Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOF7AT)

Drug Name
Streptozocin Drug Info
Synonyms
Estreptozocina; STREPTOZOTOCIN; STRZ; Streptozocine; Streptozocinium; Streptozocinum; Streptozosin; Zanosar; Alkylating agent; Binds to DNA; Streptozocinium [Latin]; Streptozocine [INN-French]; Streptozocinum [INN-Latin]; Zanosar (TN); Streptozocin (USAN/INN); Streptozocin, Zanosar, STZ,Streptozotocin;N-(Methylnitrosocarbamoyl)-alpha-D-glucosamine; N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff; N-D-Glucosyl-(2)-N'-nitrosomethylurea; D-Glucose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)-(9CI); 1-methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea; 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose; 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose; 2-Deoxy-2[[(methylnitrosoamino)-carbonyl]amino]-D-glucopyranose; 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose
Indication
Disease Entry ICD 11 Status REF
Pancreatic cancer 2C10 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
29327
ChEBI ID
CHEBI:9288
CAS Number
CAS 18883-66-4
TTD Drug ID
DMOF7AT
ACDINA Drug ID
D01441

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Human Deoxyribonucleic acid (hDNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [8]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [9]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [10]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [11]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [12]
Carboplatin DMG281S Adenocarcinoma 2D40 Approved [13]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [14]
Procarbazine DMIK367 Hodgkin lymphoma 2B30 Approved [15]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [16]
Dacarbazine DMNPZL4 Adenocarcinoma 2D40 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAIAP2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [18]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [19]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [20]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [21]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [22]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [23]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [24]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [25]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [26]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Methylated-DNA--protein-cysteine methyltransferase (MGMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [27]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [28]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [19]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [30]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [21]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [31]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [32]
Dacarbazine DMNPZL4 Adenocarcinoma 2D40 Approved [33]
Topotecan DMP6G8T Central nervous system neoplasm Approved [34]
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Drug(s) Affected By DNA repair nuclease/redox regulator APEX1 (APEX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [21]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [37]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [38]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [25]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [40]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [41]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [42]
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Drug(s) Affected By Alpha-protein kinase 1 (ALPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [44]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [45]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [46]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [47]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [42]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [48]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [49]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [50]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [51]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [52]
Selenium DM25CGV N. A. N. A. Approved [53]
Methotrexate DM2TEOL Anterior urethra cancer Approved [54]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [55]
Epinephrine DM3KJBC Acute asthma CA23 Approved [56]
Quercetin DM3NC4M Obesity 5B81 Approved [57]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [58]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [59]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [60]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human Deoxyribonucleic acid (hDNA) TTUTN1I NOUNIPROTAC Breaker [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alpha-protein kinase 1 (ALPK1) OTBW6SGD ALPK1_HUMAN Drug Response [3]
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAIAP2L1) OTZ71SK9 BI2L1_HUMAN Drug Response [4]
DNA repair nuclease/redox regulator APEX1 (APEX1) OT53OI14 APEX1_HUMAN Drug Response [5]
Methylated-DNA--protein-cysteine methyltransferase (MGMT) OT40A9WH MGMT_HUMAN Drug Response [6]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Drug Response [7]

References

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