Details of the Drug

General Information of Drug (ID: DMITSEH)

Drug Name
Isoetharine
Synonyms
Bronkosol; Dilabron; Etyprenaline; Etyprenalinum; Isoetarin; Isoetarina; Isoetarine; Isoetarinum; Neoisuprel; Isoetharine Hcl; Win 3406; Bronkometer (TN); Bronkosol (TN); Dey-Lute Isoetharine; Isoetarina [INN-Spanish]; Isoetarine (INN); Isoetarinum [INN-Latin]; Isoetharine (USP); Isoetharine HCl S/F; Isoetharine [USAN:BAN]; 3,4-Dihydroxy-alpha-(1-(isopropylamino)propyl)benzyl alcohol; 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Approved [1]
Therapeutic Class
Bronchodilator Agents
Affected Organisms
Humans and other mammals
ATC Code
R03AC07: Isoetharine
R03AC: Selective beta-2-adrenoreceptor agonists
R03A: ADRENERGICS, INHALANTS
R03: DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R: RESPIRATORY SYSTEM
R03CC06: Isoetharine
R03CC: Selective beta-2-adrenoreceptor agonists
R03C: ADRENERGICS FOR SYSTEMIC USE
R03: DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R: RESPIRATORY SYSTEM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 239.31
Logarithm of the Partition Coefficient (xlogp) 1.7
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C13H21NO3
IUPAC Name
4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol
Canonical SMILES
CCC(C(C1=CC(=C(C=C1)O)O)O)NC(C)C
InChI
InChI=1S/C13H21NO3/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9/h5-8,10,13-17H,4H2,1-3H3
InChIKey
HUYWAWARQUIQLE-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
3762
ChEBI ID
CHEBI:6005
CAS Number
530-08-5
UNII
YV0SN3276Q
DrugBank ID
DB00221
TTD ID
D08HUC

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor beta-2 (ADRB2) TT2CJVK ADRB2_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Asthma
ICD Disease Classification CA23
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Adrenergic receptor beta-2 (ADRB2) DTT ADRB2 4.88E-01 -0.05 -0.12
Adrenergic receptor beta-2 (ADRB2) DTT ADRB2 7.10E-01 0.06 0.09
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Same Disease as Isoetharine
DDI Drug Name DDI Drug ID Severity Mechanism Disease REF
Budesonide DMJIBAW Minor Increased risk of hypokalemia by the combination of Isoetharine and Budesonide. Asthma [CA23] [4]
Coadministration of a Drug Treating the Disease Different from Isoetharine (Comorbidity)
DDI Drug Name DDI Drug ID Severity Mechanism Comorbidity REF
Methylene blue DMJAPE7 Moderate Additive hypertensive effects by the combination of Isoetharine and Methylene blue. Acquired methaemoglobinaemia [3A93] [5]
Ivosidenib DM8S6T7 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Ivosidenib. Acute myeloid leukaemia [2A60] [6]
Midostaurin DMI6E0R Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Midostaurin. Acute myeloid leukaemia [2A60] [6]
Idarubicin DMM0XGL Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Idarubicin. Acute myeloid leukaemia [2A60] [6]
Daunorubicin DMQUSBT Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Daunorubicin. Acute myeloid leukaemia [2A60] [6]
Arn-509 DMT81LZ Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Arn-509. Acute myeloid leukaemia [2A60] [6]
Gilteritinib DMTI0ZO Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Gilteritinib. Acute myeloid leukaemia [2A60] [6]
Oliceridine DM6MDCF Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Oliceridine. Acute pain [MG31] [7]
Ranolazine DM0C9IL Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Ranolazine. Angina pectoris [BA40] [6]
Ivabradine DM0L594 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Ivabradine. Angina pectoris [BA40] [6]
Dronedarone DMA8FS5 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Dronedarone. Angina pectoris [BA40] [6]
Hydroxyzine DMF8Y74 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Hydroxyzine. Anxiety disorder [6B00-6B0Z] [6]
Cilostazol DMZMSCT Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Cilostazol. Arterial occlusive disease [BD40] [6]
Voriconazole DMAOL2S Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Voriconazole. Aspergillosis [1F20] [6]
Posaconazole DMUL5EW Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Posaconazole. Aspergillosis [1F20] [6]
Lisdexamfetamine DM6W8V5 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Lisdexamfetamine. Attention deficit hyperactivity disorder [6A05] [6]
Droxidopa DM5YF4M Moderate Additive hypertensive effects by the combination of Isoetharine and Droxidopa. Autonomic nervous system disorder [8D87] [8]
Ofloxacin DM0VQN3 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Ofloxacin. Bacterial infection [1A00-1C4Z] [6]
Ciprofloxacin XR DM2NLS9 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Ciprofloxacin XR. Bacterial infection [1A00-1C4Z] [6]
