General Information of Drug (ID: DM8SXYG)

Drug Name
Lamotrigine Drug Info
Synonyms
Crisomet; Labileno; Lamictal; Lamictin; Lamiktal; Lamitor; Lamotrigina; Lamotriginum; Desitin Brand of Lamotrigine; Faes Brand of Lamotrigine; Glaxo Wellcome Brand of Lamotrigine; GlaxoSmithKline Brand of Lamotrigine; Juste Brand of Lamotrigine; Lamictal Cd; Lamictal ODT; Lamictal XR; Lamotrigina [Spanish]; Lamotriginum [Latin]; BW 430C; GI 267119X; GW 273293; L 3791; BW-430C; EUR-1048; Lamictal (TN); Lamictin (TN); Lamotrigine [USAN:INN:BAN]; Lamotrigine (JAN/USAN/INN); 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine; 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine; 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diyldiamine; 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
Indication
Disease Entry ICD 11 Status REF
Bipolar disorder 6A60 Approved [1]
Epilepsy 8A60-8A68 Approved [1]
Therapeutic Class
Anticonvulsants
Cross-matching ID
PubChem CID
3878
ChEBI ID
CHEBI:6367
CAS Number
CAS 84057-84-1
TTD Drug ID
DM8SXYG
VARIDT Drug ID
DR00056
INTEDE Drug ID
DR0913
ACDINA Drug ID
D00348

