General Information of Drug (ID: DMPDW6T)

Drug Name
Epirubicin Drug Info
Synonyms
Ellence; Epiadriamycin; Epidoxorubicin; Epirubicina; Epirubicine; Epirubicinum; Pidorubicin; Pidorubicina; Pidorubicine; Pidorubicinum; Ridorubicin; Epirubicina [Spanish]; Epirubicine [French]; Epirubicinum [Latin]; Pharmorubicin Pfs; IMI 28; WP 697; Ebewe (TN); Ellence (TN); Epi-DX; Epirubicin (INN); Epirubicin (TN); Epirubicin [INN:BAN]; Epirubicina [INN-Spanish]; Epirubicine [INN-French]; Epirubicinum [INN-Latin]; Farmorubicin (TN); Pharmorubicin (TN); Pidorubicina [INN-Spanish]; Pidorubicine [INN-French]; Pidorubicinum [INN-Latin]; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranoside; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranoside; (7S,9R)-7-[(2S,4S,5R,6S)-4-Amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; (7S,9S)-7-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; 10-((3-amino-2,3,6-trideoxy-beta-L-arabino-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-(8S-cis)-5,12-naphthacenedione; 4'-Epi-DXR; 4'-Epiadriamycin; 4'-epi-DX; 4'-epi-Doxorubicin; 4'-epidoxorubicin; 4-Epidoxorubicin
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
41867
ChEBI ID
CHEBI:47898
CAS Number
CAS 56420-45-2
TTD Drug ID
DMPDW6T
VARIDT Drug ID
DR00170
INTEDE Drug ID
DR0591