Clarithromycin DM4M1SG Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Clarithromycin. Bacterial infection [1A00-1C4Z] [6]
Linezolid DMGFPU2 Moderate Additive hypertensive effects by the combination of Isoetharine and Linezolid. Bacterial infection [1A00-1C4Z] [5]
Gemifloxacin DMHT34O Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Gemifloxacin. Bacterial infection [1A00-1C4Z] [6]
Norfloxacin DMIZ6W2 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Norfloxacin. Bacterial infection [1A00-1C4Z] [7]
Levofloxacin DMS60RB Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Levofloxacin. Bacterial infection [1A00-1C4Z] [6]
Telithromycin DMZ4P3A Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Telithromycin. Bacterial infection [1A00-1C4Z] [7]
Retigabine DMGNYIH Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Retigabine. Behcet disease [4A62] [7]
Eribulin DM1DX4Q Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Eribulin. Breast cancer [2C60-2C6Y] [6]
Lapatinib DM3BH1Y Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Lapatinib. Breast cancer [2C60-2C6Y] [6]
Tamoxifen DMLB0EZ Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Tamoxifen. Breast cancer [2C60-2C6Y] [6]
Toremifene DMQYUWG Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Toremifene. Breast cancer [2C60-2C6Y] [6]
Bosutinib DMTI8YE Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Bosutinib. Breast cancer [2C60-2C6Y] [6]
Corticotropin DMP9TWZ Minor Increased risk of hypokalemia by the combination of Isoetharine and Corticotropin. Chronic kidney disease [GB61] [4]
PF-04449913 DMSB068 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and PF-04449913. Chronic myelomonocytic leukaemia [2A40] [6]
Levomilnacipran DMV26S8 Moderate Increased risk of rapid heart rate by the combination of Isoetharine and Levomilnacipran. Chronic pain [MG30] [9]
Oxaliplatin DMQNWRD Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Oxaliplatin. Colorectal cancer [2B91] [6]
Halothane DM80OZ5 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Halothane. Corneal disease [9A76-9A78] [6]
Propofol DMB4OLE Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Propofol. Corneal disease [9A76-9A78] [6]
Sevoflurane DMC9O43 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Sevoflurane. Corneal disease [9A76-9A78] [6]
Methadone DMTW6IU Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Methadone. Cough [MD12] [6]
Clofazimine DMEBOFW Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Clofazimine. Crohn disease [DD70] [7]
Mifepristone DMGZQEF Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Mifepristone. Cushing syndrome [5A70] [6]
Pasireotide DMHM7JS Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Pasireotide. Cushing syndrome [5A70] [6]
Osilodrostat DMIJC9X Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Osilodrostat. Cushing syndrome [5A70] [7]
Sertraline DM0FB1J Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Sertraline. Depression [6A70-6A7Z] [6]
Fluoxetine DM3PD2C Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Fluoxetine. Depression [6A70-6A7Z] [6]
Selegiline DM6034S Moderate Additive hypertensive effects by the combination of Isoetharine and Selegiline. Depression [6A70-6A7Z] [5]
Duloxetine DM9BI7M Moderate Increased risk of rapid heart rate by the combination of Isoetharine and Duloxetine. Depression [6A70-6A7Z] [9]
Isocarboxazid DMAF1NB Moderate Additive hypertensive effects by the combination of Isoetharine and Isocarboxazid. Depression [6A70-6A7Z] [5]
Milnacipran DMBFE74 Moderate Increased risk of rapid heart rate by the combination of Isoetharine and Milnacipran. Depression [6A70-6A7Z] [9]
Escitalopram DMFK9HG Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Escitalopram. Depression [6A70-6A7Z] [6]
Tranylcypromine DMGB5RE Moderate Additive hypertensive effects by the combination of Isoetharine and Tranylcypromine. Depression [6A70-6A7Z] [10]
Desvenlafaxine DMHD4PE Moderate Additive hypertensive effects by the combination of Isoetharine and Desvenlafaxine. Depression [6A70-6A7Z] [9]
Phenelzine DMHIDUE Moderate Additive hypertensive effects by the combination of Isoetharine and Phenelzine. Depression [6A70-6A7Z] [5]
Trazodone DMK1GBJ Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Trazodone. Depression [6A70-6A7Z] [6]
Mirtazapine DML53ZJ Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Mirtazapine. Depression [6A70-6A7Z] [6]
Maprotiline DMPWB7T Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Maprotiline. Depression [6A70-6A7Z] [6]
