Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMNXYSM)

Drug Name
gingerol Drug Info
Synonyms [6]-Gingerol; 6-Gingerol
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
442793
ChEBI ID
CHEBI:10136
CAS Number
CAS 23513-14-6
TTD Drug ID
DMNXYSM

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Transformation-sensitive protein p120 (TRPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Menthol DMG2KW7 Back pain ME84.Z Approved [9]
LY3526318 DMFXNQM Chronic low-back pain MG30 Phase 2 [10]
HX-100 DMFRM15 Diabetic neuropathy 8C0Z Phase 1 [11]
NPPB DMFIWAN Discovery agent N.A. Investigative [12]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [13]
[3H]resolvin D1 DMFT0HU Discovery agent N.A. Investigative [14]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [15]
icilin DMYVOL9 Discovery agent N.A. Investigative [16]
4-oxo-nonenal DMPX1J9 Discovery agent N.A. Investigative [17]
dibutyl phthalate DMEDGKO Discovery agent N.A. Investigative [18]
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Drug(s) Affected By Prostaglandin E synthase (PTGES)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [19]
Selenium DM25CGV N. A. N. A. Approved [20]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [21]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [22]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [23]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Menthol DMG2KW7 Back pain ME84.Z Approved [25]
Mestranol DMG3F94 Contraception QA21 Approved [19]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [26]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [27]
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Drug(s) Affected By Apoptotic protease-activating factor 1 (APAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Quercetin DM3NC4M Obesity 5B81 Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [31]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [34]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [37]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [38]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [39]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [40]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [41]
Selenium DM25CGV N. A. N. A. Approved [42]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [38]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [43]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Gefitinib DM15F0X Colon adenocarcinoma Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [48]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [51]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [53]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [54]
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Drug(s) Affected By CASP8 and FADD-like apoptosis regulator (CFLAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [57]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [58]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [54]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [62]
Ethacrynic acid DM60QMR Edema MG29 Approved [63]
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Drug(s) Affected By Zinc finger protein SNAI2 (SNAI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Panobinostat DM58WKG Chronic graft versus host disease Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [67]
Leflunomide DMR8ONJ Arthritis FA20 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
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Drug(s) Affected By Serine/threonine-protein kinase LATS1 (LATS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [72]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [73]
Leflunomide DMR8ONJ Arthritis FA20 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [74]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [75]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [76]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [77]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [78]
Napabucasin DMDZ6Q3 Colorectal cancer 2B91.Z Phase 3 [79]
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Drug(s) Affected By Plasma kallikrein (KLKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [81]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [82]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Testosterone DM7HUNW Hot flushes GA30 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [84]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [85]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [84]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [81]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [87]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [88]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [89]
Paclitaxel DMLB81S Breast carcinoma Approved [90]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [91]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [92]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [93]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [94]
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Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [95]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [96]
Gefitinib DM15F0X Colon adenocarcinoma Approved [97]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [100]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [101]
Methotrexate DM2TEOL Anterior urethra cancer Approved [102]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [103]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
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Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [106]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Selenium DM25CGV N. A. N. A. Approved [108]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [109]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
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Drug(s) Affected By 72 kDa type IV collagenase (MMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [111]
Selenium DM25CGV N. A. N. A. Approved [112]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [115]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [116]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [117]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [118]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [119]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [120]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [121]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [122]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [123]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [124]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [80]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [125]
Verapamil DMA7PEW Angina pectoris BA40 Approved [126]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [127]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [128]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [129]
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Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [130]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [131]
Selenium DM25CGV N. A. N. A. Approved [108]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [132]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [133]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [135]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [31]
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Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [106]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Selenium DM25CGV N. A. N. A. Approved [108]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [137]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [138]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
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Drug(s) Affected By Matrix metalloproteinase-9 (MMP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [141]
Gefitinib DM15F0X Colon adenocarcinoma Approved [142]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [143]
Selenium DM25CGV N. A. N. A. Approved [112]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [144]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [145]
Methotrexate DM2TEOL Anterior urethra cancer Approved [57]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [146]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [147]
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Drug(s) Affected By Ribosomal protein S6 kinase beta-1 (RPS6KB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [148]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [149]
Gefitinib DM15F0X Colon adenocarcinoma Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [151]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [100]
Quercetin DM3NC4M Obesity 5B81 Approved [152]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [156]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [157]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [158]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [129]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [159]
Gefitinib DM15F0X Colon adenocarcinoma Approved [160]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Selenium DM25CGV N. A. N. A. Approved [20]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [162]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [163]
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Drug(s) Affected By G1/S-specific cyclin-E1 (CCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [125]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [164]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [165]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [137]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [101]
Quercetin DM3NC4M Obesity 5B81 Approved [166]
Fluoxetine DM3PD2C Bipolar depression Approved [167]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [168]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [169]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [170]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [171]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [173]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [116]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [175]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [176]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [178]
