Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMVNZ0)

Drug Name
Masoprocol Drug Info
Synonyms
NDGA; N 5023; TNP00263; Actinex (TN); Nordihydroguaiaretic acid (meso-form); (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol; 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
Indication
Disease Entry ICD 11 Status REF
Prostate cancer 2C82.0 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
71398
ChEBI ID
CHEBI:73468
CAS Number
CAS 27686-84-6
TTD Drug ID
DMMVNZ0

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Erbb2 tyrosine kinase receptor (HER2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [11]
Dacomitinib DMOH8VY Non-small-cell lung cancer 2C25.Y Approved [12]
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [13]
Merimepodib DM0HS92 Breast cancer 2C60-2C65 Approved [14]
NERATINIB MALEATE DMEDU7B HER2/NEU overexpressing breast cancer 2C60-2C65 Approved [15]
Margetuximab DMKEY6S HER2-positive breast cancer 2C60-2C65 Approved [16]
Trastuzumab DMZQOUX Breast cancer 2C60-2C65 Approved [17]
Tucatinib DMBESUA HER2-positive breast cancer 2C60-2C65 Approved [18]
Pertuzumab DMHJV0X Adrenal gland neoplasm Approved [19]
HKI-272 DM6QOVN Breast cancer 2C60-2C65 Phase 3 [20]
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Drug(s) Affected By Polyunsaturated fatty acid 5-lipoxygenase (ALOX5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [21]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [23]
Fructose DM43AN2 Vomiting MD90 Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [25]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [26]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [27]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [28]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [29]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [30]
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Drug(s) Affected By 11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [31]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [33]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [33]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [37]
Ethanol DMDRQZU Chronic pain MG30 Approved [38]
Oxymetholone DMFXUT8 Aplastic anemia 3A70 Approved [39]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [40]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [41]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [42]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [43]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [44]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [46]
Gefitinib DM15F0X Colon adenocarcinoma Approved [47]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [48]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [50]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [41]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [51]
Paclitaxel DMLB81S Breast carcinoma Approved [52]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [53]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [40]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [54]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [55]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [43]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [44]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [56]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [57]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [58]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [59]
Gefitinib DM15F0X Colon adenocarcinoma Approved [60]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [62]
Selenium DM25CGV N. A. N. A. Approved [63]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [64]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [65]
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Drug(s) Affected By Signal transducer and activator of transcription 3 (STAT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [54]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [55]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [66]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [67]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [68]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [69]
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [71]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [72]
Quercetin DM3NC4M Obesity 5B81 Approved [73]
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Drug(s) Affected By ALK tyrosine kinase receptor (ALK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ceritinib DMB920Z Non-small-cell lung cancer 2C25.Y Approved [74]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [77]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [78]
Arsenic DMTL2Y1 N. A. N. A. Approved [79]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [80]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [81]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [82]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [83]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [84]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [55]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [85]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [86]
Selenium DM25CGV N. A. N. A. Approved [87]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [83]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [88]
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [88]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [89]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [90]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [91]
Gefitinib DM15F0X Colon adenocarcinoma Approved [92]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [93]
Selenium DM25CGV N. A. N. A. Approved [94]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [65]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [95]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [96]
Methotrexate DM2TEOL Anterior urethra cancer Approved [97]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [98]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [99]
Fructose DM43AN2 Vomiting MD90 Approved [54]
Ketoprofen DMRKXPT Bursitis Approved [54]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [100]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [43]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [101]
Gefitinib DM15F0X Colon adenocarcinoma Approved [102]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [103]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [104]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [55]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [105]
Gefitinib DM15F0X Colon adenocarcinoma Approved [106]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [107]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [108]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [107]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [109]
Selenium DM25CGV N. A. N. A. Approved [110]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [111]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [112]
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Drug(s) Affected By Sex hormone-binding globulin (SHBG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Fructose DM43AN2 Vomiting MD90 Approved [115]
Oxcarbazepine DM5PU6O Epilepsy 8A60-8A68 Approved [116]
Estrone DM5T6US Acne vulgaris ED80 Approved [117]
Testosterone DM7HUNW Hot flushes GA30 Approved [118]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Dienestrol DMBSXI0 Atrophic vaginitis GA30.2 Approved [117]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [117]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [117]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [119]
Methotrexate DM2TEOL Anterior urethra cancer Approved [97]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [122]
Paclitaxel DMLB81S Breast carcinoma Approved [123]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [124]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [58]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [125]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [126]
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Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [127]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [128]
Fructose DM43AN2 Vomiting MD90 Approved [54]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [130]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [90]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [131]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [132]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [133]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
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Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [135]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Gefitinib DM15F0X Colon adenocarcinoma Approved [137]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [95]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [140]
