Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWYE7A)

Drug Name
Protoporphyrin IX Drug Info
Synonyms
protoporphyrin IX; protoporphyrin; 553-12-8; Ooporphyrin; Protoporpyrin IX; Porphyrinogen IX; Protoporphyrin IX disodium; Kammerer's prophyrin; ppIX; Protoporphyrin IX (VAN); H2ppIX; Kammerer's porphyrin; MLS001074731; UNII-C2K325S808; NSC2632; NSC 2632; EINECS 209-033-7; 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid; SMR000127405; 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-; CHEMBL267548; CHEBI:15430; C34H34N4O4
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
4971
ChEBI ID
CHEMBL15430
CAS Number
CAS 553-12-8
TTD Drug ID
DMWYE7A
VARIDT Drug ID
DR01454

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Glutathione-dependent PGD synthase (HPGDS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Praziquantel DMOU1PK Flatworm infection 1F70-1F86 Approved [11]
HF-0220 DMI4C90 Alzheimer disease 8A20 Phase 2 [12]
Formic Acid DMNFZC6 Discovery agent N.A. Investigative [13]
Cibacron blue DMWE1N8 Discovery agent N.A. Investigative [14]
S-hexylglutathione DMNWP02 Discovery agent N.A. Investigative [15]
HQL-79 DMSHYQ3 Discovery agent N.A. Investigative [16]
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Drug(s) Transported By Breast cancer resistance protein (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Folic Acid DMEMBJC Colorectal carcinoma Approved [19]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [20]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [21]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [22]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [23]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [22]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [24]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [25]
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Drug(s) Affected By Ferritin heavy chain (FTH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [27]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [31]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [32]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [33]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [34]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [35]
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Drug(s) Affected By Sestrin-2 (SESN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [37]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Quercetin DM3NC4M Obesity 5B81 Approved [39]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [30]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [40]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [41]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [40]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [42]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [36]
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Drug(s) Affected By Maleylacetoacetate isomerase (GSTZ1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [43]
Quercetin DM3NC4M Obesity 5B81 Approved [44]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [46]
Testosterone DM7HUNW Hot flushes GA30 Approved [47]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [49]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [50]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [51]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [52]
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Drug(s) Affected By PRA1 family protein 3 (ARL6IP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [39]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [54]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [34]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [49]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [51]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [56]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [57]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [58]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [60]
Verapamil DMA7PEW Angina pectoris BA40 Approved [61]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [62]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [61]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [63]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [67]
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Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [68]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [69]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [70]
Diazepam DM08E9O Alcohol withdrawal Approved [4]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [71]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [72]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [73]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [74]
Methotrexate DM2TEOL Anterior urethra cancer Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [77]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Etretinate DM2CZFA Keratosis ED56 Approved [79]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [81]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [46]
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Drug(s) Affected By Involucrin (IVL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [86]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [43]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [87]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [88]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [89]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [86]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [90]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [91]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [92]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [43]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [93]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [95]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [97]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [98]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [97]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
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Drug(s) Affected By Erythroid transcription factor (GATA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [101]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [102]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [8]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
Aclarubicin DMLFZHD Acute myeloid leukaemia 2A60 Approved [104]
Pomalidomide DMTGBAX Plasma cell myeloma 2A83.1 Approved [105]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [106]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [107]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [108]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [109]
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Drug(s) Affected By 5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [110]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [111]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [111]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [112]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [113]
CATECHOL DML0YEK Discovery agent N.A. Investigative [114]
Butanoic Acid DMTAJP7 Discovery agent N.A. Investigative [115]
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Drug(s) Affected By Endothelial transcription factor GATA-2 (GATA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [98]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [116]
Panobinostat DM58WKG Chronic graft versus host disease Approved [117]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [102]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [8]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [118]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [50]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [58]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [112]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [119]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [120]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [121]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [122]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [123]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [124]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [125]
Gefitinib DM15F0X Colon adenocarcinoma Approved [126]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [127]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [128]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [129]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [120]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [130]
Paclitaxel DMLB81S Breast carcinoma Approved [131]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [132]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [119]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [69]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [133]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [122]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [123]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [134]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [60]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Gefitinib DM15F0X Colon adenocarcinoma Approved [136]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Etretinate DM2CZFA Keratosis ED56 Approved [139]
Prednisone DM2HG4X Acute asthma CA23 Approved [140]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [141]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [142]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [143]
Gefitinib DM15F0X Colon adenocarcinoma Approved [144]
Prednisone DM2HG4X Acute asthma CA23 Approved [140]
Methotrexate DM2TEOL Anterior urethra cancer Approved [145]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [146]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [147]
Quercetin DM3NC4M Obesity 5B81 Approved [148]
Fluoxetine DM3PD2C Bipolar depression Approved [149]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [151]
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Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [10]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [10]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [153]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [154]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [31]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [10]
Ethacrynic acid DM60QMR Edema MG29 Approved [10]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [10]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [155]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [156]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [157]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [158]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [159]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [160]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [161]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [162]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [163]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
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Drug(s) Affected By Transcription factor NF-E2 45 kDa subunit (NFE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [116]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [101]
Leflunomide DMR8ONJ Arthritis FA20 Approved [166]
Aclarubicin DMLFZHD Acute myeloid leukaemia 2A60 Approved [104]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [58]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [167]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [167]
Pomalidomide DMTGBAX Plasma cell myeloma 2A83.1 Approved [105]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [168]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endothelial PAS domain-containing protein 1 (EPAS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [115]
Methotrexate DM2TEOL Anterior urethra cancer Approved [169]
Quercetin DM3NC4M Obesity 5B81 Approved [170]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [171]
Panobinostat DM58WKG Chronic graft versus host disease Approved [117]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [172]
Leflunomide DMR8ONJ Arthritis FA20 Approved [166]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [49]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [50]
Ketorolac DMI4EL5 Postoperative inflammation 1A00-CA43.1 Approved [172]
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Drug(s) Affected By Heat shock protein HSP 90-alpha (HSP90AA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [173]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [133]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [174]
Gefitinib DM15F0X Colon adenocarcinoma Approved [175]
Selenium DM25CGV N. A. N. A. Approved [176]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [154]
Quercetin DM3NC4M Obesity 5B81 Approved [177]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [49]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glutathione-dependent PGD synthase (HPGDS) TTCYE56 HPGDS_HUMAN Inhibitor [1]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS2) OTJXOUCL HEM0_HUMAN Gene/Protein Processing [3]
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [4]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Protein Interaction/Cellular Processes [6]
Endothelial PAS domain-containing protein 1 (EPAS1) OTRE3O8U EPAS1_HUMAN Protein Interaction/Cellular Processes [7]
Endothelial transcription factor GATA-2 (GATA2) OTBP2QQ2 GATA2_HUMAN Gene/Protein Processing [8]
Erythroid transcription factor (GATA1) OTX1R7O1 GATA1_HUMAN Gene/Protein Processing [8]
Ferritin heavy chain (FTH1) OT6IFS0O FRIH_HUMAN Gene/Protein Processing [9]
Heat shock factor protein 1 (HSF1) OTYNJ4KP HSF1_HUMAN Gene/Protein Processing [10]

