Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMR1NMD)

Drug Name
Nimesulide Drug Info
Synonyms
nimesulide; 51803-78-2; N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide; Mesulid; Flogovital; Sulidene; Nimed; R-805; 4-NITRO-2-PHENOXYMETHANESULFONANILIDE; Nisulid; Nimesulidum [INN-Latin]; Nimesulida [INN-Spanish]; R 805; UNII-V4TKW1454M; 4-Nitro-2-phenoxy-methanesulfonanilide; 4'-Nitro-2'-phenoxymethanesulfonanilide; Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)-; EINECS 257-431-4; 4'-Nitro-2'-phenoxymethansulfonanilid; BRN 2421175; CHEMBL56367; MLS000069680; V4TKW1454M; Methanesulfonanilide, 4'-nitro-2'-phenoxy-; CHEBI:44445; Dulanermin
Indication
Disease Entry ICD 11 Status REF
Metastatic colorectal cancer 2B91 Terminated [1]
Non-hodgkin lymphoma 2B33.5 Terminated [1]
Non-small-cell lung cancer 2C25.Y Terminated [1]
Cross-matching ID
PubChem CID
4495
ChEBI ID
CHEMBL44445
CAS Number
CAS 51803-78-2
TTD Drug ID
DMR1NMD
INTEDE Drug ID
DR1160

