General Information of Drug (ID: DMX9K8F)

Drug Name
Carbachol Drug Info
Synonyms
Carbach; Carbacholin; Carbacholine; Carbacholinum; Carbacholum; Carbacol; Carbacolina; Carbacolo; Carbamiotin; Carbamoylcholine; Carbastat; Carbochol; Carbocholin; Carbocholine; Carbyl; Carcholin; Coletyl; Doryl; Jestryl; Karbachol; Lentin; Lentine; Miostat; Moryl; Rilentol; Vasoperif; CARBACHOL CHLORIDE; Carbachol hydrochloride; Carbacholine chloride; Carbacholini chloridum; Carbacholinium chloratum; Carbacholum chloratum; Carbacolo [DCIT]; Carbaminocholine chloride; Carbaminoylcholine chloride; Carbamoylcholine chloride; Carbamylcholine chloride; Choline carbamate chloride; Choline chloride carbamate; Choline chlorine carbamate; Isopto Carbachol; Karbachol [Czech]; Karbamoylcholin chlorid; Karbamoylcholin chlorid [Czech]; Lentine [French]; Mistura C; C 4382; TL 457; C-1770; Carbacholum [INN-Latin]; Carbacol [INN-Spanish]; Carbamic acid, ester with choline chloride; Carbamoylcholine-hydrochloride; Carbastat (TN); Carboptic (TN); Choline chloride, carbamate; Doryl (VAN); Doryl (pharmaceutical); Gamma-Carbamoyl choline chloride; Isopto Carbachol (TN); Miostat (TN); Carbachol [INN:BAN:JAN]; Choline, chloride carbamate(ester); Choline, chloride, carbamate; P. V. Carbachol; Carbachol (JAN/USP/INN); Choline, chloride, carbamate, hydrochloride; Ethanaminium, 2-(aminocarbonyl)oxy-N,N,N-trimethyl-, chloride; Ethanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride; Ethanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride; Ethanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride (1:1); (2-Carbamoyloxy-ethyl)-trimethyl-ammonium; (2-Carbamoyloxy-ethyl)-trimethyl-ammonium(Carbachol); (2-Carbamoyloxyethyl)trimethylammonium chloride; (2-Hydroxyethyl)trimethyl ammonium chloride carbamate; (2-Hydroxyethyl)trimethylammonium chloride carbamate; (carbachol)(2-Carbamoyloxy-ethyl)-trimethyl-ammonium; 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium chloride; 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminum chloride; 2-(carbamoyloxy)-N,N,N-trimethylethanaminium chloride; 2-[(aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride; 2-carbamoyloxyethyl(trimethyl)azanium chloride
Indication
Disease Entry ICD 11 Status REF
Glaucoma/ocular hypertension 9C61 Approved [1]
Therapeutic Class
Cardiotonic Agents
Cross-matching ID
PubChem CID
5831
ChEBI ID
CHEBI:3385
CAS Number
CAS 51-83-2
TTD Drug ID
DMX9K8F
ACDINA Drug ID
D00912