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Drug(s) Targeting DNA topoisomerase II (TOP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [2]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [13]
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [2]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [14]
Idarubicin DMM0XGL Acute myelogenous leukaemia 2A41 Approved [2]
Lomefloxacin DMVRH9C Bacterial infection 1A00-1C4Z Approved [15]
Dexrazoxane DMD7X1O Breast cancer 2C60-2C65 Approved [2]
Podofilox DMT2EJP Condyloma 1A95 Approved [16]
Enoxacin DMYTE6L Acute gonococcal cervicitis Approved [17]
Amsacrine DMZKYIV Acute lymphoblastic leukaemia 2A85 Approved [18]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [20]
Folic Acid DMEMBJC Colorectal carcinoma Approved [21]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [23]
Verapamil DMA7PEW Angina pectoris BA40 Approved [24]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [25]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [26]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [27]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [28]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [72]
Folic Acid DMEMBJC Colorectal carcinoma Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [73]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [74]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [75]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [76]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [77]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [77]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [78]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Folic Acid DMEMBJC Colorectal carcinoma Approved [31]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [32]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [33]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [34]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [35]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [36]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [37]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [38]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [24]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [39]
Methotrexate DM2TEOL Anterior urethra cancer Approved [3]
Folic Acid DMEMBJC Colorectal carcinoma Approved [40]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [3]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [3]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [41]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [3]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [42]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [43]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Methotrexate DM2TEOL Anterior urethra cancer Approved [45]
Folic Acid DMEMBJC Colorectal carcinoma Approved [46]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [47]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [48]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [49]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [50]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [49]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [51]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [52]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [53]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [54]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [55]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [57]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [55]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [58]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [59]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [60]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [61]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Lopinavir DMITQS0 Human immunodeficiency virus infection 1C62 Approved [62]
Sulfinpyrazone DMEV954 Gout FA25 Approved [63]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [64]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [65]
Methotrexate DM2TEOL Anterior urethra cancer Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [67]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [68]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [69]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [70]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [71]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [79]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [80]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [81]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [82]
Cepharanthine DM9Y5JB N. A. N. A. Approved [83]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [84]
Clozapine DMFC71L Schizophrenia 6A20 Approved [85]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [86]
Trifluoperazine DMKBYWI Anxiety Approved [87]
Olanzapine DMPFN6Y Bipolar depression Approved [85]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [88]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [88]
Gefitinib DM15F0X Colon adenocarcinoma Approved [89]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [90]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [91]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [92]
Methotrexate DM2TEOL Anterior urethra cancer Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [94]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [95]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [96]
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Drug(s) Affected By Natriuretic peptides A (NPPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [97]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [98]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Cilazapril DM4V6JA Congestive heart failure BD10 Approved [101]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [102]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [103]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [104]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [105]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [106]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [107]
Methotrexate DM2TEOL Anterior urethra cancer Approved [108]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [109]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [110]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [111]
Paclitaxel DMLB81S Breast carcinoma Approved [112]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [113]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [114]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [115]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [116]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [117]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [118]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [120]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [121]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [122]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [124]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [125]
Methotrexate DM2TEOL Anterior urethra cancer Approved [117]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [126]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [127]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [129]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [130]
Testosterone enanthate DMB6871 N. A. N. A. Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [132]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [133]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [134]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [135]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [136]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [138]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [139]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [139]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [139]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [139]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [141]
Ethanol DMDRQZU Chronic pain MG30 Approved [142]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [143]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [144]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [145]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [146]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [90]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Verapamil DMA7PEW Angina pectoris BA40 Approved [147]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [148]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [149]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [150]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [151]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [152]
Gefitinib DM15F0X Colon adenocarcinoma Approved [153]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [154]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [155]
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [157]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [158]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [159]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [160]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [162]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [149]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [164]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [165]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [166]
Gefitinib DM15F0X Colon adenocarcinoma Approved [167]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [168]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [169]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [170]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [162]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [171]
Paclitaxel DMLB81S Breast carcinoma Approved [172]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [173]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [90]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [149]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [164]
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Drug(s) Affected By Protein PML (PML)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [175]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [176]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [177]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [178]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [105]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [179]
Menthol DMG2KW7 Back pain ME84.Z Approved [180]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [182]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [183]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [184]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [185]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [111]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [186]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [187]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [189]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [190]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [191]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [192]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [193]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [148]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [194]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [196]
Meloxicam DM2AR7L Arthritis FA20 Approved [197]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [198]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [199]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [143]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [191]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Verapamil DMA7PEW Angina pectoris BA40 Approved [147]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [136]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [194]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [200]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [201]
Meloxicam DM2AR7L Arthritis FA20 Approved [202]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [203]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [205]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [206]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [207]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [208]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [209]
Testosterone DM7HUNW Hot flushes GA30 Approved [210]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [211]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [130]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [212]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [12]
Leflunomide DMR8ONJ Arthritis FA20 Approved [213]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [214]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [215]
Arsenic DMTL2Y1 N. A. N. A. Approved [216]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [12]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [217]
Urethane DM7NSI0 N. A. N. A. Phase 4 [218]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [219]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [220]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [90]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [221]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [222]
Methotrexate DM2TEOL Anterior urethra cancer Approved [223]
Quercetin DM3NC4M Obesity 5B81 Approved [224]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [226]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [227]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [228]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [229]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [182]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [230]
Gefitinib DM15F0X Colon adenocarcinoma Approved [231]
Paclitaxel DMLB81S Breast carcinoma Approved [231]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [232]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [230]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [233]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [234]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [234]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [235]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [130]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [236]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [179]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [237]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [238]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [182]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [239]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [130]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-protein kinase 1 (ALPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [240]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [241]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [242]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [239]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [243]
Streptozocin DMOF7AT Pancreatic cancer 2C10 Approved [244]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [245]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [219]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [179]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [246]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [214]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [215]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [70]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [247]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [248]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [10]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [249]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [250]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [251]
Gefitinib DM15F0X Colon adenocarcinoma Approved [252]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [253]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [196]
Etretinate DM2CZFA Keratosis ED56 Approved [254]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [255]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [256]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [257]
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [259]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [260]
Selenium DM25CGV N. A. N. A. Approved [261]
Methotrexate DM2TEOL Anterior urethra cancer Approved [117]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [262]
Epinephrine DM3KJBC Acute asthma CA23 Approved [263]
Quercetin DM3NC4M Obesity 5B81 Approved [264]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [177]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [127]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [265]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [178]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-P (S100P)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [266]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [267]
Quercetin DM3NC4M Obesity 5B81 Approved [268]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [178]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [269]
Estrone DM5T6US Acne vulgaris ED80 Approved [270]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [209]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [271]
Testosterone DM7HUNW Hot flushes GA30 Approved [272]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [235]
Quercetin DM3NC4M Obesity 5B81 Approved [273]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [274]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [275]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [269]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [276]
Panobinostat DM58WKG Chronic graft versus host disease Approved [245]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [277]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [130]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [250]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [158]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [130]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [215]
Arsenic DMTL2Y1 N. A. N. A. Approved [216]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [278]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [158]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [219]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [233]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microcephalin (MCPH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [223]
Testosterone DM7HUNW Hot flushes GA30 Approved [279]
Leflunomide DMR8ONJ Arthritis FA20 Approved [213]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [280]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [281]
Arsenic DMTL2Y1 N. A. N. A. Approved [216]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [282]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [283]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [239]
Urethane DM7NSI0 N. A. N. A. Phase 4 [218]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA topoisomerase II (TOP2) TT0IHXV TOP2A_HUMAN; TOP2B_HUMAN Modulator [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [3]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [4]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [3]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 2B7 (UGT2B7) Main DME DEB3CV1 UD2B7_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-protein kinase 1 (ALPK1) OTBW6SGD ALPK1_HUMAN Drug Response [6]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [7]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [8]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Gene/Protein Processing [8]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [8]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Drug Response [9]
Baculoviral IAP repeat-containing protein 6 (BIRC6) OTCQJAB0 BIRC6_HUMAN Drug Response [10]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Drug Response [11]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [12]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [7]

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