KV6C	GTPB1_HUMAN	Increases Expression	[154]
Kinetochore protein NDC80 homolog (NDC80)	OTS7D306	NDC80_HUMAN	Increases Expression	[154]
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D)	OTIFVXWD	PDE6D_HUMAN	Decreases Expression	[154]
Lymphocyte antigen 75 (LY75)	OTDHBU0N	LY75_HUMAN	Increases Expression	[154]
ATP-dependent DNA helicase Q5 (RECQL5)	OTVZMP1Q	RECQ5_HUMAN	Decreases Expression	[154]
SLIT and NTRK-like protein 5 (SLITRK5)	OTTSUSB8	SLIK5_HUMAN	Decreases Expression	[154]
Dihydrofolate reductase (DHFR)	OT3DVIGM	DYR_HUMAN	Increases Expression	[154]
Alpha-1-antitrypsin (SERPINA1)	OTACYW9J	A1AT_HUMAN	Increases Expression	[154]
T-cell surface glycoprotein CD8 alpha chain (CD8A)	OTDWQJXK	CD8A_HUMAN	Increases Expression	[154]
Thy-1 membrane glycoprotein (THY1)	OTVONVTB	THY1_HUMAN	Decreases Expression	[154]
Serglycin (SRGN)	OTFAVSX0	SRGN_HUMAN	Increases Expression	[154]
Non-secretory ribonuclease (RNASE2)	OT8Z4FNE	RNAS2_HUMAN	Increases Expression	[154]
Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A)	OT0OUDUT	FCG2A_HUMAN	Increases Expression	[154]
Heat shock 70 kDa protein 6 (HSPA6)	OTH4S7WB	HSP76_HUMAN	Increases Expression	[154]
Transcription factor E3 (TFE3)	OTM99ZWH	TFE3_HUMAN	Increases Expression	[154]
Protein S100-P (S100P)	OTJCXNJG	S100P_HUMAN	Increases Expression	[154]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2)	OTOB6J6R	RIR2_HUMAN	Increases Expression	[154]
Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C)	OTNLMNYB	FCG2C_HUMAN	Increases Expression	[154]
G protein-coupled receptor kinase 5 (GRK5)	OTJK79EK	GRK5_HUMAN	Increases Expression	[154]
RNA-binding protein 34 (RBM34)	OTX3LUGI	RBM34_HUMAN	Decreases Expression	[154]
Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1)	OT6E2OW6	ENTP1_HUMAN	Increases Expression	[154]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10)	OT4PXBTA	TNF10_HUMAN	Increases Expression	[154]
Breast cancer type 2 susceptibility protein (BRCA2)	OTF1XSV1	BRCA2_HUMAN	Increases Expression	[154]
Geranylgeranyl transferase type-2 subunit beta (RABGGTB)	OTZ25I2W	PGTB2_HUMAN	Decreases Expression	[154]
UV excision repair protein RAD23 homolog A (RAD23A)	OTBPAWHX	RD23A_HUMAN	Decreases Expression	[154]
Ras-related protein Rab-5B (RAB5B)	OT06PN42	RAB5B_HUMAN	Increases Expression	[154]
C-X-C chemokine receptor type 4 (CXCR4)	OTUFSBX2	CXCR4_HUMAN	Increases Expression	[154]
Lysozyme C (LYZ)	OTD7H0G6	LYSC_HUMAN	Increases Expression	[154]
Histone H4 (H4C1)	OTB71W46	H4_HUMAN	Decreases Expression	[154]
DNA repair protein RAD51 homolog 1 (RAD51)	OTNVWGC1	RAD51_HUMAN	Increases Expression	[154]
Dual specificity protein phosphatase 4 (DUSP4)	OT6WAO12	DUS4_HUMAN	Decreases Expression	[154]
Src-like-adapter (SLA)	OTV17DY2	SLAP1_HUMAN	Increases Expression	[154]
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (ACAP1)	OTPFQ2QC	ACAP1_HUMAN	Increases Expression	[154]
Cytohesin-1 (CYTH1)	OTYH9NRJ	CYH1_HUMAN	Increases Expression	[154]
C3a anaphylatoxin chemotactic receptor (C3AR1)	OT8J0TF8	C3AR_HUMAN	Increases Expression	[154]
Drebrin (DBN1)	OTZVKG8A	DREB_HUMAN	Decreases Expression	[154]
DALR anticodon-binding domain-containing protein 3 (DALRD3)	OTU79VIP	DALD3_HUMAN	Decreases Expression	[154]
Equilibrative nucleobase transporter 1 (SLC43A3)	OTR60ZLA	S43A3_HUMAN	Increases Expression	[154]
Glutathione S-transferase C-terminal domain-containing protein (GSTCD)	OTIIINMT	GSTCD_HUMAN	Increases Expression	[154]
DENN domain-containing protein 1A (DENND1A)	OTONDAA0	DEN1A_HUMAN	Increases Expression	[154]
Serine protease FAM111A (FAM111A)	OTVLARLG	F111A_HUMAN	Increases Expression	[154]
Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2)	OTG6F93V	PPIP2_HUMAN	Decreases Expression	[154]
Partitioning defective 6 homolog alpha (PARD6A)	OTWLV3X1	PAR6A_HUMAN	Decreases Expression	[154]
Mediator of RNA polymerase II transcription subunit 9 (MED9)	OT59OKEJ	MED9_HUMAN	Decreases Expression	[154]
Phospholipid-transporting ATPase VD (ATP10D)	OT3JPE4H	AT10D_HUMAN	Increases Expression	[154]
Bridging integrator 2 (BIN2)	OT4S45WJ	BIN2_HUMAN	Increases Expression	[154]
DNA dC->dU-editing enzyme APOBEC-3B (APOBEC3B)	OTHLNI51	ABC3B_HUMAN	Increases Expression	[154]
Protein PRRC2C (PRRC2C)	OTBX3MXM	PRC2C_HUMAN	Decreases Expression	[154]
Odontogenic ameloblast-associated protein (ODAM)	OTT666SJ	ODAM_HUMAN	Decreases Expression	[155]
Pleckstrin homology domain-containing family G member 3 (PLEKHG3)	OTF6I8RV	PKHG3_HUMAN	Decreases Expression	[155]
Aldo-keto reductase family 1 member B15 (AKR1B15)	OTUEXSWH	AK1BF_HUMAN	Decreases Expression	[155]
Alternative prion protein (PRNP)	OTE85L1Q	APRIO_HUMAN	Decreases Expression	[155]
Matrilin-2 (MATN2)	OTVDR68G	MATN2_HUMAN	Decreases Expression	[155]
Homeobox protein Meis1 (MEIS1)	OTH9DKAD	MEIS1_HUMAN	Increases Expression	[155]
Gamma-aminobutyric acid receptor subunit pi (GABRP)	OTGKA8WS	GBRP_HUMAN	Increases Expression	[155]
Podocalyxin (PODXL)	OTPNQXF3	PODXL_HUMAN	Decreases Expression	[155]
Sarcolipin (SLN)	OTERIU75	SARCO_HUMAN	Decreases Expression	[155]
Nuclear factor 1 B-type (NFIB)	OTX94PD0	NFIB_HUMAN	Increases Expression	[155]
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF1)	OTFK8KDP	NHRF1_HUMAN	Decreases Expression	[155]
Heparan sulfate glucosamine 3-O-sulfotransferase 1 (HS3ST1)	OT5DVN9P	HS3S1_HUMAN	Decreases Expression	[155]
Tetraspanin-4 (TSPAN4)	OTKFK57F	TSN4_HUMAN	Decreases Expression	[155]
Regulator of G-protein signaling 13 (RGS13)	OTPAMQ18	RGS13_HUMAN	Decreases Expression	[155]
Surfeit locus protein 4 (SURF4)	OTCSXJ9C	SURF4_HUMAN	Decreases Expression	[155]
Monocarboxylate transporter 4 (SLC16A3)	OTDIXEXY	MOT4_HUMAN	Decreases Expression	[155]
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2)	OTP45YKX	P4HA2_HUMAN	Decreases Expression	[155]
Glycogenin-2 (GYG2)	OTAJ7YEW	GLYG2_HUMAN	Decreases Expression	[155]
Fatty acid-binding protein, brain (FABP7)	OTRE2H4G	FABP7_HUMAN	Increases Expression	[155]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2)	OTGD8TID	FLRT2_HUMAN	Decreases Expression	[155]
