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Doxepin FDA Label
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Fluoxetine FDA Label
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Olanzapine FDA Label
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Quetiapine FDA Label
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Genome-wide association study identifies 30 loci associated with bipolar disorder.Nat Genet. 2019 May;51(5):793-803. doi: 10.1038/s41588-019-0397-8. Epub 2019 May 1.
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Enhancing VTA Ca(v)1.3 L-type Ca(2+) channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. Mol Psychiatry. 2017 Dec;22(12):1735-1745. doi: 10.1038/mp.2017.9. Epub 2017 Feb 14.
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Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder. Pharmacopsychiatry. 2009 Jan;42(1):20-2. doi: 10.1055/s-0028-1085441. Epub 2009 Jan 19.
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Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium.Mol Psychiatry. 2004 Jun;9(6):609-20, 544. doi: 10.1038/sj.mp.4001471.
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GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum.Schizophr Res. 2005 Jan 1;72(2-3):109-22. doi: 10.1016/j.schres.2004.02.017.
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Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania.Mol Psychiatry. 2008 Sep;13(9):858-72. doi: 10.1038/mp.2008.20. Epub 2008 Mar 11.
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Genetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice.Behav Brain Res. 2012 Mar 17;228(2):406-14. doi: 10.1016/j.bbr.2011.12.026. Epub 2011 Dec 22.
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Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder.Mol Psychiatry. 2003 May;8(5):546-57. doi: 10.1038/sj.mp.4001268.
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Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances.Neuropsychopharmacology. 2010 Jul;35(8):1761-74. doi: 10.1038/npp.2010.43. Epub 2010 Mar 31.
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Glycogen synthase kinase 3 beta gene structural variants as possible risk factors of bipolar depression.Am J Med Genet B Neuropsychiatr Genet. 2014 Apr;165B(3):217-22. doi: 10.1002/ajmg.b.32223. Epub 2014 Feb 21.
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Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression.Prog Neuropsychopharmacol Biol Psychiatry. 2008 Dec 12;32(8):1863-6. doi: 10.1016/j.pnpbp.2008.08.017. Epub 2008 Sep 4.
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Carbohydrate metabolism in mania before and after lithium carbonate treatment.Arch Gen Psychiatry. 1970 Oct;23(4):310-9. doi: 10.1001/archpsyc.1970.01750040022004.
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The kynurenine pathway in major depression: haplotype analysis of three related functional candidate genes.Psychiatry Res. 2011 Aug 15;188(3):355-60. doi: 10.1016/j.psychres.2011.03.012. Epub 2011 Apr 13.
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Clinical and molecular genetics of psychotic depression.Schizophr Bull. 2013 Jul;39(4):766-75. doi: 10.1093/schbul/sbt040. Epub 2013 Mar 19.
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Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review.Am J Epidemiol. 2007 Jan 1;165(1):1-13. doi: 10.1093/aje/kwj347. Epub 2006 Oct 30.
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Vulnerability of conditional NCAM-deficient mice to develop stress-induced behavioral alterations.Stress. 2012 Mar;15(2):195-206. doi: 10.3109/10253890.2011.608226. Epub 2011 Sep 22.
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Combined serum levels of multiple proteins in tPA-BDNF pathway may aid the diagnosis of five mental disorders.Sci Rep. 2017 Jul 31;7(1):6871. doi: 10.1038/s41598-017-06832-6.
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PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia.Schizophr Res. 2008 Apr;101(1-3):36-49. doi: 10.1016/j.schres.2008.01.029. Epub 2008 Apr 3.
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Regionally specific changes in levels of cortical S100beta in bipolar 1 disorder but not schizophrenia.Aust N Z J Psychiatry. 2006 Mar;40(3):217-24. doi: 10.1080/j.1440-1614.2006.01777.x.
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Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse?.Neurotoxicology. 2007 Sep;28(5):899-914. doi: 10.1016/j.neuro.2007.05.011. Epub 2007 Jun 14.
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Serotonin transporter linked promoter (polymorphism) in the serotonin transporter gene may be associated with antidepressant-induced mania in bipolar disorder.Psychiatr Genet. 2006 Feb;16(1):25-9. doi: 10.1097/01.ypg.0000180684.26288.d7.
