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Core 1-derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer.J Exp Med. 2020 Jan 6;217(1):e20182325. doi: 10.1084/jem.20182325.
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Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathway.Oncotarget. 2015 Mar 20;6(8):6123-35. doi: 10.18632/oncotarget.3045.
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Relevance of Gal-GalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients.Breast Cancer Res Treat. 2015 Jun;151(3):515-28. doi: 10.1007/s10549-015-3425-0. Epub 2015 May 15.
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Knockdown of C1GalT1 inhibits radioresistance of human esophageal cancer cells through modifying 1-integrin glycosylation.J Cancer. 2018 Jun 23;9(15):2666-2677. doi: 10.7150/jca.25252. eCollection 2018.
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Leveraging Polygenic Functional Enrichment to Improve GWAS Power.Am J Hum Genet. 2019 Jan 3;104(1):65-75. doi: 10.1016/j.ajhg.2018.11.008. Epub 2018 Dec 27.
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O-Glycosylation-mediated signaling circuit drives metastatic castration-resistant prostate cancer.FASEB J. 2018 Jun 15:fj201800687. doi: 10.1096/fj.201800687. Online ahead of print.
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Suppression of core 1 Gal-transferase is associated with reduction of TF and reciprocal increase of Tn, sialyl-Tn and Core 3 glycans in human colon cancer cells.PLoS One. 2013;8(3):e59792. doi: 10.1371/journal.pone.0059792. Epub 2013 Mar 25.
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T-Synthase Deficiency Enhances Oncogenic Features in Human Colorectal Cancer Cells via Activation of Epithelial-Mesenchymal Transition.Biomed Res Int. 2018 Jun 21;2018:9532389. doi: 10.1155/2018/9532389. eCollection 2018.
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C1GALT1 Seems to Promote In Vitro Disease Progression in Ovarian Cancer.Int J Gynecol Cancer. 2017 Jun;27(5):863-871. doi: 10.1097/IGC.0000000000000965.
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Clinic implication of MUC1 O-glycosylation and C1GALT1 in esophagus squamous cell carcinoma.Sci China Life Sci. 2018 Nov;61(11):1389-1395. doi: 10.1007/s11427-017-9345-7. Epub 2018 Aug 1.
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C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer.Oncogene. 2018 Oct;37(43):5780-5793. doi: 10.1038/s41388-018-0375-0. Epub 2018 Jun 21.
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C1GALT1 promotes invasive phenotypes of hepatocellular carcinoma cells by modulating integrin 1 glycosylation and activity.PLoS One. 2014 Aug 4;9(8):e94995. doi: 10.1371/journal.pone.0094995. eCollection 2014.
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A Polymeric Nanogel-Based Treatment Regimen for Enhanced Efficacy and Sequential Administration of Synergistic Drug Combination in Pancreatic Cancer.J Pharmacol Exp Ther. 2019 Sep;370(3):894-901. doi: 10.1124/jpet.118.255372. Epub 2019 Jan 25.
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Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers.BMC Cancer. 2018 Aug 16;18(1):827. doi: 10.1186/s12885-018-4708-8.
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Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene.Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16442-7. doi: 10.1073/pnas.0607872103. Epub 2006 Oct 24.
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A study on the association between C1GALT1 polymorphisms and the risk of Henoch-Schnlein purpura in a Chinese population.Rheumatol Int. 2013 Oct;33(10):2539-42. doi: 10.1007/s00296-013-2761-9. Epub 2013 Apr 27.
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Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.Respir Res. 2019 Apr 2;20(1):64. doi: 10.1186/s12931-019-1036-8.
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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Arch Toxicol. 2013 Jan;87(1):123-43.
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Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.
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Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophen. Clin Pharmacol Ther. 2016 Apr;99(4):432-41.
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Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. J Cell Physiol. 2021 Apr;236(4):2959-2975. doi: 10.1002/jcp.30055. Epub 2020 Sep 22.
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Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells. Mutagenesis. 2011 Sep;26(5):593-604.
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Temozolomide induces activation of Wnt/-catenin signaling in glioma cells via PI3K/Akt pathway: implications in glioma therapy. Cell Biol Toxicol. 2020 Jun;36(3):273-278. doi: 10.1007/s10565-019-09502-7. Epub 2019 Nov 22.
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The exosome-like vesicles derived from androgen exposed-prostate stromal cells promote epithelial cells proliferation and epithelial-mesenchymal transition. Toxicol Appl Pharmacol. 2021 Jan 15;411:115384. doi: 10.1016/j.taap.2020.115384. Epub 2020 Dec 25.
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A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
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Characterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells. Arch Toxicol. 2013 Nov;87(11):1999-2012.
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Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study. Oncotarget. 2017 Jan 3;8(1):1369-1391. doi: 10.18632/oncotarget.13622.
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Cell-based two-dimensional morphological assessment system to predict cancer drug-induced cardiotoxicity using human induced pluripotent stem cell-derived cardiomyocytes. Toxicol Appl Pharmacol. 2019 Nov 15;383:114761. doi: 10.1016/j.taap.2019.114761. Epub 2019 Sep 15.
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From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch Toxicol. 2014 Jul;88(7):1451-68.
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Transcriptional profiling of lactic acid treated reconstructed human epidermis reveals pathways underlying stinging and itch. Toxicol In Vitro. 2019 Jun;57:164-173.
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