SLIT-ROBO Rho GTPase-activating protein 3 (SRGAP3)	OT9ZS72C	SRGP3_HUMAN	Increases Expression	[155]
Homeobox protein Hox-A2 (HOXA2)	OT6G6ZIK	HXA2_HUMAN	Increases Expression	[155]
Mothers against decapentaplegic homolog 6 (SMAD6)	OTUZZWUD	SMAD6_HUMAN	Decreases Expression	[155]
Carbonic anhydrase 12 (CA12)	OT6WNFU8	CAH12_HUMAN	Decreases Expression	[155]
Zinc finger protein SNAI2 (SNAI2)	OT7Y8EJ2	SNAI2_HUMAN	Decreases Expression	[155]
Transcription factor 21 (TCF21)	OT393IMA	TCF21_HUMAN	Decreases Expression	[155]
ER lumen protein-retaining receptor 3 (KDELR3)	OTW8C1V0	ERD23_HUMAN	Decreases Expression	[155]
Adhesion G protein-coupled receptor B3 (ADGRB3)	OT1EWGRW	AGRB3_HUMAN	Increases Expression	[155]
Protocadherin-7 (PCDH7)	OTP091X8	PCDH7_HUMAN	Decreases Expression	[155]
Suppression of tumorigenicity 18 protein (ST18)	OTPRIMTA	ST18_HUMAN	Increases Expression	[155]
TBC1 domain family member 4 (TBC1D4)	OTK66C40	TBCD4_HUMAN	Decreases Expression	[155]
Protein-tyrosine sulfotransferase 1 (TPST1)	OTDPQKEA	TPST1_HUMAN	Decreases Expression	[155]
Clathrin coat assembly protein AP180 (SNAP91)	OTE3EXWZ	AP180_HUMAN	Increases Expression	[155]
Kelch-like protein 41 (KLHL41)	OTLABE56	KLH41_HUMAN	Decreases Expression	[155]
Perilipin-3 (PLIN3)	OT9ZA7MR	PLIN3_HUMAN	Decreases Expression	[155]
P antigen family member 4 (PAGE4)	OT2VLWT0	PAGE4_HUMAN	Decreases Expression	[155]
Receptor activity-modifying protein 1 (RAMP1)	OT7UT2XB	RAMP1_HUMAN	Decreases Expression	[155]
Phosphatase and actin regulator 2 (PHACTR2)	OTWMX2A8	PHAR2_HUMAN	Decreases Expression	[155]
Leucine-rich repeat neuronal protein 2 (LRRN2)	OTGP2DCY	LRRN2_HUMAN	Decreases Expression	[155]
Cartilage-associated protein (CRTAP)	OT53H5U6	CRTAP_HUMAN	Decreases Expression	[155]
Breast cancer anti-estrogen resistance protein 3 (BCAR3)	OTPJ17M8	BCAR3_HUMAN	Decreases Expression	[155]
Matrix metalloproteinase-23 (MMP23B)	OT2OR6TS	MMP23_HUMAN	Decreases Expression	[155]
Regulator of G-protein signaling 20 (RGS20)	OT6CGYHW	RGS20_HUMAN	Increases Expression	[155]
Lymphocyte antigen 6H (LY6H)	OTTFGUD2	LY6H_HUMAN	Decreases Expression	[155]
Slit homolog 2 protein (SLIT2)	OTLS2RJ4	SLIT2_HUMAN	Decreases Expression	[155]
Sorbin and SH3 domain-containing protein 2 (SORBS2)	OTJSX44Y	SRBS2_HUMAN	Increases Expression	[155]
Glutaminase kidney isoform, mitochondrial (GLS)	OTGOZG2M	GLSK_HUMAN	Decreases Expression	[155]
SLIT and NTRK-like protein 3 (SLITRK3)	OT018P93	SLIK3_HUMAN	Decreases Expression	[155]
Myelin protein zero-like protein 1 (MPZL1)	OTJSUUHR	MPZL1_HUMAN	Decreases Expression	[155]
BAG family molecular chaperone regulator 3 (BAG3)	OTVXYUDQ	BAG3_HUMAN	Decreases Expression	[155]
EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2)	OT0I2B4J	FBLN4_HUMAN	Decreases Expression	[155]
Heart- and neural crest derivatives-expressed protein 1 (HAND1)	OTN4IPVV	HAND1_HUMAN	Decreases Expression	[155]
G1/S-specific cyclin-E2 (CCNE2)	OTBBUKQQ	CCNE2_HUMAN	Increases Expression	[155]
Cytochrome b5 (CYB5A)	OT6SN4RM	CYB5_HUMAN	Decreases Expression	[155]
Tissue-type plasminogen activator (PLAT)	OTQPDNAB	TPA_HUMAN	Decreases Expression	[155]
Serine protease inhibitor Kazal-type 1 (SPINK1)	OTSUVAL2	ISK1_HUMAN	Increases Expression	[155]
Metalloproteinase inhibitor 1 (TIMP1)	OTOXC51H	TIMP1_HUMAN	Decreases Expression	[155]
Pro-neuropeptide Y (NPY)	OT4ICV3P	NPY_HUMAN	Decreases Expression	[155]
Collagen alpha-1(I) chain (COL1A1)	OTI31178	CO1A1_HUMAN	Decreases Expression	[155]
Collagen alpha-1(III) chain (COL3A1)	OTT1EMLM	CO3A1_HUMAN	Decreases Expression	[155]
Alpha-crystallin B chain (CRYAB)	OTY4JGYU	CRYAB_HUMAN	Decreases Expression	[155]
Metallothionein-2 (MT2A)	OTHOACHD	MT2_HUMAN	Decreases Expression	[155]
Metallothionein-1A (MT1A)	OTKBH52X	MT1A_HUMAN	Decreases Expression	[155]
Metallothionein-1E (MT1E)	OTXJKU4Y	MT1E_HUMAN	Decreases Expression	[155]
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1)	OTTO6ZP4	AT1B1_HUMAN	Decreases Expression	[155]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Decreases Expression	[155]
Collagen alpha-2(V) chain (COL5A2)	OT5VOSQE	CO5A2_HUMAN	Decreases Expression	[155]
Tyrosine-protein kinase Fyn (FYN)	OTLSLVZS	FYN_HUMAN	Increases Expression	[155]
Tyrosine 3-monooxygenase (TH)	OT6ZORKP	TY3H_HUMAN	Decreases Expression	[155]
Annexin A2 (ANXA2)	OTFNS0CC	ANXA2_HUMAN	Decreases Expression	[155]
Calpain-1 catalytic subunit (CAPN1)	OTK6OQZR	CAN1_HUMAN	Decreases Expression	[155]
Decorin (DCN)	OTWLJL7K	PGS2_HUMAN	Decreases Expression	[155]
Procathepsin L (CTSL)	OTYTUW29	CATL1_HUMAN	Decreases Expression	[155]
Tyrosine-protein kinase Lyn (LYN)	OTP686K2	LYN_HUMAN	Decreases Expression	[155]
Thrombospondin-1 (THBS1)	OT0ECWK3	TSP1_HUMAN	Increases Expression	[155]
Collagen alpha-2(I) chain (COL1A2)	OTY7G382	CO1A2_HUMAN	Decreases Expression	[155]
Annexin A6 (ANXA6)	OT9KIQ0Y	ANXA6_HUMAN	Decreases Expression	[155]
Rho-related GTP-binding protein RhoC (RHOC)	OTOLE1FT	RHOC_HUMAN	Decreases Expression	[155]
Matrix Gla protein (MGP)	OTZWU3FU	MGP_HUMAN	Decreases Expression	[155]
Keratin, type I cytoskeletal 19 (KRT19)	OTDGDQ75	K1C19_HUMAN	Decreases Expression	[155]
SPARC (SPARC)	OTPN90H0	SPRC_HUMAN	Decreases Expression	[155]
Platelet-derived growth factor receptor beta (PDGFRB)	OTYSNK9Q	PGFRB_HUMAN	Decreases Expression	[155]
Homeobox protein Hox-C6 (HOXC6)	OTBCRAZV	HXC6_HUMAN	Decreases Expression	[155]
Pro-cathepsin H (CTSH)	OTLFL0DG	CATH_HUMAN	Decreases Expression	[155]
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1)	OTXOQDSG	IFIT1_HUMAN	Decreases Expression	[155]
Thymosin beta-15A (TMSB15A)	OTSBWCES	TB15A_HUMAN	Increases Expression	[155]
Ras-related protein R-Ras (RRAS)	OTBBF28C	RRAS_HUMAN	Decreases Expression	[155]
Tissue factor pathway inhibitor (TFPI)	OTA0FX16	TFPI1_HUMAN	Decreases Expression	[155]
Growth hormone receptor (GHR)	OT8WUWMU	GHR_HUMAN	Decreases Expression	[155]
Hyaluronan and proteoglycan link protein 1 (HAPLN1)	OTXWR9TJ	HPLN1_HUMAN	Decreases Expression	[155]