Venlafaxine DMR6QH0 Moderate Increased risk of rapid heart rate by the combination of Isoetharine and Venlafaxine. Depression [6A70-6A7Z] [9]
Tetrabenazine DMYWQ0O Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Tetrabenazine. Dissociative neurological symptom disorder [6B60] [6]
Deutetrabenazine DMUPFLI Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Deutetrabenazine. Dystonic disorder [8A02] [6]
Ingrezza DMVPLNC Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Ingrezza. Dystonic disorder [8A02] [6]
Solifenacin DMG592Q Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Solifenacin. Functional bladder disorder [GC50] [6]
Pentamidine DMHZJCG Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Pentamidine. Fungal infection [1F29-1F2F] [6]
Ketoconazole DMPZI3Q Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Ketoconazole. Fungal infection [1F29-1F2F] [6]
Sunitinib DMCBJSR Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Sunitinib. Gastrointestinal stromal tumour [2B5B] [6]
Procarbazine DMIK367 Moderate Additive hypertensive effects by the combination of Isoetharine and Procarbazine. Hodgkin lymphoma [2B30] [5]
Fostemsavir DM50ILT Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Fostemsavir. Human immunodeficiency virus disease [1C60-1C62] [6]
Efavirenz DMC0GSJ Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Efavirenz. Human immunodeficiency virus disease [1C60-1C62] [6]
Saquinavir DMG814N Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Saquinavir. Human immunodeficiency virus disease [1C60-1C62] [6]
Lopinavir DMITQS0 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Lopinavir. Human immunodeficiency virus disease [1C60-1C62] [7]
Rilpivirine DMJ0QOW Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Rilpivirine. Human immunodeficiency virus disease [1C60-1C62] [6]
Fludrocortisone DMUDIR8 Minor Increased risk of hypokalemia by the combination of Isoetharine and Fludrocortisone. Hypo-osmolality/hyponatraemia [5C72] [4]
Crizotinib DM4F29C Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Crizotinib. Lung cancer [2C25] [6]
Ceritinib DMB920Z Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Ceritinib. Lung cancer [2C25] [6]
Osimertinib DMRJLAT Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Osimertinib. Lung cancer [2C25] [6]
Selpercatinib DMZR15V Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Selpercatinib. Lung cancer [2C25] [7]
Lumefantrine DM29GAD Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Lumefantrine. Malaria [1F40-1F45] [7]
Chloroquine DMSI5CB Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Chloroquine. Malaria [1F40-1F45] [6]
Hydroxychloroquine DMSIVND Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Hydroxychloroquine. Malaria [1F40-1F45] [6]
Quinine DMSWYF5 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Quinine. Malaria [1F40-1F45] [6]
Primaquine DMWQ16I Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Primaquine. Malaria [1F40-1F45] [6]
Mefloquine DMWT905 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Mefloquine. Malaria [1F40-1F45] [6]
Inotuzumab ozogamicin DMAC130 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Inotuzumab ozogamicin. Malignant haematopoietic neoplasm [2B33] [6]
Arsenic trioxide DM61TA4 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Arsenic trioxide. Mature B-cell lymphoma [2A85] [6]
Vemurafenib DM62UG5 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Vemurafenib. Melanoma [2C30] [6]
LGX818 DMNQXV8 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and LGX818. Melanoma [2C30] [6]
Panobinostat DM58WKG Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Panobinostat. Multiple myeloma [2A83] [6]
Siponimod DM2R86O Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Siponimod. Multiple sclerosis [8A40] [6]
Fingolimod DM5JVAN Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Fingolimod. Multiple sclerosis [8A40] [6]
Ozanimod DMT6AM2 Major Increased risk of ventricular arrhythmias by the combination of Isoetharine and Ozanimod. Multiple sclerosis [8A40] [11]
Romidepsin DMT5GNL Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Romidepsin. Mycosis fungoides [2B01] [7]
Nilotinib DM7HXWT Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Nilotinib. Myeloproliferative neoplasm [2A20] [6]
Dasatinib DMJV2EK Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Dasatinib. Myeloproliferative neoplasm [2A20] [6]
Droperidol DM0DXA8 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Droperidol. Nausea/vomiting [MD90] [6]
Prochlorperazine DM53SRA Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Prochlorperazine. Nausea/vomiting [MD90] [6]
