General Information of Drug (ID: DMPTY8S)

Drug Name
Aloe-emodin Drug Info
Synonyms
Aloe-emodin; Aloe emodin; 481-72-1; Aloeemodin; Aloe-emodine; Rhabarberone; EMODINE; 3-Hydroxymethylchrysazin; 1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione; 3-Hydroxymethylchrysazine; 1,8-Dihydroxy-3-hydroxymethylanthraquinone; 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone; NSC 38628; 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione; UNII-C8IYT9CR7C; 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-; CCRIS 3526; EINECS 207-571-7; C8IYT9CR7C; 3-(Hydroxymethyl)chrysazin; BRN 2059062; CHEMBL40275; CHEBI:2607
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10207
ChEBI ID
CHEBI:2607
CAS Number
CAS 481-72-1
TTD Drug ID
DMPTY8S

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [6]
NPS 1776 DM0CF3B Epilepsy 8A60-8A68 Discontinued in Phase 2 [7]
NSC-527035 DMY689Z Discovery agent N.A. Investigative [8]
S-methyl 4-methyl-4-morpholinopent-2-ynethioate DM79QC2 Discovery agent N.A. Investigative [9]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [12]
Methotrexate DM2TEOL Anterior urethra cancer Approved [10]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Folic Acid DMEMBJC Colorectal carcinoma Approved [10]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [16]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [17]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [18]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [19]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [20]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [21]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [22]
Ethacrynic acid DM60QMR Edema MG29 Approved [23]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [24]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [25]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [26]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [27]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [27]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [27]
Capsaicin DMGMF6V Back pain ME84.Z Approved [28]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [29]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [30]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [31]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [32]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [33]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [34]
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Drug(s) Affected By Sulfotransferase 1E1 (SULT1E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [35]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Methotrexate DM2TEOL Anterior urethra cancer Approved [36]
Estrone DM5T6US Acne vulgaris ED80 Approved [37]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [35]
Dienestrol DMBSXI0 Atrophic vaginitis GA30.2 Approved [37]
Ethanol DMDRQZU Chronic pain MG30 Approved [38]
Folic Acid DMEMBJC Colorectal carcinoma Approved [39]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [40]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [41]
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Drug(s) Affected By Sulfotransferase 1A1 (SULT1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [42]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [43]
Minoxidil DMA2Z4F Alopecia ED70 Approved [44]
Benzyl alcohol DMBVYDI Head and body lice 1G00.0 Approved [45]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [44]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [35]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Methotrexate DM2TEOL Anterior urethra cancer Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [48]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [18]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [51]
Estrone DM5T6US Acne vulgaris ED80 Approved [52]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [53]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [54]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [55]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [56]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [57]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [58]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [60]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [61]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [62]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [63]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [64]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [65]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [66]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [67]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [68]
Fructose DM43AN2 Vomiting MD90 Approved [34]
Ketoprofen DMRKXPT Bursitis Approved [34]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [69]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [70]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [71]
Gefitinib DM15F0X Colon adenocarcinoma Approved [72]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [73]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [76]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [78]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [79]
Paclitaxel DMLB81S Breast carcinoma Approved [80]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [81]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [82]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [83]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [84]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [85]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [86]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [88]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [91]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [92]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [94]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [95]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [96]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [97]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [34]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [98]
Verapamil DMA7PEW Angina pectoris BA40 Approved [99]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [100]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [70]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [101]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [103]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [104]
Etretinate DM2CZFA Keratosis ED56 Approved [105]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [106]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [107]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [108]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [109]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [110]
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Drug(s) Affected By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [111]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [112]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [113]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [114]
Capsaicin DMGMF6V Back pain ME84.Z Approved [28]
Zafirlukast DMHNQOG Asthma CA23 Approved [115]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [113]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [116]
Fluconazole DMOWZ6B Cryptococcal meningitis Approved [114]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [113]
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Drug(s) Affected By Carbonyl reductase 1 (CBR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Testosterone enanthate DMB6871 N. A. N. A. Approved [118]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [119]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [120]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [121]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [122]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [123]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [121]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [124]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [125]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [127]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [60]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [48]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [129]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [34]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [130]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [131]
Methotrexate DM2TEOL Anterior urethra cancer Approved [132]
Quercetin DM3NC4M Obesity 5B81 Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [129]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [136]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [137]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [139]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [140]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [141]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [137]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [142]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [143]
Ethanol DMDRQZU Chronic pain MG30 Approved [144]
Menthol DMG2KW7 Back pain ME84.Z Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [146]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [147]
Methotrexate DM2TEOL Anterior urethra cancer Approved [148]
Epinephrine DM3KJBC Acute asthma CA23 Approved [149]
Quercetin DM3NC4M Obesity 5B81 Approved [150]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
Fructose DM43AN2 Vomiting MD90 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [146]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [153]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [111]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [154]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [114]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [155]
Capsaicin DMGMF6V Back pain ME84.Z Approved [28]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [113]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [30]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [113]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [154]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [34]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [124]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [156]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [85]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [157]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [103]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [106]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [158]
Methotrexate DM2TEOL Anterior urethra cancer Approved [159]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [160]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [161]
Diazepam DM08E9O Alcohol withdrawal Approved [162]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [163]
Desogestrel DM27U4Y Contraception QA21 Approved [163]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [161]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [161]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [167]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [168]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [169]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [79]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [170]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [171]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [173]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [174]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [175]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [176]
Gefitinib DM15F0X Colon adenocarcinoma Approved [177]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [178]
Epinephrine DM3KJBC Acute asthma CA23 Approved [149]
Quercetin DM3NC4M Obesity 5B81 Approved [179]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [22]
Fructose DM43AN2 Vomiting MD90 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [180]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [181]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [182]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [183]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [184]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [98]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [100]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [147]
Meloxicam DM2AR7L Arthritis FA20 Approved [187]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [188]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [189]
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Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [190]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [191]
Gefitinib DM15F0X Colon adenocarcinoma Approved [192]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [104]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [193]
Methotrexate DM2TEOL Anterior urethra cancer Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [194]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [195]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [94]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [175]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [98]
Verapamil DMA7PEW Angina pectoris BA40 Approved [99]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [146]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [185]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [196]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [197]
Meloxicam DM2AR7L Arthritis FA20 Approved [198]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [199]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [200]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [201]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [202]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [190]
Gefitinib DM15F0X Colon adenocarcinoma Approved [177]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [203]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [147]
Selenium DM25CGV N. A. N. A. Approved [204]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [188]
Methotrexate DM2TEOL Anterior urethra cancer Approved [76]
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Drug(s) Affected By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [155]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [205]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [206]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [207]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [208]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [209]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [210]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [211]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [212]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [213]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [214]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [111]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [215]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [114]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [113]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [216]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [217]
Capsaicin DMGMF6V Back pain ME84.Z Approved [218]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [219]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty aldehyde dehydrogenase (ALDH3A2) TTB6UM0 AL3A2_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [2]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Gene/Protein Processing [2]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [3]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [4]
Arylamine N-acetyltransferase 1 (NAT1) OTCCNQ3H ARY1_HUMAN Gene/Protein Processing [5]
Carbonyl reductase 1 (CBR1) OTQ3A541 CBR1_HUMAN Gene/Protein Processing [2]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [3]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [3]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [3]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [3]

