Details of the Drug-Related molecule(s) Interaction Atlas

CERC-801 Drug Info

D-(+)-Galactose Anhydrous; D-Galactopyranose; D-Galactopyranoside; D-Galactose; D-Galactose (9CI); D-Glucose-2-13C; Echocon; Echovist; Galactopyranose; Galactopyranoside; Galactose; Galactose, D- (8CI); Galactose, pure; Shu 450; Shu 454; Shu-454; brain sugar; cerebrose; dl-Galactose; 10257-28-0; AC1L1LNU; AC1Q28DZ; AI3-18440; CHEBI:4139; D-Gal; DSSTox_CID_3088; DSSTox_GSID_23088; DSSTox_RID_76869; EINECS 233-595-2; Epitope ID:141794; Gal; MLS001335983; MLS001335984; NCGC00159442-02; SCHEMBL38935; SMR000857326

Cross-matching ID

PubChem CID

6036

ChEBI ID

CHEBI:4139

CAS Number

CAS 10257-28-0

TTD Drug ID

DM3SZ7P

INTEDE Drug ID

DR0759

General Information of Drug (ID: DM3SZ7P)

Molecule-Related Drug Atlas

Molecule Type:

DME

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Patented Agent(s)

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Drug(s) Metabolized By Sulfotransferase 1A1 (SULT1A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[9]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[10]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[11]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[12]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[13]
Warfarin	DMJYCVW	Atrial fibrillation	BC81.3	Approved	[14]
Cholic Acid	DM7OKQV	Cholelithiasis	DC11	Approved	[15]
Liothyronine	DM6IR3P	Congenital hypothyroidism		Approved	[16]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[17]
Benzyl alcohol	DMBVYDI	Head and body lice	1G00.0	Approved	[18]
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Drug(s) Metabolized By Glyceraldehyde-3-phosphate dehydrogenase (gap)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AS-12141	DMIV1WR	N. A.	N. A.	Phase 3	[3]
D-mannose	DMT6X03	Discovery agent	N.A.	Investigative	[3]
NA-alpha-D-glucosamine	DMRKIYB	N. A.	N. A.	Investigative	[3]
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Drug(s) Affected By Copper transport protein ATOX1 (ATOX1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[19]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[20]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[21]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[22]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[23]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[24]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[19]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[25]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[26]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[27]
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Drug(s) Affected By Glutathione synthetase (GSS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[28]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[29]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[30]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[31]
Ursodeoxycholic acid	DMCUT21	Cholelithiasis	DC11	Approved	[32]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[22]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[33]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[23]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[24]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[34]
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Drug(s) Affected By Aldehyde oxidase (AOX1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[35]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[36]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[37]
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[38]
Nefazodone	DM4ZS8M	Major depressive disorder	6A70.3	Approved	[39]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[40]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[20]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Dasatinib	DMJV2EK	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[42]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[43]
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Drug(s) Affected By Dynamin-1-like protein (DNM1L)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[44]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[45]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[46]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[47]
Efavirenz	DMC0GSJ	Human immunodeficiency virus infection	1C62	Approved	[48]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[22]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[49]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[50]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[44]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[51]
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Drug(s) Affected By Mitofusin-2 (MFN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[29]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[52]
Efavirenz	DMC0GSJ	Human immunodeficiency virus infection	1C62	Approved	[48]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[53]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[22]
Melatonin	DMKWFBT	Depression	6A70-6A7Z	Approved	[54]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[55]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[56]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[25]
Resveratrol	DM3RWXL	Giant cell arteritis	4A44.2	Phase 3	[57]
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Drug(s) Affected By Ubiquitin-like modifier-activating enzyme ATG7 (ATG7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[58]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[59]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[60]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[29]
Nefazodone	DM4ZS8M	Major depressive disorder	6A70.3	Approved	[39]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[61]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[62]
Promethazine	DM6I5GR	Hyperemesis gravidarum		Approved	[63]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[39]
Cantharidin	DMBP5N3	Molluscum contagiosum infection	1E76	Approved	[64]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[65]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[66]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[67]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[68]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[69]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[70]
Floxuridine	DM04LR2	Colorectal cancer	2B91.Z	Approved	[71]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[72]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[73]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[74]
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Drug(s) Affected By Interleukin-6 (IL6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[38]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[75]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[76]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[77]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[78]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[79]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[80]
Imiquimod	DM1TMA3	Alopecia areata	ED70.2	Approved	[81]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[82]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[38]
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Drug(s) Affected By Interleukin-8 (CXCL8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[83]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[84]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[85]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[77]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[86]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[79]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[87]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[88]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[89]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[87]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sevoflurane	DMC9O43	Anaesthesia	9A78.6	Approved	[90]
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[91]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[92]
Gemcitabine	DMSE3I7	Anterior urethra cancer		Approved	[93]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[94]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[76]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[95]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[96]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[97]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[98]
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Drug(s) Affected By Endoplasmic reticulum chaperone BiP (HSPA5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[99]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[100]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[101]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[102]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[103]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[104]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[105]
Naloxone	DM3FXMA	Narcotic depression	6A7Z	Approved	[106]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[36]
Furazolidone	DM3P6V7	Diarrhea	ME05.1	Approved	[107]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[108]
Triacetin	DM0AEPG	Onychomycosis	EE12.1	Approved	[109]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[110]
Bepridil	DM0RKS4	Chronic/stable angina	BA40.1	Approved	[111]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[100]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[112]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[103]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[113]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[114]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[36]
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Drug(s) Affected By Caspase-3 (CASP3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sevoflurane	DMC9O43	Anaesthesia	9A78.6	Approved	[115]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[116]
Lovastatin	DM9OZWQ	Arteriosclerosis	BD40	Approved	[117]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[69]
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[118]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[119]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[120]
Mannitol	DMSCDY9	Bronchiectasis	CA24	Approved	[121]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[122]
Aprepitant	DM053KT	Depression	6A70-6A7Z	Approved	[123]
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Drug(s) Affected By Heat shock factor protein 1 (HSF1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[124]
SPI-1005	DM6XFHS	Reperfusion injury	ND56.Z	Approved	[125]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[125]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[126]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[127]
Ceftazidime	DM41GRA	Bacteremia	1A73	Approved	[125]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[29]
Chlorpheniramine	DM5URA2	Allergic rhinitis	CA08.0	Approved	[125]
Ethacrynic acid	DM60QMR	Edema	MG29	Approved	[125]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[125]
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Drug(s) Affected By Transcription factor p65 (RELA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[128]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[98]
Selenium	DM25CGV	N. A.	N. A.	Approved	[26]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[129]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[130]
Deoxycholic acid	DM3GYAL	Subcutaneous fat disorder	EF02	Approved	[131]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[36]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[132]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[133]
Glucosamine	DM4ZLFD	Osteoarthritis	FA00-FA05	Approved	[134]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sevoflurane	DMC9O43	Anaesthesia	9A78.6	Approved	[90]
Aprepitant	DM053KT	Depression	6A70-6A7Z	Approved	[123]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[76]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[95]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[135]
Leuprorelin acetate	DM15HAT	Prostate cancer	2C82.0	Approved	[136]
Talazoparib	DM1KS78	Breast cancer	2C60-2C65	Approved	[137]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[138]
Meloxicam	DM2AR7L	Arthritis	FA20	Approved	[139]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[140]
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Drug(s) Affected By Sequestosome-1 (SQSTM1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[141]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[142]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[143]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[144]
Trametinib	DM2JGQ3	Melanoma	2C30	Approved	[145]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[146]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[147]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[36]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[148]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[149]
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Drug(s) Affected By NAD-dependent protein deacetylase sirtuin-1 (SIRT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[150]
Selenium	DM25CGV	N. A.	N. A.	Approved	[26]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[146]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[151]
Isoniazid	DM5JVS3	Latent tuberculosis infection		Approved	[152]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[153]
Prasterone	DM67VKL	Chronic obstructive pulmonary disease	CA22	Approved	[154]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[155]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[156]
Olaparib	DM8QB1D	Ovarian cancer	2C73	Approved	[157]
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Drug(s) Affected By Sodium/glucose cotransporter 1 (SLC5A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[158]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[159]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[160]
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[161]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[25]
Triclosan	DMZUR4N	Malaria	1F40-1F45	Approved	[162]
3,4-Dihydroxycinnamic Acid	DMVZL26	Thrombocytopenia	3B64	Phase 4	[163]
Resveratrol	DM3RWXL	Giant cell arteritis	4A44.2	Phase 3	[164]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[165]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[166]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-deoxyglucose	DMIAHVU	Solid tumour/cancer	2A00-2F9Z	Approved	[167]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[158]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[168]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[169]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[168]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[35]
Thioridazine	DM35M8J	Schizophrenia	6A20	Approved	[168]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[36]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[168]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[170]
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Drug(s) Affected By NADH-ubiquinone oxidoreductase chain 4 (ND4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[171]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[172]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[173]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[53]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[22]
Cholecalciferol	DMGU74E	Adult acute monocytic leukemia		Approved	[174]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[175]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[176]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[25]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[177]
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⏷ Show the Full List of 10 Drug(s)

Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-deoxyglucose	DMIAHVU	Solid tumour/cancer	2A00-2F9Z	Approved	[167]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[178]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[35]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[36]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[179]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[180]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[181]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[20]
Atorvastatin	DMF28YC	Acute coronary syndrome	BA41	Approved	[182]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
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⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Sulfotransferase 1A1 (SULT1A1)	DEYWLRK	ST1A1_HUMAN	Substrate	[1]
Galactose kinase (GALK1)	DE3OP9S	GALK1_HUMAN	Substrate	[2]
Glyceraldehyde-3-phosphate dehydrogenase (gap)	DEVSIE6	A0A3A9YGB0_LACAI	Substrate	[3]
L-arabinose isomerase (araA)	DETP28W	ARAA_LACSS	Substrate	[4]
L-arabinose isomerase (araA)	DEU37LK	C0C0X3_9FIRM	Substrate	[5]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Aldehyde oxidase (AOX1)	OT2FZP6H	AOXA_HUMAN	Gene/Protein Processing	[6]
Apoptosis regulator BAX (BAX)	OTAW0V4V	BAX_HUMAN	Gene/Protein Processing	[7]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Gene/Protein Processing	[7]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Protein Interaction/Cellular Processes	[7]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Gene/Protein Processing	[7]
Copper transport protein ATOX1 (ATOX1)	OT05LF59	ATOX1_HUMAN	Gene/Protein Processing	[6]
DNA damage-inducible transcript 3 protein (DDIT3)	OTI8YKKE	DDIT3_HUMAN	Gene/Protein Processing	[7]
Dynamin-1-like protein (DNM1L)	OTXK1Q1G	DNM1L_HUMAN	Gene/Protein Processing	[8]
Endoplasmic reticulum chaperone BiP (HSPA5)	OTFUIRAO	BIP_HUMAN	Gene/Protein Processing	[7]
Glutathione synthetase (GSS)	OTVSBEIW	GSHB_HUMAN	Gene/Protein Processing	[6]

------------------------------------------------------------------------------------

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