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rocuronium DMY9BMK Muscle spasm MB47.3 Approved [11]
Tubocurarine DMBZIVP Anaesthesia 9A78.6 Approved [11]
Cisatracurium DMUZPJ5 Muscle spasm MB47.3 Approved [11]
Vecuronium DMP0UK2 Spasm MB47.3 Approved [11]
Levallorphan DMCOLUP Narcotic depression 6A7Z Approved [2]
Mivacurium DM473VD Anaesthesia 9A78.6 Approved [11]
Pipecuronium DM5F84A Spasm MB47.3 Approved [2]
CYTISINE DMUF0BJ Tobacco dependence 6C4A.2 Phase 3 [12]
CHOLINE DM5D9YK Insomnia 7A00-7A0Z Investigative [13]
[125I]epibatidine DMZWQH3 Discovery agent N.A. Investigative [14]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylscopolamine DM5VWOB Peptic ulcer DA61 Approved [9]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [15]
Panobinostat DM58WKG Chronic graft versus host disease Approved [16]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [17]
Testosterone DM7HUNW Hot flushes GA30 Approved [18]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [18]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [19]
Acetylcholine DMDF79Z Cataract 9B10 Approved [20]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [20]
Arsenic DMTL2Y1 N. A. N. A. Approved [21]
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Drug(s) Affected By Aquaporin-5 (AQP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [23]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [24]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [26]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [27]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [28]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [29]
Milchsaure DM462BT Pruritus EC90 Investigative [30]
cordycepin DM72Y01 Discovery agent N.A. Investigative [22]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Pirenzepine DMP6M1N Peptic ulcer DA61 Approved [31]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [5]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [32]
Acetylcholine DMDF79Z Cataract 9B10 Approved [8]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [20]
Clozapine DMFC71L Schizophrenia 6A20 Approved [33]
Olanzapine DMPFN6Y Bipolar depression Approved [34]
Gallamine Triethiodide DMPO0MS Stabilize muscle contraction FB3Z Approved [35]
Methylscopolamine DM5VWOB Peptic ulcer DA61 Approved [9]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [36]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [38]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [40]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [41]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [42]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [38]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [43]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [44]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [45]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [46]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [48]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [49]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [50]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [51]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [52]
Gefitinib DM15F0X Colon adenocarcinoma Approved [53]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [56]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [47]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [57]
Paclitaxel DMLB81S Breast carcinoma Approved [58]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [59]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [46]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [5]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [49]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [50]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [60]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Acetylcholine DMDF79Z Cataract 9B10 Approved [61]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [62]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [63]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [64]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [65]
Cotinine DMCEZ1B Insecticide N.A. Approved [61]
Urethane DM7NSI0 N. A. N. A. Phase 4 [66]
GTS-21 DMEN5KA Parkinson disease 8A00.0 Phase 2 [61]
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Drug(s) Affected By Lysozyme C (LYZ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [70]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [73]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [75]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [76]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [77]
Arsenic DMTL2Y1 N. A. N. A. Approved [21]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [78]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [79]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [64]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [80]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Panobinostat DM58WKG Chronic graft versus host disease Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [19]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [82]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [64]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [83]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [84]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [28]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [85]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [86]
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Drug(s) Affected By Acetylcholinesterase (ACHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetylcholine DMDF79Z Cataract 9B10 Approved [87]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [88]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [89]
Methotrexate DM2TEOL Anterior urethra cancer Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [89]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [92]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [93]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [94]
Testosterone DM7HUNW Hot flushes GA30 Approved [75]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
ALCURONIUM DM2U4XQ Anaesthesia 9A78.6 Approved [95]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Acetylcholine DMDF79Z Cataract 9B10 Approved [96]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [95]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [62]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [97]
Methylscopolamine DM5VWOB Peptic ulcer DA61 Approved [9]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [28]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [85]
brucine DM50RUD Discovery agent N.A. Investigative [95]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [98]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [99]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [101]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [104]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [105]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [106]
Nicotinamide DMUPE07 Acne vulgaris ED80 Approved [100]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [107]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [108]
Verapamil DMA7PEW Angina pectoris BA40 Approved [109]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [110]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [109]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [112]
Methotrexate DM2TEOL Anterior urethra cancer Approved [113]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [114]
Quercetin DM3NC4M Obesity 5B81 Approved [115]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylscopolamine DM5VWOB Peptic ulcer DA61 Approved [116]
Gallamine Triethiodide DMPO0MS Stabilize muscle contraction FB3Z Approved [116]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [108]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [15]
Acetylcholine DMDF79Z Cataract 9B10 Approved [96]
Omadacycline DMR2J95 Acute bacterial skin infection 1C41 Approved [117]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [64]
Bardoxolone methyl DMODA2X Mixed connective tissue disease 4A43.3 Phase 3 [118]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [28]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [85]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrochlorothiazide DMUSZHD Chronic heart failure BD1Z Approved [5]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [119]
Quinidine DMLPICK N. A. N. A. Approved [120]
Verapamil DMA7PEW Angina pectoris BA40 Approved [121]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [122]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [122]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [123]
Propranolol DM79NTF Angina pectoris BA40 Approved [124]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [125]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [126]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [122]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neuronal acetylcholine receptor alpha-2 (CHRNA2) TTF4E0J ACHA2_HUMAN Antagonist [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Acetylcholinesterase (ACHE) OT2H8HG6 ACES_HUMAN Biotransformations [3]
Aquaporin-5 (AQP5) OT77GBY8 AQP5_HUMAN Protein Interaction/Cellular Processes [4]
Cytochrome c oxidase subunit 1 (COX1) OTG3O9BN COX1_HUMAN Drug Response [5]
Lysozyme C (LYZ) OTD7H0G6 LYSC_HUMAN Protein Interaction/Cellular Processes [6]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Gene/Protein Processing [7]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Gene/Protein Processing [7]
Muscarinic acetylcholine receptor M1 (CHRM1) OTKW3E6B ACM1_HUMAN Gene/Protein Processing [8]
Muscarinic acetylcholine receptor M2 (CHRM2) OTUMZ2WR ACM2_HUMAN Drug Response [9]
Muscarinic acetylcholine receptor M3 (CHRM3) OTKSD095 ACM3_HUMAN Gene/Protein Processing [10]
Muscarinic acetylcholine receptor M4 (CHRM4) OTF0F0FF ACM4_HUMAN Drug Response [9]

References

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27 Comparative Analysis of Transcriptomic Changes including mRNA and microRNA Expression Induced by the Xenoestrogens Zearalenone and Bisphenol A in Human Ovarian Cells. Toxins (Basel). 2023 Feb 9;15(2):140. doi: 10.3390/toxins15020140.
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38 Differential effects of statins on relevant functions of human monocyte-derived dendritic cells. J Leukoc Biol. 2006 Mar;79(3):529-38. doi: 10.1189/jlb.0205064. Epub 2005 Dec 30.
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