General Information of Drug (ID: DMH61ZB)

Drug Name
Cimetidine Drug Info
Synonyms
Acibilin; Acinil; Altramet; Brumetidina; Cimal; Cimetadine; Cimetag; Cimetidina; Cimetidinum; Cimetum; Dyspamet; Edalene; Eureceptor; Evicer; Gastrobitan; Gastromet; Histodil; Magicul; Metracin; Peptol; Sigmetadine; Tagamet; Tametin; Tratul; Ulcedin; Ulcedine; Ulcestop; Ulcimet; Ulcofalk; Ulcomedina; Ulcomet; Ulhys; Valmagen; Venopex; Ci metum; Cimetidine Hcl; Tagamet Hb; Biomet400; C 4522; FPF 1002; SKF 92334; Tagamet Hb 200; CIMETIDINE A/AB; Cimetidina [INN-Spanish]; Cimetidinum [INN-Latin]; DRG-0150; SKF-92334; Tagamet (TN); Tagamet HB (TN); Tagamet HB200 (TN); SK&F-92334; Cimetidine (JP15/USP/INN); Cimetidine [USAN:INN:BAN:JAN]; Tagamet, SKF-92334, Tratul, Tametin, Dyspamet, Acinil, Cimetidine; N-Cyano-N'-methyl-[2-[[[5-methyl-1H-imidazol-4-yl]methyl]thio]ethyl]guanidine; N''-Cyano-N-methyl-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine; N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine; N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidine; N-cyano-N'-methyl-N''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine; N-Cyano-N'-Methyl-N''-(2-(((5-Methyl-1H-Imidazol-4-YL)Methyl)Thio)Ethyl) Guanidine; N-Cyano-N'-methyl-N''-(2-(((5-methyl-1 H-imidazol-4-yl) methyl)thio)ethyl)guanidine; N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine; N''-cyano-N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)-ethyl)guanidine; 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine; 1-Cyano-2-methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]guanidine; 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine; 2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine; 2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine; 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine; 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
Indication
Disease Entry ICD 11 Status REF
Acid-reflux disorder DA22 Approved [1]
Gastric ulcer DA60 Approved [2]
Gastrinoma 2C10.1 Approved [2]
Therapeutic Class
Antiulcer Agents
Cross-matching ID
PubChem CID
2756
ChEBI ID
CHEMBL30
CAS Number
CAS 51481-61-9
TTD Drug ID
DMH61ZB
VARIDT Drug ID
DR00037
INTEDE Drug ID
DR2272
ACDINA Drug ID
D00130

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Discontinued Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Histamine H2 receptor (H2R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [17]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [3]
Nizatidine DMGFV3Z Acid-reflux disorder DA22 Approved [18]
Betazole DMUFGAY Gastric secretory disorder DD90 Approved [19]
Ebrotidine DMV5KR3 Duodenal ulcer DA63 Withdrawn from market [20]
Pibutidine DMXSTRM Ulcerative colitis DD71 Discontinued in Phase 3 [21]
Osutidine DMN7TL8 Duodenal ulcer DA63 Discontinued in Phase 3 [22]
KU-1257 DMZMFX6 Duodenal ulcer DA63 Discontinued in Phase 3 [23]
Lavoltidine DMTY5VE Gastroesophageal reflux disease DA22.Z Discontinued in Phase 2 [24]
IGN-2098 DMU4N1O Duodenal ulcer DA63 Discontinued in Phase 2 [25]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [26]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [9]
Folic Acid DMEMBJC Colorectal carcinoma Approved [28]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [9]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [9]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [29]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [9]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [30]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [31]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
Folic Acid DMEMBJC Colorectal carcinoma Approved [34]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [35]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [36]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [37]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [38]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [37]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [39]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [40]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [42]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [43]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [44]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [45]
Propranolol DM79NTF Angina pectoris BA40 Approved [46]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [47]
Metformin DM89QE1 Colorectal carcinoma Approved [48]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [46]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [49]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Aciclovir DMYLOVR Genital herpes 1A94 Approved [5]
Metformin DM89QE1 Colorectal carcinoma Approved [50]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [5]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [51]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [5]
Topotecan DMP6G8T Central nervous system neoplasm Approved [5]
Cephalexin DMD5JU8 Acute otitis media AB00 Approved [52]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [53]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [54]
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [55]
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [73]
Verapamil DMA7PEW Angina pectoris BA40 Approved [74]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [15]
Methotrexate DM2TEOL Anterior urethra cancer Approved [75]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [79]
Quinidine DMLPICK N. A. N. A. Approved [15]
Mebendazole DMO14SG Ascariasis 1F62 Approved [80]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [56]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [57]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [58]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [59]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [60]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [61]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [62]
Propranolol DM79NTF Angina pectoris BA40 Approved [46]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [64]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [65]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [66]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [67]
L-Tryptophan DMIBH7M Depression 6A70-6A7Z Approved [68]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [69]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [70]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [71]
Cilostazol DMZMSCT Intermittent claudication BD40.00 Approved [72]
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [96]
Methotrexate DM2TEOL Anterior urethra cancer Approved [97]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [98]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [66]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [49]
Cefdinir DMJ7A0H Bacterial infection 1A00-1C4Z Approved [99]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [99]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [100]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [101]
Quercetin DM3NC4M Obesity 5B81 Approved [102]
⏷ Show the Full List of 20 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aciclovir DMYLOVR Genital herpes 1A94 Approved [5]
Metformin DM89QE1 Colorectal carcinoma Approved [5]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [5]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [5]
Topotecan DMP6G8T Central nervous system neoplasm Approved [5]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [53]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [54]
Estrone sulfate DMVBIZL Atrophic vaginitis GA30.2 Approved [5]
N-methylpyridinium DMVUKEW N. A. N. A. Preclinical [5]
[14C]TEA DM6SFYH Discovery agent N.A. Investigative [5]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [82]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [49]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [83]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [84]