Microtubule-associated protein 2 (MAP2)	OT6UYT3X	MTAP2_HUMAN	Increases Expression	[155]
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)	OTA675TJ	GTR1_HUMAN	Decreases Expression	[155]
Collagen alpha-2(VI) chain (COL6A2)	OTQC6PPO	CO6A2_HUMAN	Decreases Expression	[155]
Collagen alpha-3(VI) chain (COL6A3)	OTAS6R6I	CO6A3_HUMAN	Decreases Expression	[155]
Creatine kinase B-type (CKB)	OTUCKOTT	KCRB_HUMAN	Increases Expression	[155]
Bone morphogenetic protein 4 (BMP4)	OTPZMDFH	BMP4_HUMAN	Decreases Expression	[155]
Myosin light chain 4 (MYL4)	OTURFCSE	MYL4_HUMAN	Decreases Expression	[155]
Cytochrome b-245 light chain (CYBA)	OT16N9ZO	CY24A_HUMAN	Decreases Expression	[155]
Elongation factor 2 (EEF2)	OTZ7SZ39	EF2_HUMAN	Decreases Expression	[155]
Annexin A8 (ANXA8)	OTLSSQCY	ANXA8_HUMAN	Decreases Expression	[155]
Beta-enolase (ENO3)	OT3HYKYI	ENOB_HUMAN	Decreases Expression	[155]
Ezrin (EZR)	OTHBPF1Z	EZRI_HUMAN	Decreases Expression	[155]
N-chimaerin (CHN1)	OTM196M3	CHIN_HUMAN	Decreases Expression	[155]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Decreases Expression	[155]
Histone H1.2 (H1-2)	OT0AVI4M	H12_HUMAN	Decreases Expression	[155]
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (GNB3)	OTA6HYBA	GBB3_HUMAN	Decreases Expression	[155]
Natriuretic peptides B (NPPB)	OTSN2IPY	ANFB_HUMAN	Increases Expression	[155]
Homeobox protein Hox-B8 (HOXB8)	OTKHOD17	HXB8_HUMAN	Decreases Expression	[155]
Homeobox protein Hox-B4 (HOXB4)	OTH1HRW5	HXB4_HUMAN	Decreases Expression	[155]
Homeobox protein Hox-B6 (HOXB6)	OT3TFQ0U	HXB6_HUMAN	Decreases Expression	[155]
Neuromodulin (GAP43)	OT2OTGGV	NEUM_HUMAN	Increases Expression	[155]
Insulin-like growth factor-binding protein 3 (IGFBP3)	OTIX63TX	IBP3_HUMAN	Decreases Expression	[155]
Integrin beta-5 (ITGB5)	OT21MF51	ITB5_HUMAN	Decreases Expression	[155]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3)	OTC1UOHP	ATF3_HUMAN	Decreases Expression	[155]
Protachykinin-1 (TAC1)	OTM842YW	TKN1_HUMAN	Increases Expression	[155]
Homeobox protein Hox-A5 (HOXA5)	OTLWGPQD	HXA5_HUMAN	Increases Expression	[155]
Ephrin-A1 (EFNA1)	OTU2NUA2	EFNA1_HUMAN	Decreases Expression	[155]
Collagen alpha-1(IX) chain (COL9A1)	OTWBR27Y	CO9A1_HUMAN	Increases Expression	[155]
Collagen alpha-1(V) chain (COL5A1)	OT24078H	CO5A1_HUMAN	Decreases Expression	[155]
Cannabinoid receptor 1 (CNR1)	OTEALO6G	CNR1_HUMAN	Increases Expression	[155]
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)	OTVLI4DD	TNAP3_HUMAN	Decreases Expression	[155]
Midkine (MDK)	OTF24HKC	MK_HUMAN	Decreases Expression	[155]
Bone morphogenetic protein 5 (BMP5)	OTC0Y6E0	BMP5_HUMAN	Decreases Expression	[155]
Cadherin-3 (CDH3)	OTKNLQU7	CADH3_HUMAN	Decreases Expression	[155]
Calretinin (CALB2)	OTSNMCG9	CALB2_HUMAN	Decreases Expression	[155]
Fibulin-1 (FBLN1)	OT5MHHOP	FBLN1_HUMAN	Decreases Expression	[155]
Receptor-type tyrosine-protein phosphatase zeta (PTPRZ1)	OT2NRISU	PTPRZ_HUMAN	Increases Expression	[155]
Insulin-like growth factor-binding protein 5 (IGFBP5)	OTRE5V0C	IBP5_HUMAN	Decreases Expression	[155]
Paired box protein Pax-6 (PAX6)	OTOC9876	PAX6_HUMAN	Increases Expression	[155]
Protein S100-A4 (S100A4)	OTLRGFSQ	S10A4_HUMAN	Decreases Expression	[155]
Ciliary neurotrophic factor receptor subunit alpha (CNTFR)	OT3B1RGG	CNTFR_HUMAN	Increases Expression	[155]
Stomatin (STOM)	OTC8R6EH	STOM_HUMAN	Decreases Expression	[155]
Protein-lysine 6-oxidase (LOX)	OT1C2HIU	LYOX_HUMAN	Decreases Expression	[155]
Homeobox protein MSX-1 (MSX1)	OT5U41ZP	MSX1_HUMAN	Decreases Expression	[155]
Grancalcin (GCA)	OTAJ7ZHG	GRAN_HUMAN	Decreases Expression	[155]
Cellular retinoic acid-binding protein 1 (CRABP1)	OTISDG5X	RABP1_HUMAN	Increases Expression	[155]
Aquaporin-1 (AQP1)	OTX5MYX9	AQP1_HUMAN	Decreases Expression	[155]
G1/S-specific cyclin-D3 (CCND3)	OTNKPQ22	CCND3_HUMAN	Decreases Expression	[155]
Tyrosine-protein kinase receptor UFO (AXL)	OTKA2SUX	UFO_HUMAN	Decreases Expression	[155]
Translocator protein (TSPO)	OTSU7ESK	TSPO_HUMAN	Decreases Expression	[155]
Gastrin-releasing peptide receptor (GRPR)	OTBQGYJT	GRPR_HUMAN	Decreases Expression	[155]
Homeobox protein Hox-C8 (HOXC8)	OTJUYU8J	HXC8_HUMAN	Decreases Expression	[155]
Syndecan-4 (SDC4)	OTKUVUGZ	SDC4_HUMAN	Decreases Expression	[155]
Dimethylaniline monooxygenase 4 (FMO4)	OT5UYZL7	FMO4_HUMAN	Decreases Expression	[155]
Gastrin/cholecystokinin type B receptor (CCKBR)	OTQSNXOI	GASR_HUMAN	Decreases Expression	[155]
Serpin B6 (SERPINB6)	OT7G55IK	SPB6_HUMAN	Decreases Expression	[155]
Apelin receptor (APLNR)	OT8585HU	APJ_HUMAN	Decreases Expression	[155]
Copper-transporting ATPase 2 (ATP7B)	OTPWLNCO	ATP7B_HUMAN	Decreases Expression	[155]
Collagen alpha-1(XVIII) chain (COL18A1)	OTJFUH6O	COIA1_HUMAN	Decreases Expression	[155]
Melanocyte protein PMEL (PMEL)	OTCDDHHM	PMEL_HUMAN	Increases Expression	[155]
Peripherin (PRPH)	OT6VUH78	PERI_HUMAN	Decreases Expression	[155]
Transcription factor SOX-3 (SOX3)	OT1CRCOB	SOX3_HUMAN	Increases Expression	[155]
Glutamate receptor 2 (GRIA2)	OT5N1WB7	GRIA2_HUMAN	Increases Expression	[155]
Troponin T, cardiac muscle (TNNT2)	OT80NN7R	TNNT2_HUMAN	Decreases Expression	[155]
Peptidyl-prolyl cis-trans isomerase C (PPIC)	OTY5Q42N	PPIC_HUMAN	Decreases Expression	[155]
Leptin receptor (LEPR)	OT9H7G0C	LEPR_HUMAN	Decreases Expression	[155]
Neuromedin-U (NMU)	OTW9X7BQ	NMU_HUMAN	Increases Expression	[155]
Nestin (NES)	OTZ9PZ14	NEST_HUMAN	Increases Expression	[155]
Casein kinase I isoform delta (CSNK1D)	OTNF4S77	KC1D_HUMAN	Decreases Expression	[155]
CCAAT/enhancer-binding protein delta (CEBPD)	OTNBIPMY	CEBPD_HUMAN	Decreases Expression	[155]
Regulator of G-protein signaling 4 (RGS4)	OTG94HHL	RGS4_HUMAN	Decreases Expression	[155]
Cyclin-dependent kinase inhibitor 1C (CDKN1C)	OTASTJ3Q	CDN1C_HUMAN	Decreases Expression	[155]
Serpin B9 (SERPINB9)	OTJ811IF	SPB9_HUMAN	Decreases Expression	[155]
Serpin H1 (SERPINH1)	OTKGI7BS	SERPH_HUMAN	Decreases Expression	[155]
Ras association domain-containing protein 2 (RASSF2)	OT2JHDO4	RASF2_HUMAN	Increases Expression	[155]
