General Information of Drug (ID: DMOSW35)

Drug Name
Felodipine Drug Info
Synonyms
Agon; Felobeta; Felocor; Feloday; Felodipina; Felodipinum; Felodur; Felogamma; Felogard; Fensel; Flodil; Hydac; Lexxel; Logimax; Modip; Munobal; Penedil; Perfudal; Plandil; Plendil; Preslow; Prevex; Renedil; Splendil; AGON SR; AbZ Brand of Felodipine; Aliud Brand of Felodipine; Alphapharm Brand of Felodipine; Alpharma Brand of Felodipine; Astra Brand of Felodipine; AstraZeneca Brand of Felodipine; Aventis Brand of Felodipine; Azupharma Brand of Felodipine; BC Brand of Felodipine; Betapharm Brand of Felodipine; Ct Arzneimittel Brand of Felodipine; Felo Biochemie; Felo Puren; Felodipin AL; Felodipin AZU; Felodipin AbZ; Felodipin Heumann; Felodipin Stada; Felodipin dura; Felodipin ratiopharm; Felodipin von ct; FelodurER; Heumann Brand of Felodipine; Hexal Brand of Felodipine; Hoechst Brand of Felodipine; Merck dura Brand of Felodipine; Munobal Retard; Pharmaceutica Astra Brand of Felodipine; Pharmacia Spain Brandof Felodipine; Plendil Depottab; Plendil ER; Plendil Retard; Promed Brand of Felodipine; Ratiopharm Brand of Felodipine; Stadapharm Brand of Felodipine; TheraPharm Brand of Felodipine; Worwag Brand of Felodipine; F 9677; Felodipin 1A Pharma; H 154 82; H 15482; CGH-869; Ct-Arzneimittel Brand of Felodipine; Dl-Felodipine; Felo-Puren; Felodipin-ratiopharm; Felodipina [INN-Spanish]; Felodipinum [INN-Latin]; H 154-82; H 154/82; Heumann, Felodipin; Plendil (TN); AE-641/11429675; Felodipine [USAN:BAN:INN]; Felodipine [USAN:INN:BAN]; H-154/82; Felodipine (JAN/USP/INN); Plendil, Renedil, Feloday, Felodipine; Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; (+-)-Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate; (+/-)-ethylmethyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate; 1A Brand of Felodipine; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-, ethyl methylester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-,ethyl methyl ester; 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester; 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate; 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester; 4-(2,3-dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester; 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester; 5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Indication
Disease Entry ICD 11 Status REF
Hypertension BA00-BA04 Approved [1]
Therapeutic Class
Antihypertensive Agents
Cross-matching ID
PubChem CID
3333
ChEBI ID
CHEBI:585948
CAS Number
CAS 72509-76-3
TTD Drug ID
DMOSW35
VARIDT Drug ID
DR00691
INTEDE Drug ID
DR0685
ACDINA Drug ID
D00267