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NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD.J Psychopharmacol. 2010 Jan;24(1):27-38. doi: 10.1177/0269881108100255. Epub 2009 Feb 9.
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Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder.Brain Res. 2013 Jun 23;1517:16-27. doi: 10.1016/j.brainres.2013.04.025. Epub 2013 Apr 18.
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Association of the C(-1019)G 5-HT1A promoter polymorphism with exposure to stressors preceding hospitalization for bipolar depression.J Affect Disord. 2011 Jul;132(1-2):297-300. doi: 10.1016/j.jad.2011.02.024. Epub 2011 Mar 12.
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Sodium-myo-inositol co-transporter (SMIT-1) mRNA is increased in neutrophils of patients with bipolar 1 disorder and down-regulated under treatment with mood stabilizers.Int J Neuropsychopharmacol. 2007 Feb;10(1):63-71. doi: 10.1017/S1461145705006371. Epub 2006 Jan 18.
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AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder. J Affect Disord. 2011 Sep;133(1-2):346-51. doi: 10.1016/j.jad.2011.04.009. Epub 2011 May 12.
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Serum BICC1 levels are significantly different in various mood disorders.Neuropsychiatr Dis Treat. 2019 Jan 15;15:259-265. doi: 10.2147/NDT.S190048. eCollection 2019.
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The genetic association database.Nat Genet. 2004 May;36(5):431-2. doi: 10.1038/ng0504-431.
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Resequencing and association analysis of arylalkylamine N-acetyltransferase (AANAT) gene and its contribution to major depression susceptibility.J Pineal Res. 2010 Aug;49(1):35-44. doi: 10.1111/j.1600-079X.2010.00763.x. Epub 2010 Apr 29.
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Circadian polymorphisms in night owls, in bipolars, and in non-24-hour sleep cycles.Psychiatry Investig. 2014 Oct;11(4):345-62. doi: 10.4306/pi.2014.11.4.345. Epub 2014 Oct 20.
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CLOCK gene variants associated with the discrepancy between subjective and objective severity in bipolar depression.J Affect Disord. 2017 Mar 1;210:14-18. doi: 10.1016/j.jad.2016.12.007. Epub 2016 Dec 13.
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Disrupted in Schizophrenia 1 forms pathological aggresomes that disrupt its function in intracellular transport.Hum Mol Genet. 2012 May 1;21(9):2017-28. doi: 10.1093/hmg/dds018. Epub 2012 Jan 30.
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DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/-catenin signaling.Mol Psychiatry. 2018 Feb;23(2):467-475. doi: 10.1038/mp.2016.184. Epub 2016 Oct 18.
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Oxidative Stress and Accelerated Aging in Neurodegenerative and Neuropsychiatric Disorder.Curr Pharm Des. 2018;24(40):4711-4725. doi: 10.2174/1381612825666190115121018.
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Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia.Neurosci Res. 2009 Mar;63(3):199-204. doi: 10.1016/j.neures.2008.12.004. Epub 2008 Dec 24.
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Effects of Npas4 deficiency on anxiety, depression-like, cognition and sociability behaviour.Behav Brain Res. 2015 Mar 15;281:276-82. doi: 10.1016/j.bbr.2014.12.044. Epub 2014 Dec 27.
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Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder.Neuropsychopharmacology. 2008 Mar;33(4):933-45. doi: 10.1038/sj.npp.1301457. Epub 2007 May 16.
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Positron emission tomography quantification of serotonin-1A receptor binding in medication-free bipolar depression.Biol Psychiatry. 2009 Aug 1;66(3):223-30. doi: 10.1016/j.biopsych.2009.01.028. Epub 2009 Mar 17.
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Transcription factor SP4 is a susceptibility gene for bipolar disorder.PLoS One. 2009;4(4):e5196. doi: 10.1371/journal.pone.0005196. Epub 2009 Apr 9.
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Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia. Eur J Neurosci. 2005 Mar;21(6):1712-8. doi: 10.1111/j.1460-9568.2005.04002.x.
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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.Nat Genet. 2011 Sep 18;43(10):977-83. doi: 10.1038/ng.943.
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Thyrotrophin response to thyrotrophin-releasing hormone in unipolar and bipolar affective illness.J Affect Disord. 1981 Mar;3(1):9-16. doi: 10.1016/0165-0327(81)90014-8.
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