Promethazine DM6I5GR Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Promethazine. Nausea/vomiting [MD90] [6]
Palonosetron DMBHMOX Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Palonosetron. Nausea/vomiting [MD90] [6]
Granisetron DMIUW25 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Granisetron. Nausea/vomiting [MD90] [6]
Dolasetron DMMG26Z Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Dolasetron. Nausea/vomiting [MD90] [6]
Ondansetron DMOTQ1I Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Ondansetron. Nausea/vomiting [MD90] [6]
Entrectinib DMMPTLH Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Entrectinib. Non-small cell lung cancer [2C25] [7]
Sibutramine DMFJTDI Moderate Increased risk of rapid heart rate by the combination of Isoetharine and Sibutramine. Obesity [5B80-5B81] [12]
Lofexidine DM1WXA6 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Lofexidine. Opioid use disorder [6C43] [6]
Rucaparib DM9PVX8 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Rucaparib. Ovarian cancer [2C73] [6]
Dextropropoxyphene DM23HCX Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Dextropropoxyphene. Pain [MG30-MG3Z] [7]
Buprenorphine DMPRI8G Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Buprenorphine. Pain [MG30-MG3Z] [6]
Triclabendazole DMPWGBR Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Triclabendazole. Parasitic worm infestation [1F90] [7]
Safinamide DM0YWJC Moderate Additive hypertensive effects by the combination of Isoetharine and Safinamide. Parkinsonism [8A00] [5]
Opicapone DM1BKA6 Moderate Decreased metabolism of Isoetharine caused by Opicapone mediated inhibition of non-CYP450 enzyme. Parkinsonism [8A00] [13]
Rasagiline DM3WKQ4 Moderate Additive hypertensive effects by the combination of Isoetharine and Rasagiline. Parkinsonism [8A00] [5]
Tolcapone DM8MNVO Moderate Decreased metabolism of Isoetharine caused by Tolcapone mediated inhibition of non-CYP450 enzyme. Parkinsonism [8A00] [13]
Entacapone DMLBVKQ Moderate Decreased metabolism of Isoetharine caused by Entacapone mediated inhibition of non-CYP450 enzyme. Parkinsonism [8A00] [13]
Pimavanserin DMR7IVC Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Pimavanserin. Parkinsonism [8A00] [6]
Apomorphine DMX38HQ Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Apomorphine. Parkinsonism [8A00] [6]
Famotidine DMRL3AB Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Famotidine. Peptic ulcer [DA61] [14]
Macimorelin DMQYJIR Major Increased risk of prolong QT interval by the combination of Isoetharine and Macimorelin. Pituitary gland disorder [5A60-5A61] [15]
Lefamulin DME6G97 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Lefamulin. Pneumonia [CA40] [6]
Prednisone DM2HG4X Minor Increased risk of hypokalemia by the combination of Isoetharine and Prednisone. Postoperative inflammation [1A00-CA43] [4]
Betamethasone DMAHJEF Minor Increased risk of hypokalemia by the combination of Isoetharine and Betamethasone. Postoperative inflammation [1A00-CA43] [4]
Hydrocortisone DMGEMB7 Minor Increased risk of hypokalemia by the combination of Isoetharine and Hydrocortisone. Postoperative inflammation [1A00-CA43] [4]
Degarelix DM3O8QY Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Degarelix. Prostate cancer [2C82] [6]
ABIRATERONE DM8V75C Moderate Increased risk of prolong QT interval by the combination of Isoetharine and ABIRATERONE. Prostate cancer [2C82] [6]
Nilutamide DMFN07X Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Nilutamide. Prostate cancer [2C82] [6]
Enzalutamide DMGL19D Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Enzalutamide. Prostate cancer [2C82] [6]
Flutamide DMK0O7U Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Flutamide. Prostate cancer [2C82] [6]
Bicalutamide DMZMSPF Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Bicalutamide. Prostate cancer [2C82] [6]
Alfuzosin DMZVMKF Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Alfuzosin. Prostate hyperplasia [GA90] [6]
Fluphenazine DMIT8LX Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Fluphenazine. Psychotic disorder [6A20-6A25] [6]
Sorafenib DMS8IFC Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Sorafenib. Renal cell carcinoma [2C90] [6]
Gatifloxacin DMSL679 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Gatifloxacin. Respiratory infection [CA07-CA4Z] [7]
Ciclesonide DM2NA4K Minor Increased risk of hypokalemia by the combination of Isoetharine and Ciclesonide. Respiratory system disease [CB40-CB7Z] [4]
Dexamethasone DMMWZET Minor Increased risk of hypokalemia by the combination of Isoetharine and Dexamethasone. Rheumatoid arthritis [FA20] [4]