Lipopolysaccharide-responsive and beige-like anchor protein (LRBA)	OTOUZN9G	LRBA_HUMAN	Decreases Expression	[155]
RNA-binding protein Nova-1 (NOVA1)	OT6A9KHY	NOVA1_HUMAN	Increases Expression	[155]
Neuronal membrane glycoprotein M6-a (GPM6A)	OT8G13EG	GPM6A_HUMAN	Increases Expression	[155]
Lumican (LUM)	OTSRC874	LUM_HUMAN	Decreases Expression	[155]
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3)	OT4O4NFS	ROA3_HUMAN	Decreases Expression	[155]
Rho GDP-dissociation inhibitor 2 (ARHGDIB)	OT9PD6CS	GDIR2_HUMAN	Decreases Expression	[155]
Cationic amino acid transporter 2 (SLC7A2)	OTAMWBVM	CTR2_HUMAN	Decreases Expression	[155]
Atrophin-1 (ATN1)	OTNZFLKY	ATN1_HUMAN	Increases Expression	[155]
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (PDE1A)	OTU7J3F7	PDE1A_HUMAN	Increases Expression	[155]
Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMGCS2)	OTC3RUN9	HMCS2_HUMAN	Decreases Expression	[155]
Phospholipid transfer protein (PLTP)	OTVJJO5Z	PLTP_HUMAN	Decreases Expression	[155]
Microfibril-associated glycoprotein 4 (MFAP4)	OT5W64QY	MFAP4_HUMAN	Decreases Expression	[155]
Cadherin-11 (CDH11)	OTIZKPTF	CAD11_HUMAN	Decreases Expression	[155]
Claudin-15 (CLDN15)	OT9K0KI7	CLD15_HUMAN	Decreases Expression	[155]
Junctional adhesion molecule B (JAM2)	OTHVJJRJ	JAM2_HUMAN	Increases Expression	[155]
Myelin proteolipid protein (PLP1)	OT8CM9CX	MYPR_HUMAN	Increases Expression	[155]
Protein S100-A10 (S100A10)	OTI71243	S10AA_HUMAN	Decreases Expression	[155]
Heart- and neural crest derivatives-expressed protein 2 (HAND2)	OTCXYW4Y	HAND2_HUMAN	Decreases Expression	[155]
Neurocalcin-delta (NCALD)	OTJZ8UEL	NCALD_HUMAN	Increases Expression	[155]
cAMP-dependent protein kinase inhibitor alpha (PKIA)	OT8M5GVO	IPKA_HUMAN	Decreases Expression	[155]
Actin, alpha cardiac muscle 1 (ACTC1)	OTJU04B1	ACTC_HUMAN	Decreases Expression	[155]
Actin, alpha skeletal muscle (ACTA1)	OTOVGLPG	ACTS_HUMAN	Increases Expression	[155]
Pituitary homeobox 1 (PITX1)	OTA0UN4C	PITX1_HUMAN	Decreases Expression	[155]
Oxidized low-density lipoprotein receptor 1 (OLR1)	OTS44RIC	OLR1_HUMAN	Decreases Expression	[155]
Iroquois-class homeodomain protein IRX-5 (IRX5)	OT05J514	IRX5_HUMAN	Increases Expression	[155]
Reelin (RELN)	OTLKMW1O	RELN_HUMAN	Decreases Expression	[155]
Arginase-2, mitochondrial (ARG2)	OTCPI0E8	ARGI2_HUMAN	Decreases Expression	[155]
Metallothionein-1X (MT1X)	OT9AKFVS	MT1X_HUMAN	Decreases Expression	[155]
Matrix-remodeling-associated protein 7 (MXRA7)	OTVQLYIY	MXRA7_HUMAN	Decreases Expression	[155]
Disabled homolog 2 (DAB2)	OTRMQTMZ	DAB2_HUMAN	Decreases Expression	[155]
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (PDE1B)	OT9NPJCR	PDE1B_HUMAN	Increases Expression	[155]
Myosin regulatory light chain 2, atrial isoform (MYL7)	OT7ZNDP4	MLRA_HUMAN	Decreases Expression	[155]
Peripheral myelin protein 22 (PMP22)	OTXWYWCZ	PMP22_HUMAN	Decreases Expression	[155]
Flavin-containing monooxygenase 1 (FMO1)	OTTHSQKP	FMO1_HUMAN	Decreases Expression	[155]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP)	OTFP7AA8	PFKAP_HUMAN	Decreases Expression	[155]
Zinc finger protein basonuclin-1 (BNC1)	OTGJ5WUF	BNC1_HUMAN	Decreases Expression	[155]
Transgelin (TAGLN)	OTAEZ0KP	TAGL_HUMAN	Increases Expression	[155]
Guanylate cyclase soluble subunit alpha-1 (GUCY1A1)	OTPTCBUN	GCYA1_HUMAN	Decreases Expression	[155]
Sterol 26-hydroxylase, mitochondrial (CYP27A1)	OT649C01	CP27A_HUMAN	Decreases Expression	[155]
Desmocollin-2 (DSC2)	OTODVH8K	DSC2_HUMAN	Decreases Expression	[155]
Angiopoietin-1 receptor (TEK)	OT78YN57	TIE2_HUMAN	Decreases Expression	[155]
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1)	OT3ZIANF	PLOD1_HUMAN	Decreases Expression	[155]
Transforming growth factor beta receptor type 3 (TGFBR3)	OTQOOUC4	TGBR3_HUMAN	Decreases Expression	[155]
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)	OTQF5ZAK	PTH1R_HUMAN	Decreases Expression	[155]
MBT domain-containing protein 1 (MBTD1)	OT2P6943	MBTD1_HUMAN	Increases Expression	[155]
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B)	OTOA8WU2	PDE4B_HUMAN	Increases Expression	[155]
Trefoil factor 3 (TFF3)	OTJJDRTU	TFF3_HUMAN	Increases Expression	[155]
Regulator of G-protein signaling 1 (RGS1)	OTGXJYMG	RGS1_HUMAN	Decreases Expression	[155]
Neuroblast differentiation-associated protein AHNAK (AHNAK)	OT6KH1WG	AHNK_HUMAN	Decreases Expression	[155]
Coiled-coil domain-containing protein 15 (CCDC15)	OT1NZX84	CCD15_HUMAN	Increases Expression	[155]
Transmembrane protein 62 (TMEM62)	OTJ4SPCM	TMM62_HUMAN	Increases Expression	[155]
Bone marrow stromal antigen 2 (BST2)	OTU4LCJV	BST2_HUMAN	Decreases Expression	[155]
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3GAL1)	OTFCO8QX	SIA4A_HUMAN	Decreases Expression	[155]
Tyrosine-protein kinase Mer (MERTK)	OTWBRAJ6	MERTK_HUMAN	Decreases Expression	[155]
Transmembrane emp24 domain-containing protein 1 (TMED1)	OTWSH0J8	TMED1_HUMAN	Decreases Expression	[155]
Filamin-C (FLNC)	OT3F8J6Y	FLNC_HUMAN	Decreases Expression	[155]
Transforming growth factor beta activator LRRC32 (LRRC32)	OTG7EDZL	LRC32_HUMAN	Decreases Expression	[155]
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H (PIGH)	OTMCFF0K	PIGH_HUMAN	Decreases Expression	[155]
Desmocollin-3 (DSC3)	OTYG47F8	DSC3_HUMAN	Decreases Expression	[155]
Eukaryotic translation initiation factor 4H (EIF4H)	OTGZI072	IF4H_HUMAN	Decreases Expression	[155]
Periostin (POSTN)	OTWP62UA	POSTN_HUMAN	Decreases Expression	[155]
Phosphoglucomutase-like protein 5 (PGM5)	OTEAS7OC	PGM5_HUMAN	Decreases Expression	[155]
Nicotinate-nucleotide pyrophosphorylase (QPRT)	OT6SKKLL	NADC_HUMAN	Decreases Expression	[155]
Leucine-rich repeat-containing protein 41 (LRRC41)	OT4YSBV5	LRC41_HUMAN	Decreases Expression	[155]
Delta(24)-sterol reductase (DHCR24)	OTP301JW	DHC24_HUMAN	Decreases Expression	[155]
Probable G-protein coupled receptor 19 (GPR19)	OTR7MUS5	GPR19_HUMAN	Increases Expression	[155]
Alpha-internexin (INA)	OT1D33T4	AINX_HUMAN	Increases Expression	[155]
