Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMP7LJH)

Drug Name
Thiocarbamate Drug Info
Synonyms GNVMUORYQLCPJZ-UHFFFAOYSA-M
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
21226412
TTD Drug ID
DMP7LJH

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Squalene monooxygenase (SQLE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Naftifine DMHVBG1 Dermatomycosis EA60 Approved [1]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [5]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [6]
FR-194738 DMNACIV Hypercholesterolaemia 5C80.0 Terminated [7]
SDZ-87-469 DMBY6CQ Coronary artery disease BA80 Terminated [5]
NB-598 DMJVTQN N. A. N. A. Terminated [8]
ELLAGIC ACID DMX8BS5 Discovery agent N.A. Investigative [6]
1,2,3,4,6-penta-O-galloyl-beta-D-glucose DMTK650 Discovery agent N.A. Investigative [6]
Pedunculagin DMKLRCX Discovery agent N.A. Investigative [6]
CORILAGIN DMAC698 Discovery agent N.A. Investigative [6]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [9]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [12]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [13]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [13]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [14]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [15]
Capsaicin DMGMF6V Back pain ME84.Z Approved [16]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [17]
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Drug(s) Affected By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fomepizole DM6VOWQ Athylene glycol or methanol poisoning NE61 Approved [18]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [19]
Theophylline DMRJFN9 Bronchitis CA20 Approved [20]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [21]
Ethanol DMDRQZU Chronic pain MG30 Approved [22]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [24]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Didanosine DMI2QPE Human immunodeficiency virus infection 1C62 Approved [20]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [26]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [27]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [28]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [29]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [30]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [20]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Verapamil DMA7PEW Angina pectoris BA40 Approved [32]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [33]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [34]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [35]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [36]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [37]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [38]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [39]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [40]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [42]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [43]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [45]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [46]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [33]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [48]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [50]
Meloxicam DM2AR7L Arthritis FA20 Approved [51]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [52]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [53]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [27]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [45]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Verapamil DMA7PEW Angina pectoris BA40 Approved [32]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [54]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [48]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Meloxicam DM2AR7L Arthritis FA20 Approved [57]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [58]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Squalene monooxygenase (SQLE) TTE14XG ERG1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [2]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [2]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [2]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [2]
Cytochrome P450 2E1 (CYP2E1) OTHQ17JG CP2E1_HUMAN Gene/Protein Processing [3]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [4]

References

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