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Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [179]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [180]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [181]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [182]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [183]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [184]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [185]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [141]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [186]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [187]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [188]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [189]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Gefitinib DM15F0X Colon adenocarcinoma Approved [46]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Etretinate DM2CZFA Keratosis ED56 Approved [49]
Prednisone DM2HG4X Acute asthma CA23 Approved [191]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [137]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [38]
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Drug(s) Affected By Serine/threonine-protein kinase mTOR (MTOR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [192]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [149]
Gefitinib DM15F0X Colon adenocarcinoma Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [194]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [162]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [196]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [197]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [198]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [199]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [200]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [89]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [201]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [202]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [203]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [204]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [205]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [206]
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Drug(s) Affected By 5-hydroxytryptamine receptor 3A (HTR3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [207]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [208]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [209]
Metoclopramide DMFA5MY Nausea MD90 Approved [210]
Capsaicin DMGMF6V Back pain ME84.Z Approved [3]
Hydromorphone DMHP21E Back pain ME84.Z Approved [211]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [82]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [208]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [207]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [96]
Gefitinib DM15F0X Colon adenocarcinoma Approved [160]
Prednisone DM2HG4X Acute asthma CA23 Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [212]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [213]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [214]
Quercetin DM3NC4M Obesity 5B81 Approved [215]
Fluoxetine DM3PD2C Bipolar depression Approved [167]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [216]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [217]
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Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [218]
Gefitinib DM15F0X Colon adenocarcinoma Approved [97]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [219]
Selenium DM25CGV N. A. N. A. Approved [20]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [220]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [221]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [222]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [31]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [223]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 10 (TNFSF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [40]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [55]
Selenium DM25CGV N. A. N. A. Approved [20]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [224]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [225]
Methotrexate DM2TEOL Anterior urethra cancer Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [166]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [226]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [227]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [229]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [230]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [125]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [127]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [231]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [48]
Meloxicam DM2AR7L Arthritis FA20 Approved [233]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [234]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [235]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BH3-interacting domain death agonist (BID)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [48]
Selenium DM25CGV N. A. N. A. Approved [42]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [236]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [237]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [238]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [239]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [240]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [84]
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Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [129]
Selenium DM25CGV N. A. N. A. Approved [20]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [109]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [21]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [241]
Quercetin DM3NC4M Obesity 5B81 Approved [166]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [242]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [243]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [121]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [206]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [125]
Verapamil DMA7PEW Angina pectoris BA40 Approved [126]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [55]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [231]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Meloxicam DM2AR7L Arthritis FA20 Approved [244]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [137]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [245]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [246]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [247]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Gefitinib DM15F0X Colon adenocarcinoma Approved [248]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [249]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [48]
Selenium DM25CGV N. A. N. A. Approved [20]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [234]
Methotrexate DM2TEOL Anterior urethra cancer Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth/differentiation factor 15 (GDF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [250]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [38]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [30]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [251]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [252]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [253]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 10 (DUSP10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [255]
Methotrexate DM2TEOL Anterior urethra cancer Approved [256]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [257]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [252]
Panobinostat DM58WKG Chronic graft versus host disease Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [257]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [258]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [259]
Leflunomide DMR8ONJ Arthritis FA20 Approved [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [260]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [261]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [262]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [263]
Capsaicin DMGMF6V Back pain ME84.Z Approved [264]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [265]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [266]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [265]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [261]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [80]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Transformation-sensitive protein p120 (TRPA1) TTELV3W TRPA1_HUMAN Activator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5-hydroxytryptamine receptor 3A (HTR3A) OTAIV1AK 5HT3A_HUMAN Gene/Protein Processing [3]
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [4]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [5]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [5]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Gene/Protein Processing [5]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [6]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Gene/Protein Processing [7]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Gene/Protein Processing [7]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [5]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Protein Interaction/Cellular Processes [8]

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87 Azidothymidine and cisplatin increase p14ARF expression in OVCAR-3 ovarian cancer cell line. Toxicol Appl Pharmacol. 2006 Oct 1;216(1):89-97. doi: 10.1016/j.taap.2006.04.015. Epub 2006 May 19.
88 Quantitative analysis of gene expression changes in response to genotoxic compounds. Toxicol In Vitro. 2017 Mar;39:15-28. doi: 10.1016/j.tiv.2016.11.004. Epub 2016 Nov 5.
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92 Role of miRNA in the regulation of cannabidiol-mediated apoptosis in neuroblastoma cells. Oncotarget. 2019 Jan 1;10(1):45-59. doi: 10.18632/oncotarget.26534. eCollection 2019 Jan 1.
93 Nitrogen Mustard Alkylates and Cross-Links p53 in Human Keratinocytes. Chem Res Toxicol. 2022 Apr 18;35(4):636-650. doi: 10.1021/acs.chemrestox.1c00420. Epub 2022 Mar 21.
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