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [13]
Lacosamide DMVM6QR Convulsion 8A68.Z Approved [14]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [15]
Tolperisone DMA2GHJ Muscle spasm MB47.3 Approved [16]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [17]
Eslicarbazepine DMZREFQ Seizure disorder 8A6Z Approved [14]
Oxcarbazepine DM5PU6O Epilepsy 8A60-8A68 Approved [18]
HP-184 DMNOMV2 Multiple sclerosis 8A40 Phase 2 [19]
QX-314 DMAV2FM Pain MG30-MG3Z Terminated [20]
PD-32577 DMBA15J Discovery agent N.A. Investigative [21]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [22]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [23]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Folic Acid DMEMBJC Colorectal carcinoma Approved [25]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [24]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [24]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [26]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [24]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [27]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [28]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [29]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [30]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [31]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [32]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [22]
Verapamil DMA7PEW Angina pectoris BA40 Approved [33]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [34]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [35]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [36]
Propranolol DM79NTF Angina pectoris BA40 Approved [37]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [38]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [40]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [41]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [42]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [43]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [44]
Metronidazole DMTIVEN Abscess Approved [5]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [45]
Ethanol DMDRQZU Chronic pain MG30 Approved [46]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [43]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [48]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [49]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [50]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [52]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [53]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [54]
Losartan DM72JXH Diabetic kidney disease GB61.Z Approved [48]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Lorlatinib DMICDLV Non-small-cell lung cancer 2C25.Y Approved [55]
Rilpivirine DMJ0QOW Human immunodeficiency virus infection 1C62 Approved [56]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [57]
Bevirimat DML2D8Q Human immunodeficiency virus infection 1C62 Phase 2 [58]
LM-94 DMW3QGJ N. A. N. A. Phase 1/2 [59]
UDP-glucuronic acid DMW16X2 Discovery agent N.A. Investigative [59]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [60]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [61]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [62]
Cepharanthine DM9Y5JB N. A. N. A. Approved [63]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [64]
Clozapine DMFC71L Schizophrenia 6A20 Approved [65]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [66]
Trifluoperazine DMKBYWI Anxiety Approved [67]
Olanzapine DMPFN6Y Bipolar depression Approved [65]
Levetiracetam DMTGDN8 Epilepsy 8A60-8A68 Approved [11]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [68]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [69]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [72]
Testosterone DM7HUNW Hot flushes GA30 Approved [72]
Pyruvic acid DM7Q41G Malnutrition 5B50-5B71 Approved [73]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [8]
ABIRATERONE DM8V75C Prostate cancer 2C82.0 Approved [74]
Duloxetine DM9BI7M Depression 6A70-6A7Z Approved [75]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [8]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Metyrapone DMI7FVQ Cushing disease 5A70 Approved [78]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [70]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [79]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [80]
Levetiracetam DMTGDN8 Epilepsy 8A60-8A68 Approved [77]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [81]
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Drug(s) Affected By Aromatase (CYP19A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [82]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [83]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [84]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [85]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [84]
Methotrexate DM2TEOL Anterior urethra cancer Approved [86]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [69]
Bifonazole DM3KN7V Fungal infection 1F29-1F2F Approved [87]
Quercetin DM3NC4M Obesity 5B81 Approved [88]
Fluoxetine DM3PD2C Bipolar depression Approved [84]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [89]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [90]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [91]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Ethanol DMDRQZU Chronic pain MG30 Approved [92]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [93]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [94]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [95]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [97]
Quercetin DM3NC4M Obesity 5B81 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Panobinostat DM58WKG Chronic graft versus host disease Approved [100]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [101]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [102]
Testosterone DM7HUNW Hot flushes GA30 Approved [103]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [104]
Leflunomide DMR8ONJ Arthritis FA20 Approved [105]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [106]
Quinidine DMLPICK N. A. N. A. Approved [107]
Verapamil DMA7PEW Angina pectoris BA40 Approved [108]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [109]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [109]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [110]
Propranolol DM79NTF Angina pectoris BA40 Approved [111]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [112]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [113]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [109]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [114]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [115]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [114]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [117]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [118]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [119]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [120]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [122]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [125]
Arsenic DMTL2Y1 N. A. N. A. Approved [126]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [127]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Napabucasin DMDZ6Q3 Colorectal cancer 2B91.Z Phase 3 [129]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [122]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [130]
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Drug(s) Affected By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tegafur DM31ZQM Solid tumour/cancer 2A00-2F9Z Approved [131]
Methoxsalen DME8FZ9 Cutaneous T-cell lymphoma 2B01 Approved [132]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [136]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [139]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [140]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [122]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [130]
Forskolin DM6ITNG Solid tumour/cancer 2A00-2F9Z Investigative [141]
Drug(s) Affected By Histamine H1 receptor (HRH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Desloratadine DM56YN7 Allergic rhinitis CA08.0 Approved [142]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [142]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [143]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [144]
Methotrexate DM2TEOL Anterior urethra cancer Approved [86]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [146]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [147]
Clozapine DMFC71L Schizophrenia 6A20 Approved [148]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [79]
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Drug(s) Affected By D(2) dopamine receptor (DRD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Droperidol DM0DXA8 Nausea MD90 Approved [143]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [143]
Zuclopenthixol DMKYD5N Schizophrenia 6A20 Approved [143]
Meglitinides DM1OFHN Type-2 diabetes 5A11 Approved [149]
Sulpiride DMF54ZG Schizophrenia 6A20 Approved [150]
Risperidone DMN6DXL Bipolar I disorder Approved [151]
Olanzapine DMPFN6Y Bipolar depression Approved [152]
Methamphetamine DMPM4SK Anxiety Approved [153]
Bromocriptine DMVE3TK Acromegaly 5A60.0 Approved [154]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [155]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [147]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [158]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Bromocriptine DMVE3TK Acromegaly 5A60.0 Approved [158]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [159]
Artesunate DMR27C8 Infection of P. falciparum 1F40 Approved [160]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [161]
Urethane DM7NSI0 N. A. N. A. Phase 4 [162]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [163]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [85]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Selenium DM25CGV N. A. N. A. Approved [164]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [165]
Methotrexate DM2TEOL Anterior urethra cancer Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [166]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [167]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [168]
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Drug(s) Affected By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fomepizole DM6VOWQ Athylene glycol or methanol poisoning NE61 Approved [169]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [170]
Theophylline DMRJFN9 Bronchitis CA20 Approved [143]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [171]
Ethanol DMDRQZU Chronic pain MG30 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [173]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [147]
Didanosine DMI2QPE Human immunodeficiency virus infection 1C62 Approved [143]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [174]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [175]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [176]
Allopurinol DMLPAOB Gout FA25 Approved [177]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [147]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [179]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [180]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [181]
Flucloxacillin DMNUWST Bacterial infection 1A00-1C4Z Approved [182]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [183]
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Drug(s) Affected By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [184]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [185]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [186]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [187]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [188]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [189]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [190]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [191]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [192]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [193]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [194]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [195]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [196]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [197]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [198]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [198]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [142]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [199]
Capsaicin DMGMF6V Back pain ME84.Z Approved [200]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [201]
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Drug(s) Affected By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [202]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [203]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [204]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [206]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [207]
Capsaicin DMGMF6V Back pain ME84.Z Approved [208]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [198]
Quinidine DMLPICK N. A. N. A. Approved [209]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [210]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Voltage-gated sodium channel alpha Nav1.9 (SCN11A) TTN9VTF SCNBA_HUMAN Blocker [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [3]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [5]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DEF2WXN UD13_HUMAN Substrate [6]
UDP-glucuronosyltransferase 1A4 (UGT1A4) DELOY3P UD14_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2) OT02MSKN 3BHS2_HUMAN Gene/Protein Processing [8]
Adrenocorticotropic hormone receptor (MC2R) OT6V19Y9 ACTHR_HUMAN Drug Response [9]
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Gene/Protein Processing [10]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [11]
Cytochrome P450 2A6 (CYP2A6) OT52TWG3 CP2A6_HUMAN Drug Response [12]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Biotransformations [12]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Biotransformations [12]
Cytochrome P450 2E1 (CYP2E1) OTHQ17JG CP2E1_HUMAN Biotransformations [12]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Biotransformations [12]
D(2) dopamine receptor (DRD2) OTBLXKEG DRD2_HUMAN Drug Response [9]

References

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