References

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2 Pharmacogenomic importance of ABCG2. Pharmacogenomics. 2008 Aug;9(8):1005-9.
3 Changes in DNA methylation of erythroid-specific genes in K562 cells exposed to phenol and hydroquinone. Toxicology. 2013 Oct 4;312:108-14. doi: 10.1016/j.tox.2013.08.007. Epub 2013 Aug 20.
4 The three recombinant domains of human serum albumin. Structural characterization and ligand binding properties. J Biol Chem. 1999 Oct 8;274(41):29303-10. doi: 10.1074/jbc.274.41.29303.
5 Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. Oncogene. 2004 Jan 15;23(2):503-13. doi: 10.1038/sj.onc.1207173.
6 Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium. Cancer Res. 2007 Feb 1;67(3):1007-18. doi: 10.1158/0008-5472.CAN-06-0235.
7 Structural requirements within protoporphyrin IX in the inhibition of heat shock protein 90. Chem Biol Interact. 2013 Jun 25;204(1):49-57. doi: 10.1016/j.cbi.2013.04.006. Epub 2013 Apr 24.
8 Phenolic metabolites of benzene inhibited the erythroid differentiation of K562 cells. Toxicol Lett. 2011 Jun 24;203(3):190-9. doi: 10.1016/j.toxlet.2011.03.012. Epub 2011 Mar 23.
9 The interaction of Hemin and Sestrin2 modulates oxidative stress and colon tumor growth. Toxicol Appl Pharmacol. 2019 Jul 1;374:77-85.
10 A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium. Chem Res Toxicol. 2021 Jul 19;34(7):1721-1737. doi: 10.1021/acs.chemrestox.0c00510. Epub 2021 Jun 25.
11 X-ray structure of glutathione S-transferase from Schistosoma japonicum in a new crystal form reveals flexibility of the substrate-binding site. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Mar 1;61(Pt 3):263-5.
12 US patent application no. 2009,0062,529, Multi-cyclic compounds.
13 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
14 A novel method for screening the glutathione transferase inhibitors. BMC Biochem. 2009 Mar 16;10:6.
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