Kynureninase (KYNU)	OTINL2RE	KYNU_HUMAN	Decreases Expression	[155]
Thiosulfate sulfurtransferase (TST)	OTZ4F5LK	THTR_HUMAN	Decreases Expression	[155]
Reticulon-1 (RTN1)	OTCX1SMK	RTN1_HUMAN	Increases Expression	[155]
Discoidin domain-containing receptor 2 (DDR2)	OT9IHOGZ	DDR2_HUMAN	Decreases Expression	[155]
Rho GTPase-activating protein 44 (ARHGAP44)	OTHJUCO1	RHG44_HUMAN	Decreases Expression	[155]
Sodium-coupled monocarboxylate transporter 2 (SLC5A12)	OTKY9NAL	SC5AC_HUMAN	Decreases Expression	[155]
Keratin, type I cytoskeletal 24 (KRT24)	OTR7MT1E	K1C24_HUMAN	Decreases Expression	[155]
Electroneutral sodium bicarbonate exchanger 1 (SLC4A8)	OTKJ0X6Q	S4A8_HUMAN	Decreases Expression	[155]
HLA class II histocompatibility antigen, DR beta 5 chain (HLA-DRB5)	OTUX5TWM	DRB5_HUMAN	Decreases Expression	[155]
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 (MINDY4)	OTBZ2SZB	MINY4_HUMAN	Decreases Expression	[155]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1)	OT6Z1L2E	PLCH1_HUMAN	Increases Expression	[155]
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (SVEP1)	OTOBICRD	SVEP1_HUMAN	Decreases Expression	[155]
PDZ and LIM domain protein 3 (PDLIM3)	OTVXQC81	PDLI3_HUMAN	Increases Expression	[155]
Protein LBH (LBH)	OT87AT1X	LBH_HUMAN	Decreases Expression	[155]
Cordon-bleu protein-like 1 (COBLL1)	OTQFN1TC	COBL1_HUMAN	Decreases Expression	[155]
Spindlin-4 (SPIN4)	OT09ZWHM	SPIN4_HUMAN	Decreases Expression	[155]
Trans-2,3-enoyl-CoA reductase-like (TECRL)	OTXLSNCP	TECRL_HUMAN	Decreases Expression	[155]
Placenta-specific protein 9 (PLAC9)	OTZHIJ44	PLAC9_HUMAN	Decreases Expression	[155]
Collectin-12 (COLEC12)	OTIQTK9G	COL12_HUMAN	Decreases Expression	[155]
CUGBP Elav-like family member 3 (CELF3)	OTTP45WK	CELF3_HUMAN	Increases Expression	[155]
KN motif and ankyrin repeat domain-containing protein 4 (KANK4)	OT5WC0Q8	KANK4_HUMAN	Decreases Expression	[155]
Transcription factor HES-5 (HES5)	OTW7JEHV	HES5_HUMAN	Increases Expression	[155]
Collagen alpha-1(XIII) chain (COL13A1)	OTM9IM6J	CODA1_HUMAN	Decreases Expression	[155]
Terminal nucleotidyltransferase 5C (TENT5C)	OTOWVQ4O	TET5C_HUMAN	Decreases Expression	[155]
FYN-binding protein 2 (FYB2)	OTA3NG8M	FYB2_HUMAN	Decreases Expression	[155]
F-actin-uncapping protein LRRC16A (CARMIL1)	OT1A5IX5	CARL1_HUMAN	Decreases Expression	[155]
Pikachurin (EGFLAM)	OTACZZJ0	EGFLA_HUMAN	Decreases Expression	[155]
Carboxypeptidase Z (CPZ)	OT5HUR28	CBPZ_HUMAN	Decreases Expression	[155]
NADH-cytochrome b5 reductase 2 (CYB5R2)	OTTLM7XN	NB5R2_HUMAN	Decreases Expression	[155]
Repulsive guidance molecule B (RGMB)	OT2DROYU	RGMB_HUMAN	Increases Expression	[155]
Caveolae-associated protein 1 (CAVIN1)	OTFO915U	CAVN1_HUMAN	Decreases Expression	[155]
Cdc42 effector protein 5 (CDC42EP5)	OTQQDUCD	BORG3_HUMAN	Decreases Expression	[155]
Cytochrome b5 domain-containing protein 1 (CYB5D1)	OTSZWTPT	CB5D1_HUMAN	Decreases Expression	[155]
Transmembrane protein 88 (TMEM88)	OTA96YEL	TMM88_HUMAN	Decreases Expression	[155]
Protein cornichon homolog 2 (CNIH2)	OTT2ECCW	CNIH2_HUMAN	Increases Expression	[155]
Prostate androgen-regulated mucin-like protein 1 (PARM1)	OTDNK7EX	PARM1_HUMAN	Decreases Expression	[155]
Inactive serine protease PAMR1 (PAMR1)	OT83ZH5U	PAMR1_HUMAN	Decreases Expression	[155]
R-spondin-2 (RSPO2)	OT3HHXU0	RSPO2_HUMAN	Decreases Expression	[155]
Zinc finger protein basonuclin-2 (BNC2)	OTU22H9Z	BNC2_HUMAN	Decreases Expression	[155]
Staphylococcal nuclease domain-containing protein 1 (SND1)	OTT734JN	SND1_HUMAN	Decreases Expression	[155]
Monocarboxylate transporter 9 (SLC16A9)	OTVCLKQQ	MOT9_HUMAN	Increases Expression	[155]
Centriolin (CNTRL)	OTQI3VBA	CNTRL_HUMAN	Increases Expression	[155]
Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1)	OTKCR5XL	CK2N1_HUMAN	Increases Expression	[155]
Schlafen family member 11 (SLFN11)	OTJWFPMY	SLN11_HUMAN	Increases Expression	[155]
Polypeptide N-acetylgalactosaminyltransferase 10 (GALNT10)	OTZ6FDOL	GLT10_HUMAN	Decreases Expression	[155]
Alpha-protein kinase 2 (ALPK2)	OTWZZDQ9	ALPK2_HUMAN	Decreases Expression	[155]
E3 ubiquitin-protein ligase MARCHF3 (MARCHF3)	OT89V4N5	MARH3_HUMAN	Decreases Expression	[155]
Transmembrane protein 200A (TMEM200A)	OTVJZIOR	T200A_HUMAN	Decreases Expression	[155]
Podoplanin (PDPN)	OTBUV19I	PDPN_HUMAN	Decreases Expression	[155]
Rhophilin-2 (RHPN2)	OTTYWMF6	RHPN2_HUMAN	Decreases Expression	[155]
Epidermal growth factor-like protein 6 (EGFL6)	OT331X59	EGFL6_HUMAN	Decreases Expression	[155]
5'-3' exonuclease PLD3 (PLD3)	OTL07SP2	PLD3_HUMAN	Decreases Expression	[155]
Neuron navigator 2 (NAV2)	OTGAOL01	NAV2_HUMAN	Decreases Expression	[155]
Somatomedin-B and thrombospondin type-1 domain-containing protein (SBSPON)	OTBHAW5K	SBSPO_HUMAN	Decreases Expression	[155]
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2)	OTRUIMC4	GNT2A_HUMAN	Decreases Expression	[155]
Sperm-associated antigen 16 protein (SPAG16)	OTIFUPYD	SPG16_HUMAN	Increases Expression	[155]
Cytochrome P450 4X1 (CYP4X1)	OTMTEUNE	CP4X1_HUMAN	Decreases Expression	[155]
Inactive serine protease 35 (PRSS35)	OT09H6WH	PRS35_HUMAN	Decreases Expression	[155]
Secreted frizzled-related protein 1 (SFRP1)	OT0U9G41	SFRP1_HUMAN	Increases Expression	[155]
Reprimo-like protein (RPRML)	OTPOESFN	RPRML_HUMAN	Increases Expression	[155]
Actin filament-associated protein 1-like 2 (AFAP1L2)	OTJBI0VN	AF1L2_HUMAN	Decreases Expression	[155]
Protocadherin-20 (PCDH20)	OTFSNRXK	PCD20_HUMAN	Decreases Expression	[155]
Fibrous sheath-interacting protein 1 (FSIP1)	OTYLL6GM	FSIP1_HUMAN	Increases Expression	[155]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (ST6GALNAC3)	OTLAQ14Q	SIA7C_HUMAN	Decreases Expression	[155]
Trinucleotide repeat-containing gene 6A protein (TNRC6A)	OT493IOM	TNR6A_HUMAN	Increases Expression	[155]
Coiled-coil domain-containing protein 112 (CCDC112)	OT3OEYG6	CC112_HUMAN	Increases Expression	[155]
Class E basic helix-loop-helix protein 22 (BHLHE22)	OTZUQY5L	BHE22_HUMAN	Increases Expression	[155]
