Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYHDCA)

Drug Name
Pranlukast Drug Info
Synonyms Azlaire; Azlaire (TN); Pranlukast (INN); N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide
Indication
Disease Entry ICD 11 Status REF
Allergic rhinitis CA08.0 Approved [1]
Asthma CA23 Approved [2]
Therapeutic Class
Antiasthmatic Agents
Cross-matching ID
PubChem CID
4887
ChEBI ID
CHEBI:94810
CAS Number
CAS 103177-37-3
TTD Drug ID
DMYHDCA
VARIDT Drug ID
DR01179
INTEDE Drug ID
DR1321

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Leukotriene CysLT1 receptor (CYSLTR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Montelukast DMD157S Allergic asthma CA23.0 Approved [10]
Zafirlukast DMHNQOG Asthma CA23 Approved [11]
Cinalukast DMFIC0M Asthma CA23 Approved [12]
KP-496 DMCO8UZ Asthma CA23 Phase 2 [13]
BAY-X-7195 DM2XE80 Asthma CA23 Phase 2 [14]
Masilukast DMDTI0L Asthma CA23 Phase 2 [15]
LM-1507.NA DMW6VA0 Asthma CA23 Phase 2 [16]
Iralukast DMQ3RWN Asthma CA23 Phase 2 [17]
YM-57158 DMS31YW Allergic rhinitis CA08.0 Phase 1 [18]
CR-3465 DMT7L30 Allergy 4A80-4A85 Phase 1 [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [20]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [21]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [22]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [24]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [25]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [26]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [20]
Verapamil DMA7PEW Angina pectoris BA40 Approved [27]
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Drug(s) Affected By Cysteinyl leukotriene receptor 1 (CYSLTR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zafirlukast DMHNQOG Asthma CA23 Approved [6]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [30]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [31]
PMID28870136-Compound-48 DMPIM9L N. A. N. A. Patented [28]
LTC4 DM702WR Discovery agent N.A. Investigative [6]
LTE4 DMCPB0Q Discovery agent N.A. Investigative [32]
BAYu9773 DMXQ14V Discovery agent N.A. Investigative [6]
CGP-57698 DMYZ72J Discovery agent N.A. Investigative [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [33]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [34]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [35]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [36]
Capsaicin DMGMF6V Back pain ME84.Z Approved [37]
Zafirlukast DMHNQOG Asthma CA23 Approved [7]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [35]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [38]
Fluconazole DMOWZ6B Cryptococcal meningitis Approved [36]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [35]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [39]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [40]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [40]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [41]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [39]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [40]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [42]
Gefitinib DM15F0X Colon adenocarcinoma Approved [39]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [5]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [39]
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Drug(s) Affected By Interleukin-5 (IL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [43]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [44]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [45]
Prednisone DM2HG4X Acute asthma CA23 Approved [46]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [47]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [48]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [49]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [50]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [51]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [52]
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Drug(s) Affected By Leukotriene C4 synthase (LTC4S)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [56]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [57]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [58]
Etazolate DMOCID7 Neurodegenerative disorder 8A20-8A23 Phase 2 [59]
PMID28870136-Compound-48 DMPIM9L N. A. N. A. Patented [59]
Forskolin DM6ITNG Solid tumour/cancer 2A00-2F9Z Investigative [59]
ROLIPRAM DMJ03UM Discovery agent N.A. Investigative [59]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leukotriene CysLT1 receptor (CYSLTR1) TTGKOY9 CLTR1_HUMAN Antagonist [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [5]
Cysteinyl leukotriene receptor 1 (CYSLTR1) OT904HBN CLTR1_HUMAN Protein Interaction/Cellular Processes [6]
Cytochrome P450 2C9 (CYP2C9) OTGLBN29 CP2C9_HUMAN Gene/Protein Processing [7]
Interleukin-5 (IL5) OTAFPSCO IL5_HUMAN Gene/Protein Processing [8]
Leukotriene C4 synthase (LTC4S) OT3XNFJZ LTC4S_HUMAN Drug Response [9]

References

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