Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPS2B1)

Drug Name
Hydroxydimethylarsine Oxide Drug Info
Synonyms
Cacodylic acid; cacodylic acid; Dimethylarsinic acid; 75-60-5; Hydroxydimethylarsine oxide; Chexmate; Silvisar; Phytar; Arsan; Erase; DIMETHYLARSENIC ACID; Silvisar 510; Arsinic acid, dimethyl-; Phytar 560; Ansar 138; Sylvicor; Moncide; Dilic; Rad-e-cate 35; Agent Blue; Acide cacodylique; Alkargen; Phytar 138; Acide dimethylarsinique; Cotton aide HC; Kyselina kakodylova; RCRA waste number U136; Phytar 600; Caswell No 133; Arsine oxide, hydroxydimethyl-; Ansar; UNII-AJ2HL7EU8K; Acide cacodylique [French]; Kyselina kakodylova [Czech]
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2513
ChEBI ID
CHEBI:48765
CAS Number
CAS 75-60-5
TTD Drug ID
DMPS2B1

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Approved Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Nitric-oxide synthase endothelial (NOS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tilarginine acetate DMZBGI8 Myocardial infarction BA41-BA43 Phase 3 [8]
L-NAME DM01SR6 Hypertension BA00-BA04 Phase 2 [9]
ACCLAIM DM0FGDO Angina pectoris BA40 Phase 2 [10]
VAS-203 DMKU93J Brain injury NA07.Z Phase 2 [11]
MTR105 DMT0K4F Hypotension BA20-BA21 Phase 2 [12]
Autologous cell based gene therapy DMQA1VT Pulmonary hypertension BB01 Phase 1 [13]
L-NIL DM6Y49D N. A. N. A. Terminated [14]
Acetate Ion DMD08RH Discovery agent N.A. Investigative [1]
2-Methyl-2,4-Pentanediol DMD45CU Discovery agent N.A. Investigative [1]
Heme DMGC287 Discovery agent N.A. Investigative [15]
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Drug(s) Targeting Aldose reductase (AKR1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Epalrestat DM5OGK0 Diabetic neuropathy 8C0Z Approved [16]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [17]
Fidarestat DMZL1I8 Diabetic complication 5A2Y Phase 3 [18]
Ranirestat DMD5QRS Diabetic neuropathy 8C0Z Phase 3 [19]
CONTIGOSIDE B DMX9V8K Thrombosis DB61-GB90 Phase 2/3 [20]
BNV-222 DMYFQJL Diabetic neuropathy 8C0Z Phase 2/3 [19]
BNV-222 DMYFQJL Diabetic neuropathy 8C0Z Phase 2/3 [21]
LIDORESTAT DMA0RI9 Diabetic complication 5A2Y Phase 2 [22]
QR-333 DMKVIWM Diabetic neuropathy 8C0Z Phase 2 [23]
ADMVA DM819CO Diabetic complication 5A2Y Phase 2 [19]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [24]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [25]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [26]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [27]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [28]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [29]
Ethacrynic acid DM60QMR Edema MG29 Approved [30]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [31]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [32]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [33]
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Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [34]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [37]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [38]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [39]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [40]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [41]
Quercetin DM3NC4M Obesity 5B81 Approved [42]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [43]
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Drug(s) Affected By Glutathione S-transferase A4 (GSTA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [44]
Quercetin DM3NC4M Obesity 5B81 Approved [45]
Leflunomide DMR8ONJ Arthritis FA20 Approved [46]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Ethanol DMDRQZU Chronic pain MG30 Approved [49]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [50]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [51]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [52]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [44]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [53]
Gefitinib DM15F0X Colon adenocarcinoma Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [56]
Etretinate DM2CZFA Keratosis ED56 Approved [57]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [58]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [59]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [60]
Quercetin DM3NC4M Obesity 5B81 Approved [61]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [62]
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Drug(s) Affected By Carbonic anhydrase 12 (CA12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetazolamide DM1AF5U Absence epilepsy Approved [63]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [66]
Panobinostat DM58WKG Chronic graft versus host disease Approved [67]
Estrone DM5T6US Acne vulgaris ED80 Approved [64]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [68]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
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Drug(s) Affected By Protransforming growth factor alpha (TGFA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [70]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Methotrexate DM2TEOL Anterior urethra cancer Approved [71]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [72]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [74]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [75]
Leflunomide DMR8ONJ Arthritis FA20 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [50]
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Drug(s) Affected By Lipoprotein lipase (LPL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [76]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [78]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [80]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [81]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [82]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [81]
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Drug(s) Affected By Bone morphogenetic protein 1 (BMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [86]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [89]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [90]
Seocalcitol DMKL9QO Rickets 5B57 Phase 3 [91]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [92]
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Drug(s) Affected By Matrix metalloproteinase-9 (MMP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Gefitinib DM15F0X Colon adenocarcinoma Approved [94]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Selenium DM25CGV N. A. N. A. Approved [95]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [96]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [97]
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [99]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [100]
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Drug(s) Affected By Platelet glycoprotein 4 (CD36)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [103]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [104]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [105]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [108]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [109]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [110]
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Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [111]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [112]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [114]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [58]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [115]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [116]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [117]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [118]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [119]
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Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [111]
Gefitinib DM15F0X Colon adenocarcinoma Approved [121]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [122]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [58]
Methotrexate DM2TEOL Anterior urethra cancer Approved [123]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [125]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [126]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [127]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [128]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [130]
Epinephrine DM3KJBC Acute asthma CA23 Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [132]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [133]
Fructose DM43AN2 Vomiting MD90 Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [135]
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Drug(s) Affected By Macrosialin (CD68)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [103]
Testosterone DM7HUNW Hot flushes GA30 Approved [139]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [139]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [140]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [140]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [141]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [142]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [111]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [112]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [101]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [143]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [144]
Methotrexate DM2TEOL Anterior urethra cancer Approved [145]
Quercetin DM3NC4M Obesity 5B81 Approved [45]
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Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [146]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [147]
Quercetin DM3NC4M Obesity 5B81 Approved [148]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [150]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [151]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [133]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [152]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [153]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [156]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [157]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [158]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [159]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [160]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [161]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [162]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [163]