Secretory carrier-associated membrane protein 5 (SCAMP5)	OT9MXA2J	SCAM5_HUMAN	Increases Expression	[155]
Protein odd-skipped-related 1 (OSR1)	OTB19LEQ	OSR1_HUMAN	Decreases Expression	[155]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Decreases Expression	[155]
Protein MGARP (MGARP)	OTL90XO8	HUMMR_HUMAN	Decreases Expression	[155]
Mucolipin-3 (MCOLN3)	OTCRPRVS	MCLN3_HUMAN	Decreases Expression	[155]
Breast carcinoma-amplified sequence 4 (BCAS4)	OT596N5E	BCAS4_HUMAN	Decreases Expression	[155]
E3 ubiquitin-protein ligase SH3RF2 (SH3RF2)	OT2IVOK4	SH3R2_HUMAN	Decreases Expression	[155]
Docking protein 4 (DOK4)	OTUEWLG8	DOK4_HUMAN	Decreases Expression	[155]
Probable phospholipid-transporting ATPase IM (ATP8B4)	OT48TSYO	AT8B4_HUMAN	Decreases Expression	[155]
Cell migration-inducing and hyaluronan-binding protein (CEMIP)	OTK80FYN	CEMIP_HUMAN	Decreases Expression	[155]
Leucine-rich repeat neuronal protein 4 (LRRN4)	OTC2T1MP	LRRN4_HUMAN	Decreases Expression	[155]
Selenoprotein M (SELENOM)	OTJ7PORS	SELM_HUMAN	Decreases Expression	[155]
Atlastin-1 (ATL1)	OTR2788Y	ATLA1_HUMAN	Increases Expression	[155]
E3 ubiquitin-protein ligase MYLIP (MYLIP)	OTL0PFGV	MYLIP_HUMAN	Decreases Expression	[155]
Cyclic GMP-AMP phosphodiesterase SMPDL3A (SMPDL3A)	OTQDYH8E	ASM3A_HUMAN	Decreases Expression	[155]
SEC14-like protein 1 (SEC14L1)	OTA75FET	S14L1_HUMAN	Decreases Expression	[155]
Protein NDRG1 (NDRG1)	OTVO66BO	NDRG1_HUMAN	Decreases Expression	[155]
Ankyrin repeat and SAM domain-containing protein 1A (ANKS1A)	OTYZP3MP	ANS1A_HUMAN	Decreases Expression	[155]
Serine protease HTRA1 (HTRA1)	OTR8ACBF	HTRA1_HUMAN	Decreases Expression	[155]
Secreted frizzled-related protein 3 (FRZB)	OTTO3DPY	SFRP3_HUMAN	Decreases Expression	[155]
Hyaluronan synthase 2 (HAS2)	OTTD3PAL	HYAS2_HUMAN	Decreases Expression	[155]
Proprotein convertase subtilisin/kexin type 5 (PCSK5)	OTP0RJ4Y	PCSK5_HUMAN	Decreases Expression	[155]
Kallikrein-6 (KLK6)	OTIEA234	KLK6_HUMAN	Decreases Expression	[155]
Exostosin-2 (EXT2)	OT8IR5QN	EXT2_HUMAN	Decreases Expression	[155]
Ecto-ADP-ribosyltransferase 4 (ART4)	OTTV2J54	NAR4_HUMAN	Decreases Expression	[155]
Caveolae-associated protein 3 (CAVIN3)	OTOLBK79	CAVN3_HUMAN	Decreases Expression	[155]
Myeloid-derived growth factor (MYDGF)	OT9HRPL6	MYDGF_HUMAN	Decreases Expression	[155]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (ST6GALNAC6)	OT3C3VWX	SIA7F_HUMAN	Decreases Expression	[155]
Coiled-coil domain-containing protein 102A (CCDC102A)	OTT7XHIP	C102A_HUMAN	Decreases Expression	[155]
Ras-related and estrogen-regulated growth inhibitor (RERG)	OTF6MMLV	RERG_HUMAN	Decreases Expression	[155]
Ras-related protein Rab-37 (RAB37)	OTRL8IUO	RAB37_HUMAN	Decreases Expression	[155]
Store-operated calcium entry-associated regulatory factor (SARAF)	OTH5JIFE	SARAF_HUMAN	Decreases Expression	[155]
BTB/POZ domain-containing protein KCTD12 (KCTD12)	OTPYKT4Z	KCD12_HUMAN	Decreases Expression	[155]
Multivesicular body subunit 12A (MVB12A)	OT3737K0	MB12A_HUMAN	Decreases Expression	[155]
E3 ubiquitin-protein ligase pellino homolog 1 (PELI1)	OTMLBCLC	PELI1_HUMAN	Increases Expression	[155]
Phytanoyl-CoA hydroxylase-interacting protein-like (PHYHIPL)	OT9EIUGH	PHIPL_HUMAN	Increases Expression	[155]
Multidrug and toxin extrusion protein 1 (SLC47A1)	OTZX0U5Q	S47A1_HUMAN	Decreases Expression	[155]
Vacuolar-sorting protein SNF8 (SNF8)	OTRQA2AI	SNF8_HUMAN	Decreases Expression	[155]
Secreted frizzled-related protein 2 (SFRP2)	OT8GZ0CA	SFRP2_HUMAN	Increases Expression	[155]
PC-esterase domain-containing protein 1B (PCED1B)	OT19CDAB	PED1B_HUMAN	Decreases Expression	[155]
Terminal nucleotidyltransferase 5A (TENT5A)	OTSYF511	TET5A_HUMAN	Decreases Expression	[155]
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1)	OTY5HZN5	LRIG1_HUMAN	Increases Expression	[155]
Lysyl oxidase homolog 4 (LOXL4)	OT6XY2JL	LOXL4_HUMAN	Decreases Expression	[155]
Multiple epidermal growth factor-like domains protein 10 (MEGF10)	OTILSPJ6	MEG10_HUMAN	Increases Expression	[155]
N-terminal kinase-like protein (SCYL1)	OTQ0IN7P	SCYL1_HUMAN	Decreases Expression	[155]
Ecto-ADP-ribosyltransferase 5 (ART5)	OTEZUT8V	NAR5_HUMAN	Decreases Expression	[155]
Protein phosphatase 1M (PPM1M)	OTCPLZQ7	PPM1M_HUMAN	Decreases Expression	[155]
Roundabout homolog 3 (ROBO3)	OTPVG40S	ROBO3_HUMAN	Increases Expression	[155]
Prickle-like protein 1 (PRICKLE1)	OT9HHEM9	PRIC1_HUMAN	Decreases Expression	[155]
Leucine-rich repeat and fibronectin type-III domain-containing protein 5 (LRFN5)	OTK7QZ3B	LRFN5_HUMAN	Decreases Expression	[155]
Guanylate-binding protein 4 (GBP4)	OTSPNGKX	GBP4_HUMAN	Decreases Expression	[155]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (MAGI1)	OTMV4ASV	MAGI1_HUMAN	Increases Expression	[155]
Myeloid-associated differentiation marker (MYADM)	OTZTZI7P	MYADM_HUMAN	Decreases Expression	[155]
Protein Niban 2 (NIBAN2)	OTVDQSPI	NIBA2_HUMAN	Decreases Expression	[155]
Transcription factor 12 (TCF12)	OTZVONNU	HTF4_HUMAN	Increases Expression	[155]
Protein kinase C-binding protein NELL2 (NELL2)	OTS4MJZ7	NELL2_HUMAN	Increases Expression	[155]
G-protein coupled estrogen receptor 1 (GPER1)	OTUK0TDC	GPER1_HUMAN	Decreases Expression	[155]
Pituitary homeobox 2 (PITX2)	OTWMXAOY	PITX2_HUMAN	Decreases Expression	[155]
Plakophilin-2 (PKP2)	OTJOVF68	PKP2_HUMAN	Decreases Expression	[155]
Cbp/p300-interacting transactivator 2 (CITED2)	OT812TV7	CITE2_HUMAN	Decreases Expression	[155]
Ribosome quality control complex subunit TCF25 (TCF25)	OTTFHHU9	TCF25_HUMAN	Decreases Expression	[155]
Allograft inflammatory factor 1-like (AIF1L)	OTDEOB80	AIF1L_HUMAN	Increases Expression	[155]
SH3-containing GRB2-like protein 3-interacting protein 1 (SGIP1)	OTQW6R3Z	SGIP1_HUMAN	Increases Expression	[155]
Transcription elongation factor A protein-like 7 (TCEAL7)	OTNPDZCN	TCAL7_HUMAN	Increases Expression	[155]
Histone H2A.J (H2AJ)	OTVA4XTW	H2AJ_HUMAN	Decreases Expression	[155]
Ribonuclease P protein subunit p25 (RPP25)	OTEN6QN7	RPP25_HUMAN	Decreases Expression	[155]