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114 The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp., and Microsporum canis. Antimicrob Agents Chemother. 2004 Sep;48(9):3272-8.
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121 Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNF-mediated hepatotoxicity. Toxicol Sci. 2014 Jul;140(1):144-59. doi: 10.1093/toxsci/kfu072. Epub 2014 Apr 20.
122 Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: application to acetaminophen injury. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):270-80.
123 Proteomic analysis of hepatic effects of phenobarbital in mice with humanized liver. Arch Toxicol. 2022 Oct;96(10):2739-2754. doi: 10.1007/s00204-022-03338-7. Epub 2022 Jul 26.
124 Inhibiting Heat Shock Proteins Can Potentiate the Cytotoxic Effect of Cannabidiol in Human Glioma Cells. Anticancer Res. 2015 Nov;35(11):5827-37.
125 Expression profile analysis of colon cancer cells in response to sulindac or aspirin. Biochem Biophys Res Commun. 2002 Mar 29;292(2):498-512.
126 Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
127 Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells. Cancer Sci. 2007 Jun;98(6):890-9.
128 Identification of novel activators of the metal responsive transcription factor (MTF-1) using a gene expression biomarker in a microarray compendium. Metallomics. 2020 Sep 23;12(9):1400-1415. doi: 10.1039/d0mt00071j.
129 Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines. Cancer Res. 2005 Dec 15;65(24):11676-88.
130 Transcriptomic Analysis of Stem Cells Treated with Moringin or Cannabidiol: Analogies and Differences in Inflammation Pathways. Int J Mol Sci. 2019 Nov 30;20(23):6039. doi: 10.3390/ijms20236039.
131 Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation. J Biol Chem. 2005 Jan 28;280(4):2912-23. doi: 10.1074/jbc.M409524200. Epub 2004 Nov 17.
132 Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium. Arthritis Rheumatol. 2014 Jan;66(1):15-23.
133 Quercetin potentiates apoptosis by inhibiting nuclear factor-kappaB signaling in H460 lung cancer cells. Biol Pharm Bull. 2013;36(6):944-51. doi: 10.1248/bpb.b12-01004.
134 Suppression of mammary carcinoma growth by retinoic acid: proapoptotic genes are targets for retinoic acid receptor and cellular retinoic acid-binding protein II signaling. Cancer Res. 2005 Sep 15;65(18):8193-9. doi: 10.1158/0008-5472.CAN-05-1177.
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