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Drug(s) Affected By Caspase-2 (CASP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [164]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Methotrexate DM2TEOL Anterior urethra cancer Approved [71]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [166]
Quercetin DM3NC4M Obesity 5B81 Approved [167]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [168]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [169]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [170]
Leflunomide DMR8ONJ Arthritis FA20 Approved [46]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [171]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Prednisone DM2HG4X Acute asthma CA23 Approved [173]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [174]
Quercetin DM3NC4M Obesity 5B81 Approved [175]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [176]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [177]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [178]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
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Drug(s) Affected By Caveolin-2 (CAV2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [181]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [182]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [183]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [184]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [50]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [185]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [186]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [187]
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Drug(s) Affected By Pro-neuregulin-1, membrane-bound isoform (NRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [172]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [188]
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [189]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [124]
Panobinostat DM58WKG Chronic graft versus host disease Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [56]
Selenium DM25CGV N. A. N. A. Approved [114]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [193]
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [194]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [175]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [29]
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Drug(s) Affected By Protocadherin-1 (PCDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [196]
Testosterone DM7HUNW Hot flushes GA30 Approved [139]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [139]
Leflunomide DMR8ONJ Arthritis FA20 Approved [46]
Ethanol DMDRQZU Chronic pain MG30 Approved [49]
Epanova DMHEAGL Hypertriglyceridemia 5C80.1 Approved [197]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [198]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [199]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [89]
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Drug(s) Affected By Interleukin-24 (IL24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [200]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [201]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [202]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [201]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [201]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [203]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [189]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [204]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [201]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [204]
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Drug(s) Affected By Interferon regulatory factor 5 (IRF5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Methotrexate DM2TEOL Anterior urethra cancer Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [51]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [199]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [205]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [65]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [206]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [207]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [205]
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Drug(s) Affected By Rho GTPase-activating protein 21 (ARHGAP21)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [50]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [51]
Arsenic DMTL2Y1 N. A. N. A. Approved [210]
Urethane DM7NSI0 N. A. N. A. Phase 4 [211]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [212]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [213]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 15 member 4 (SLC15A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [214]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [51]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [65]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [215]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [188]
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Drug(s) Affected By Mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [216]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [44]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [44]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [217]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [218]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [219]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [220]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arsenite methyltransferase (AS3MT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [221]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [222]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [223]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [224]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [225]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [51]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [224]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleotide sugar transporter SLC35D1 (SLC35D1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [114]
Quercetin DM3NC4M Obesity 5B81 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [103]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [226]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Testosterone enanthate DMB6871 N. A. N. A. Approved [227]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [51]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [199]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutaminase liver isoform, mitochondrial (GLS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [45]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [124]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [51]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [199]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [229]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [47]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [35]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [230]
Folic Acid DMEMBJC Colorectal carcinoma Approved [231]
Methotrexate DM2TEOL Anterior urethra cancer Approved [232]
Quercetin DM3NC4M Obesity 5B81 Approved [233]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [234]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [235]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [236]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [237]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [238]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier organic anion transporter family member 1B1 (SLCO1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Enalapril DMNFUZR Congestive heart failure BD10 Approved [239]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [240]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [241]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [242]
Methotrexate DM2TEOL Anterior urethra cancer Approved [243]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [244]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [245]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [245]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [246]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [247]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 4 (ABCC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [232]
Quercetin DM3NC4M Obesity 5B81 Approved [248]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [249]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [250]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [117]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [251]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [252]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [253]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione S-transferase theta-1 (GSTT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [254]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [255]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [48]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [256]
Arsenic DMTL2Y1 N. A. N. A. Approved [210]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [229]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [257]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-6 (CASP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [199]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Methotrexate DM2TEOL Anterior urethra cancer Approved [123]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [259]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [260]
Quercetin DM3NC4M Obesity 5B81 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [261]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [262]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [263]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aldose reductase (AKR1B1) TTFBNVI ALDR_HUMAN Inhibitor [1]
Nitric-oxide synthase endothelial (NOS3) TTCM4B3 NOS3_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Arsenite methyltransferase (AS3MT) OTNLWD0N AS3MT_HUMAN Gene/Protein Processing [2]
ATP-binding cassette sub-family C member 4 (ABCC4) OTO27PAL MRP4_HUMAN Regulation of Drug Effects [3]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [4]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [5]
Bone morphogenetic protein 1 (BMP1) OTRFFAL4 BMP1_HUMAN Gene/Protein Processing [5]
Carbonic anhydrase 12 (CA12) OT6WNFU8 CAH12_HUMAN Gene/Protein Processing [5]
Caspase-2 (CASP2) OTUDYSPP CASP2_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [6]
Caspase-6 (CASP6) OTXLD3EC CASP6_HUMAN Drug Response [7]
Caveolin-2 (CAV2) OT1FGRQX CAV2_HUMAN Gene/Protein Processing [5]

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