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nicardipine DMCDYW7 High blood pressure BA00 Approved [11]
Clevidipine butyrate DMW4M97 Hypertension BA00-BA04 Approved [12]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [13]
Nimodipine DMQ0RKZ Cerebral vasospasm BA85.Z Approved [14]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [15]
Isradipine DMA5XGH Hypertension BA00-BA04 Approved [15]
DIPROTEVERINE HYDROCHLORIDE DMG8U6M Angina pectoris BA40 Phase 3 [16]
ATI-2042 DMWP59B Atrial fibrillation BC81.3 Phase 2 [17]
HBI-3000 DM74ZKN Heart arrhythmia BC65 Phase 2 [18]
Nexopamil DML5S71 Hypertension BA00-BA04 Phase 2 [19]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [20]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [22]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [24]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [22]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [25]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [26]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [27]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [28]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [29]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [30]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [31]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [32]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [33]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [34]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [28]
Verapamil DMA7PEW Angina pectoris BA40 Approved [35]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [48]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [49]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [50]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [51]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [52]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [52]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [53]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [54]
Capsaicin DMGMF6V Back pain ME84.Z Approved [55]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [56]
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Drug(s) Metabolized By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [36]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [37]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [38]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [5]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [39]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [40]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [41]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [42]
Verapamil DMA7PEW Angina pectoris BA40 Approved [43]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [5]
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Drug(s) Metabolized By Cytochrome P450 3A7 (CYP3A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [44]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [5]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [5]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [5]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [45]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [5]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [5]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [5]
Metronidazole DMTIVEN Abscess Approved [47]
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Drug(s) Affected By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [57]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [58]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [57]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [58]
Sulfinpyrazone DMEV954 Gout FA25 Approved [59]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [57]
Zafirlukast DMHNQOG Asthma CA23 Approved [57]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [57]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [60]
Dabrafenib DMX6OE3 Melanoma 2C30 Approved [61]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [62]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [9]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [9]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [63]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [62]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [9]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [64]
Gefitinib DM15F0X Colon adenocarcinoma Approved [62]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [65]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [62]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [66]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [66]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [67]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [68]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [69]
Etidronic acid DM1XHYJ Bone Paget disease Approved [66]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [66]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [66]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [70]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [71]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [72]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [10]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [73]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [74]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [75]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [76]
Ethacrynic acid DM60QMR Edema MG29 Approved [77]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [78]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [79]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [80]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [81]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [81]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [81]
Capsaicin DMGMF6V Back pain ME84.Z Approved [82]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [83]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [84]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [85]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [86]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [87]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [88]
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Drug(s) Affected By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tegafur DM31ZQM Solid tumour/cancer 2A00-2F9Z Approved [89]
Methoxsalen DME8FZ9 Cutaneous T-cell lymphoma 2B01 Approved [90]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [93]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [30]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [96]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [97]
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Drug(s) Affected By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [49]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [98]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [52]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [51]
Capsaicin DMGMF6V Back pain ME84.Z Approved [82]
Zafirlukast DMHNQOG Asthma CA23 Approved [99]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [52]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [100]
Fluconazole DMOWZ6B Cryptococcal meningitis Approved [51]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [52]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [101]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [102]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [103]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [104]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [105]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [106]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [107]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [108]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [109]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [110]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [112]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [113]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [114]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [117]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [119]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [120]
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Drug(s) Affected By Cytochrome P450 2J2 (CYP2J2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [125]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [121]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [127]
Gemfibrozil DMD8Q3J Hyperlipidaemia 5C80 Approved [128]
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Drug(s) Affected By Aurora kinase A (AURKA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [129]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [131]
Methotrexate DM2TEOL Anterior urethra cancer Approved [132]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [131]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
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Drug(s) Affected By Natriuretic peptides A (NPPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [137]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [138]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [140]
Cilazapril DM4V6JA Congestive heart failure BD10 Approved [141]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [142]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [143]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [145]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [146]
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Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [147]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Gefitinib DM15F0X Colon adenocarcinoma Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [151]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [150]
Estrone DM5T6US Acne vulgaris ED80 Approved [155]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Androgen receptor (AR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [156]
Nilutamide DMFN07X Prostate cancer 2C82.0 Approved [156]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [156]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [157]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [158]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [159]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [160]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [6]
Selenium DM25CGV N. A. N. A. Approved [161]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [166]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [167]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [168]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [170]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [171]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [172]
Estrone DM5T6US Acne vulgaris ED80 Approved [173]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [174]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [175]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [176]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [177]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [178]
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Drug(s) Affected By Bile acid receptor (NR1H4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [179]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [6]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [180]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [181]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [182]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [6]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [180]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [183]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcium channel unspecific (CaC) TT5HONZ NOUNIPROTAC Blocker [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [4]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Substrate [5]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Gene/Protein Processing [6]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Gene/Protein Processing [7]
Aurora kinase A (AURKA) OTMX0HYT AURKA_HUMAN Protein Interaction/Cellular Processes [8]
Bile acid receptor (NR1H4) OTWZLPTB NR1H4_HUMAN Gene/Protein Processing [6]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [9]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [7]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Gene/Protein Processing [7]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Gene/Protein Processing [10]
Cytochrome P450 2A6 (CYP2A6) OT52TWG3 CP2A6_HUMAN Gene/Protein Processing [7]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Gene/Protein Processing [7]

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