General Information of Drug (ID: DMQRSMD)

Drug Name
Trequinsin Drug Info
Synonyms
trequinsin; Trequinsin [INN]; Trequinsinum [INN-Latin]; Trequinsine [INN-French]; 79855-88-2; UNII-739I2958C1; CHEMBL285913; (2e)-2-(mesitylimino)-9,10-dimethoxy-3-methyl-2,3,6,7-tetrahydro-4h-pyrimido[6,1-a]isoquinolin-4-one; 739I2958C1; Trequinsinum; Trequinsine; C24H27N3O3; 2,3,6,7-Tetrahydro-2-(mesitylimino)-9,10-dimethoxy-3-methyl-4H-pyrimido(6,1-a)isoquinolin-4-one; AC1L1KKE; AC1Q6LSV; Lopac-T-2057; Lopac0_001165; KBioGR_000072; KBioSS_000072; BSPBio_001352; SCHEMBL2777196; SCHEMBL2396911; CHEMBL588593; CHEMBL1411581
Cross-matching ID
PubChem CID
5537
ChEBI ID
CHEBI:93477
CAS Number
CAS 79855-88-2
TTD Drug ID
DMQRSMD
VARIDT Drug ID
DR00496

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tadalafil DMJZHT1 Benign prostatic hyperplasia GA90 Approved [3]
Udenafil DM1IQRP Erectile dysfunction HA01.1 Approved [4]
Vardenafil DMTBGW8 Cystic fibrosis CA25 Approved [5]
Dipyridamole DMXY30O Atrial fibrillation BC81.3 Approved [6]
Papaverine DMCA9QP Brain ischaemia 8B1Z Approved [7]
Avanafil DM75CXN Erectile dysfunction HA01.1 Approved [8]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [9]
ICARIIN DMOJQGT N. A. N. A. Phase 3 [10]
EXISULIND DMBY56U Colorectal cancer 2B91.Z Phase 3 [11]
PF-489791 DM3C8GQ Chronic obstructive pulmonary disease CA22 Phase 2 [12]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [15]
Roflumilast DMPGHY8 Asthma CA23 Approved [2]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [16]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [18]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [19]
[3H]cAMP DMZRQU7 Discovery agent N.A. Investigative [20]
⏷ Show the Full List of 9 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivacaftor DMZC1HS Cystic fibrosis CA25 Approved [21]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [23]
Quercetin DM3NC4M Obesity 5B81 Approved [24]
Miglustat DM5J64S Niemann-Pick disease type C Approved [25]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [26]
Milrinone DM8TUPF Congestive heart failure BD10 Approved [23]
Oxidized glutathione DM9EQC0 Breast cancer 2C60-2C65 Approved [27]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Folic Acid DMEMBJC Colorectal carcinoma Approved [31]
Roflumilast DMPGHY8 Asthma CA23 Approved [2]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [32]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [33]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [35]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [36]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [38]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [39]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [40]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [43]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [44]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [45]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [46]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [49]
Roflumilast DMPGHY8 Asthma CA23 Approved [2]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [32]
Arsenic DMTL2Y1 N. A. N. A. Approved [50]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [51]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [52]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [53]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [18]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Panobinostat DM58WKG Chronic graft versus host disease Approved [35]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [54]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [55]
Leflunomide DMR8ONJ Arthritis FA20 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [57]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [58]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Roflumilast DMPGHY8 Asthma CA23 Approved [2]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [60]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [61]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [35]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [62]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [63]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Bortezomib DMNO38U Leukemia Approved [64]
Roflumilast DMPGHY8 Asthma CA23 Approved [2]
Arsenic DMTL2Y1 N. A. N. A. Approved [65]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [18]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [35]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [66]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [66]
Leflunomide DMR8ONJ Arthritis FA20 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [57]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [67]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [68]
Roflumilast DMPGHY8 Asthma CA23 Approved [2]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [32]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 5A (PDE5A) TTJ0IQB PDE5A_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3',5'-cyclic-AMP phosphodiesterase 4A (PDE4A) OTMUUZLF PDE4A_HUMAN Gene/Protein Processing [2]
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B) OTOA8WU2 PDE4B_HUMAN Gene/Protein Processing [2]
3',5'-cyclic-AMP phosphodiesterase 4C (PDE4C) OTI8VMHZ PDE4C_HUMAN Gene/Protein Processing [2]
3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D) OT1RWFV0 PDE4D_HUMAN Gene/Protein Processing [2]
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (PDE3A) OTKUW1WT PDE3A_HUMAN Gene/Protein Processing [2]
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (PDE3B) OT1GI1TE PDE3B_HUMAN Gene/Protein Processing [2]
Cystic fibrosis transmembrane conductance regulator (CFTR) OT6B22QH CFTR_HUMAN Gene/Protein Processing [2]
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (PDE7A) OTVDV4IT PDE7A_HUMAN Gene/Protein Processing [2]
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (PDE8B) OT4217NK PDE8B_HUMAN Gene/Protein Processing [2]

References

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