Quetiapine DM1N62C Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Quetiapine. Schizophrenia [6A20] [6]
Mesoridazine DM2ZGAN Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Mesoridazine. Schizophrenia [6A20] [7]
Thioridazine DM35M8J Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Thioridazine. Schizophrenia [6A20] [7]
Aripiprazole DM3NUMH Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Aripiprazole. Schizophrenia [6A20] [14]
Iloperidone DM6AUFY Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Iloperidone. Schizophrenia [6A20] [6]
Paliperidone DM7NPJS Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Paliperidone. Schizophrenia [6A20] [6]
Haloperidol DM96SE0 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Haloperidol. Schizophrenia [6A20] [6]
Perphenazine DMA4MRX Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Perphenazine. Schizophrenia [6A20] [6]
Chlorpromazine DMBGZI3 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Chlorpromazine. Schizophrenia [6A20] [6]
Clozapine DMFC71L Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Clozapine. Schizophrenia [6A20] [6]
Trifluoperazine DMKBYWI Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Trifluoperazine. Schizophrenia [6A20] [6]
Ziprasidone DMM58JY Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Ziprasidone. Schizophrenia [6A20] [6]
Risperidone DMN6DXL Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Risperidone. Schizophrenia [6A20] [6]
Olanzapine DMPFN6Y Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Olanzapine. Schizophrenia [6A20] [14]
Amisulpride DMSJVAM Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Amisulpride. Schizophrenia [6A20] [6]
Asenapine DMSQZE2 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Asenapine. Schizophrenia [6A20] [6]
Pimozide DMW83TP Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Pimozide. Schizophrenia [6A20] [6]
Vardenafil DMTBGW8 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Vardenafil. Sexual dysfunction [HA00-HA01] [6]
Methylprednisolone DM4BDON Minor Increased risk of hypokalemia by the combination of Isoetharine and Methylprednisolone. Solid tumour/cancer [2A00-2F9Z] [4]
LEE011 DMMX75K Major Increased risk of prolong QT interval by the combination of Isoetharine and LEE011. Solid tumour/cancer [2A00-2F9Z] [16]
Epirubicin DMPDW6T Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Epirubicin. Solid tumour/cancer [2A00-2F9Z] [6]
Prednisolone DMQ8FR2 Minor Increased risk of hypokalemia by the combination of Isoetharine and Prednisolone. Solid tumour/cancer [2A00-2F9Z] [4]
Vandetanib DMRICNP Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Vandetanib. Solid tumour/cancer [2A00-2F9Z] [6]
Triptorelin DMTK4LS Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Triptorelin. Solid tumour/cancer [2A00-2F9Z] [6]
Doxorubicin DMVP5YE Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Doxorubicin. Solid tumour/cancer [2A00-2F9Z] [6]
Telavancin DM58VQX Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Telavancin. Staphylococcal/streptococcal disease [1B5Y] [6]
Ibutilide DMKXY2R Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Ibutilide. Supraventricular tachyarrhythmia [BC81] [6]
Anagrelide DMSQ8MD Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Anagrelide. Thrombocytosis [3B63] [6]
Lenvatinib DMB1IU4 Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Lenvatinib. Thyroid cancer [2D10] [6]
Tacrolimus DMZ7XNQ Moderate Increased risk of ventricular arrhythmias by the combination of Isoetharine and Tacrolimus. Transplant rejection [NE84] [6]
Triamcinolone DM98IXF Minor Increased risk of hypokalemia by the combination of Isoetharine and Triamcinolone. Vasomotor/allergic rhinitis [CA08] [4]
Fluticasone DMGCSVF Minor Increased risk of hypokalemia by the combination of Isoetharine and Fluticasone. Vasomotor/allergic rhinitis [CA08] [4]
Disopyramide DM5SYZP Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Disopyramide. Ventricular tachyarrhythmia [BC71] [6]
Procainamide DMNMXR8 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Procainamide. Ventricular tachyarrhythmia [BC71] [6]
Propafenone DMPIBJK Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Propafenone. Ventricular tachyarrhythmia [BC71] [6]
Flecainide DMSQDLE Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Flecainide. Ventricular tachyarrhythmia [BC71] [6]
Amiodarone DMUTEX3 Moderate Increased risk of prolong QT interval by the combination of Isoetharine and Amiodarone. Ventricular tachyarrhythmia [BC71] [6]
⏷ Show the Full List of 168 DDI Information of This Drug

References

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