Trospium chloride DM32XZT Discovery agent N.A. Approved [85]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [86]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [87]
Indomethacin DMSC4A7 Bursitis Approved [84]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [88]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [88]
Gefitinib DM15F0X Colon adenocarcinoma Approved [89]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [12]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [90]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [91]
Methotrexate DM2TEOL Anterior urethra cancer Approved [92]
Quercetin DM3NC4M Obesity 5B81 Approved [93]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [94]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [95]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [103]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [103]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [104]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [105]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [106]
Etidronic acid DM1XHYJ Bone Paget disease Approved [103]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [103]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [103]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [107]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [108]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [107]
Quercetin DM3NC4M Obesity 5B81 Approved [109]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [110]
Artemether DM48QOT Malaria 1F40-1F45 Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [113]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [16]
Estrone DM5T6US Acne vulgaris ED80 Approved [114]
Leflunomide DMR8ONJ Arthritis FA20 Approved [115]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [116]
Methotrexate DM2TEOL Anterior urethra cancer Approved [117]
Quercetin DM3NC4M Obesity 5B81 Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [122]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [124]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [126]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [127]
Goserelin DMAT8CG Breast cancer 2C60-2C65 Approved [128]
Folic Acid DMEMBJC Colorectal carcinoma Approved [129]
Cetrorelix DMFD9Q6 Ovarian stimulation LB45.1 Approved [130]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [131]
Risperidone DMN6DXL Bipolar I disorder Approved [132]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [133]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [134]
Naltrexone DMUL45H Alcohol dependence 6C40.2 Approved [135]
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Drug(s) Affected By Integrin alpha-X (ITGAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [137]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [138]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [139]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [140]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [141]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [142]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [142]
Ardeparin DMYRX8B Deep vein thrombosis BD71 Approved [143]
Bryostatin-1 DM1JOXY Alzheimer disease 8A20 Phase 2 [144]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [145]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [146]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [147]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [148]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [149]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [150]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [151]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [152]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [145]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [154]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [156]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [147]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [153]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [158]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [159]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [160]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [161]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [147]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [125]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [162]
Bortezomib DMNO38U Leukemia Approved [163]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [134]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [165]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [12]
Sirolimus DMGW1ID Advanced cancer 2A00-2F9Z Approved [12]
Tacrolimus DMZ7XNQ Graft-versus-host disease 4B24 Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [97]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [84]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [84]
Quercetin DM3NC4M Obesity 5B81 Approved [102]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [84]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [84]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [166]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [84]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [167]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [84]
Methotrexate DM2TEOL Anterior urethra cancer Approved [168]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [94]
Paclitaxel DMLB81S Breast carcinoma Approved [169]
Allopurinol DMLPAOB Gout FA25 Approved [169]
Bumetanide DMRV7H0 Congestive heart failure BD10 Approved [169]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [169]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [169]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [169]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Epinephrine DM3KJBC Acute asthma CA23 Approved [170]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [170]
Norepinephrine DMOUC09 Alopecia ED70 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [171]
Quercetin DM3NC4M Obesity 5B81 Approved [172]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [87]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [173]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [174]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histamine H2 receptor (H2R) TTQHJ1K HRH2_HUMAN Antagonist [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [4]
Multidrug and toxin extrusion protein 2 (SLC47A2) DT3TX4H S47A2_HUMAN Substrate [5]
Multidrug and toxin extrusion protein 1 (SLC47A1) DTZGT0P S47A1_HUMAN Substrate [5]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [6]
Organic cation transporter 2 (SLC22A2) DT9IDPW S22A2_HUMAN Substrate [7]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [8]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [9]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Gene/Protein Processing [10]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Regulation of Drug Effects [11]
Calcineurin subunit B type 1 (PPP3R1) OTGQNFJQ CANB1_HUMAN Drug Response [12]
Follitropin subunit beta (FSHB) OTGLS283 FSHB_HUMAN Gene/Protein Processing [13]
Integrin alpha-X (ITGAX) OTOGIMHE ITAX_HUMAN Gene/Protein Processing [14]
L-lactate dehydrogenase B chain (LDHB) OT9B1CT3 LDHB_HUMAN Drug Response [12]
L-lactate dehydrogenase C chain (LDHC) OTBX9DI5 LDHC_HUMAN Drug Response [12]
Multidrug and toxin extrusion protein 1 (SLC47A1) OTZX0U5Q S47A1_HUMAN Gene/Protein Processing [15]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Gene/Protein Processing [16]
Nuclear receptor subfamily 1 group I member 3 (NR1I3) OTS3SGH7 NR1I3_HUMAN Gene/Protein Processing [16]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1231).
2 Cimetidine FDA Label
3 Histamine H1 and H2 receptor antagonists accelerate skin barrier repair and prevent epidermal hyperplasia induced by barrier disruption in a dry environment. J Invest Dermatol. 2001 Feb;116(2):261-5.
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