Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0JXBK)

Drug Name
DZNep Drug Info
Synonyms 3-deazaneplanocin A
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
73087
CAS Number
CAS 102052-95-9
TTD Drug ID
DM0JXBK

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Adenosylhomocysteinase (AHCY)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ARISTEROMYCIN DMRXB74 N. A. N. A. Terminated [6]
Nicotinamide-Adenine-Dinucleotide DM9LRKB N. A. N. A. Investigative [7]
2-Propanol, Isopropanol DML5O0H Discovery agent N.A. Investigative [8]
Neplanocin A DMXULGK Discovery agent N.A. Investigative [9]
5'-deoxy-5'-ureidoadenosine DM8IQX4 Discovery agent N.A. Investigative [10]
5(E)-(5'-Deoxyadenosin-5'-ylidene)pentanoic acid DM1IGOD Discovery agent N.A. Investigative [11]
5-methylenearisteromycin DMIQ1X3 Discovery agent N.A. Investigative [6]
NORARISTEROMYCIN DMZ9024 Discovery agent N.A. Investigative [12]
D-Eritadenine DM2XT7S N. A. N. A. Investigative [7]
5'-S-ethyl-5'-thioadenosine DM0PQH1 Discovery agent N.A. Investigative [8]
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Drug(s) Affected By Huntingtin-interacting protein 1 (HIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [14]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [15]
Panobinostat DM58WKG Chronic graft versus host disease Approved [4]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [16]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [17]
Ethanol DMDRQZU Chronic pain MG30 Approved [18]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [19]
Arsenic DMTL2Y1 N. A. N. A. Approved [20]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
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Drug(s) Affected By Histone-lysine N-methyltransferase SUV39H1 (SUV39H1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [23]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [25]
Testosterone DM7HUNW Hot flushes GA30 Approved [26]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [26]
Leflunomide DMR8ONJ Arthritis FA20 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
Ethanol DMDRQZU Chronic pain MG30 Approved [29]
Bortezomib DMNO38U Leukemia Approved [30]
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Drug(s) Affected By Histone-lysine N-methyltransferase NSD2 (NSD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Panobinostat DM58WKG Chronic graft versus host disease Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Testosterone DM7HUNW Hot flushes GA30 Approved [26]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [26]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [34]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [35]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [19]
Arsenic DMTL2Y1 N. A. N. A. Approved [20]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [36]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [37]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [38]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [39]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [40]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [41]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Verapamil DMA7PEW Angina pectoris BA40 Approved [42]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [43]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [44]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [45]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [46]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [47]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [48]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [49]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [49]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
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Drug(s) Affected By Glucose-6-phosphate 1-dehydrogenase (G6PD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [36]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [41]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [53]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [54]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [15]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [58]
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Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [59]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [60]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [61]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [62]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [65]
Panobinostat DM58WKG Chronic graft versus host disease Approved [32]
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Drug(s) Affected By Coilin (COIL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [67]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [17]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [19]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [68]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
Urethane DM7NSI0 N. A. N. A. Phase 4 [69]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [4]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [70]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [71]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [72]
Gefitinib DM15F0X Colon adenocarcinoma Approved [73]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [74]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Etretinate DM2CZFA Keratosis ED56 Approved [76]
Prednisone DM2HG4X Acute asthma CA23 Approved [77]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [78]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [79]
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Drug(s) Affected By Hexokinase-2 (HK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Epinephrine DM3KJBC Acute asthma CA23 Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [82]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [83]
Leflunomide DMR8ONJ Arthritis FA20 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [85]
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Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [87]
Gefitinib DM15F0X Colon adenocarcinoma Approved [88]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [89]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [90]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [91]
Methotrexate DM2TEOL Anterior urethra cancer Approved [92]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [93]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [94]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [37]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [95]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Verapamil DMA7PEW Angina pectoris BA40 Approved [42]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [59]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [89]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [74]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Meloxicam DM2AR7L Arthritis FA20 Approved [97]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [78]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [100]
Selenium DM25CGV N. A. N. A. Approved [101]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [102]