Methotrexate DM2TEOL Anterior urethra cancer Approved [141]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [142]
Quercetin DM3NC4M Obesity 5B81 Approved [143]
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Drug(s) Affected By Insulin-like growth factor 1 receptor (IGF1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [144]
Gefitinib DM15F0X Colon adenocarcinoma Approved [145]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [64]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [146]
Quercetin DM3NC4M Obesity 5B81 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [148]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [149]
Testosterone DM7HUNW Hot flushes GA30 Approved [33]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [33]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [150]
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Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [153]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [154]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [155]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [158]
Panobinostat DM58WKG Chronic graft versus host disease Approved [159]
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Drug(s) Affected By Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [97]
Quercetin DM3NC4M Obesity 5B81 Approved [160]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [161]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [26]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [162]
Bortezomib DMNO38U Leukemia Approved [163]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [160]
BAICALEIN DM4C7E6 Influenza virus infection 1E30-1E32 Phase 2 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [164]
Milchsaure DM462BT Pruritus EC90 Investigative [165]
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Drug(s) Affected By fMet-Leu-Phe receptor (FPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [97]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [167]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Testosterone DM7HUNW Hot flushes GA30 Approved [33]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [171]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [172]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [173]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [174]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [175]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [59]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [176]
Gefitinib DM15F0X Colon adenocarcinoma Approved [177]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [178]
Selenium DM25CGV N. A. N. A. Approved [63]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [65]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [179]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [181]
Methotrexate DM2TEOL Anterior urethra cancer Approved [182]
Epinephrine DM3KJBC Acute asthma CA23 Approved [183]
Quercetin DM3NC4M Obesity 5B81 Approved [147]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [184]
Fructose DM43AN2 Vomiting MD90 Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [151]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [185]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [186]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [187]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [188]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [122]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [189]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [190]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [191]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [192]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [193]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [194]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [195]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [196]
Prednisone DM2HG4X Acute asthma CA23 Approved [197]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [198]
Quercetin DM3NC4M Obesity 5B81 Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [200]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [201]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [202]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [203]
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Drug(s) Affected By Type I iodothyronine deiodinase (DIO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [204]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [205]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [171]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [206]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [207]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [208]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [209]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [210]
Oxytetracycline DMOVH1M Actinomycosis Approved [211]
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Drug(s) Affected By Thyroxine 5-deiodinase (DIO3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [212]
Vemurafenib DM62UG5 Melanoma 2C30 Approved [213]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [214]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [27]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [207]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [212]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [212]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [215]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [212]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [216]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [217]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [218]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [219]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [220]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [221]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [222]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [181]
Meloxicam DM2AR7L Arthritis FA20 Approved [223]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [224]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [225]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [226]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [194]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [219]
Verapamil DMA7PEW Angina pectoris BA40 Approved [227]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [151]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [221]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Meloxicam DM2AR7L Arthritis FA20 Approved [228]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [230]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [231]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [232]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [55]
Gefitinib DM15F0X Colon adenocarcinoma Approved [233]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [234]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [181]
Selenium DM25CGV N. A. N. A. Approved [63]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [224]
Methotrexate DM2TEOL Anterior urethra cancer Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Type II iodothyronine deiodinase (DIO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [219]
Quercetin DM3NC4M Obesity 5B81 Approved [235]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [236]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [237]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [27]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [238]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [207]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [29]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [239]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Erbb2 tyrosine kinase receptor (HER2) TT6EO5L ERBB2_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Gene/Protein Processing [3]
ALK tyrosine kinase receptor (ALK) OTV3P4V8 ALK_HUMAN Gene/Protein Processing [4]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [5]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [7]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [8]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [5]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase inhibitor 2A (CDKN2A) OTN0ZWAE CDN2A_HUMAN Gene/Protein Processing [9]
fMet-Leu-Phe receptor (FPR1) OTFF9I6W FPR1_HUMAN Gene/Protein Processing [10]

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123 Gallic acid potentiates the apoptotic effect of paclitaxel and carboplatin via overexpression of Bax and P53 on the MCF-7 human breast cancer cell line. J Biochem Mol Toxicol. 2021 Feb;35(2):e22638. doi: 10.1002/jbt.22638. Epub 2020 Oct 1.
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