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Clinical Trial Drug(s)
Approved Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting TNF related apoptosis inducing ligand (TNFSF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ad5-TRAIL DM2UMGE Prostate cancer 2C82.0 Phase 1 [14]
DA-3607 DM4JG0B Brain cancer 2A00 Phase 1 [15]
ABBV-621 DM90EO3 Haematological malignancy 2B33.Y Phase 1 [16]
Drug(s) Targeting Prostaglandin G/H synthase 2 (COX-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [17]
Naproxen DMZ5RGV Bursitis Approved [18]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [19]
Indomethacin DMSC4A7 Bursitis Approved [3]
Celecoxib DM6LOQU Dysmenorrhea GA34.3 Approved [20]
Nabumetone DMAT2XH Osteoarthritis FA00-FA05 Approved [21]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [22]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [23]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [24]
Aminosalicylic Acid DMENSL5 Crohn disease DD70 Approved [3]
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Drug(s) Targeting Lactotransferrin (LTF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Parecoxib DMIV8CT N. A. N. A. Phase 4 [25]
Talactoferrin DMV7T64 Diabetic foot ulcer BD54 Phase 3 [26]
HLF 1-11 DMDFG1O Bacteremia 1A73 Phase 1/2 [27]
Alpha-D-Mannose DMF5DLW Discovery agent N.A. Investigative [28]
Fucose DMAHMSV N. A. N. A. Investigative [28]
Lauric Acid DM9C8KQ Discovery agent N.A. Investigative [28]
Alpha-D-Fucose DM6VH7A Discovery agent N.A. Investigative [28]
Nitrilotriacetic Acid DMIOQFU Discovery agent N.A. Investigative [28]
3h-Indole-5,6-Diol DMBFCTZ Discovery agent N.A. Investigative [28]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [29]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [30]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [31]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [33]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [34]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [35]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [36]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [30]
Verapamil DMA7PEW Angina pectoris BA40 Approved [37]
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Drug(s) Affected By Proepiregulin (EREG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [38]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [5]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [39]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [5]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [5]
Methotrexate DM2TEOL Anterior urethra cancer Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [42]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [5]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [44]
Gefitinib DM15F0X Colon adenocarcinoma Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [47]
Etretinate DM2CZFA Keratosis ED56 Approved [48]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [50]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [51]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [53]
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Drug(s) Affected By Prothrombin (F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [58]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [59]
Phytonadione DM8HDOL Bleeding disorder GA20-GA21 Approved [60]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [61]
Testosterone enanthate DMB6871 N. A. N. A. Approved [62]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [63]
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Drug(s) Affected By Antileukoproteinase (SLPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [5]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [5]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [39]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [5]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [5]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [5]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [5]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [5]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [5]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Selenium DM25CGV N. A. N. A. Approved [66]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [68]
Epinephrine DM3KJBC Acute asthma CA23 Approved [69]
Quercetin DM3NC4M Obesity 5B81 Approved [70]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [71]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [72]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [73]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [75]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [76]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [77]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [78]
Cepharanthine DM9Y5JB N. A. N. A. Approved [79]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [80]
Clozapine DMFC71L Schizophrenia 6A20 Approved [81]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [82]
Trifluoperazine DMKBYWI Anxiety Approved [83]
Olanzapine DMPFN6Y Bipolar depression Approved [81]
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Drug(s) Affected By Hepatocyte growth factor receptor (MET)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cabozantinib DMIYDT4 Medullary thyroid gland carcinoma Approved [84]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [85]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [5]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [5]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [5]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [5]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [86]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [67]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [87]
Gefitinib DM15F0X Colon adenocarcinoma Approved [88]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [89]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [47]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [90]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [91]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [90]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [92]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [93]
Methotrexate DM2TEOL Anterior urethra cancer Approved [94]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [95]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [96]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [97]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [98]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [99]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [100]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [5]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [101]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [102]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [5]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [103]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [104]
Gefitinib DM15F0X Colon adenocarcinoma Approved [105]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [106]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [107]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [108]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [109]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [111]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [112]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [113]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [114]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [115]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [116]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [117]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [118]
Gefitinib DM15F0X Colon adenocarcinoma Approved [119]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [120]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [122]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [113]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [123]
Paclitaxel DMLB81S Breast carcinoma Approved [124]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [125]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [112]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [126]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [127]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [115]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [116]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [131]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [133]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [134]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [137]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [138]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [139]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [140]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [141]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [142]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [143]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [144]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Methotrexate DM2TEOL Anterior urethra cancer Approved [145]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [146]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [147]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Gefitinib DM15F0X Colon adenocarcinoma Approved [45]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [143]
Etretinate DM2CZFA Keratosis ED56 Approved [48]
Prednisone DM2HG4X Acute asthma CA23 Approved [150]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [91]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [151]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [152]
Gefitinib DM15F0X Colon adenocarcinoma Approved [153]
Prednisone DM2HG4X Acute asthma CA23 Approved [150]
Methotrexate DM2TEOL Anterior urethra cancer Approved [154]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [155]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [156]
Quercetin DM3NC4M Obesity 5B81 Approved [157]
Fluoxetine DM3PD2C Bipolar depression Approved [158]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [159]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [160]
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Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [162]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [162]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [163]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [164]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [162]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [162]
Ethacrynic acid DM60QMR Edema MG29 Approved [162]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
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Drug(s) Affected By Sodium channel protein type 5 subunit alpha (SCN5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [126]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [165]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [166]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [167]
Meloxicam DM2AR7L Arthritis FA20 Approved [168]
Quercetin DM3NC4M Obesity 5B81 Approved [169]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [170]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [171]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Retigabine DMGNYIH Behcet disease 4A62 Approved [173]
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Drug(s) Affected By PRKC apoptosis WT1 regulator protein (PAWR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [174]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [175]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [176]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
Leflunomide DMR8ONJ Arthritis FA20 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [61]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [180]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [181]
Bendamustine hydrochloride DMFH15Z leukaemia 2A60-2B33 Approved [182]
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Drug(s) Affected By Perilipin-2 (PLIN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [183]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [184]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [185]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [176]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [186]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [187]
Leflunomide DMR8ONJ Arthritis FA20 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [188]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [181]
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Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [190]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [190]
Gefitinib DM15F0X Colon adenocarcinoma Approved [191]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [126]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [192]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [193]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Quercetin DM3NC4M Obesity 5B81 Approved [195]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [196]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [197]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [198]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [199]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [200]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [201]
Capsaicin DMGMF6V Back pain ME84.Z Approved [202]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [203]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [204]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [203]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [199]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [126]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lactotransferrin (LTF) TTSZDQU TRFL_HUMAN Inhibitor [2]
Prostaglandin G/H synthase 2 (COX-2) TTVKILB PGH2_HUMAN Inhibitor [2]
TNF related apoptosis inducing ligand (TNFSF10) TTA5MS9 TNF10_HUMAN Modulator [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Antileukoproteinase (SLPI) OTUNFUU8 SLPI_HUMAN Gene/Protein Processing [5]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [6]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [7]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Gene/Protein Processing [8]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [9]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Protein Interaction/Cellular Processes [10]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [11]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Gene/Protein Processing [11]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Biotransformations [12]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [13]

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