EF-hand domain-containing protein D1 (EFHD1)	OTL5INE4	EFHD1_HUMAN	Decreases Expression	[155]
Arginine/serine-rich protein 1 (RSRP1)	OTOAZLCL	RSRP1_HUMAN	Decreases Expression	[155]
Transmembrane emp24 domain-containing protein 9 (TMED9)	OTYGAQS0	TMED9_HUMAN	Decreases Expression	[155]
Max dimerization protein 3 (MXD3)	OT4U88UP	MAD3_HUMAN	Increases Expression	[155]
Transcription factor GATA-5 (GATA5)	OTO81B63	GATA5_HUMAN	Decreases Expression	[155]
Oxysterol-binding protein-related protein 10 (OSBPL10)	OT0TFMBE	OSB10_HUMAN	Decreases Expression	[155]
Uncharacterized protein KIAA1671 (KIAA1671)	OTYGNSCG	K1671_HUMAN	Decreases Expression	[155]
Tripartite motif-containing protein 6 (TRIM6)	OTBSMX0B	TRIM6_HUMAN	Decreases Expression	[155]
Tripartite motif-containing protein 5 (TRIM5)	OTMZH7EJ	TRIM5_HUMAN	Decreases Expression	[155]
RNA exonuclease 4 (REXO4)	OT2NNFKZ	REXO4_HUMAN	Decreases Expression	[155]
Disintegrin and metalloproteinase domain-containing protein 19 (ADAM19)	OTH88TXU	ADA19_HUMAN	Decreases Expression	[155]
Cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2)	OTVSFHTL	CRLD2_HUMAN	Decreases Expression	[155]
Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1)	OT4U7SBG	GBRL1_HUMAN	Decreases Expression	[155]
Small conductance calcium-activated potassium channel protein 2 (KCNN2)	OTQVTMK5	KCNN2_HUMAN	Decreases Expression	[155]
Thiamin pyrophosphokinase 1 (TPK1)	OTCHPUD0	TPK1_HUMAN	Decreases Expression	[155]
SPARC-related modular calcium-binding protein 2 (SMOC2)	OTK1EQ49	SMOC2_HUMAN	Decreases Expression	[155]
Leucine-rich repeat neuronal protein 3 (LRRN3)	OT7X0AA7	LRRN3_HUMAN	Increases Expression	[155]
RWD domain-containing protein 1 (RWDD1)	OTVEZWQG	RWDD1_HUMAN	Increases Expression	[155]
Calcium-binding protein 39-like (CAB39L)	OTQEBL0W	CB39L_HUMAN	Decreases Expression	[155]
Spondin-1 (SPON1)	OTC06MY4	SPON1_HUMAN	Decreases Expression	[155]
Anoctamin-8 (ANO8)	OT07SRRX	ANO8_HUMAN	Increases Expression	[155]
Synaptotagmin-like protein 2 (SYTL2)	OTUIOWKL	SYTL2_HUMAN	Increases Expression	[155]
Solute carrier family 40 member 1 (SLC40A1)	OT8RV2VY	S40A1_HUMAN	Decreases Expression	[155]
Zinc transporter ZIP2 (SLC39A2)	OTE0GI4W	S39A2_HUMAN	Decreases Expression	[155]
NADPH oxidase 4 (NOX4)	OTTYQ097	NOX4_HUMAN	Decreases Expression	[155]
Nuclear receptor-interacting protein 3 (NRIP3)	OTU15GMK	NRIP3_HUMAN	Decreases Expression	[155]
G-protein coupled receptor family C group 5 member C (GPRC5C)	OT45AJT3	GPC5C_HUMAN	Decreases Expression	[155]
PR domain zinc finger protein 8 (PRDM8)	OTRA3265	PRDM8_HUMAN	Increases Expression	[155]
Integral membrane protein 2C (ITM2C)	OTHVMXE3	ITM2C_HUMAN	Decreases Expression	[155]
Rho guanine nucleotide exchange factor 3 (ARHGEF3)	OTHGNC0A	ARHG3_HUMAN	Decreases Expression	[155]
Olfactomedin-like protein 3 (OLFML3)	OTDN45FN	OLFL3_HUMAN	Decreases Expression	[155]
Kinesin-like protein KIF15 (KIF15)	OTJRJEXL	KIF15_HUMAN	Increases Expression	[155]
Serine palmitoyltransferase 3 (SPTLC3)	OTZDX6PT	SPTC3_HUMAN	Decreases Expression	[155]
Transmembrane protein 45A (TMEM45A)	OT54KJG6	TM45A_HUMAN	Decreases Expression	[155]
Host cell factor C1 regulator 1 (HCFC1R1)	OTGDPS5C	HPIP_HUMAN	Decreases Expression	[155]
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2)	OT65C86U	IMPA3_HUMAN	Decreases Expression	[155]
PH and SEC7 domain-containing protein 3 (PSD3)	OTTN9B9O	PSD3_HUMAN	Increases Expression	[155]
G-protein coupled receptor 83 (GPR83)	OT7A2FE8	GPR83_HUMAN	Decreases Expression	[155]
Podocalyxin-like protein 2 (PODXL2)	OTB3PUR8	PDXL2_HUMAN	Increases Expression	[155]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1)	OTY6ZHVA	RGL1_HUMAN	Decreases Expression	[155]
Myoferlin (MYOF)	OTRFC3IJ	MYOF_HUMAN	Decreases Expression	[155]
Low-density lipoprotein receptor-related protein 1B (LRP1B)	OT4YZG2N	LRP1B_HUMAN	Decreases Expression	[155]
LIM and cysteine-rich domains protein 1 (LMCD1)	OT3AWE8O	LMCD1_HUMAN	Decreases Expression	[155]
Protein PALS2 (PALS2)	OTV12NKE	PALS2_HUMAN	Decreases Expression	[155]
Spermatogenesis-associated protein 7 (SPATA7)	OT78G2IH	SPAT7_HUMAN	Increases Expression	[155]
Neurotrimin (NTM)	OTHF0UQU	NTRI_HUMAN	Decreases Expression	[155]
C-type lectin domain family 1 member B (CLEC1B)	OTO38TRG	CLC1B_HUMAN	Decreases Expression	[155]
Dynein axonemal heavy chain 2 (DNAH2)	OT7J5LDI	DYH2_HUMAN	Decreases Expression	[155]
Semaphorin-5B (SEMA5B)	OTUVSKK0	SEM5B_HUMAN	Increases Expression	[155]
Signal-induced proliferation-associated 1-like protein 2 (SIPA1L2)	OT8NJE5D	SI1L2_HUMAN	Decreases Expression	[155]
Protein dispatched homolog 3 (DISP3)	OTEW6RYT	DISP3_HUMAN	Increases Expression	[155]
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9)	OTV3Q0DS	ATS9_HUMAN	Decreases Expression	[155]
Vesicular glutamate transporter 2 (SLC17A6)	OTP1MJGP	VGLU2_HUMAN	Increases Expression	[155]
Beta-1,4-galactosyltransferase 7 (B4GALT7)	OTG5WHRW	B4GT7_HUMAN	Decreases Expression	[155]
Tachykinin-3 (TAC3)	OTOJGM38	TKNK_HUMAN	Decreases Expression	[155]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1)	OTTLJH8W	ATS1_HUMAN	Decreases Expression	[155]
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAIAP2L1)	OTZ71SK9	BI2L1_HUMAN	Decreases Expression	[155]
SERTA domain-containing protein 1 (SERTAD1)	OTBHKZQP	SRTD1_HUMAN	Decreases Expression	[155]
F-box only protein 2 (FBXO2)	OTF3677S	FBX2_HUMAN	Decreases Expression	[155]
Angiopoietin-related protein 2 (ANGPTL2)	OTB6JG41	ANGL2_HUMAN	Decreases Expression	[155]
Microtubule-associated tumor suppressor 1 (MTUS1)	OTBPALMU	MTUS1_HUMAN	Increases Expression	[155]
Y+L amino acid transporter 1 (SLC7A7)	OTYNABBR	YLAT1_HUMAN	Decreases Expression	[155]
Lysosomal thioesterase PPT2 (PPT2)	OTD5VJ9A	PPT2_HUMAN	Decreases Expression	[155]
Protein NDRG2 (NDRG2)	OT5L6KD7	NDRG2_HUMAN	Decreases Expression	[155]
LIM and calponin homology domains-containing protein 1 (LIMCH1)	OTYPC4XA	LIMC1_HUMAN	Increases Expression	[155]
Type 2 lactosamine alpha-2,3-sialyltransferase (ST3GAL6)	OTB17Q43	SIA10_HUMAN	Decreases Expression	[155]