Methotrexate DM2TEOL Anterior urethra cancer Approved [103]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [104]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [107]
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Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [44]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [59]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [108]
Methotrexate DM2TEOL Anterior urethra cancer Approved [109]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [112]
Ethacrynic acid DM60QMR Edema MG29 Approved [113]
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Drug(s) Affected By Histone-lysine N-methyltransferase EZH2 (EZH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [3]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [115]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [116]
Testosterone DM7HUNW Hot flushes GA30 Approved [26]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [26]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
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Drug(s) Affected By Transcriptional protein SWT1 (SWT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [19]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [117]
Arsenic DMTL2Y1 N. A. N. A. Approved [20]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [118]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [120]
Urethane DM7NSI0 N. A. N. A. Phase 4 [69]
PEITC DMOMN31 Prostate cancer 2C82.0 Phase 2 [121]
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Drug(s) Affected By Transmembrane protein 87A (TMEM87A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [122]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [4]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [123]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [4]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [19]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [124]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [125]
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Drug(s) Affected By Dapper homolog 3 (DACT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [14]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [127]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [128]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [19]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [5]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [68]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [124]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
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Drug(s) Affected By Fructose-2,6-bisphosphatase TIGAR (TIGAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [79]
Methotrexate DM2TEOL Anterior urethra cancer Approved [103]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Testosterone DM7HUNW Hot flushes GA30 Approved [129]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [130]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [130]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [67]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [130]
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Drug(s) Affected By E3 ubiquitin-protein ligase Jade-2 (JADE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Panobinostat DM58WKG Chronic graft versus host disease Approved [32]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [132]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [4]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [127]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [133]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [4]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [32]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [134]
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Drug(s) Affected By Kelch-like protein 42 (KLHL42)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [34]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [4]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [4]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [133]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [118]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [135]
Urethane DM7NSI0 N. A. N. A. Phase 4 [69]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [4]
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Drug(s) Affected By Two pore channel protein 1 (TPCN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [92]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [25]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [130]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [130]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [130]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [130]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [130]
Arsenic DMTL2Y1 N. A. N. A. Approved [20]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [136]
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Drug(s) Affected By DmX-like protein 1 (DMXL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [137]
Panobinostat DM58WKG Chronic graft versus host disease Approved [4]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [138]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [139]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [19]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [68]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [140]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [141]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [142]
Gefitinib DM15F0X Colon adenocarcinoma Approved [143]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [144]
Selenium DM25CGV N. A. N. A. Approved [145]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [146]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [147]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [148]
Methotrexate DM2TEOL Anterior urethra cancer Approved [92]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adenosylhomocysteinase (AHCY) TTE2KUJ SAHH_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [2]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [2]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [2]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Gene/Protein Processing [3]
Coilin (COIL) OTP4I4DL COIL_HUMAN Gene/Protein Processing [4]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [4]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Gene/Protein Processing [2]
Dapper homolog 3 (DACT3) OTSNQ55G DACT3_HUMAN Gene/Protein Processing [5]
DmX-like protein 1 (DMXL1) OTWVL31L DMXL1_HUMAN Gene/Protein Processing [4]
E3 ubiquitin-protein ligase Jade-2 (JADE2) OTVG2MYF JADE2_HUMAN Gene/Protein Processing [4]

References

1 3-Deazaneplanocin: a new and potent inhibitor of S-adenosylhomocysteine hydrolase and its effects on human promyelocytic leukemia cell line HL-60. Biochem Biophys Res Commun. 1986 Mar 13;135(2):688-94.
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3 Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2. Biochem Pharmacol. 2011 Feb 15;81(4):510-7. doi: 10.1016/j.bcp.2010.11.014. Epub 2010 Nov 27.
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