Nuclease EXOG, mitochondrial (EXOG)	OTZAI8L7	EXOG_HUMAN	Decreases Expression	[155]
Netrin-G1 (NTNG1)	OTF48IID	NTNG1_HUMAN	Increases Expression	[155]
Protein SSUH2 homolog (SSUH2)	OTWUBDV0	SSUH2_HUMAN	Increases Expression	[155]
Transmembrane protein 98 (TMEM98)	OTKDUEED	TMM98_HUMAN	Decreases Expression	[155]
Plasmolipin (PLLP)	OTFGCB9U	PLLP_HUMAN	Decreases Expression	[155]
C2 domain-containing protein 2 (C2CD2)	OTL1K0OB	C2CD2_HUMAN	Decreases Expression	[155]
Talin-2 (TLN2)	OT10QQBC	TLN2_HUMAN	Decreases Expression	[155]
Protein mab-21-like 2 (MAB21L2)	OTZM5VMX	MB212_HUMAN	Decreases Expression	[155]
Transient receptor potential cation channel subfamily V member 2 (TRPV2)	OT0A9AVD	TRPV2_HUMAN	Decreases Expression	[155]
Transcription factor SOX-21 (SOX21)	OTNT50CC	SOX21_HUMAN	Increases Expression	[155]
LHFPL tetraspan subfamily member 6 protein (LHFPL6)	OTY6LHJY	LHPL6_HUMAN	Increases Expression	[155]
Stonin-1 (STON1)	OT2HPUAI	STON1_HUMAN	Decreases Expression	[155]
Transcription factor E2F8 (E2F8)	OTQKZGFP	E2F8_HUMAN	Increases Expression	[156]
Thymidine kinase 2, mitochondrial (TK2)	OTS1V4XB	KITM_HUMAN	Decreases Expression	[168]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)	OTA1CPBV	TR10B_HUMAN	Increases Expression	[169]
Protein regulator of cytokinesis 1 (PRC1)	OTHD0XS0	PRC1_HUMAN	Decreases Expression	[12]
PRA1 family protein 3 (ARL6IP5)	OTYZ6BEQ	PRAF3_HUMAN	Increases Expression	[170]
Prothrombin (F2)	OTNFSM49	THRB_HUMAN	Affects Expression	[78]
Plasminogen (PLG)	OTWWIPPY	PLMN_HUMAN	Affects Localization	[171]
Prolactin (PRL)	OTWFQGX7	PRL_HUMAN	Increases Expression	[172]
Tumor necrosis factor (TNF)	OT4IE164	TNFA_HUMAN	Increases Expression	[173]
Thymidine kinase, cytosolic (TK1)	OTY5JFM1	KITH_HUMAN	Decreases Expression	[168]
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	OTBPMIMW	G3P_HUMAN	Decreases Activity	[174]
Interleukin-6 (IL6)	OTUOSCCU	IL6_HUMAN	Increases Expression	[173]
Transcription factor Jun (JUN)	OTCYBO6X	JUN_HUMAN	Increases Expression	[175]
High mobility group protein B1 (HMGB1)	OT4B7CPF	HMGB1_HUMAN	Increases Secretion	[72]
Poly polymerase 1 (PARP1)	OT310QSG	PARP1_HUMAN	Increases Degradation	[176]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Decreases Expression	[175]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Phosphorylation	[174]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[156]
Tumor necrosis factor receptor superfamily member 6 (FAS)	OTP9XG86	TNR6_HUMAN	Increases Expression	[156]
Cyclin-dependent kinases regulatory subunit 2 (CKS2)	OTPTMHIV	CKS2_HUMAN	Decreases Expression	[12]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[156]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Increases Activity	[177]
Importin subunit alpha-1 (KPNA2)	OTU7FOE6	IMA1_HUMAN	Decreases Expression	[12]
Sestrin-3 (SESN3)	OTJRY1Y5	SESN3_HUMAN	Decreases Expression	[156]
Beta-2-microglobulin (B2M)	OTDWN6NX	B2MG_HUMAN	Increases Expression	[178]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (PLCB2)	OTPAHDGO	PLCB2_HUMAN	Affects Localization	[179]
Transcription factor p65 (RELA)	OTUJP9CN	TF65_HUMAN	Decreases Activity	[180]
Apoptosis regulator BAX (BAX)	OTAW0V4V	BAX_HUMAN	Increases Expression	[181]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)	OT2YYI1A	MCL1_HUMAN	Decreases Expression	[182]
Cyclin-dependent kinase 5 activator 1 (CDK5R1)	OTJELWK0	CD5R1_HUMAN	Increases Expression	[156]
Borealin (CDCA8)	OT17D55D	BOREA_HUMAN	Decreases Expression	[12]
Proline/serine-rich coiled-coil protein 1 (PSRC1)	OT7MDJMN	PSRC1_HUMAN	Decreases Expression	[12]
Protein aurora borealis (BORA)	OTV2ZPKP	BORA_HUMAN	Decreases Expression	[12]
Jouberin (AHI1)	OT8K2YWY	AHI1_HUMAN	Increases Expression	[106]
Transient receptor potential cation channel subfamily V member 1 (TRPV1)	OTHHDR03	TRPV1_HUMAN	Affects Localization	[183]
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19)	OTTVT4MB	TNR19_HUMAN	Decreases Expression	[156]
Solute carrier family 12 member 6 (SLC12A6)	OT9CS413	S12A6_HUMAN	Decreases Expression	[156]
Lactosylceramide alpha-2,3-sialyltransferase (ST3GAL5)	OT27CCUF	SIAT9_HUMAN	Decreases Expression	[156]
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1)	OTJQL0I3	HEY1_HUMAN	Decreases Expression	[156]
Interleukin-3 (IL3)	OT0CQ35N	IL3_HUMAN	Increases ADR	[52]
Kynurenine 3-monooxygenase (KMO)	OT3MRMM9	KMO_HUMAN	Increases Response To Substance	[184]
Stathmin-4 (STMN4)	OT7ZUKW6	STMN4_HUMAN	Increases Response To Substance	[184]
Histone-lysine N-methyltransferase 2A (KMT2A)	OT9GLJI6	KMT2A_HUMAN	Increases Response To Substance	[185]
Protein lyl-1 (LYL1)	OTCNOV1M	LYL1_HUMAN	Decreases Response To Substance	[186]
Metalloproteinase inhibitor 3 (TIMP3)	OTDGQAD1	TIMP3_HUMAN	Decreases Response To Substance	[187]
Tumor protein p53-inducible protein 11 (TP53I11)	OTFPDYZU	P5I11_HUMAN	Increases Response To Substance	[184]
Hepatocyte growth factor (HGF)	OTGHUA23	HGF_HUMAN	Increases ADR	[52]
Multidrug resistance-associated protein 1 (ABCC1)	OTGUN89S	MRP1_HUMAN	Affects Response To Substance	[188]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Increases Response To Substance	[189]
14-3-3 protein sigma (SFN)	OTLJCZ1U	1433S_HUMAN	Decreases Response To Substance	[190]
Protein kinase C zeta type (PRKCZ)	OTN2FE42	KPCZ_HUMAN	Decreases Response To Substance	[139]
Calcitonin receptor (CALCR)	OTOVDJ7S	CALCR_HUMAN	Increases Response To Substance	[184]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)	OTOWDUNT	PTEN_HUMAN	Increases Response To Substance	[191]
Glutathione S-transferase Mu 1 (GSTM1)	OTSBF2MO	GSTM1_HUMAN	Affects Response To Substance	[28]
Methylenetetrahydrofolate reductase (MTHFR)	OTUBJSR7	MTHR_HUMAN	Affects Response To Substance	[187]
Deoxycytidine kinase (DCK)	OTW8HLZC	DCK_HUMAN	Decreases Response To Substance	[167]

Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
Ewing sarcoma	DCTGD8J	TC-71	Investigative	[192]

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